JP2006519605A5 - - Google Patents
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- JP2006519605A5 JP2006519605A5 JP2006506942A JP2006506942A JP2006519605A5 JP 2006519605 A5 JP2006519605 A5 JP 2006519605A5 JP 2006506942 A JP2006506942 A JP 2006506942A JP 2006506942 A JP2006506942 A JP 2006506942A JP 2006519605 A5 JP2006519605 A5 JP 2006519605A5
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- JP
- Japan
- Prior art keywords
- seq
- composition
- nthi
- polypeptide
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims 25
- 229920001184 polypeptide Polymers 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 208000035143 Bacterial infection Diseases 0.000 claims 6
- 208000022362 bacterial infectious disease Diseases 0.000 claims 6
- 241000894006 Bacteria Species 0.000 claims 5
- 239000012472 biological sample Substances 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 230000021164 cell adhesion Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000000959 ear middle Anatomy 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 101100431814 Escherichia coli (strain K12) yciB gene Proteins 0.000 claims 1
- 101150008329 LPPB gene Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 101100162215 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) agmR gene Proteins 0.000 claims 1
- 101100399642 Salmonella paratyphi A (strain ATCC 9150 / SARB42) lpp3 gene Proteins 0.000 claims 1
- 101100007845 Stigmatella aurantiaca (strain DW4/3-1) cspA gene Proteins 0.000 claims 1
- 101100028273 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) argF gene Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000000074 antisense oligonucleotide Substances 0.000 claims 1
- 238000012230 antisense oligonucleotides Methods 0.000 claims 1
- 101150032882 arcB gene Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 101150058203 cspD gene Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 101150097706 glpR gene Proteins 0.000 claims 1
- 101150107671 hisB gene Proteins 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 101150117117 ihfB gene Proteins 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 101150008361 licC gene Proteins 0.000 claims 1
- 101150005075 lpp2 gene Proteins 0.000 claims 1
- 210000004880 lymph fluid Anatomy 0.000 claims 1
- 101150039901 mukF gene Proteins 0.000 claims 1
- 101150048280 ocd gene Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 101150047781 ptcA gene Proteins 0.000 claims 1
- 101150034471 rbsC gene Proteins 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 101150055723 sapA gene Proteins 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- -1 uxA Proteins 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45313403P | 2003-03-06 | 2003-03-06 | |
| PCT/US2004/007001 WO2004078949A2 (en) | 2003-03-06 | 2004-03-05 | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010139968A Division JP2010279359A (ja) | 2003-03-06 | 2010-06-18 | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006519605A JP2006519605A (ja) | 2006-08-31 |
| JP2006519605A5 true JP2006519605A5 (enExample) | 2007-05-24 |
Family
ID=32962758
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006506942A Withdrawn JP2006519605A (ja) | 2003-03-06 | 2004-03-05 | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
| JP2010139968A Pending JP2010279359A (ja) | 2003-03-06 | 2010-06-18 | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
| JP2014017053A Pending JP2014132901A (ja) | 2003-03-06 | 2014-01-31 | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010139968A Pending JP2010279359A (ja) | 2003-03-06 | 2010-06-18 | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
| JP2014017053A Pending JP2014132901A (ja) | 2003-03-06 | 2014-01-31 | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
Country Status (5)
| Country | Link |
|---|---|
| US (7) | US7241867B2 (enExample) |
| EP (2) | EP2330117A1 (enExample) |
| JP (3) | JP2006519605A (enExample) |
| CA (2) | CA2796381A1 (enExample) |
| WO (1) | WO2004078949A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2520386A1 (en) * | 2003-03-27 | 2004-10-14 | Children's Hospital, Inc. | Nontypeable haemophilus influenzae virulence factors |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| BRPI0609460A2 (pt) * | 2005-03-30 | 2010-04-13 | Novartis Vaccines & Diagnostics Inc | haemophilus influenzae tipo b |
| CA2871088A1 (en) * | 2005-06-16 | 2006-12-28 | Lauren O. Bakaletz | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| US7384770B1 (en) * | 2007-01-09 | 2008-06-10 | Gas Technology Institute | Rapid quantification of acetic acid-producing bacteria using real-time PCR |
| WO2010092176A2 (en) * | 2009-02-13 | 2010-08-19 | Intercell Ag | Nontypable haemophilus influenzae antigens |
