JP2009505076A5 - - Google Patents

Download PDF

Info

Publication number
JP2009505076A5
JP2009505076A5 JP2008526232A JP2008526232A JP2009505076A5 JP 2009505076 A5 JP2009505076 A5 JP 2009505076A5 JP 2008526232 A JP2008526232 A JP 2008526232A JP 2008526232 A JP2008526232 A JP 2008526232A JP 2009505076 A5 JP2009505076 A5 JP 2009505076A5
Authority
JP
Japan
Prior art keywords
optical
optical signals
signal
different
constrained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008526232A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009505076A (ja
Filing date
Publication date
Priority claimed from US11/201,768 external-priority patent/US7805081B2/en
Application filed filed Critical
Publication of JP2009505076A publication Critical patent/JP2009505076A/ja
Publication of JP2009505076A5 publication Critical patent/JP2009505076A5/ja
Pending legal-status Critical Current

Links

JP2008526232A 2005-08-11 2006-08-10 単一信号源からの複数の光信号をモニターするための方法及びシステム Pending JP2009505076A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/201,768 US7805081B2 (en) 2005-08-11 2005-08-11 Methods and systems for monitoring multiple optical signals from a single source
PCT/US2006/031387 WO2007019582A2 (en) 2005-08-11 2006-08-10 Methods and systems for monitoring multiple optical signals from a single source

Publications (2)

Publication Number Publication Date
JP2009505076A JP2009505076A (ja) 2009-02-05
JP2009505076A5 true JP2009505076A5 (enExample) 2009-10-01

Family

ID=37728043

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008526232A Pending JP2009505076A (ja) 2005-08-11 2006-08-10 単一信号源からの複数の光信号をモニターするための方法及びシステム

Country Status (7)

