|
US4237130A
(en)
*
|
1979-06-21 |
1980-12-02 |
Merck & Co., Inc. |
2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids
|
|
US4600709A
(en)
*
|
1982-10-22 |
1986-07-15 |
Ciba-Geigy Ag |
Benzodioxole derivatives, processes for the manufacture thereof and corresponding pharmaceutical compositions
|
|
DE3374408D1
(en)
*
|
1982-10-22 |
1987-12-17 |
Ciba Geigy Ag |
Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them
|
|
EP0158596A3
(de)
*
|
1984-04-06 |
1986-08-13 |
Ciba-Geigy Ag |
Neue substituierte Benzodioxolderivate, Verfahren zu deren Herstellung und entsprechende pharmazeutische Zusammensetzungen
|
|
CN1014148B
(zh)
*
|
1984-09-05 |
1991-10-02 |
盐野义制药株式会社 |
2,3-二氢苯并呋喃-5-磺酰胺衍生物的制备方法
|
|
JPS6163671A
(ja)
|
1984-09-05 |
1986-04-01 |
Shionogi & Co Ltd |
2,3−ジヒドロベンゾフラン−5−スルホンアミド誘導体および降圧利尿剤
|
|
JPH05255089A
(ja)
|
1991-12-18 |
1993-10-05 |
Sanwa Kagaku Kenkyusho Co Ltd |
抗ウイルス剤
|
|
US5464788A
(en)
|
1994-03-24 |
1995-11-07 |
Merck & Co., Inc. |
Tocolytic oxytocin receptor antagonists
|
|
GB9600464D0
(en)
|
1996-01-09 |
1996-03-13 |
Smithkline Beecham Plc |
Novel method
|
|
PE86199A1
(es)
|
1997-06-17 |
1999-09-24 |
Schering Corp |
Sulfonamida inhibidor de la enzima farnesilo transferasa
|
|
TR200002182T2
(tr)
|
1998-01-27 |
2000-12-21 |
Aventis Pharmaceuticals Products Inc. |
İkame edilmiş aksozaherosayklil faktör xa inhibitörleri
|
|
US7517884B2
(en)
*
|
1998-03-30 |
2009-04-14 |
Kalypsys Inc. |
Sulfonyl-substituted bicyclic compounds as modulators of PPAR
|
|
CA2342251A1
(en)
|
1998-08-28 |
2000-03-09 |
Scios Inc. |
Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase
|
|
ES2300151T3
(es)
|
1998-09-22 |
2008-06-01 |
Astellas Pharma Inc. |
Derivados de cianofenilo.
|
|
WO2000056704A1
(en)
|
1999-03-22 |
2000-09-28 |
Darwin Discovery Limited |
Hydroxamic and carboxylic acid derivatives
|
|
EP1236719A4
(en)
*
|
1999-12-03 |
2003-06-25 |
Kyoto Pharma Ind |
NOVEL HETEROCYCLIC COMPOUNDS AND SALTS THEREOF, USE OF THESE COMPOUNDS IN MEDICINE
|
|
JP2001261657A
(ja)
|
2000-03-17 |
2001-09-26 |
Yamanouchi Pharmaceut Co Ltd |
シアノフェニル誘導体
|
|
GB0007907D0
(en)
|
2000-03-31 |
2000-05-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2423744C
(en)
|
2000-09-29 |
2012-04-03 |
Prolifix Limited |
Hydroxamic acid compounds comprising a sulfonamide linkage as hdac inhibitors
|
|
WO2002051836A1
(en)
|
2000-12-27 |
2002-07-04 |
Kyowa Hakko Kogyo Co., Ltd. |
Dipeptidyl peptidase iv inhibitor
|
|
IL158590A0
(en)
|
2001-06-11 |
2004-05-12 |
Biovitrum Ab |
Substituted sulfonamide compounds, process for their use as medicament for the treatment of cns disorders, obesity and type ii diabetes
|
|
US7456184B2
(en)
|
2003-05-01 |
2008-11-25 |
Palatin Technologies Inc. |
Melanocortin receptor-specific compounds
|
|
CA2479906C
(en)
|
2002-04-03 |
2011-02-08 |
Topotarget Uk Limited |
Carbamic acid compounds comprising a piperazine linkage as hdac inhibitors
|
|
US6875780B2
(en)
|
2002-04-05 |
2005-04-05 |
Warner-Lambert Company |
Compounds that modulate PPAR activity and methods for their preparation
|
|
CN1181065C
(zh)
|
2002-05-08 |
2004-12-22 |
上海医药工业研究院 |
芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用
|
|
EP1511488B1
(en)
|
2002-06-12 |
2013-05-22 |
Symphony Evolution, Inc. |
Human adam-10 inhibitors
|
|
CN1751037A
(zh)
|
2003-02-14 |
2006-03-22 |
伊莱利利公司 |
作为ppar调节剂的磺酰胺衍生物
|
|
CA2521175A1
(en)
|
2003-04-07 |
2004-10-28 |
Kalypsys, Inc. |
Para-sulfonyl substituted phenyl compounds as modulators of ppars
|
|
US20070208026A1
(en)
|
2003-04-07 |
2007-09-06 |
Liu Kevin |
N-Containing Heteroaromatic Compounds As Modulators Of Ppars And Methods Of Treating Metabolic Disorders
|
|
KR100762762B1
(ko)
|
2003-04-17 |
2007-10-17 |
칼립시스, 인코포레이티드 |
Ppar의 조절인자로서의 아릴 화합물 및 신진대사장애의 치료 방법
|
|
MXPA06001202A
(es)
|
2003-07-29 |
2006-08-31 |
Xenon Pharmaceuticals Inc |
Derivados piridilo y su uso como agentes terapeuticos.
