JP2009502111A5 - - Google Patents
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- Publication number
- JP2009502111A5 JP2009502111A5 JP2008501501A JP2008501501A JP2009502111A5 JP 2009502111 A5 JP2009502111 A5 JP 2009502111A5 JP 2008501501 A JP2008501501 A JP 2008501501A JP 2008501501 A JP2008501501 A JP 2008501501A JP 2009502111 A5 JP2009502111 A5 JP 2009502111A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- amino acid
- acid sequence
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 67
- 229920001184 polypeptide Polymers 0.000 claims 63
- 102000004196 processed proteins & peptides Human genes 0.000 claims 63
- 150000001413 amino acids Chemical group 0.000 claims 43
- 108091033319 polynucleotide Proteins 0.000 claims 26
- 239000002157 polynucleotide Substances 0.000 claims 26
- 102000040430 polynucleotide Human genes 0.000 claims 26
- 150000001875 compounds Chemical class 0.000 claims 24
- 230000004071 biological effect Effects 0.000 claims 17
- 239000002773 nucleotide Substances 0.000 claims 15
- 125000003729 nucleotide group Chemical group 0.000 claims 15
- 238000000034 method Methods 0.000 claims 14
- 206010006187 Breast cancer Diseases 0.000 claims 12
- 208000026310 Breast neoplasm Diseases 0.000 claims 12
- 230000013595 glycosylation Effects 0.000 claims 12
- 238000006206 glycosylation reaction Methods 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 11
- 108091081021 Sense strand Proteins 0.000 claims 10
- 108091028664 Ribonucleotide Proteins 0.000 claims 9
- 239000002336 ribonucleotide Substances 0.000 claims 9
- 125000002652 ribonucleotide group Chemical group 0.000 claims 9
- 230000000692 anti-sense effect Effects 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 6
- 235000018102 proteins Nutrition 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 238000012216 screening Methods 0.000 claims 6
- 239000013598 vector Substances 0.000 claims 6
- 239000004480 active ingredient Substances 0.000 claims 5
- 108700008625 Reporter Genes Proteins 0.000 claims 4
- 235000001014 amino acid Nutrition 0.000 claims 4
- 229940024606 amino acid Drugs 0.000 claims 4
- 239000003937 drug carrier Substances 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 claims 3
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 3
- 108020004459 Small interfering RNA Proteins 0.000 claims 3
- 229960001230 asparagine Drugs 0.000 claims 3
- 235000009582 asparagine Nutrition 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 239000004055 small Interfering RNA Substances 0.000 claims 2
- 230000002103 transcriptional effect Effects 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 230000005809 anti-tumor immunity Effects 0.000 claims 1
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70365805P | 2005-07-29 | 2005-07-29 | |
| US60/703,658 | 2005-07-29 | ||
| PCT/JP2006/315341 WO2007013670A2 (en) | 2005-07-29 | 2006-07-26 | Gene galnt6 as breast cancer marker and small interfering rnas directed against gene galnt6 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009502111A JP2009502111A (ja) | 2009-01-29 |
| JP2009502111A5 true JP2009502111A5 (https=) | 2009-05-14 |
| JP5109063B2 JP5109063B2 (ja) | 2012-12-26 |
Family
ID=37001011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008501501A Expired - Fee Related JP5109063B2 (ja) | 2005-07-29 | 2006-07-26 | 乳癌に関連する遺伝子およびポリペプチド |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8795976B2 (https=) |
| EP (1) | EP1910570B1 (https=) |
| JP (1) | JP5109063B2 (https=) |
| CN (1) | CN101278060B (https=) |
| DE (1) | DE602006021315D1 (https=) |
| ES (1) | ES2364078T3 (https=) |
| WO (1) | WO2007013670A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120214174A1 (en) * | 2009-08-25 | 2012-08-23 | Oncotherapy Science, Inc. | Gene and polypeptide relating to breast cancer |
| CN108997488B (zh) * | 2018-08-14 | 2021-07-30 | 湖南师范大学 | 具有抗乳腺癌活性的间斑寇蛛卵粒蛋白质及其制法与应用 |
| CN110184271A (zh) * | 2019-06-04 | 2019-08-30 | 遵义医科大学珠海校区 | 一种mRNA-like ncRNA、抑制其表达的反义RNA及两者的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7892730B2 (en) * | 2000-12-22 | 2011-02-22 | Sagres Discovery, Inc. | Compositions and methods for cancer |
| US20040029114A1 (en) * | 2001-01-24 | 2004-02-12 | Eos Technology, Inc. | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer |
| JP2005503760A (ja) | 2001-01-24 | 2005-02-10 | プロテイン デザイン ラブス， インコーポレイテッド | 乳癌の診断方法、組成物および乳癌のモジュレーターのスクリーニング方法 |
| US20030099974A1 (en) | 2001-07-18 | 2003-05-29 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits and methods for identification, assessment, prevention, and therapy of breast cancer |
| WO2004078035A2 (en) * | 2003-02-28 | 2004-09-16 | Bayer Pharmaceuticals Corporation | Expression profiles for breast cancer and methods of use |
| WO2004094636A1 (en) * | 2003-04-24 | 2004-11-04 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| EP1660677A2 (en) * | 2003-08-20 | 2006-05-31 | Oncotherapy Science, Inc. | Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc) |
| CN1898563B (zh) | 2003-09-24 | 2011-11-23 | 肿瘤疗法科学股份有限公司 | 诊断乳腺癌的方法 |
| EP1621637A1 (en) * | 2004-07-30 | 2006-02-01 | Institut Curie | ppGalNac-T6 mRNA or peptide as a new marker for the detection of cancer cells |
-
2006
- 2006-07-26 US US11/913,166 patent/US8795976B2/en not_active Expired - Fee Related
- 2006-07-26 WO PCT/JP2006/315341 patent/WO2007013670A2/en not_active Ceased
- 2006-07-26 DE DE602006021315T patent/DE602006021315D1/de active Active
- 2006-07-26 ES ES06782210T patent/ES2364078T3/es active Active
- 2006-07-26 CN CN2006800363649A patent/CN101278060B/zh not_active Expired - Fee Related
- 2006-07-26 JP JP2008501501A patent/JP5109063B2/ja not_active Expired - Fee Related
- 2006-07-26 EP EP06782210A patent/EP1910570B1/en not_active Not-in-force
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