Country Link
US (3) US7805081B2 (enExample)
EP (1) EP1920277A4 (enExample)
JP (1) JP2009505076A (enExample)
CN (1) CN101536368A (enExample)
AU (1) AU2006278236B2 (enExample)
CA (1) CA2616439C (enExample)
WO (1) WO2007019582A2 (enExample)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7805081B2 (en) * 2005-08-11 2010-09-28 Pacific Biosciences Of California, Inc. Methods and systems for monitoring multiple optical signals from a single source
US7763423B2 (en) * 2005-09-30 2010-07-27 Pacific Biosciences Of California, Inc. Substrates having low density reactive groups for monitoring enzyme activity
CN101400492B (zh) * 2006-03-20 2012-07-25 三井化学株式会社 光学膜及其制造方法
US8975216B2 (en) * 2006-03-30 2015-03-10 Pacific Biosciences Of California Articles having localized molecules disposed thereon and methods of producing same
US20080050747A1 (en) * 2006-03-30 2008-02-28 Pacific Biosciences Of California, Inc. Articles having localized molecules disposed thereon and methods of producing and using same
CA2662521C (en) * 2006-09-01 2016-08-09 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US8207509B2 (en) 2006-09-01 2012-06-26 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US20100167413A1 (en) * 2007-05-10 2010-07-01 Paul Lundquist Methods and systems for analyzing fluorescent materials with reduced autofluorescence
US20080277595A1 (en) * 2007-05-10 2008-11-13 Pacific Biosciences Of California, Inc. Highly multiplexed confocal detection systems and methods of using same
US8703422B2 (en) 2007-06-06 2014-04-22 Pacific Biosciences Of California, Inc. Methods and processes for calling bases in sequence by incorporation methods
CA2689626C (en) * 2007-06-06 2016-10-25 Pacific Biosciences Of California, Inc. Methods and processes for calling bases in sequence by incorporation methods
US8517990B2 (en) 2007-12-18 2013-08-27 Hospira, Inc. User interface improvements for medical devices
WO2009089056A1 (en) * 2008-01-10 2009-07-16 Pacific Biosciences Of California, Inc. Methods and systems for analysis of fluorescent reactions with modulated excitation
AU2009212165A1 (en) 2008-02-07 2009-08-13 Pacific Biosciences Of California, Inc. CIS reactive oxygen quenchers integrated into linkers
US8652781B2 (en) 2008-02-12 2014-02-18 Pacific Biosciences Of California, Inc. Cognate sampling kinetics
WO2009102470A2 (en) * 2008-02-12 2009-08-20 Pacific Biosciences Of California, Inc. Compositions and methods for use in analytical reactions
US7968702B2 (en) 2008-03-13 2011-06-28 Pacific Biosciences Of California, Inc. Labeled reactants and their uses
US20090229651A1 (en) * 2008-03-14 2009-09-17 Fay Jr Theodore Denis Solar energy production system
US7973146B2 (en) * 2008-03-26 2011-07-05 Pacific Biosciences Of California, Inc. Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing
US8143030B2 (en) 2008-09-24 2012-03-27 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
WO2009145828A2 (en) * 2008-03-31 2009-12-03 Pacific Biosciences Of California, Inc. Two slow-step polymerase enzyme systems and methods
AU2009251883B2 (en) * 2008-03-31 2014-09-11 Pacific Biosciences Of California, Inc. Generation of modified polymerases for improved accuracy in single molecule sequencing
US8420366B2 (en) * 2008-03-31 2013-04-16 Pacific Biosciences Of California, Inc. Generation of modified polymerases for improved accuracy in single molecule sequencing
US8999676B2 (en) 2008-03-31 2015-04-07 Pacific Biosciences Of California, Inc. Recombinant polymerases for improved single molecule sequencing
EP2279268A4 (en) 2008-04-04 2011-12-07 Life Technologies Corp SCANNING SYSTEM AND METHOD OF IMAGING AND SEQUENCING
CA2735979A1 (en) * 2008-09-05 2010-03-11 Pacific Biosciences Of California, Inc. Engineering polymerases and reaction conditions for modified incorporation properties
CA2974241C (en) 2008-09-16 2020-01-07 Pacific Biosciences Of California, Inc. Substrates and optical systems and methods of use thereof
EP2370598B1 (en) 2008-12-11 2017-02-15 Pacific Biosciences Of California, Inc. Classification of nucleic acid templates
