DE602006005488D1 - Verfahren zur herstellung von losartanderivaten durch chlorierung und reduktion der entsprechenden 1h-imidazol-5-carbaldehyde - Google Patents

Verfahren zur herstellung von losartanderivaten durch chlorierung und reduktion der entsprechenden 1h-imidazol-5-carbaldehyde

Info

Publication number
DE602006005488D1
DE602006005488D1 DE602006005488T DE602006005488T DE602006005488D1 DE 602006005488 D1 DE602006005488 D1 DE 602006005488D1 DE 602006005488 T DE602006005488 T DE 602006005488T DE 602006005488 T DE602006005488 T DE 602006005488T DE 602006005488 D1 DE602006005488 D1 DE 602006005488D1
Authority
DE
Germany
Prior art keywords
preparation
formula
reducing
losary
chloring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006005488T
Other languages
English (en)
Inventor
Berta Kotar Jordan
Martin Putala
Alexander Bartovic
Eva Veverkova
Miroslav Kriz
Miroslav Veverka
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KRKA dd
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KRKA dd
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Application filed by KRKA dd filed Critical KRKA dd
Publication of DE602006005488D1 publication Critical patent/DE602006005488D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
DE602006005488T 2005-07-04 2006-06-22 Verfahren zur herstellung von losartanderivaten durch chlorierung und reduktion der entsprechenden 1h-imidazol-5-carbaldehyde Active DE602006005488D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05014451A EP1741711A1 (de) 2005-07-04 2005-07-04 Verfahren zur Herstellung von Losartanderivaten durch Chlorierung und Reduktion der entsprechenden 1H-imidazol-5-carbaldehyde
PCT/EP2006/006040 WO2007003280A1 (en) 2005-07-04 2006-06-22 A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1h-imidazole-5-carbaldehydes

Publications (1)

Publication Number Publication Date
DE602006005488D1 true DE602006005488D1 (de) 2009-04-16

Family

ID=35395891

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006005488T Active DE602006005488D1 (de) 2005-07-04 2006-06-22 Verfahren zur herstellung von losartanderivaten durch chlorierung und reduktion der entsprechenden 1h-imidazol-5-carbaldehyde

Country Status (6)

Country Link
EP (2) EP1741711A1 (de)
AT (1) ATE424397T1 (de)
DE (1) DE602006005488D1 (de)
NO (1) NO20080607L (de)
SI (1) SI1899328T1 (de)
WO (1) WO2007003280A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102786399A (zh) * 2011-05-16 2012-11-21 湖南斯威森生化技术有限公司 一种本芴醇中间体2,7-二氯-4-氯乙酰芴新合成方法
CN113929666A (zh) * 2021-09-30 2022-01-14 宁波美诺华药业股份有限公司 一种洛沙坦立体异构体杂质合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132633A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Cyclisch substituierte imidazolyl-propensaeurederivate
DE60304175T2 (de) * 2002-04-29 2007-03-15 Teva Pharmaceutical Industries Ltd. Verfahren zur herstellung von losartan und losartan-kaliumsalz
ITMI20032069A1 (it) * 2003-10-23 2005-04-24 Dinamite Dipharma S P A In Forma A Bbreviata Diph Procedimento per la preparazione di derivati benzilmidazolici.

Also Published As

Publication number Publication date
EP1899328A1 (de) 2008-03-19
SI1899328T1 (sl) 2009-06-30
NO20080607L (no) 2008-02-01
EP1741711A1 (de) 2007-01-10
ATE424397T1 (de) 2009-03-15
EP1899328B1 (de) 2009-03-04
WO2007003280A1 (en) 2007-01-11

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Legal Events

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8364 No opposition during term of opposition