JP2008546390A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008546390A5 JP2008546390A5 JP2008517126A JP2008517126A JP2008546390A5 JP 2008546390 A5 JP2008546390 A5 JP 2008546390A5 JP 2008517126 A JP2008517126 A JP 2008517126A JP 2008517126 A JP2008517126 A JP 2008517126A JP 2008546390 A5 JP2008546390 A5 JP 2008546390A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nthi
- composition
- polypeptide
- sequence number
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 208000015181 infectious disease Diseases 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 6
- 239000012472 biological sample Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 210000000959 ear middle Anatomy 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 101100431814 Escherichia coli (strain K12) yciB gene Proteins 0.000 claims 2
- 101150008329 LPPB gene Proteins 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 101100162215 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) agmR gene Proteins 0.000 claims 2
- 101100399642 Salmonella paratyphi A (strain ATCC 9150 / SARB42) lpp3 gene Proteins 0.000 claims 2
- 101100007845 Stigmatella aurantiaca (strain DW4/3-1) cspA gene Proteins 0.000 claims 2
- 101100028273 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) argF gene Proteins 0.000 claims 2
- 239000000074 antisense oligonucleotide Substances 0.000 claims 2
- 238000012230 antisense oligonucleotides Methods 0.000 claims 2
- 101150032882 arcB gene Proteins 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 claims 2
- 101150058203 cspD gene Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 101150097706 glpR gene Proteins 0.000 claims 2
- 101150107671 hisB gene Proteins 0.000 claims 2
- 101150117117 ihfB gene Proteins 0.000 claims 2
- 101150008361 licC gene Proteins 0.000 claims 2
- 101150005075 lpp2 gene Proteins 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 101150039901 mukF gene Proteins 0.000 claims 2
- 101150048280 ocd gene Proteins 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 101150047781 ptcA gene Proteins 0.000 claims 2
- 101150034471 rbsC gene Proteins 0.000 claims 2
- 230000010076 replication Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 101150055723 sapA gene Proteins 0.000 claims 2
- 150000003384 small molecules Chemical class 0.000 claims 2
- 101150107825 uxuA gene Proteins 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 210000004880 lymph fluid Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69121405P | 2005-06-16 | 2005-06-16 | |
| PCT/US2006/023428 WO2006138527A2 (en) | 2005-06-16 | 2006-06-15 | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012062469A Division JP2012120543A (ja) | 2005-06-16 | 2012-03-19 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546390A JP2008546390A (ja) | 2008-12-25 |
| JP2008546390A5 true JP2008546390A5 (enExample) | 2009-07-02 |
Family
ID=37057493
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517126A Pending JP2008546390A (ja) | 2005-06-16 | 2006-06-15 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2012062469A Pending JP2012120543A (ja) | 2005-06-16 | 2012-03-19 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2014095656A Pending JP2014147397A (ja) | 2005-06-16 | 2014-05-07 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2015224493A Pending JP2016054739A (ja) | 2005-06-16 | 2015-11-17 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2017000108A Pending JP2017074071A (ja) | 2005-06-16 | 2017-01-04 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012062469A Pending JP2012120543A (ja) | 2005-06-16 | 2012-03-19 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2014095656A Pending JP2014147397A (ja) | 2005-06-16 | 2014-05-07 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2015224493A Pending JP2016054739A (ja) | 2005-06-16 | 2015-11-17 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2017000108A Pending JP2017074071A (ja) | 2005-06-16 | 2017-01-04 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US8283114B2 (enExample) |
| EP (3) | EP2343312A1 (enExample) |
| JP (5) | JP2008546390A (enExample) |
| CA (2) | CA2871088A1 (enExample) |
| WO (1) | WO2006138527A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| BRPI0609460A2 (pt) * | 2005-03-30 | 2010-04-13 | Novartis Vaccines & Diagnostics Inc | haemophilus influenzae tipo b |