WO2010096890A1 (en) * 2009-02-25 2010-09-02 Synergx Technologies Inc. Optical structure and optical system for providing concurrent optical images of an object
US9778188B2 (en) * 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
US8501406B1 (en) 2009-07-14 2013-08-06 Pacific Biosciences Of California, Inc. Selectively functionalized arrays
WO2011019713A1 (en) * 2009-08-11 2011-02-17 Wedge Technologies Ultra dark field microscope
US8772016B2 (en) 2009-11-13 2014-07-08 Pacific Biosciences Of California, Inc. Sealed chip package
EP2537053B1 (en) 2010-02-19 2016-11-02 Pacific Biosciences of California, Inc. An analytical device comprising an optode array chip
US8994946B2 (en) 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
US9482615B2 (en) * 2010-03-15 2016-11-01 Industrial Technology Research Institute Single-molecule detection system and methods
PT2556171E (pt) 2010-04-05 2015-12-21 Prognosys Biosciences Inc Ensaios biológicos codificados espacialmente
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US9670243B2 (en) 2010-06-02 2017-06-06 Industrial Technology Research Institute Compositions and methods for sequencing nucleic acids
US8865078B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
US8865077B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
WO2012009206A2 (en) 2010-07-12 2012-01-19 Pacific Biosciences Of California, Inc. Sequencing reactions with alkali metal cations for pulse width control
US8993737B2 (en) 2010-08-25 2015-03-31 Pacific Biosciences, Inc. Phospholinked dye analogs with an amino acid linker
SG191409A1 (en) 2010-12-27 2013-08-30 Ibis Biosciences Inc Nucleic acid sample preparation methods and compositions
EP3150750B1 (en) 2011-04-08 2018-12-26 Prognosys Biosciences, Inc. Peptide constructs and assay systems
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US9670538B2 (en) 2011-08-05 2017-06-06 Ibis Biosciences, Inc. Nucleic acid sequencing by electrochemical detection
CA2844807C (en) 2011-08-19 2022-07-26 Hospira, Inc. Systems and methods for a graphical interface including a graphical representation of medical data
US9267917B2 (en) 2011-11-04 2016-02-23 Pacific Biosciences Of California, Inc. Nanopores in zero mode waveguides
WO2013090709A1 (en) 2011-12-16 2013-06-20 Hospira, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
WO2013101743A2 (en) 2011-12-30 2013-07-04 Abbott Molecular, Inc. Microorganism nucelic acid purification from host samples
WO2013106737A1 (en) 2012-01-13 2013-07-18 Data2Bio Genotyping by next-generation sequencing
EP3222627B1 (en) 2012-02-15 2019-08-07 Pacific Biosciences of California, Inc. Polymerase enzyme substrates with protein shield
AU2013240166A1 (en) 2012-03-30 2014-10-30 Pacific Biosciences Of California, Inc. Methods and composition for sequencing modified nucleic acids
ES2741725T3 (es) 2012-03-30 2020-02-12 Icu Medical Inc Sistema de detección de aire y método para detectar aire en una bomba de un sistema de infusión
ES2683707T3 (es) 2012-05-02 2018-09-27 Ibis Biosciences, Inc. Secuenciación de ADN
EP3789502A1 (en) 2012-05-02 2021-03-10 Ibis Biosciences, Inc. Dna sequencing
WO2013166304A1 (en) 2012-05-02 2013-11-07 Ibis Biosciences, Inc. Dna sequencing
US9315864B2 (en) 2012-05-18 2016-04-19 Pacific Biosciences Of California, Inc. Heteroarylcyanine dyes with sulfonic acid substituents
EP2850086B1 (en) 2012-05-18 2023-07-05 Pacific Biosciences Of California, Inc. Heteroarylcyanine dyes
WO2013185137A1 (en) 2012-06-08 2013-12-12 Pacific Biosciences Of California, Inc. Modified base detection with nanopore sequencing
US9551030B2 (en) 2012-06-17 2017-01-24 Pacific Biosciences Of California, Inc. Filter architecture for analytical devices
US9372308B1 (en) 2012-06-17 2016-06-21 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices and methods for production
DE102012221356A1 (de) * 2012-06-20 2013-12-24 Robert Bosch Gmbh Sensor und Verfahren zur Erfassung von Licht und Verfahren und Vorrichtung zur Ermittlung einer Farbinformation
US10463788B2 (en) 2012-07-31 2019-11-05 Icu Medical, Inc. Patient care system for critical medications
