JP2009513606A5 - - Google Patents
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- Publication number
- JP2009513606A5 JP2009513606A5 JP2008537112A JP2008537112A JP2009513606A5 JP 2009513606 A5 JP2009513606 A5 JP 2009513606A5 JP 2008537112 A JP2008537112 A JP 2008537112A JP 2008537112 A JP2008537112 A JP 2008537112A JP 2009513606 A5 JP2009513606 A5 JP 2009513606A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxy
- phenyl
- methyl
- benzenesulfonylamino
- ethylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 31
- -1 hydroxy, methoxy Chemical group 0.000 claims 23
- 150000003839 salts Chemical class 0.000 claims 11
- FEOUBAYQXHYVTQ-UHFFFAOYSA-N 1-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]benzimidazole-5-carboxylic acid Chemical compound C1=NC2=CC(C(O)=O)=CC=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 FEOUBAYQXHYVTQ-UHFFFAOYSA-N 0.000 claims 7
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 7
- 229910052801 chlorine Inorganic materials 0.000 claims 7
- 239000000460 chlorine Chemical group 0.000 claims 7
- 229910052731 fluorine Inorganic materials 0.000 claims 7
- 239000011737 fluorine Substances 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 6
- OUDTVESPNOMJHI-UHFFFAOYSA-N ethyl 1-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]benzimidazole-5-carboxylate Chemical compound C1=NC2=CC(C(=O)OCC)=CC=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 OUDTVESPNOMJHI-UHFFFAOYSA-N 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 125000001246 bromo group Chemical group Br* 0.000 claims 5
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- LMWJQVTYANHCIM-UHFFFAOYSA-N n-[3-[2-[[4-(5-aminobenzimidazol-1-yl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]phenyl]benzenesulfonamide Chemical compound C1=NC2=CC(N)=CC=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 LMWJQVTYANHCIM-UHFFFAOYSA-N 0.000 claims 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 4
- 239000013543 active substance Substances 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 125000003277 amino group Chemical group 0.000 claims 4
- FEOUBAYQXHYVTQ-VWLOTQADSA-N 1-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]benzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC=C(C=C3N=C2)C(O)=O)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 FEOUBAYQXHYVTQ-VWLOTQADSA-N 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 239000012453 solvate Substances 0.000 claims 3
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims 3
- ISKUURKCGKMQGQ-VWLOTQADSA-N 3-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]benzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC(=CC=C3N=C2)C(O)=O)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 ISKUURKCGKMQGQ-VWLOTQADSA-N 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- FIHDRABZAAQKJG-UHFFFAOYSA-N n-[3-[2-[[4-(6-aminobenzimidazol-1-yl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]phenyl]benzenesulfonamide Chemical compound C1=NC2=CC=C(N)C=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 FIHDRABZAAQKJG-UHFFFAOYSA-N 0.000 claims 2
- 230000000638 stimulation Effects 0.000 claims 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 claims 1
- 125000006698 (C1-C3) dialkylamino group Chemical group 0.000 claims 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- SILNNFMWIMZVEQ-JZRMKITLSA-N 1,3-dihydrobenzimidazol-2-one Chemical group C1=CC=C2N[11C](=O)NC2=C1 SILNNFMWIMZVEQ-JZRMKITLSA-N 0.000 claims 1
- OIQFJYZHJGRDOB-QHCPKHFHSA-N 1-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-4-chlorobenzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC=C(C(Cl)=C3N=C2)C(O)=O)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 OIQFJYZHJGRDOB-QHCPKHFHSA-N 0.000 claims 1
- VKMKJTBPKPJAIJ-VWLOTQADSA-N 1-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-chlorobenzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC(Cl)=C(C(O)=O)C=C3N=C2)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 VKMKJTBPKPJAIJ-VWLOTQADSA-N 0.000 claims 1
- KPUYFRHQLDMBNW-VWLOTQADSA-N 1-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-hydroxybenzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC(O)=C(C(O)=O)C=C3N=C2)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 KPUYFRHQLDMBNW-VWLOTQADSA-N 0.000 claims 1