| WO2010123885A2 (en) * | 2009-04-20 | 2010-10-28 | Tufts Medical Center, Inc. | Iga1 protease polypeptide agents and uses thereof |
| CN103180459B (zh) * | 2010-07-09 | 2016-10-19 | 赛尔冉迪思股份有限公司 | 3-d目的基因组区域的测序策略 |
| AU2011299025B2 (en) | 2010-09-09 | 2015-07-09 | Nationwide Children's Hospital, Inc. | Compositions and methods for the removal of biofilms |
| JP5541137B2 (ja) | 2010-12-15 | 2014-07-09 | ソニー株式会社 | 撮像装置、電子機器、太陽電池、および、撮像装置の製造方法 |
| US11274144B2 (en) * | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US9745366B2 (en) | 2013-09-23 | 2017-08-29 | University Of Southern California | Compositions and methods for the prevention of microbial infections |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US10233234B2 (en) | 2014-01-13 | 2019-03-19 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| US10624934B2 (en) | 2014-03-06 | 2020-04-21 | Research Institute At Nationwide Children's Hospital | Prebiotic formulations |
| CA2941694A1 (en) | 2014-03-06 | 2015-09-11 | Research Institute At Nationwide Children's Hospital | Probiotic formulations and methods for use |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US20180207067A1 (en) | 2015-07-14 | 2018-07-26 | Research Institute at Nationwide Children's Hospit al | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| AU2016303688B2 (en) | 2015-07-31 | 2023-06-15 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| AU2018206560B9 (en) | 2017-01-04 | 2025-04-03 | Research Institute At Nationwide Children's Hospital | Antibody fragments for the treatment of biofilm-related disorders |
| JP7514621B2 (ja) | 2017-01-04 | 2024-07-11 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | Ｄｎａｂｉｉワクチンおよび強化された活性を有する抗体 |
| US11746136B2 (en) | 2017-03-15 | 2023-09-05 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| KR20210070331A (ko) | 2018-10-05 | 2021-06-14 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 생물막 제거를 위한 hmgb1 단백질 유도체 |
| EP3870154A4 (en) | 2018-10-22 | 2022-07-27 | Research Institute at Nationwide Children's Hospital | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF ANTIBIOTIC-INDUCED PATHOLOGIES USING PROBIOTICS IN BIOFILM STATE |
| US20220143168A1 (en) * | 2019-02-27 | 2022-05-12 | Evaxion Biotech A/S | Vaccines targeting H. influenzae |
| WO2020247536A1 (en) | 2019-06-03 | 2020-12-10 | Research Institute At Nationwide Children's Hospital | Prebiotic formulations for prevention of sepsis and necroenterocolitis induced neurodevelopmental deficiencies |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US453134A (en) | 1891-05-26 | Fire-escape | ||
| FR2682122B1 (fr) * | 1991-10-03 | 1995-06-09 | Pasteur Institut | Nouveaux genes d'helicobacter pylori. leur utilisation pour la preparation de souches recombinantes de h. pylori. |
| AU4490797A (en) * | 1996-09-23 | 1998-04-14 | Children's Hospital Of Philadelphia, The | Compositions and methods for treatment of infection caused by (haemophilus influenzae) and (streptococcus pneumoniae) |
| EP1029052B1 (en) * | 1997-11-06 | 2010-08-04 | Novartis Vaccines and Diagnostics S.r.l. | Neisserial antigens |
| US5997280A (en) | 1997-11-07 | 1999-12-07 | Maxon Corporation | Intelligent burner control system |
| EP1144643A1 (en) | 1999-01-15 | 2001-10-17 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Neisseria meningitidis antigen |
| AU2109700A (en) * | 1999-01-22 | 2000-08-07 | Smithkline Beecham Biologicals (Sa) | Novel compounds |
| GB0026002D0 (en) * | 2000-10-24 | 2000-12-13 | Smithkline Beecham Biolog | Novel compounds |
-
2004
- 2004-03-05 JP JP2006506942A patent/JP2006519605A/ja not_active Withdrawn
- 2004-03-05 CA CA2796381A patent/CA2796381A1/en not_active Abandoned
- 2004-03-05 WO PCT/US2004/007001 patent/WO2004078949A2/en not_active Ceased
- 2004-03-05 US US10/795,159 patent/US7241867B2/en not_active Expired - Fee Related
- 2004-03-05 EP EP10181932A patent/EP2330117A1/en not_active Withdrawn
- 2004-03-05 EP EP04718155A patent/EP1601688A2/en not_active Withdrawn
- 2004-03-05 CA CA002517899A patent/CA2517899A1/en not_active Abandoned
-
2007
- 2007-06-28 US US11/770,447 patent/US7638282B2/en not_active Expired - Fee Related
-
2009
- 2009-12-23 US US12/646,424 patent/US7816086B2/en not_active Expired - Fee Related
-
2010
- 2010-06-18 JP JP2010139968A patent/JP2010279359A/ja active Pending
- 2010-08-20 US US12/860,332 patent/US7998490B2/en not_active Expired - Fee Related
-
2011
- 2011-07-21 US US13/187,989 patent/US8236494B2/en not_active Expired - Fee Related
-
2012
- 2012-07-19 US US13/553,006 patent/US8628917B2/en not_active Expired - Fee Related
-
2013
- 2013-12-23 US US14/139,319 patent/US20140120107A1/en not_active Abandoned
-
2014
- 2014-01-31 JP JP2014017053A patent/JP2014132901A/ja active Pending
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