US9399766B2 (en) 2012-10-01 2016-07-26 Pacific Biosciences Of California, Inc. Recombinant polymerases for incorporation of protein shield nucleotide analogs
WO2014062835A1 (en) 2012-10-16 2014-04-24 Abbott Molecular Inc. Methods and apparatus to sequence a nucleic acid
DK3511423T4 (da) 2012-10-17 2024-07-29 Spatial Transcriptomics Ab Fremgangsmåder og produkt til optimering af lokaliseret eller rumlig detektion af genekspression i en vævsprøve
EP3734255B1 (en) 2012-12-18 2022-10-19 Pacific Biosciences Of California, Inc. An optical analytical device
WO2014130900A1 (en) 2013-02-22 2014-08-28 Pacific Biosciences Of California, Inc. Integrated illumination of optical analytical devices
CA2913421C (en) 2013-05-24 2022-02-15 Hospira, Inc. Multi-sensor infusion system for detecting air or an occlusion in the infusion system
AU2014274146B2 (en) 2013-05-29 2019-01-24 Icu Medical, Inc. Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system
US9707341B2 (en) 2013-05-29 2017-07-18 Icu Medical, Inc. Infusion system and method of use which prevents over-saturation of an analog-to-digital converter
WO2014194028A1 (en) 2013-05-31 2014-12-04 Pacific Biosciences Of California, Inc Analytical devices having compact lens train arrays
EP4234716A3 (en) 2013-06-25 2023-12-06 Prognosys Biosciences, Inc. Methods for determining spatial patterns of biological targets in a sample
US20150051088A1 (en) 2013-08-19 2015-02-19 Abbott Molecular Inc. Next-generation sequencing libraries
EP3049539B1 (en) 2013-09-25 2018-09-05 Bio-Id Diagnostic Inc. Methods for detecting nucleic acid fragments
CN104518835B (zh) * 2013-10-08 2019-07-23 中兴通讯股份有限公司 一种可见光通信mimo系统的接收装置
US9349260B2 (en) * 2013-11-13 2016-05-24 Rockwell Automation Technologies, Inc. Sensor device with enhanced light guide visualization and related methods
EP3083700B1 (en) 2013-12-17 2023-10-11 The Brigham and Women's Hospital, Inc. Detection of an antibody against a pathogen
US12183436B2 (en) 2013-12-18 2024-12-31 Pacific Biosciences Of California, Inc. String graph assembly for polyploid genomes
AU2015222800B2 (en) 2014-02-28 2019-10-17 Icu Medical, Inc. Infusion system and method which utilizes dual wavelength optical air-in-line detection
US9723386B1 (en) * 2014-05-05 2017-08-01 Google Inc. Communication device
JP2017517302A (ja) 2014-05-29 2017-06-29 ホスピーラ インコーポレイテッド 構成可能閉ループ送達速度キャッチアップを有する注入システムおよびポンプ
CN114214314A (zh) 2014-06-24 2022-03-22 生物辐射实验室股份有限公司 数字式pcr条码化
EP3594684A1 (en) 2014-06-27 2020-01-15 Abbott Laboratories Compositions and methods for detecting human pegivirus 2 (hpgv-2)
JP6415893B2 (ja) * 2014-08-05 2018-10-31 キヤノンメディカルシステムズ株式会社 検体測定装置及び検体測定方法
CN107003241B (zh) 2014-08-27 2022-01-11 加利福尼亚太平洋生物科学股份有限公司 集成分析器件阵列
ES2788692T3 (es) 2014-09-17 2020-10-22 Ibis Biosciences Inc Secuenciación por síntesis usando óptica de lectura por pulsos
US11344668B2 (en) 2014-12-19 2022-05-31 Icu Medical, Inc. Infusion system with concurrent TPN/insulin infusion
US10302972B2 (en) 2015-01-23 2019-05-28 Pacific Biosciences Of California, Inc. Waveguide transmission
US10850024B2 (en) 2015-03-02 2020-12-01 Icu Medical, Inc. Infusion system, device, and method having advanced infusion features
EP4220256A1 (en) 2015-03-16 2023-08-02 Pacific Biosciences of California, Inc. Analytical system comprising integrated devices and systems for free-space optical coupling
WO2016154345A1 (en) 2015-03-24 2016-09-29 Pacific Biosciences Of California, Inc. Methods and compositions for single molecule composition loading
EP4119677B1 (en) 2015-04-10 2023-06-28 Spatial Transcriptomics AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
EP3286549A4 (en) * 2015-04-22 2019-04-17 Shenzhen Genorivision Technology Co., Ltd. BIOSENSOR
AU2016259012C1 (en) 2015-05-07 2022-11-17 Pacific Biosciences Of California, Inc. Multiprocessor pipeline architecture
CN107615283B (zh) 2015-05-26 2022-07-05 加利福尼亚太平洋生物科学股份有限公司 用于二倍体基因组组装和单倍型序列重建的方法、软件和系统
EP4425153A3 (en) 2015-06-12 2024-11-20 Pacific Biosciences Of California, Inc. Integrated target waveguide devices and systems for optical coupling
WO2017087696A1 (en) 2015-11-18 2017-05-26 Pacific Biosciences Of California, Inc. Methods and compositions for loading of polymerase complexes
