JP2008543915A - ２−（フェニルアミノ）ベンズイミダゾール誘導体及び低コンダクタンスカルシウム依存性カリウムチャネルのモジュレーターとしてのそれらの使用 - Google Patents
２−（フェニルアミノ）ベンズイミダゾール誘導体及び低コンダクタンスカルシウム依存性カリウムチャネルのモジュレーターとしてのそれらの使用 Download PDFInfo
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- JP2008543915A JP2008543915A JP2008517496A JP2008517496A JP2008543915A JP 2008543915 A JP2008543915 A JP 2008543915A JP 2008517496 A JP2008517496 A JP 2008517496A JP 2008517496 A JP2008517496 A JP 2008517496A JP 2008543915 A JP2008543915 A JP 2008543915A
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- Prior art keywords
- benzimidazol
- trifluoromethyl
- aniline
- disease
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Landscapes
- Health & Medical Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69225205P | 2005-06-21 | 2005-06-21 | |
| DKPA200500910 | 2005-06-21 | ||
| PCT/EP2006/063405 WO2006136580A2 (en) | 2005-06-21 | 2006-06-21 | 2-(phenylamino)benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008543915A true JP2008543915A (ja) | 2008-12-04 |
| JP2008543915A5 JP2008543915A5 (enExample) | 2009-07-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517496A Abandoned JP2008543915A (ja) | 2005-06-21 | 2006-06-21 | ２−（フェニルアミノ）ベンズイミダゾール誘導体及び低コンダクタンスカルシウム依存性カリウムチャネルのモジュレーターとしてのそれらの使用 |
Country Status (6)
| Country | Link |
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| US (1) | US7960561B2 (enExample) |
| EP (1) | EP1896427A2 (enExample) |
| JP (1) | JP2008543915A (enExample) |
| CA (1) | CA2612922A1 (enExample) |
| MX (1) | MX2007015689A (enExample) |
| WO (1) | WO2006136580A2 (enExample) |
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| GB0715103D0 (en) * | 2007-08-03 | 2007-09-12 | Lectus Therapeutics Ltd | Calcium ion channel modulators and uses thereof |
| CN113061089A (zh) | 2015-09-23 | 2021-07-02 | 凯瑞康宁生物工程（武汉）有限公司 | γ-羟基丁酸的前药及其组合物和用途 |
| CN109153667B (zh) * | 2016-02-24 | 2021-04-02 | 阿塞西翁制药公司 | 新型钾通道抑制剂 |
| WO2017160922A1 (en) * | 2016-03-16 | 2017-09-21 | Kalyra Pharmaceuticals, Inc. | Analgesic compounds |
| RU2725886C1 (ru) | 2017-03-30 | 2020-07-07 | ЭксДабл-Ю ЛЭБОРЕТРИЗ ИНК. | Бициклические гетероарильные производные и их получение и применение |
| CA3072668A1 (en) * | 2017-08-23 | 2019-02-28 | Acesion Pharma Aps | Benzimidazole derivatives useful as potassium channel inhibitors |
| ES2947089T3 (es) | 2018-09-30 | 2023-08-01 | Xwpharma Ltd | Compuestos como antagonistas del receptor histamínico 3 neuronal y usos de los mismos |
| WO2021127461A1 (en) | 2019-12-20 | 2021-06-24 | Xw Laboratories Limited | Methods of synthesizing 4-valyloxybutyric acid |
| US11357734B2 (en) | 2020-06-18 | 2022-06-14 | XWPharma Ltd. | Pharmaceutical granulations of water-soluble active pharmaceutical ingredients |
| KR20230011359A (ko) | 2020-06-18 | 2023-01-20 | 엑스더블유파마 리미티드 | 수용성 활성 약제 성분의 제어 방출 과립화물 |
| WO2022020621A1 (en) | 2020-07-24 | 2022-01-27 | XWPharma Ltd. | Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative |
| KR20230058151A (ko) | 2020-10-05 | 2023-05-02 | 엑스더블유파마 리미티드 | 감마-하이드록시부티르산 유도체의 변형된 방출 조성물 |
| TW202300139A (zh) | 2021-03-19 | 2023-01-01 | 凱瑞康寧生技股份有限公司 | γ-羟基丁酸衍生物的聯合釋放製劑的藥代動力學 |
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| BE632578A (enExample) * | 1963-05-22 | |||
| GB1171904A (en) * | 1965-10-21 | 1969-11-26 | Unilever Ltd | Anilinobenzimidazoles having Antibacterial Properties |
| JP2869561B2 (ja) | 1989-05-22 | 1999-03-10 | 大塚製薬株式会社 | 血小板粘着抑制剤 |
| CA2282398A1 (en) * | 1997-03-14 | 1998-09-17 | Steven M. Ronkin | Inhibitors of impdh enzyme |
| WO2001021160A2 (en) | 1999-09-23 | 2001-03-29 | Axxima Pharmaceuticals Aktiengesellschaft | Carboxymide and aniline derivatives as selective inhibitors of pathogens |
| DE10060292A1 (de) * | 2000-12-05 | 2002-06-20 | Aventis Pharma Gmbh | Verwendung substituierter Benzimidazole zur Herstellung eines Medikaments zur Behandlung von Krankheiten, welche durch Inhibierung des Na+/H+-Austauschers beeinflusst werden können und sie enthaltendes Medikament |
| CN100407791C (zh) | 2001-11-16 | 2008-07-30 | 株式会社Ntt都科摩 | 图像编码、译码方法、图像编码、译码装置及图像传送系统 |
| US20050054705A1 (en) | 2003-02-04 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
| DE10304294A1 (de) | 2003-02-04 | 2004-08-12 | Aventis Pharma Deutschland Gmbh | N-Substituierte(Benzoimidazol-2-yl)-phenyl, Verfahren zu ihrer Herstellung , ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| WO2004098494A2 (en) * | 2003-04-30 | 2004-11-18 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| WO2005044793A2 (en) | 2003-10-31 | 2005-05-19 | Takeda Pharmaceutical Company Limited | Nitrogen-containing fused heterocyclic compounds |
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Also Published As
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|---|---|
| US20090076106A1 (en) | 2009-03-19 |
| WO2006136580A3 (en) | 2007-04-12 |
| MX2007015689A (es) | 2008-02-21 |
| US7960561B2 (en) | 2011-06-14 |
| EP1896427A2 (en) | 2008-03-12 |
| CA2612922A1 (en) | 2006-12-28 |
| WO2006136580A2 (en) | 2006-12-28 |
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