JP2009512691A - クロストリジウムディフィシレ関連の下痢の治療方法 - Google Patents
クロストリジウムディフィシレ関連の下痢の治療方法 Download PDFInfo
- Publication number
- JP2009512691A JP2009512691A JP2008536608A JP2008536608A JP2009512691A JP 2009512691 A JP2009512691 A JP 2009512691A JP 2008536608 A JP2008536608 A JP 2008536608A JP 2008536608 A JP2008536608 A JP 2008536608A JP 2009512691 A JP2009512691 A JP 2009512691A
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- JP
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- Prior art keywords
- mixture
- compound
- weight
- treatment
- mcc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCC(CC(C)C(CC=CC=C(COC(C(C1O)OC)OC(C)C1OC(C(C(CC)=C(*(C)(C1Cl)O)Cl)=C1O)=O)C(O)OC(CC=C(C)C=C1C)C(C)=O)O)[C@]1OC(C(C1O)O)OC(C)(C)C1OC(C(C)C)=O Chemical compound CCC(CC(C)C(CC=CC=C(COC(C(C1O)OC)OC(C)C1OC(C(C(CC)=C(*(C)(C1Cl)O)Cl)=C1O)=O)C(O)OC(CC=C(C)C=C1C)C(C)=O)O)[C@]1OC(C(C1O)O)OC(C)(C)C1OC(C(C)C)=O 0.000 description 2
- TVNPCAPJKIVYOW-FBXMOKBDSA-N CCC(C(/C(/C)=C/C(/C)=C/CC(C(C)O)OC(/C(/COC(C(C1O)OC)OC(C)C1OC(c(c(C)c(c(O)c1Cl)Cl)c1O)=O)=C/C=C/C1)=O)OC(C(C2O)O)OC(C)(C)C2OC(C(C)C)=O)/C=C(\C)/C1O Chemical compound CCC(C(/C(/C)=C/C(/C)=C/CC(C(C)O)OC(/C(/COC(C(C1O)OC)OC(C)C1OC(c(c(C)c(c(O)c1Cl)Cl)c1O)=O)=C/C=C/C1)=O)OC(C(C2O)O)OC(C)(C)C2OC(C(C)C)=O)/C=C(\C)/C1O TVNPCAPJKIVYOW-FBXMOKBDSA-N 0.000 description 1
- IZMQFMVMOOINIK-LCDONECYSA-N CCC(C/C=C(\C)/C=C(\C)/C(C(CC)/C=C(\C)/C(C/C=C/C=C1\C)O)OC(C(C2O)O)OC(C)(C)C2OC(CC)=O)OC1=O Chemical compound CCC(C/C=C(\C)/C=C(\C)/C(C(CC)/C=C(\C)/C(C/C=C/C=C1\C)O)OC(C(C2O)O)OC(C)(C)C2OC(CC)=O)OC1=O IZMQFMVMOOINIK-LCDONECYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72913505P | 2005-10-21 | 2005-10-21 | |
US74964105P | 2005-12-12 | 2005-12-12 | |
PCT/US2006/041436 WO2007048059A2 (fr) | 2005-10-21 | 2006-10-23 | Méthode de traitement d'une diarrhée associée à clostridium difficile |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009512691A true JP2009512691A (ja) | 2009-03-26 |
JP2009512691A5 JP2009512691A5 (fr) | 2009-12-10 |
Family
ID=37963388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008536608A Pending JP2009512691A (ja) | 2005-10-21 | 2006-10-23 | クロストリジウムディフィシレ関連の下痢の治療方法 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1940417A4 (fr) |
JP (1) | JP2009512691A (fr) |
KR (1) | KR101399621B1 (fr) |
CN (2) | CN102503994A (fr) |
AU (1) | AU2006304868B2 (fr) |
CA (1) | CA2626698C (fr) |
HK (1) | HK1126410A1 (fr) |
WO (1) | WO2007048059A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7906489B2 (en) | 2004-05-14 | 2011-03-15 | Optimer Pharmaceuticals, Inc. | 18-membered macrocycles and analogs thereof |
US7378508B2 (en) | 2007-01-22 | 2008-05-27 | Optimer Pharmaceuticals, Inc. | Polymorphic crystalline forms of tiacumicin B |
TWI523654B (zh) | 2007-11-27 | 2016-03-01 | 默沙東藥廠 | 抗生素巨環化合物以及其製造及使用之方法 |
JO3464B1 (ar) | 2013-01-15 | 2020-07-05 | Astellas Pharma Europe Ltd | التركيبات الخاصة بمركبات التياكوميسين |