CN108350487B (zh) 2015-11-19 2022-05-27 加利福尼亚太平洋生物科学股份有限公司 用于改善信号检测的化合物和系统
EP3400298B1 (en) 2016-01-08 2024-03-06 Bio-Rad Laboratories, Inc. Multiple beads per droplet resolution
WO2017197024A1 (en) 2016-05-13 2017-11-16 Icu Medical, Inc. Infusion pump system and method with common line auto flush
WO2017214441A1 (en) 2016-06-10 2017-12-14 Icu Medical, Inc. Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion
US10544457B2 (en) 2016-06-14 2020-01-28 Pacific Biosciences Of California, Inc. Methods and compositions for enriching compositions for polymerase enzyme complexes
US10711300B2 (en) 2016-07-22 2020-07-14 Pacific Biosciences Of California, Inc. Methods and compositions for delivery of molecules and complexes to reaction sites
WO2018042251A1 (en) 2016-08-29 2018-03-08 Oslo Universitetssykehus Hf Chip-seq assays
CN110139932B (zh) 2016-12-19 2024-05-17 生物辐射实验室股份有限公司 液滴加标的相邻性保留的标签化dna
US11186862B2 (en) 2017-06-20 2021-11-30 Bio-Rad Laboratories, Inc. MDA using bead oligonucleotide
US11162138B2 (en) 2017-10-30 2021-11-02 Pacific Biosciences Of California, Inc. Multi-amplitude modular labeled compounds
CN118186055A (zh) 2017-11-02 2024-06-14 生物辐射实验室股份有限公司 基于转座酶的基因组分析
US10655168B2 (en) 2017-12-22 2020-05-19 Pacific Biosciences Of California, Inc. Modified biotin-binding proteins for immobilization
US10089055B1 (en) 2017-12-27 2018-10-02 Icu Medical, Inc. Synchronized display of screen content on networked devices
EP4324962A3 (en) 2018-01-31 2024-05-08 Bio-Rad Laboratories, Inc. Methods and compositions for deconvoluting partition barcodes
US12054772B2 (en) 2018-03-13 2024-08-06 Sarmal, Inc. Methods for single molecule sequencing
US11512002B2 (en) 2018-04-18 2022-11-29 University Of Virginia Patent Foundation Silica materials and methods of making thereof
WO2020006421A1 (en) 2018-06-29 2020-01-02 Pacific Biosciences Of California, Inc. Methods and compositions for delivery of molecules and complexes to reaction sites
US11479816B2 (en) 2018-08-20 2022-10-25 Bio-Rad Laboratories, Inc. Nucleotide sequence generation by barcode bead-colocalization in partitions
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
US11278671B2 (en) 2019-12-04 2022-03-22 Icu Medical, Inc. Infusion pump with safety sequence keypad
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
WO2021152586A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Methods of analyzing microbiome, immunoglobulin profile and physiological state
WO2021186739A1 (ja) * 2020-03-19 2021-09-23 ギガフォトン株式会社 狭帯域化装置、及び電子デバイスの製造方法
WO2021214766A1 (en) 2020-04-21 2021-10-28 Yeda Research And Development Co. Ltd. Methods of diagnosing viral infections and vaccines thereto
EP4153984A1 (en) 2020-05-19 2023-03-29 10X Genomics, Inc. Electrophoresis cassettes and instrumentation
WO2021236929A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
AU2021311443A1 (en) 2020-07-21 2023-03-09 Icu Medical, Inc. Fluid transfer devices and methods of use
ES2993269T3 (en) 2020-09-18 2024-12-26 10X Genomics Inc Sample handling apparatus and image registration methods
US11476933B1 (en) * 2020-09-24 2022-10-18 SA Photonics, Inc. Free space optical communication terminal with rotatable dispersive optical component
US11135360B1 (en) 2020-12-07 2021-10-05 Icu Medical, Inc. Concurrent infusion with common line auto flush
ES2989523T3 (es) 2021-02-19 2024-11-26 10X Genomics Inc Método de uso de un dispositivo modular de soporte para ensayos
EP4089401B1 (de) * 2021-05-10 2024-11-06 Siemens Aktiengesellschaft Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz
USD1064308S1 (en) 2021-09-17 2025-02-25 10X Genomics, Inc. Sample handling device
USD1091564S1 (en) 2021-10-13 2025-09-02 Icu Medical, Inc. Display screen or portion thereof with graphical user interface for a medical device
CA3241894A1 (en) 2021-12-10 2023-06-15 Icu Medical, Inc. Medical fluid compounding systems with coordinated flow control
EP4441711A1 (en) 2021-12-20 2024-10-09 10X Genomics, Inc. Self-test for pathology/histology slide imaging device
CN120693504A (zh) * 2023-02-27 2025-09-23 松下知识产权经营株式会社 摄像装置、光学部件及测定系统