| US8785130B2 (en) * | 2005-07-07 | 2014-07-22 | Bio-Id Diagnostic Inc. | Use of markers including nucleotide sequence based codes to monitor methods of detection and identification of genetic material |
| US9132183B2 (en) * | 2007-03-09 | 2015-09-15 | Newport Laboratories | Modified live (JMSO strain) Haemophilus parasuis vaccine |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| WO2010092176A2 (en) * | 2009-02-13 | 2010-08-19 | Intercell Ag | Nontypable haemophilus influenzae antigens |
| KR101334981B1 (ko) * | 2010-06-10 | 2013-12-02 | 한국과학기술원 | 탄화수소 생성능을 가지는 변이 미생물 및 이를 이용한 탄화수소의 제조방법 |
| EP3567121B1 (en) | 2011-01-17 | 2023-08-30 | Life Technologies Corporation | Workflow for detection of ligands using nucleic acids |
| US10494671B2 (en) | 2011-01-17 | 2019-12-03 | Life Technologies Corporation | Enzymatic ligation of nucleic acids |
| US20120276145A1 (en) * | 2011-03-28 | 2012-11-01 | House Research Institute | Extracellular matrix proteins from haemophilus influenzae biofilms: targets for therapeutic or diagnostic use |
| JP2014516028A (ja) * | 2011-05-11 | 2014-07-07 | リースベック ヘルスケア スウェーデン アクティエボラーグ | ラミニン及びビトロネクチン結合特性を有するタンパク質ｆ−新規インフルエンザ菌付着因子 |
| CN104321078A (zh) * | 2012-04-26 | 2015-01-28 | 诺华股份有限公司 | 抗原和抗原组合 |
| WO2014138748A1 (en) | 2013-03-08 | 2014-09-12 | Research Institute At Nationwide Children's Hospital | Transcutaneous dosage formulation |
| US9052314B2 (en) | 2013-03-14 | 2015-06-09 | Silver Lake Research Corporation | Biomarkers for detecting the presence of bacteria |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| US10624934B2 (en) | 2014-03-06 | 2020-04-21 | Research Institute At Nationwide Children's Hospital | Prebiotic formulations |
| CA2941694A1 (en) | 2014-03-06 | 2015-09-11 | Research Institute At Nationwide Children's Hospital | Probiotic formulations and methods for use |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3307307A4 (en) * | 2015-06-09 | 2019-05-01 | The Board of Regents of the University of Oklahoma | COMPOSITIONS AND TREATMENTS FOR HAEMOPHILUS INFLUENZAE |
| AU2016303688B2 (en) | 2015-07-31 | 2023-06-15 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| CN106567949A (zh) * | 2015-10-12 | 2017-04-19 | 海南广天恒科技发展有限公司 | 燃气阀专用限流装置 |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| US20190134150A1 (en) * | 2016-04-27 | 2019-05-09 | Biocells (Beijing) Biotech Co., Ltd. | Therapeutic methods for excitatory neurotoxicity-related injuries |
| US11299751B2 (en) | 2016-04-29 | 2022-04-12 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| JP7514621B2 (ja) | 2017-01-04 | 2024-07-11 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | Ｄｎａｂｉｉワクチンおよび強化された活性を有する抗体 |
| AU2018206560B9 (en) | 2017-01-04 | 2025-04-03 | Research Institute At Nationwide Children's Hospital | Antibody fragments for the treatment of biofilm-related disorders |
| US20200178900A1 (en) * | 2017-05-18 | 2020-06-11 | NeuralDx Ltd. | Vestibulo-acoustic signal processing |
| CN107478627B (zh) * | 2017-08-30 | 2019-09-10 | 温州大学激光与光电智能制造研究院 | 基于荧光纤维丝示踪的壁湍流时空演化过程检测方法 |
| KR20210070331A (ko) | 2018-10-05 | 2021-06-14 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 생물막 제거를 위한 hmgb1 단백질 유도체 |
| EP3870154A4 (en) | 2018-10-22 | 2022-07-27 | Research Institute at Nationwide Children's Hospital | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF ANTIBIOTIC-INDUCED PATHOLOGIES USING PROBIOTICS IN BIOFILM STATE |
| US20220143168A1 (en) * | 2019-02-27 | 2022-05-12 | Evaxion Biotech A/S | Vaccines targeting H. influenzae |
| CN111693691B (zh) * | 2019-03-14 | 2023-09-05 | 天津华科泰生物技术有限公司 | 一种基于卟啉结构的聚合物标签 |
| WO2020247536A1 (en) | 2019-06-03 | 2020-12-10 | Research Institute At Nationwide Children's Hospital | Prebiotic formulations for prevention of sepsis and necroenterocolitis induced neurodevelopmental deficiencies |
| CN112575041B (zh) * | 2019-09-30 | 2022-12-13 | 江南大学 | 一种混合碳源高效发酵生产phb的工程菌及其应用 |
| EP4172616B1 (en) * | 2020-06-29 | 2025-07-30 | Waters Technologies Corporation | Chromatographic dimension selection in multidimensional liquid chromatography |
| CN112808285B (zh) * | 2021-01-14 | 2023-08-04 | 武汉科技大学 | 一种非均相类芬顿催化剂及其制备方法和应用 |
| CN114574456B (zh) * | 2022-03-18 | 2022-08-12 | 华南理工大学 | 一种亚硝酸盐还原酶突变体及其编码基因和应用 |
