JP2008546777A5 - - Google Patents
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- Publication number
- JP2008546777A5 JP2008546777A5 JP2008518219A JP2008518219A JP2008546777A5 JP 2008546777 A5 JP2008546777 A5 JP 2008546777A5 JP 2008518219 A JP2008518219 A JP 2008518219A JP 2008518219 A JP2008518219 A JP 2008518219A JP 2008546777 A5 JP2008546777 A5 JP 2008546777A5
- Authority
- JP
- Japan
- Prior art keywords
- gemcitabine
- pharmaceutically acceptable
- acceptable salt
- cancer
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 7
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 4
- 229960005277 gemcitabine Drugs 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 229960000397 bevacizumab Drugs 0.000 claims 3
- -1 Genfitanibu Chemical compound 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000000277 Splenic Neoplasms Diseases 0.000 claims 1
- 208000009956 adenocarcinoma Diseases 0.000 claims 1
- 239000003145 cytotoxic factor Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 229960003685 imatinib mesylate Drugs 0.000 claims 1
- YLMAHDNUQAMNNX-UHFFFAOYSA-N imatinib methanesulfonate Chemical compound CS(O)(=O)=O.C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 YLMAHDNUQAMNNX-UHFFFAOYSA-N 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- OHDXDNUPVVYWOV-UHFFFAOYSA-N n-methyl-1-(2-naphthalen-1-ylsulfanylphenyl)methanamine Chemical compound CNCC1=CC=CC=C1SC1=CC=CC2=CC=CC=C12 OHDXDNUPVVYWOV-UHFFFAOYSA-N 0.000 claims 1
- 201000002471 spleen cancer Diseases 0.000 claims 1
- QDLHCMPXEPAAMD-QAIWCSMKSA-N wortmannin Chemical compound C1([C@]2(C)C3=C(C4=O)OC=C3C(=O)O[C@@H]2COC)=C4[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O QDLHCMPXEPAAMD-QAIWCSMKSA-N 0.000 claims 1
- QDLHCMPXEPAAMD-UHFFFAOYSA-N wortmannin Natural products COCC1OC(=O)C2=COC(C3=O)=C2C1(C)C1=C3C2CCC(=O)C2(C)CC1OC(C)=O QDLHCMPXEPAAMD-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69367105P | 2005-06-24 | 2005-06-24 | |
| PCT/US2006/023063 WO2007001839A2 (en) | 2005-06-24 | 2006-06-13 | 4-anilino-3-quinolinecarbonitriles for the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546777A JP2008546777A (ja) | 2008-12-25 |
| JP2008546777A5 true JP2008546777A5 (enExample) | 2009-07-30 |
Family
ID=37575124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518219A Pending JP2008546777A (ja) | 2005-06-24 | 2006-06-13 | 癌の治療のための４−アニリノ−３−キノリンカルボニトリル |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20070010527A1 (enExample) |
| EP (1) | EP1893209A2 (enExample) |
| JP (1) | JP2008546777A (enExample) |
| KR (1) | KR20080027275A (enExample) |
| CN (1) | CN101252931A (enExample) |
| AR (1) | AR057403A1 (enExample) |
| AU (1) | AU2006262591A1 (enExample) |
| BR (1) | BRPI0611977A2 (enExample) |
| CA (1) | CA2610209A1 (enExample) |
| CR (1) | CR9539A (enExample) |
| EC (1) | ECSP078015A (enExample) |
| GT (1) | GT200600268A (enExample) |
| IL (1) | IL187792A0 (enExample) |
| MX (1) | MX2007016542A (enExample) |
| NI (1) | NI200700323A (enExample) |
| NO (1) | NO20076075L (enExample) |
| PE (1) | PE20070323A1 (enExample) |
| RU (1) | RU2007143434A (enExample) |
| TW (1) | TW200730177A (enExample) |
| WO (1) | WO2007001839A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1902029T5 (pl) | 2005-07-01 | 2022-08-29 | Wyeth Llc | Krystaliczne postacie 4-[(2,4-dichloro-5-metoksyfenylo)amino]-6-metoksy-7-[3(-4-metylo-1-piperazynylo)propoksy]-3-chinolino-karbonitrylu i sposoby ich wytwarzania |
| WO2013187967A1 (en) * | 2012-06-15 | 2013-12-19 | Institute For Cancer Research D/B/A The Research Institute Of Fox Case Cancer Center ("Fox Chase Cancer Center") | Sensitization of cancer cells to dna damage by inhibiting kinases essential for dna damage checkpoint control |
| WO2017134679A1 (en) * | 2016-02-03 | 2017-08-10 | Msn Laboratories Private Limited | Novel crystalline polymorphs of 4-[(2.4-dichioro-5-methoxvphenvl)aniinol- 6-methoxv-7-13-(4-methyl-l-piperazinvl)propoxvl-3-quinolinecarbonitrile and process for preparation thereof |
| CN107433391B (zh) * | 2017-07-03 | 2020-01-17 | 武汉逸飞激光设备有限公司 | 一种基于图像识别的焊接校准方法及系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6002008A (en) * | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| US6432979B1 (en) * | 1999-08-12 | 2002-08-13 | American Cyanamid Company | Method of treating or inhibiting colonic polyps and colorectal cancer |
| US6384051B1 (en) * | 2000-03-13 | 2002-05-07 | American Cyanamid Company | Method of treating or inhibiting colonic polyps |
| UA77200C2 (en) * | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
| AU2004289243B2 (en) * | 2003-11-06 | 2010-07-22 | Wyeth Llc | 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML) |
-
2006
- 2006-06-13 BR BRPI0611977-8A patent/BRPI0611977A2/pt not_active IP Right Cessation
- 2006-06-13 WO PCT/US2006/023063 patent/WO2007001839A2/en not_active Ceased
- 2006-06-13 RU RU2007143434/14A patent/RU2007143434A/ru not_active Application Discontinuation
- 2006-06-13 EP EP06773093A patent/EP1893209A2/en not_active Withdrawn
- 2006-06-13 JP JP2008518219A patent/JP2008546777A/ja active Pending
- 2006-06-13 KR KR1020077030196A patent/KR20080027275A/ko not_active Withdrawn
- 2006-06-13 CA CA002610209A patent/CA2610209A1/en not_active Abandoned
- 2006-06-13 CN CNA2006800223605A patent/CN101252931A/zh active Pending
- 2006-06-13 AU AU2006262591A patent/AU2006262591A1/en not_active Abandoned
- 2006-06-13 MX MX2007016542A patent/MX2007016542A/es not_active Application Discontinuation
- 2006-06-22 US US11/473,540 patent/US20070010527A1/en not_active Abandoned
- 2006-06-22 PE PE2006000716A patent/PE20070323A1/es not_active Application Discontinuation
- 2006-06-22 TW TW095122482A patent/TW200730177A/zh unknown
- 2006-06-22 GT GT200600268A patent/GT200600268A/es unknown
- 2006-06-23 AR ARP060102728A patent/AR057403A1/es not_active Application Discontinuation
-
2007
- 2007-11-22 CR CR9539A patent/CR9539A/es not_active Application Discontinuation
- 2007-11-27 NO NO20076075A patent/NO20076075L/no not_active Application Discontinuation
- 2007-11-29 IL IL187792A patent/IL187792A0/en unknown
- 2007-12-14 NI NI200700323A patent/NI200700323A/es unknown
- 2007-12-14 EC EC2007008015A patent/ECSP078015A/es unknown
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