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
US4626684A (en) * 1983-07-13 1986-12-02 Landa Isaac J Rapid and automatic fluorescence immunoassay analyzer for multiple micro-samples
US5821058A (en) 1984-01-16 1998-10-13 California Institute Of Technology Automated DNA sequencing technique
US4648712A (en) * 1985-02-04 1987-03-10 Champion International Corporation Apparatus and method for analyzing parameters of a fibrous substrate
US6919211B1 (en) * 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
WO1991006678A1 (en) 1989-10-26 1991-05-16 Sri International Dna sequencing
US5239178A (en) * 1990-11-10 1993-08-24 Carl Zeiss Optical device with an illuminating grid and detector grid arranged confocally to an object
US5677196A (en) * 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
US5470710A (en) * 1993-10-22 1995-11-28 University Of Utah Automated hybridization/imaging device for fluorescent multiplex DNA sequencing
US5491344A (en) * 1993-12-01 1996-02-13 Tufts University Method and system for examining the composition of a fluid or solid sample using fluorescence and/or absorption spectroscopy
US5578832A (en) * 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5631734A (en) * 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5695934A (en) * 1994-10-13 1997-12-09 Lynx Therapeutics, Inc. Massively parallel sequencing of sorted polynucleotides
WO1996027025A1 (en) 1995-02-27 1996-09-06 Ely Michael Rabani Device, compounds, algorithms, and methods of molecular characterization and manipulation with molecular parallelism
US6017434A (en) * 1995-05-09 2000-01-25 Curagen Corporation Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments
US5545531A (en) * 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
JP2935661B2 (ja) * 1996-04-09 1999-08-16 株式会社日立製作所 蛍光検出型電気泳動装置における蛍光検出方法
US5776785A (en) * 1996-12-30 1998-07-07 Diagnostic Products Corporation Method and apparatus for immunoassay using fluorescent induced surface plasma emission
US5828452A (en) * 1996-12-31 1998-10-27 Dakota Technologies, Inc. Spectroscopic system with a single converter and method for removing overlap in time of detected emissions
AU756945B2 (en) * 1997-05-23 2003-01-30 Bioarray Solutions Ltd Color-encoding and in-situ interrogation of matrix-coupled chemical compounds
US6071748A (en) * 1997-07-16 2000-06-06 Ljl Biosystems, Inc. Light detection device
CA2294962C (en) * 1997-07-28 2012-09-18 Medical Biosystems Ltd. Nucleic acid sequence analysis
GB9727355D0 (en) * 1997-12-24 1998-02-25 Kalibrant Limited A composition for use in fluorescence assay systems
US6388788B1 (en) * 1998-03-16 2002-05-14 Praelux, Inc. Method and apparatus for screening chemical compounds
AU3970799A (en) * 1998-05-04 1999-11-23 Board Of Regents Combined fluorescence and reflectance spectroscopy
EP1105529B2 (en) 1998-07-30 2013-05-29 Illumina Cambridge Limited Arrayed biomolecules and their use in sequencing
US6263286B1 (en) * 1998-08-13 2001-07-17 U.S. Genomics, Inc. Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer
US6210896B1 (en) * 1998-08-13 2001-04-03 Us Genomics Molecular motors
AU749690B2 (en) * 1998-08-21 2002-07-04 Surromed, Inc. Novel optical architectures for microvolume laser-scanning cytometers
JP3335314B2 (ja) * 1998-10-29 2002-10-15 インターナショナル・ビジネス・マシーンズ・コーポレーション データ記録装置及びこれの制御方法
US6232075B1 (en) 1998-12-14 2001-05-15 Li-Cor, Inc. Heterogeneous assay for pyrophosphate detection
US6632655B1 (en) 1999-02-23 2003-10-14 Caliper Technologies Corp. Manipulation of microparticles in microfluidic systems
GB9906929D0 (en) * 1999-03-26 1999-05-19 Univ Glasgow Assay system
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US6287774B1 (en) * 1999-05-21 2001-09-11 Caliper Technologies Corp. Assay methods and system
EP1055925B1 (en) * 1999-05-28 2010-09-08 Yokogawa Electric Corporation Biochip reader
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7209836B1 (en) * 1999-07-16 2007-04-24 Perkinelmer Las, Inc. Method and system for automatically creating crosstalk-corrected data of a microarray
WO2001016375A2 (en) 1999-08-30 2001-03-08 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
US6982146B1 (en) 1999-08-30 2006-01-03 The United States Of America As Represented By The Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
US6784982B1 (en) * 1999-11-04 2004-08-31 Regents Of The University Of Minnesota Direct mapping of DNA chips to detector arrays
JP2001311690A (ja) * 2000-04-28 2001-11-09 Yokogawa Electric Corp バイオチップ読取装置及び電気泳動装置
US6690467B1 (en) 2000-05-05 2004-02-10 Pe Corporation Optical system and method for optically analyzing light from a sample
