JP2009510128A5 - - Google Patents

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Publication number
JP2009510128A5
JP2009510128A5 JP2008533791A JP2008533791A JP2009510128A5 JP 2009510128 A5 JP2009510128 A5 JP 2009510128A5 JP 2008533791 A JP2008533791 A JP 2008533791A JP 2008533791 A JP2008533791 A JP 2008533791A JP 2009510128 A5 JP2009510128 A5 JP 2009510128A5
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JP
Japan
Prior art keywords
carbon atoms
optionally substituted
compound
group
branched
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JP2008533791A
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English (en)
Japanese (ja)
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JP5322647B2 (ja
JP2009510128A (ja
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Priority claimed from PCT/US2006/038822 external-priority patent/WO2007041631A1/en
Publication of JP2009510128A publication Critical patent/JP2009510128A/ja
Publication of JP2009510128A5 publication Critical patent/JP2009510128A5/ja
Application granted granted Critical
Publication of JP5322647B2 publication Critical patent/JP5322647B2/ja
Expired - Fee Related legal-status Critical Current
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JP2008533791A 2005-09-30 2006-10-02 ウイルス感染の治療及び予防のためのシクロスポリンaのアリールアルキル及びヘテロアリールアルキル誘導体 Expired - Fee Related JP5322647B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72267805P 2005-09-30 2005-09-30
US60/722,678 2005-09-30
PCT/US2006/038822 WO2007041631A1 (en) 2005-09-30 2006-10-02 ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION

Publications (3)

Publication Number Publication Date
JP2009510128A JP2009510128A (ja) 2009-03-12
JP2009510128A5 true JP2009510128A5 (OSRAM) 2009-11-19
JP5322647B2 JP5322647B2 (ja) 2013-10-23

Family

ID=37561742

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008533791A Expired - Fee Related JP5322647B2 (ja) 2005-09-30 2006-10-02 ウイルス感染の治療及び予防のためのシクロスポリンaのアリールアルキル及びヘテロアリールアルキル誘導体

Country Status (8)

Country Link
US (1) US8329658B2 (OSRAM)
EP (1) EP1931696B1 (OSRAM)
JP (1) JP5322647B2 (OSRAM)
CN (1) CN101316859A (OSRAM)
AT (1) ATE498630T1 (OSRAM)
CA (1) CA2623864C (OSRAM)
DE (1) DE602006020152D1 (OSRAM)
WO (1) WO2007041631A1 (OSRAM)

Families Citing this family (25)

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US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
EP1931696B1 (en) 2005-09-30 2011-02-16 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection
CA2623865A1 (en) * 2005-09-30 2007-04-12 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection
AU2007254148B2 (en) 2006-05-19 2013-02-07 Scynexis, Inc. Method for the treatment and prevention of ocular disorders
KR101089112B1 (ko) * 2006-06-02 2011-12-06 피씨 제스띠옹 에스.아.에스. 활성 전자 관리
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
CN102083852A (zh) * 2008-06-06 2011-06-01 西尼克斯公司 环孢菌素类似物及其在治疗hcv感染中的应用
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
JP5780969B2 (ja) 2008-12-31 2015-09-16 サイネクシス,インコーポレーテッド シクロスポリンaの誘導体
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US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
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US20120010131A1 (en) 2009-12-30 2012-01-12 Scynexis, Inc. Novel cyclosporin analogues
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
KR102011339B1 (ko) 2010-12-15 2019-08-16 콘트라빌 파마슈티컬스, 인코퍼레이티드 아미노산 1 및 3에서 변형된 사이클로스포린 유사체 분자
US20140212381A1 (en) * 2012-10-19 2014-07-31 Scynexis, Inc. Macrocycles
WO2014085623A1 (en) 2012-11-28 2014-06-05 Enanta Pharmaceuticals, Inc. Novel [n-me-4-hydroxyleucine]-9-cyclosporin analogues
SG11201601274QA (en) 2013-08-26 2016-03-30 Enanta Pharm Inc Cyclosporin analogues for preventing or treating hepatitis c
WO2016073480A1 (en) 2014-11-03 2016-05-12 Enanta Pharmaceuticals, Inc. Novel cyclosporin analogues for preventing or treating hepatitis c infection
US10738084B2 (en) * 2015-06-30 2020-08-11 Sentry Therapeutics Limited Macrocycles
TW202502801A (zh) * 2023-06-02 2025-01-16 大陸商睿諾醫療科技(上海)有限公司 親環蛋白抑制劑及其用途

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EP1931696B1 (en) 2005-09-30 2011-02-16 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection
CA2623865A1 (en) * 2005-09-30 2007-04-12 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection
AU2007254148B2 (en) * 2006-05-19 2013-02-07 Scynexis, Inc. Method for the treatment and prevention of ocular disorders
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
WO2008127613A1 (en) 2007-04-11 2008-10-23 Scynexis, Inc. New pharmaceutical compositions
WO2008143996A1 (en) 2007-05-18 2008-11-27 Scynexis, Inc. New chemical processes
CN102083852A (zh) 2008-06-06 2011-06-01 西尼克斯公司 环孢菌素类似物及其在治疗hcv感染中的应用
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
JP5780969B2 (ja) * 2008-12-31 2015-09-16 サイネクシス,インコーポレーテッド シクロスポリンaの誘導体
CA2750227A1 (en) * 2009-01-07 2010-07-15 Scynexis, Inc. Cyclosporine derivative for use in the treatment of hcv and hiv infection
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US20110144005A1 (en) * 2009-12-09 2011-06-16 Scynexis, Inc. Novel cyclic peptides

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