|
|
KR20060036106A
(ko)
|
2003-07-30 |
2006-04-27 |
제논 파마슈티칼스 인크. |
피리딜 유도체 및 그의 치료제로서의 용도
|
|
CN1829701A
(zh)
|
2003-07-30 |
2006-09-06 |
泽农医药公司 |
哌嗪衍生物和它们作为治疗剂的用途
|
|
CN101712653A
(zh)
|
2003-07-30 |
2010-05-26 |
泽农医药公司 |
哒嗪衍生物和它们作为治疗剂的用途
|
|
DE10335449A1
(de)
*
|
2003-08-02 |
2005-02-17 |
Bayer Healthcare Ag |
Bicyclische Indolinsulfonamid-Derivate
|
|
US20050124625A1
(en)
|
2003-10-21 |
2005-06-09 |
Salvati Mark E. |
Piperazine derivatives and their use as modulators of nuclear hormone receptor function
|
|
GB0325956D0
(en)
|
2003-11-06 |
2003-12-10 |
Addex Pharmaceuticals Sa |
Novel compounds
|
|
WO2005060958A1
(en)
|
2003-12-19 |
2005-07-07 |
Kalypsys, Inc. |
(5- (2-phenyl)-thiazol-5-ylmethoxy)-indol-1-yl) -acetic acid derivatives and related compounds as modulators of the human ppar-delta receptor for the treatment of metabolic disorders such as type 2 diabetes
|
|
AR048523A1
(es)
|
2004-04-07 |
2006-05-03 |
Kalypsys Inc |
Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos
|
|
CA2573198A1
(en)
|
2004-07-06 |
2006-02-09 |
Xenon Pharmaceuticals Inc. |
Nicotinamide derivatives and their use as therapeutic agents
|
|
JP5080256B2
(ja)
|
2004-09-20 |
2012-11-21 |
ゼノン・ファーマシューティカルズ・インコーポレイテッド |
二環式複素環誘導体およびステアロイル−CoAデサチュラーゼ(SCD)のインヒビターとしてのそれらの使用
|
|
AU2005286648A1
(en)
|
2004-09-20 |
2006-03-30 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
|
|
US7829712B2
(en)
|
2004-09-20 |
2010-11-09 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
|
|
AR051091A1
(es)
|
2004-09-20 |
2006-12-20 |
Xenon Pharmaceuticals Inc |
Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
|
|
EP2289510A1
(en)
|
2004-09-20 |
2011-03-02 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
|
|
EP1807085B1
(en)
|
2004-09-20 |
2013-08-21 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
CA2580762A1
(en)
|
2004-09-20 |
2006-03-30 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as therapeutic agents
|
|
EP1827438B2
(en)
|
2004-09-20 |
2014-12-10 |
Xenon Pharmaceuticals Inc. |
Piperazin derivatives for inhibiting human stearoyl-coa-desaturase
|
|
US20070190079A1
(en)
|
2004-10-29 |
2007-08-16 |
Kalypsys, Inc. |
Methods for the selective modulation of ppar
|
|
MX2007005205A
(es)
*
|
2004-10-29 |
2007-05-11 |
Kalypsys Inc |
Compuestos biciclicos sulfonilo-sustituidos como moduladores de receptores activados por el proliferador de la peroxisoma.
|
|
WO2007047432A1
(en)
|
2005-10-12 |
2007-04-26 |
Kalypsys, Inc. |
Sulfonamide derivatives as modulators of ppar
|
|
US20090143396A1
(en)
|
2005-10-12 |
2009-06-04 |
Malecha James W |
Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors
|
|
EP1996198A1
(en)
|
2006-03-17 |
2008-12-03 |
Kalypsys, Inc. |
Alkylamine-substituted bicyclic aryl compounds useful as modulators of ppar
|
|
US20070249519A1
(en)
|
2006-04-20 |
2007-10-25 |
Kalypsys, Inc. |
Methods for the upregulation of glut4 via modulation of ppar delta in adipose tissue and for the treatment of disease
|
|
US20080004281A1
(en)
|
2006-06-28 |
2008-01-03 |
Kalypsys, Inc. |
Methods for the modulation of crp by the selective modulation of ppar delta
|
|
WO2008043024A2
(en)
|
2006-10-04 |
2008-04-10 |
Kalypsys, Inc. |
Oral pharmaceutical formulation comprising a sulfonyl bicyclic modulator of ppar for the treatment of disease
|
|
US20080287477A1
(en)
|
2006-10-11 |
2008-11-20 |
Kalypsys, Inc. |
Novel Compounds as Modulators of Ppar
|
|
WO2008091863A1
(en)
|
2007-01-23 |
2008-07-31 |
Kalypsys, Inc. |
Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis
|