- IWZSMSOBKJMUIB-VWLOTQADSA-N 1-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-methoxybenzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(C)CCN2C=3C=C(C(=CC=3N=C2)C(O)=O)OC)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 IWZSMSOBKJMUIB-VWLOTQADSA-N 0.000 claims 1
- OIQFJYZHJGRDOB-UHFFFAOYSA-N 1-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-4-chlorobenzimidazole-5-carboxylic acid Chemical compound C1=NC2=C(Cl)C(C(O)=O)=CC=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 OIQFJYZHJGRDOB-UHFFFAOYSA-N 0.000 claims 1
- VKMKJTBPKPJAIJ-UHFFFAOYSA-N 1-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-chlorobenzimidazole-5-carboxylic acid Chemical compound C1=NC2=CC(C(O)=O)=C(Cl)C=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 VKMKJTBPKPJAIJ-UHFFFAOYSA-N 0.000 claims 1
- KPUYFRHQLDMBNW-UHFFFAOYSA-N 1-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-hydroxybenzimidazole-5-carboxylic acid Chemical compound C1=NC2=CC(C(O)=O)=C(O)C=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 KPUYFRHQLDMBNW-UHFFFAOYSA-N 0.000 claims 1
- IWZSMSOBKJMUIB-UHFFFAOYSA-N 1-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-methoxybenzimidazole-5-carboxylic acid Chemical compound C1=NC=2C=C(C(O)=O)C(OC)=CC=2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 IWZSMSOBKJMUIB-UHFFFAOYSA-N 0.000 claims 1
- 125000004173 1-benzimidazolyl group Chemical group [H]C1=NC2=C([H])C([H])=C([H])C([H])=C2N1* 0.000 claims 1
- XLNVCXIQJAMZSB-QHCPKHFHSA-N 3-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-4-chlorobenzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=C(Cl)C(C(O)=O)=CC=C3N=C2)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 XLNVCXIQJAMZSB-QHCPKHFHSA-N 0.000 claims 1
- YZTYUSDPESXYFY-VWLOTQADSA-N 3-[3-[[(2r)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-chlorobenzimidazole-5-carboxylic acid Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC(=C(Cl)C=C3N=C2)C(O)=O)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 YZTYUSDPESXYFY-VWLOTQADSA-N 0.000 claims 1
- XLNVCXIQJAMZSB-UHFFFAOYSA-N 3-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-4-chlorobenzimidazole-5-carboxylic acid Chemical compound C1=NC2=CC=C(C(O)=O)C(Cl)=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 XLNVCXIQJAMZSB-UHFFFAOYSA-N 0.000 claims 1
- YZTYUSDPESXYFY-UHFFFAOYSA-N 3-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]-6-chlorobenzimidazole-5-carboxylic acid Chemical compound C1=NC2=CC(Cl)=C(C(O)=O)C=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 YZTYUSDPESXYFY-UHFFFAOYSA-N 0.000 claims 1
- ISKUURKCGKMQGQ-UHFFFAOYSA-N 3-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]benzimidazole-5-carboxylic acid Chemical compound C1=NC2=CC=C(C(O)=O)C=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 ISKUURKCGKMQGQ-UHFFFAOYSA-N 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 101710204865 Tyrosine-protein phosphatase 1 Proteins 0.000 claims 1
- 230000001800 adrenalinergic effect Effects 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 230000003178 anti-diabetic effect Effects 0.000 claims 1
- 125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Chemical group 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 230000001906 cholesterol absorption Effects 0.000 claims 1
- 230000002074 deregulated effect Effects 0.000 claims 1
- 125000004786 difluoromethoxy group Chemical group [H]C(F)(F)O* 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 230000006806 disease prevention Effects 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- YSMUFEAIAAOFHE-UHFFFAOYSA-N ethyl 3-[3-[[2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]-3-methylbutyl]benzimidazole-5-carboxylate Chemical compound C12=CC(C(=O)OCC)=CC=C2N=CN1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 YSMUFEAIAAOFHE-UHFFFAOYSA-N 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 150000004677 hydrates Chemical class 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- RNEXJMZCXHSHIZ-VWLOTQADSA-N n-[3-[(1r)-2-[[4-[5-(hydrazinecarbonyl)benzimidazol-1-yl]-2-methylbutan-2-yl]amino]-1-hydroxyethyl]phenyl]benzenesulfonamide Chemical compound C=1C([C@@H](O)CNC(C)(CCN2C3=CC=C(C=C3N=C2)C(=O)NN)C)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 RNEXJMZCXHSHIZ-VWLOTQADSA-N 0.000 claims 1