| CN120775878A (zh) * | 2025-07-04 | 2025-10-14 | 华中农业大学 | 一种副猪革拉瑟氏菌高效转座突变系统及其构建方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2218741A1 (en) * | 1995-04-21 | 1996-10-24 | Johns Hopkins University | Nucleotide sequence of the haemophilus influenzae rd genome, fragments thereof, and uses thereof |
| DE19728833A1 (de) | 1997-07-05 | 1999-01-07 | Bayer Ag | Verfahren zur Beseitigung von Oberflächengewässer verschmutzenden organischen Flüssigkeiten |
| EP1029052B1 (en) | 1997-11-06 | 2010-08-04 | Novartis Vaccines and Diagnostics S.r.l. | Neisserial antigens |
| AU2109700A (en) | 1999-01-22 | 2000-08-07 | Smithkline Beecham Biologicals (Sa) | Novel compounds |
| US6605709B1 (en) * | 1999-04-09 | 2003-08-12 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics |
| GB0026002D0 (en) | 2000-10-24 | 2000-12-13 | Smithkline Beecham Biolog | Novel compounds |
| JP2006519605A (ja) * | 2003-03-06 | 2006-08-31 | チルドレンズ ホスピタル， インコーポレイテッド | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
| CA2520386A1 (en) * | 2003-03-27 | 2004-10-14 | Children's Hospital, Inc. | Nontypeable haemophilus influenzae virulence factors |
| GB0410866D0 (en) * | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
-
2006
- 2006-06-15 CA CA2871088A patent/CA2871088A1/en not_active Abandoned
- 2006-06-15 EP EP10176053A patent/EP2343312A1/en not_active Withdrawn
- 2006-06-15 US US11/917,368 patent/US8283114B2/en not_active Expired - Fee Related
- 2006-06-15 WO PCT/US2006/023428 patent/WO2006138527A2/en not_active Ceased
- 2006-06-15 EP EP08022435A patent/EP2070945A1/en not_active Withdrawn
- 2006-06-15 EP EP06773314A patent/EP1899366A2/en not_active Withdrawn
- 2006-06-15 JP JP2008517126A patent/JP2008546390A/ja active Pending
- 2006-06-15 CA CA002612240A patent/CA2612240A1/en not_active Abandoned
-
2012
- 2012-03-19 JP JP2012062469A patent/JP2012120543A/ja active Pending
- 2012-09-12 US US13/612,176 patent/US8652773B2/en not_active Expired - Fee Related
-
2014
- 2014-01-09 US US14/151,227 patent/US9034642B2/en not_active Expired - Fee Related
- 2014-05-07 JP JP2014095656A patent/JP2014147397A/ja active Pending
-
2015
- 2015-04-15 US US14/687,548 patent/US20150218231A1/en not_active Abandoned
- 2015-11-17 JP JP2015224493A patent/JP2016054739A/ja active Pending
-
2016
- 2016-06-09 US US15/177,584 patent/US20160289278A1/en not_active Abandoned
-
2017
- 2017-01-04 JP JP2017000108A patent/JP2017074071A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008546390A5 (enExample) | ||
| JP2006519605A5 (enExample) | ||
| Choudhary et al. | Respiratory syncytial virus influences NF-κB-dependent gene expression through a novel pathway involving MAP3K14/NIK expression and nuclear complex formation with NF-κB2 | |
| CN106103715B (zh) | 沙门氏菌的非编码性rna及其鉴定和应用 | |
| JP2005511076A5 (enExample) | ||
| Girkin et al. | TLR2-mediated innate immune priming boosts lung anti-viral immunity | |
| JP2008525033A5 (enExample) | ||
| Stelzer-Braid et al. | Detection of viral and bacterial respiratory pathogens in patients with cystic fibrosis | |
| JP6793468B2 (ja) | シングルプレックス又はマルチプレックスアッセイにおいてヒトパルボウイルス核酸を検出及びａ型肝炎ウイルス核酸を検出するための組成物及び方法 | |
| Böttcher et al. | Detection of enterovirus D68 in patients hospitalised in three tertiary university hospitals in Germany, 2013 to 2014 | |
| JP5717127B2 (ja) | 新型インフルエンザウイルスのヘマグルチニンに結合するアプタマー | |
| WO2012102793A2 (en) | Mammalian genes involved in toxicity and infection | |
| WO2015006755A2 (en) | Recombinase polymerase amplification (rpa) method for leishmania spp. and trypanosoma cruzi | |
| Upadhyay et al. | Recent advancement in SARS-CoV-2 diagnosis, treatment, and vaccine formulation: a new paradigm of nanotechnology in strategic combating of COVID-19 pandemic | |
| Streblow et al. | Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology | |
| KR20220082125A (ko) | 코로나 바이러스에 특이적으로 결합하는 dna 앱타머 및 이의 용도 | |
| CN102188707B (zh) | Il-17抑制剂在制备治疗流感的药物中的用途 | |
| JP6286050B2 (ja) | トリインフルエンザウイルスのｍｉＲＮＡとその同定、検出および使用 | |
| Orlova et al. | Constitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice | |
| JP2009544326A (ja) | インターナリンｂ又はインターナリンａと結合可能な核酸リガンド | |
| Roig et al. | Spontaneous quinolone resistance in the zoonotic serovar of Vibrio vulnificus | |
| Niu et al. | Probiotic peptidoglycan skeleton enhances vaccine efficacy against MRSA by inducing trained immunity via the TLR2/JAK-STAT3 pathway | |
| JP2020524509A5 (enExample) | ||
| CN101979556B (zh) | 一种siRNA靶向分子及其应用 | |
| JP2008503569A5 (enExample) |