JP2009513681A - キナーゼおよびユビキネーションアッセイ法 - Google Patents

キナーゼおよびユビキネーションアッセイ法 Download PDF

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JP2009513681A
JP2009513681A JP2008538212A JP2008538212A JP2009513681A JP 2009513681 A JP2009513681 A JP 2009513681A JP 2008538212 A JP2008538212 A JP 2008538212A JP 2008538212 A JP2008538212 A JP 2008538212A JP 2009513681 A JP2009513681 A JP 2009513681A
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test sample
substrate
protein
ubiquitin
polypeptide
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Japanese (ja)
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JP2009513681A5 (enExample
Inventor
カート ウィリアム フォーゲル
スティーブン マイケル リドル
ロバート アロン ホートン
マシュー ブライアン ロバース
グレゴリー アレン ミショー
トーマス マッハライト
ケビン ベドビック
クリスティン ジー フウィラー
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インヴィトロジェン コーポレーション
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Publication of JP2009513681A5 publication Critical patent/JP2009513681A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2008538212A 2005-10-28 2006-10-30 キナーゼおよびユビキネーションアッセイ法 Withdrawn JP2009513681A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US73131005P 2005-10-28 2005-10-28
US73581205P 2005-11-14 2005-11-14
US75954506P 2006-01-18 2006-01-18
US77423606P 2006-02-17 2006-02-17
US83211406P 2006-07-21 2006-07-21
PCT/US2006/060373 WO2007051207A2 (en) 2005-10-28 2006-10-30 Kinase and ubiquination assays

Publications (2)

Publication Number Publication Date
JP2009513681A true JP2009513681A (ja) 2009-04-02
JP2009513681A5 JP2009513681A5 (enExample) 2010-12-24

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JP2008538212A Withdrawn JP2009513681A (ja) 2005-10-28 2006-10-30 キナーゼおよびユビキネーションアッセイ法

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US (2) US20070264678A1 (enExample)
EP (2) EP1955071A4 (enExample)
JP (1) JP2009513681A (enExample)
WO (1) WO2007051207A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7619059B2 (en) 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
CA2445420A1 (en) 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
JP2007505315A (ja) * 2003-09-12 2007-03-08 インヴィトロジェン コーポレーション 多重結合および活性アッセイ
EP1955071A4 (en) 2005-10-28 2009-03-18 Invitrogen Corp ASSAYS OF ACTIVITY KINASE AND UBIQUITINATION
JP2009215238A (ja) * 2008-03-11 2009-09-24 Osaka Univ 希土類発光プローブ
JP5774471B2 (ja) 2008-03-27 2015-09-09 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ シアノベンゾチアゾールコンジュゲートによるタンパク質標識
DE102008024567A1 (de) * 2008-05-21 2009-12-03 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin Verfahren zur Messung einer Konzentration einer Messsubstanz in einer biologischen Probe
EP2154533A1 (en) * 2008-08-04 2010-02-17 Medizinische Hochschule Hannover Method for determining SUMOylation
WO2010044892A1 (en) * 2008-10-17 2010-04-22 President And Fellows Of Harvard College Diagnostic method based on large scale identification of post-translational modification of proteins
WO2010127980A1 (en) * 2009-05-05 2010-11-11 F. Hoffmann-La Roche Ag Fret-based binding assay
WO2011090159A1 (ja) * 2010-01-22 2011-07-28 独立行政法人科学技術振興機構 蛋白質の分解活性を測定するためのプローブ試薬
US20140178895A1 (en) * 2011-03-23 2014-06-26 Saurabh Rajendra Nirantar Recombinant protein biosensors and a method for detecting the presence of an analyte molecule
JP2014527087A (ja) * 2011-03-31 2014-10-09 エンバイロメンタル テクノロジー ソリューションズ エルエルシー 変化検出能力を高めるためのポリマーおよび役割に応じて官能化されたポリマー
WO2014179494A1 (en) * 2013-04-30 2014-11-06 Colorado State University Research Foundation Sensors and assays for ubiquitin or ubiquitin-like proteins
GB201417288D0 (en) 2014-09-30 2014-11-12 Univ Dundee Cysteine labelling
US10167496B2 (en) 2015-10-01 2019-01-01 The Uab Research Foundation SUMOylation assay and related reagents

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570703B1 (fr) 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US5220012A (en) 1984-09-26 1993-06-15 Compagnie Oris Industrie Sa Macropolycyclic rare earth complexes and application as fluorescent tracers
US5162508A (en) 1987-12-18 1992-11-10 Compagnie Oris Industrie Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers
US5571897A (en) 1991-12-05 1996-11-05 Wallac Oy Luminescent lanthanide chelates
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5622821A (en) 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
US6162931A (en) 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
AU768859B2 (en) 1999-07-29 2004-01-08 Dyax Corp. Binding moieties for fibrin
JP2003505519A (ja) 1999-07-29 2003-02-12 エピックス メディカル， インコーポレイテッド 多座結合を介した多量体画像化剤の標的化
GB9927331D0 (en) * 1999-11-18 2000-01-12 Fluorescience Ltd Assay for measuring enzyme activity in vivo
US20040214227A1 (en) 1999-12-22 2004-10-28 Erik Joly Bioluminescence resonance energy transfer (bret) fusion molecule and method of use
GB0007915D0 (en) * 2000-03-31 2000-05-17 Univ Bristol Protein kinase assay
DE10029210A1 (de) * 2000-06-14 2002-01-31 Vasopharm Biotech Gmbh & Co Kg Testsystem sowie dessen Verwendung
TWI240632B (en) 2001-07-30 2005-10-01 Epix Medical Inc Purified peptides for peptide-based multimeric targeted contrast agents
US20040053324A1 (en) * 2002-08-30 2004-03-18 Brian Wong Assays and compositions for identifying agents that modulate the activity of deubiquitinating agents
EP1498133A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma Deutschland GmbH Use of a pak inhibitor for the treatment of a joint disease
CA2445420A1 (en) 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US7619059B2 (en) 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
JP2007505315A (ja) * 2003-09-12 2007-03-08 インヴィトロジェン コーポレーション 多重結合および活性アッセイ
EP1955071A4 (en) 2005-10-28 2009-03-18 Invitrogen Corp ASSAYS OF ACTIVITY KINASE AND UBIQUITINATION

Also Published As

Publication number Publication date
WO2007051207A3 (en) 2007-07-19
EP1955071A4 (en) 2009-03-18
EP2221385A3 (en) 2010-12-01
EP1955071A2 (en) 2008-08-13
US8642256B2 (en) 2014-02-04
US20100151484A1 (en) 2010-06-17
US20070264678A1 (en) 2007-11-15
EP2221385A2 (en) 2010-08-25
WO2007051207A2 (en) 2007-05-03

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