- RNEXJMZCXHSHIZ-UHFFFAOYSA-N n-[3-[2-[[4-[5-(hydrazinecarbonyl)benzimidazol-1-yl]-2-methylbutan-2-yl]amino]-1-hydroxyethyl]phenyl]benzenesulfonamide Chemical compound C1=NC2=CC(C(=O)NN)=CC=C2N1CCC(C)(C)NCC(O)C(C=1)=CC=CC=1NS(=O)(=O)C1=CC=CC=C1 RNEXJMZCXHSHIZ-UHFFFAOYSA-N 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 229940002612 prodrug Drugs 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
- 0 CS(Nc1cccc([C@@](CNC(*)(*)CC*)O)c1)(=O)=O Chemical compound CS(Nc1cccc([C@@](CNC(*)(*)CC*)O)c1)(=O)=O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005052102A DE102005052102A1 (de) | 2005-10-28 | 2005-10-28 | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| PCT/EP2006/067874 WO2007048842A1 (de) | 2005-10-28 | 2006-10-27 | Benzimidazolderivate als beta-3 rezeptor-agonisten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009513606A JP2009513606A (ja) | 2009-04-02 |
| JP2009513606A5 true JP2009513606A5 (https=) | 2009-12-17 |
Family
ID=37499975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008537112A Pending JP2009513606A (ja) | 2005-10-28 | 2006-10-27 | β−３受容体アゴニストとして使うためのベンゾイミダゾール誘導体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20070112033A1 (https=) |
| EP (1) | EP1943229A1 (https=) |
| JP (1) | JP2009513606A (https=) |
| AR (1) | AR058161A1 (https=) |
| CA (1) | CA2627090A1 (https=) |
| DE (1) | DE102005052102A1 (https=) |
| TW (1) | TW200800175A (https=) |
| WO (1) | WO2007048842A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004021779A1 (de) * | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102005052101A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102005052127A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| EP2298373A1 (de) | 2009-09-22 | 2011-03-23 | ECP Entwicklungsgesellschaft mbH | Fluidpumpe mit wenigstens einem Schaufelblatt und einer Stützeinrichtung |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2943090A (en) * | 1957-09-23 | 1960-06-28 | American Cyanamid Co | Substituted piperazines and method of preparing the same |
| US3092636A (en) * | 1959-10-21 | 1963-06-04 | Upjohn Co | Alpha-[2-(1-alkyleneimino) ethylamino]-alkanophenones and the corresponding alcohols |
| DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
| DE2833140A1 (de) * | 1978-07-28 | 1980-02-07 | Boehringer Sohn Ingelheim | Neue n-substituierte heterocyclen |
| GB9805520D0 (en) * | 1998-03-17 | 1998-05-13 | Zeneca Ltd | Chemical compounds |
| AU5257401A (en) * | 2000-04-28 | 2001-11-12 | Asahi Chemical Ind | Novel bicyclic compounds |
| DE60239170D1 (de) * | 2001-10-25 | 2011-03-24 | Asahi Kasei Pharma Corp | Bicyclische Verbindungen |
| DE10251170A1 (de) * | 2002-10-31 | 2004-05-13 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| US20040127733A1 (en) * | 2002-10-31 | 2004-07-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions |
| ATE479433T1 (de) * | 2004-02-14 | 2010-09-15 | Boehringer Ingelheim Int | Neue langwirksame beta-2-agonisten, und deren verwendung als arzneimittel |
| DE102004021779A1 (de) * | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102005052127A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
-
2005
- 2005-10-28 DE DE102005052102A patent/DE102005052102A1/de not_active Withdrawn
-
2006
- 2006-10-19 US US11/550,827 patent/US20070112033A1/en not_active Abandoned
- 2006-10-27 JP JP2008537112A patent/JP2009513606A/ja active Pending
- 2006-10-27 AR ARP060104695A patent/AR058161A1/es not_active Application Discontinuation
- 2006-10-27 WO PCT/EP2006/067874 patent/WO2007048842A1/de not_active Ceased
- 2006-10-27 EP EP06807621A patent/EP1943229A1/de not_active Withdrawn
- 2006-10-27 CA CA002627090A patent/CA2627090A1/en not_active Abandoned
- 2006-10-27 TW TW095139865A patent/TW200800175A/zh unknown
-
2007
- 2007-12-19 US US11/960,306 patent/US20080103138A1/en not_active Abandoned
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