JP2009503107A - スフィンゴシンキナーゼ阻害剤およびそれらの使用方法 - Google Patents
スフィンゴシンキナーゼ阻害剤およびそれらの使用方法 Download PDFInfo
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- JP2009503107A JP2009503107A JP2008525195A JP2008525195A JP2009503107A JP 2009503107 A JP2009503107 A JP 2009503107A JP 2008525195 A JP2008525195 A JP 2008525195A JP 2008525195 A JP2008525195 A JP 2008525195A JP 2009503107 A JP2009503107 A JP 2009503107A
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- Prior art keywords
- phenyl
- chloro
- alkyl
- thiazol
- thiazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 **c(cc1)ccc1-c1ccccc1 Chemical compound **c(cc1)ccc1-c1ccccc1 0.000 description 7
- QRMZSPFSDQBLIX-UHFFFAOYSA-N COc(cc(CC(O)=O)cc1)c1O Chemical compound COc(cc(CC(O)=O)cc1)c1O QRMZSPFSDQBLIX-UHFFFAOYSA-N 0.000 description 1
- OVHUVUNDPICMKU-UHFFFAOYSA-N OC(CC(C1)C=CC(O)=C1O)=O Chemical compound OC(CC(C1)C=CC(O)=C1O)=O OVHUVUNDPICMKU-UHFFFAOYSA-N 0.000 description 1
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- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/75—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
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- Organic Chemistry (AREA)
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- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
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- Neurosurgery (AREA)
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- Biomedical Technology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70560805P | 2005-08-04 | 2005-08-04 | |
| PCT/US2006/030327 WO2007019251A2 (en) | 2005-08-04 | 2006-08-03 | Sphingosine kinase inhibitors and methods of their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009503107A true JP2009503107A (ja) | 2009-01-29 |
| JP2009503107A5 JP2009503107A5 (https=) | 2009-09-17 |
Family
ID=37433959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008525195A Pending JP2009503107A (ja) | 2005-08-04 | 2006-08-03 | スフィンゴシンキナーゼ阻害剤およびそれらの使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20070032531A1 (https=) |
| EP (1) | EP1928848A2 (https=) |
| JP (1) | JP2009503107A (https=) |
| AU (1) | AU2006278592A1 (https=) |
| CA (1) | CA2617788A1 (https=) |
| IL (1) | IL188932A0 (https=) |
| WO (1) | WO2007019251A2 (https=) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013522310A (ja) * | 2010-03-17 | 2013-06-13 | タイヴェックス・セラピューティクス・インコーポレイテッド | Hec1活性の調節因子およびそのための方法 |
| JP2014526536A (ja) * | 2011-09-23 | 2014-10-06 | バイヤースドルフ・アクチエンゲゼルシヤフト | 芳香族アミドチアゾール、それを含有する化粧用または皮膚科用製剤、ならびに望ましくない皮膚の色素沈着を治療および予防するためのその使用 |
| JP2014526537A (ja) * | 2011-09-23 | 2014-10-06 | バイヤースドルフ・アクチエンゲゼルシヤフト | 複素環カルボニルアミノチアゾール、それを含有する化粧用または皮膚科用製剤、および望ましくない皮膚の色素沈着を治療・予防するためのその使用 |
| JP2017505295A (ja) * | 2013-12-19 | 2017-02-16 | バイエルスドルフ・アクチエンゲゼルシヤフトBeiersdorf AG | 敏感肌の予防及び治療のための、化粧品用又は皮膚用調製物におけるアルキルアミドチアゾールの使用 |
| JP2017526733A (ja) * | 2014-06-26 | 2017-09-14 | モナシュ ユニヴァーシティ | 酵素相互作用薬剤 |
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| JP2013522310A (ja) * | 2010-03-17 | 2013-06-13 | タイヴェックス・セラピューティクス・インコーポレイテッド | Hec1活性の調節因子およびそのための方法 |
| JP2016040288A (ja) * | 2010-03-17 | 2016-03-24 | タイヴェックス・セラピューティクス・コーポレイションTaivex Therapeutics Corporation | Hec1活性の調節因子およびそのための方法 |
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| JP2014526536A (ja) * | 2011-09-23 | 2014-10-06 | バイヤースドルフ・アクチエンゲゼルシヤフト | 芳香族アミドチアゾール、それを含有する化粧用または皮膚科用製剤、ならびに望ましくない皮膚の色素沈着を治療および予防するためのその使用 |
| JP2014526537A (ja) * | 2011-09-23 | 2014-10-06 | バイヤースドルフ・アクチエンゲゼルシヤフト | 複素環カルボニルアミノチアゾール、それを含有する化粧用または皮膚科用製剤、および望ましくない皮膚の色素沈着を治療・予防するためのその使用 |
| JP2017141242A (ja) * | 2011-09-23 | 2017-08-17 | バイエルスドルフ・アクチエンゲゼルシヤフトBeiersdorf AG | 芳香族アミドチアゾール、それを含有する化粧用または皮膚科用製剤、ならびに望ましくない皮膚の色素沈着を治療および予防するためのその使用 |
| US11071736B2 (en) | 2011-11-21 | 2021-07-27 | Taivex Therapeutics Corporation | Modulators of HEC1 activity and methods therefor |
| JP2017505295A (ja) * | 2013-12-19 | 2017-02-16 | バイエルスドルフ・アクチエンゲゼルシヤフトBeiersdorf AG | 敏感肌の予防及び治療のための、化粧品用又は皮膚用調製物におけるアルキルアミドチアゾールの使用 |
| JP2017526733A (ja) * | 2014-06-26 | 2017-09-14 | モナシュ ユニヴァーシティ | 酵素相互作用薬剤 |
| JP2018500388A (ja) * | 2014-11-18 | 2018-01-11 | ラットガーズ、ザ ステート ユニバーシティ オブ ニュージャージー | 代謝疾患及び癌の治療のための、新規ミトコンドリアアンカップラー |
| JP2023503217A (ja) * | 2019-10-02 | 2023-01-27 | 克洛索科学公司 | 抗老化遺伝子klothoの発現を誘導する化合物およびその用途 |
| JP7412546B2 (ja) | 2019-10-02 | 2024-01-12 | 克洛索科学公司 | 抗老化遺伝子klothoの発現を誘導する化合物およびその用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL188932A0 (en) | 2008-04-13 |
| US20100137315A1 (en) | 2010-06-03 |
| WO2007019251A3 (en) | 2007-05-31 |
| AU2006278592A1 (en) | 2007-02-15 |
| WO2007019251A9 (en) | 2007-04-19 |
| WO2007019251A2 (en) | 2007-02-15 |
| CA2617788A1 (en) | 2007-02-15 |
| US20070032531A1 (en) | 2007-02-08 |
| EP1928848A2 (en) | 2008-06-11 |
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