CN104846044B (zh) * | 2014-02-17 | 2019-02-01 | 上海医药工业研究院 | 一种提高非达霉素产量的发酵培养基 |
CN105237599B (zh) * | 2015-10-09 | 2018-10-02 | 华北制药集团新药研究开发有限责任公司 | 闰年霉素a4晶体及其制备方法 |
CN107970253B (zh) * | 2017-10-25 | 2020-05-26 | 中山大学 | 台勾霉素衍生物在制备治疗寨卡病毒感染引起的相关疾病和/或症状的药物中的应用 |
CN107714713B (zh) * | 2017-10-25 | 2020-05-26 | 中山大学 | 台勾霉素衍生物在制备治疗登革病毒感染引起的相关疾病和/或症状的药物中的应用 |
JP7397071B2 (ja) * | 2018-06-07 | 2023-12-12 | アルチュジェン セラピューティクス リミテッド | C.ディフィシル治療方法及び組成物 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004014295A2 (fr) * | 2002-07-29 | 2004-02-19 | Optimer Pharmaceuticals, Inc. | Fabrication de tiacumicine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4918174A (en) | 1986-09-26 | 1990-04-17 | Abbott Laboratories | Tiacumicin compounds |
US5583115A (en) * | 1995-05-09 | 1996-12-10 | Abbott Laboratories | Dialkyltiacumicin compounds |
SI2070530T1 (sl) * | 2004-05-14 | 2016-05-31 | Merck Sharp & Dohme Corp. | Zdravljenje bolezni, povezanih z uporabo antibiotikov |
MX2007009196A (es) * | 2005-01-31 | 2009-02-25 | Optimer Pharmaceuticals Inc | Compuestos macrocilicos de 18 miembros y analogos de los mismos. |
-
2006
- 2006-10-23 CA CA2626698A patent/CA2626698C/fr not_active Expired - Fee Related
- 2006-10-23 AU AU2006304868A patent/AU2006304868B2/en not_active Ceased
- 2006-10-23 KR KR1020087012193A patent/KR101399621B1/ko active IP Right Grant
- 2006-10-23 EP EP06826544A patent/EP1940417A4/fr not_active Withdrawn
- 2006-10-23 WO PCT/US2006/041436 patent/WO2007048059A2/fr active Application Filing
- 2006-10-23 CN CN2011103037682A patent/CN102503994A/zh active Pending
- 2006-10-23 JP JP2008536608A patent/JP2009512691A/ja active Pending
- 2006-10-23 CN CN2006800479861A patent/CN101340919B/zh not_active Expired - Fee Related
-
2009
- 2009-06-10 HK HK09105230.0A patent/HK1126410A1/xx not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004014295A2 (fr) * | 2002-07-29 | 2004-02-19 | Optimer Pharmaceuticals, Inc. | Fabrication de tiacumicine |
JP2005534332A (ja) * | 2002-07-29 | 2005-11-17 | オプティマー ファーマシューティカルズ、インコーポレイテッド | チアクマイシン生産 |
Non-Patent Citations (1)
Title |
---|
JPN6012028534; HOCHLOWSKI,J.E. et al: 'Tiacumicins, a novel complex of 18-membered macrolides. II. Isolation and structure determination' J Antibiot Vol.40, No.5, 1987, p.575-88 * |
Also Published As
Publication number | Publication date |
---|---|
EP1940417A2 (fr) | 2008-07-09 |
CN101340919B (zh) | 2011-12-07 |
AU2006304868B2 (en) | 2013-02-21 |
KR20080064177A (ko) | 2008-07-08 |
EP1940417A4 (fr) | 2010-07-07 |
HK1126410A1 (en) | 2009-09-04 |
AU2006304868A1 (en) | 2007-04-26 |
CA2626698A1 (fr) | 2007-04-26 |
CN102503994A (zh) | 2012-06-20 |
KR101399621B1 (ko) | 2014-06-18 |
CA2626698C (fr) | 2015-12-01 |
CN101340919A (zh) | 2009-01-07 |
WO2007048059A3 (fr) | 2007-05-31 |
WO2007048059A2 (fr) | 2007-04-26 |
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