US6917726B2 (en) * 2001-09-27 2005-07-12 Cornell Research Foundation, Inc. Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes
US20060008799A1 (en) * 2000-05-22 2006-01-12 Hong Cai Rapid haplotyping by single molecule detection
US6869764B2 (en) 2000-06-07 2005-03-22 L--Cor, Inc. Nucleic acid sequencing using charge-switch nucleotides
GB0016473D0 (en) 2000-07-05 2000-08-23 Amersham Pharm Biotech Uk Ltd Sequencing method
GB0016472D0 (en) 2000-07-05 2000-08-23 Amersham Pharm Biotech Uk Ltd Sequencing method and apparatus
JP2002050778A (ja) 2000-08-02 2002-02-15 Nippon Sheet Glass Co Ltd 受光素子アレイおよびそれを用いた光通信モニタモジュール
US20070196815A1 (en) * 2000-08-02 2007-08-23 Jason Lappe Positive Selection Procedure for Optically Directed Selection of Cells
US6545758B1 (en) * 2000-08-17 2003-04-08 Perry Sandstrom Microarray detector and synthesizer
US6718395B1 (en) * 2000-10-10 2004-04-06 Computer Access Technology Corporation Apparatus and method using an inquiry response for synchronizing to a communication network
FR2824139B1 (fr) * 2001-04-27 2003-05-30 Commissariat Energie Atomique Dispositif de mesure de luminescence a elimintation d'effet de prefiltre
US7052839B2 (en) 2001-08-29 2006-05-30 Amersham Biosciences Corp Terminal-phosphate-labeled nucleotides and methods of use
US7244566B2 (en) 2001-08-29 2007-07-17 Ge Healthcare Bio-Sciences Corp. Analyte detection
US7560254B2 (en) 2001-08-29 2009-07-14 Ge Healthcare Bio-Sciences Corp. Allele specific primer extension
US7033762B2 (en) 2001-08-29 2006-04-25 Amersham Biosciences Corp Single nucleotide amplification and detection by polymerase
US7189361B2 (en) 2001-12-19 2007-03-13 3M Innovative Properties Company Analytical device with lightguide Illumination of capillary and microgrooves arrays
DE10200499A1 (de) * 2002-01-03 2003-07-10 Zeiss Carl Jena Gmbh Verfahren und/oder Anordnung zur Identifikation von fluoreszierenden, lumineszierenden und/oder absorbierenden Substanzen auf und/oder in Probenträgern
JP4209623B2 (ja) * 2002-03-19 2009-01-14 株式会社日立ハイテクノロジーズ 核酸塩基配列決定方法
ES2306866T5 (es) * 2002-03-20 2012-11-29 Rollease, Inc. Un embrague de toldo de rodillo con engranaje interno
JP4377811B2 (ja) * 2002-06-21 2009-12-02 オリンパス株式会社 生体分子解析装置および生体分子解析方法
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
CA2536969C (en) 2003-05-05 2009-09-29 D4D Technologies, L.P. Optical coherence tomography imaging
FI20030867A7 (fi) 2003-06-10 2004-12-11 Wallac Oy Optinen mittausmenetelmä ja laboratoriomittauslaite
JP4331521B2 (ja) * 2003-06-25 2009-09-16 富士フイルム株式会社 標的検出装置及び標的検出方法、並びに、標的検出試薬
US7075059B2 (en) 2003-09-11 2006-07-11 Applera Corporation Image enhancement by sub-pixel imaging
US7323681B1 (en) 2003-09-11 2008-01-29 Applera Corporation Image enhancement by sub-pixel imaging
US7233393B2 (en) 2004-08-05 2007-06-19 Applera Corporation Signal noise reduction for imaging in biological analysis
US20050135974A1 (en) 2003-12-18 2005-06-23 Harvey Michael A. Device for preparing multiple assay samples using multiple array surfaces
US7302348B2 (en) * 2004-06-02 2007-11-27 Agilent Technologies, Inc. Method and system for quantifying and removing spatial-intensity trends in microarray data
US20070048748A1 (en) * 2004-09-24 2007-03-01 Li-Cor, Inc. Mutant polymerases for sequencing and genotyping
US7130041B2 (en) 2005-03-02 2006-10-31 Li-Cor, Inc. On-chip spectral filtering using CCD array for imaging and spectroscopy
WO2006116726A2 (en) 2005-04-28 2006-11-02 Applera Corporation Multi-color light detection with imaging detectors
WO2006135782A2 (en) 2005-06-10 2006-12-21 Applera Corporation Method and system for multiplex genetic analysis
US20060291706A1 (en) 2005-06-23 2006-12-28 Applera Corporation Method of extracting intensity data from digitized image
US7227128B2 (en) 2005-06-30 2007-06-05 Applera Corporation System and methods for improving signal/noise ratio for signal detectors
WO2007011549A1 (en) 2005-06-30 2007-01-25 Applera Corporation Two-dimensional spectral imaging system
US20070099212A1 (en) * 2005-07-28 2007-05-03 Timothy Harris Consecutive base single molecule sequencing
US7805081B2 (en) * 2005-08-11 2010-09-28 Pacific Biosciences Of California, Inc. Methods and systems for monitoring multiple optical signals from a single source
EP2027442A2 (en) * 2006-05-16 2009-02-25 Applied Biosystems, Inc. Systems, methods, and apparatus for single molecule sequencing
WO2008002765A2 (en) 2006-06-27 2008-01-03 Applera Corporation Method and system for compensating for spatial cross-talk
US7803609B2 (en) 2006-07-21 2010-09-28 Affymetrix, Inc. System, method, and product for generating patterned illumination
CA2662521C (en) * 2006-09-01 2016-08-09 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials

