TW200730177A - 4 anilino-3-quinolinecarbonitriles for the treatment of cancer - Google Patents

4 anilino-3-quinolinecarbonitriles for the treatment of cancer

Info

Publication number
TW200730177A
TW200730177A TW095122482A TW95122482A TW200730177A TW 200730177 A TW200730177 A TW 200730177A TW 095122482 A TW095122482 A TW 095122482A TW 95122482 A TW95122482 A TW 95122482A TW 200730177 A TW200730177 A TW 200730177A
Authority
TW
Taiwan
Prior art keywords
cancer
quinolinecarbonitriles
anilino
treatment
directed
Prior art date
Application number
TW095122482A
Other languages
English (en)
Inventor
Frank Charles Boschelli
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37575124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200730177(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of TW200730177A publication Critical patent/TW200730177A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
TW095122482A 2005-06-24 2006-06-22 4 anilino-3-quinolinecarbonitriles for the treatment of cancer TW200730177A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69367105P 2005-06-24 2005-06-24

Publications (1)

Publication Number Publication Date
TW200730177A true TW200730177A (en) 2007-08-16

Family

ID=37575124

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095122482A TW200730177A (en) 2005-06-24 2006-06-22 4 anilino-3-quinolinecarbonitriles for the treatment of cancer

Country Status (20)

Country Link
US (1) US20070010527A1 (zh)
EP (1) EP1893209A2 (zh)
JP (1) JP2008546777A (zh)
KR (1) KR20080027275A (zh)
CN (1) CN101252931A (zh)
AR (1) AR057403A1 (zh)
AU (1) AU2006262591A1 (zh)
BR (1) BRPI0611977A2 (zh)
CA (1) CA2610209A1 (zh)
CR (1) CR9539A (zh)
EC (1) ECSP078015A (zh)
GT (1) GT200600268A (zh)
IL (1) IL187792A0 (zh)
MX (1) MX2007016542A (zh)
NI (1) NI200700323A (zh)
NO (1) NO20076075L (zh)
PE (1) PE20070323A1 (zh)
RU (1) RU2007143434A (zh)
TW (1) TW200730177A (zh)
WO (1) WO2007001839A2 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1902029T5 (pl) * 2005-07-01 2022-08-29 Wyeth Llc Krystaliczne postacie 4-[(2,4-dichloro-5-metoksyfenylo)amino]-6-metoksy-7-[3(-4-metylo-1-piperazynylo)propoksy]-3-chinolino-karbonitrylu i sposoby ich wytwarzania
WO2013187967A1 (en) * 2012-06-15 2013-12-19 Institute For Cancer Research D/B/A The Research Institute Of Fox Case Cancer Center ("Fox Chase Cancer Center") Sensitization of cancer cells to dna damage by inhibiting kinases essential for dna damage checkpoint control
WO2017134679A1 (en) * 2016-02-03 2017-08-10 Msn Laboratories Private Limited Novel crystalline polymorphs of 4-[(2.4-dichioro-5-methoxvphenvl)aniinol- 6-methoxv-7-13-(4-methyl-l-piperazinvl)propoxvl-3-quinolinecarbonitrile and process for preparation thereof
CN107433391B (zh) * 2017-07-03 2020-01-17 武汉逸飞激光设备有限公司 一种基于图像识别的焊接校准方法及系统

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002008A (en) * 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6432979B1 (en) * 1999-08-12 2002-08-13 American Cyanamid Company Method of treating or inhibiting colonic polyps and colorectal cancer
US6384051B1 (en) * 2000-03-13 2002-05-07 American Cyanamid Company Method of treating or inhibiting colonic polyps
UA77200C2 (en) * 2001-08-07 2006-11-15 Wyeth Corp Antineoplastic combination of cci-779 and bkb-569
CA2543163A1 (en) * 2003-11-06 2005-05-26 Wyeth 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)

Also Published As

Publication number Publication date
WO2007001839A3 (en) 2007-04-26
MX2007016542A (es) 2008-03-04
CN101252931A (zh) 2008-08-27
NI200700323A (es) 2008-06-25
PE20070323A1 (es) 2007-05-04
JP2008546777A (ja) 2008-12-25
KR20080027275A (ko) 2008-03-26
CA2610209A1 (en) 2007-01-04
US20070010527A1 (en) 2007-01-11
CR9539A (es) 2008-02-20
RU2007143434A (ru) 2009-07-27
EP1893209A2 (en) 2008-03-05
AR057403A1 (es) 2007-12-05
AU2006262591A1 (en) 2007-01-04
BRPI0611977A2 (pt) 2010-10-13
WO2007001839A2 (en) 2007-01-04
GT200600268A (es) 2007-06-18
NO20076075L (no) 2008-03-18
IL187792A0 (en) 2008-11-03
ECSP078015A (es) 2008-01-23

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