Similar Documents

Publication Publication Date Title
JP2009505076A5 (enExample)
US20230417975A1 (en) Illumination of Optical Analytical Devices
CA2616439A1 (en) Methods and systems for monitoring multiple optical signals from a single source
AU2004254552B2 (en) Methods of amplifying and sequencing nucleic acids
US20070141598A1 (en) Nucleotide Compositions and Uses Thereof
US7767394B2 (en) Nucleotide compositions and uses thereof
GB2461026A (en) Optical scanning system for nucleic acids sequencing by phased synthesis
US20100152424A1 (en) Modular Nucleotide Compositions and Uses Therefor
TW200710381A (en) Heating element for a rotating multiplex fluorescence detection device
MX2007012158A (es) Dispositivo de deteccion de fluorescencia de transmision multiple que tiene modulos opticos multiples de acoplamiento a un haz de fibras para un detector comun.
TW200710394A (en) Valve control system for a rotating multiplex fluorescence detection device
CA2616762A1 (en) Methods of amplifying sequencing nucleic acids
US8993230B2 (en) Asynchronous sequencing of biological polymers
US11269199B2 (en) Producing bragg gratings in optical waveguides
TW202232084A (zh) 影像感測器結構及相關方法
TW200710382A (en) Multiplex fluorescence detection device having removable optical modules