MX2007015689A - Nuevos derivados de 2-(fenilamino)bencimidazol y su uso como moduladores de los canales de potasio activados por calcio de pequena conductancia. - Google Patents
Nuevos derivados de 2-(fenilamino)bencimidazol y su uso como moduladores de los canales de potasio activados por calcio de pequena conductancia.Info
- Publication number
- MX2007015689A MX2007015689A MX2007015689A MX2007015689A MX2007015689A MX 2007015689 A MX2007015689 A MX 2007015689A MX 2007015689 A MX2007015689 A MX 2007015689A MX 2007015689 A MX2007015689 A MX 2007015689A MX 2007015689 A MX2007015689 A MX 2007015689A
- Authority
- MX
- Mexico
- Prior art keywords
- benzimidazol
- trifluoromethyl
- aniline
- alkyl
- disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Dermatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69225205P | 2005-06-21 | 2005-06-21 | |
| DKPA200500910 | 2005-06-21 | ||
| PCT/EP2006/063405 WO2006136580A2 (en) | 2005-06-21 | 2006-06-21 | 2-(phenylamino)benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007015689A true MX2007015689A (es) | 2008-02-21 |
Family
ID=37526982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007015689A MX2007015689A (es) | 2005-06-21 | 2006-06-21 | Nuevos derivados de 2-(fenilamino)bencimidazol y su uso como moduladores de los canales de potasio activados por calcio de pequena conductancia. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7960561B2 (enExample) |
| EP (1) | EP1896427A2 (enExample) |
| JP (1) | JP2008543915A (enExample) |
| CA (1) | CA2612922A1 (enExample) |
| MX (1) | MX2007015689A (enExample) |
| WO (1) | WO2006136580A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0715103D0 (en) * | 2007-08-03 | 2007-09-12 | Lectus Therapeutics Ltd | Calcium ion channel modulators and uses thereof |
| US11427600B2 (en) | 2014-06-27 | 2022-08-30 | Nogra Pharma Limited | Aryl receptor modulators and methods of making and using the same |
| CN108283000B (zh) | 2015-09-23 | 2021-04-13 | 凯瑞康宁生物工程（武汉）有限公司 | γ-羟基丁酸的前药及其组合物和用途 |
| CN109153667B (zh) * | 2016-02-24 | 2021-04-02 | 阿塞西翁制药公司 | 新型钾通道抑制剂 |
| US10653681B2 (en) | 2016-03-16 | 2020-05-19 | Recurium Ip Holdings, Llc | Analgesic compounds |
| KR102510784B1 (ko) | 2017-03-30 | 2023-03-15 | 엑스더블유파마 리미티드 | 이환형 헤테로아릴 유도체 및 이의 제조 및 용도 |
| EP3672953B1 (en) * | 2017-08-23 | 2021-07-28 | Acesion Pharma ApS | Benzimidazole derivatives useful as potassium channel inhibitors |
| CN114042070A (zh) | 2018-09-30 | 2022-02-15 | 凯瑞康宁生物工程（武汉）有限公司 | 作为神经元组胺受体-3拮抗剂的化合物及其用途 |
| WO2021127461A1 (en) | 2019-12-20 | 2021-06-24 | Xw Laboratories Limited | Methods of synthesizing 4-valyloxybutyric acid |
| AU2021292406B2 (en) | 2020-06-18 | 2024-03-14 | XWPharma Ltd. | Controlled release granulations of water-soluble active pharmaceutical ingredients |
| KR102982616B1 (ko) | 2020-06-18 | 2026-06-26 | 엑스더블유파마 리미티드 | 수용성 원료의약품의 약학적 과립화제 |
| WO2022020621A1 (en) | 2020-07-24 | 2022-01-27 | XWPharma Ltd. | Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative |
| AU2021357705B2 (en) | 2020-10-05 | 2024-09-26 | XWPharma Ltd. | Modified release compositions of a gamma-hydroxybutyric acid derivative |
| DK4308086T3 (da) | 2021-03-19 | 2025-11-17 | Xwpharma Ltd | Farmakokinetik af formuleringer med kombineret frigivelse af et gamma-hydroxysmørsyrederivat |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE632578A (enExample) * | 1963-05-22 | |||
| GB1171904A (en) * | 1965-10-21 | 1969-11-26 | Unilever Ltd | Anilinobenzimidazoles having Antibacterial Properties |
| JP2869561B2 (ja) * | 1989-05-22 | 1999-03-10 | 大塚製薬株式会社 | 血小板粘着抑制剤 |
| ATE244717T1 (de) * | 1997-03-14 | 2003-07-15 | Vertex Pharma | Inhibitoren des impdh-enzyms |
| WO2001021160A2 (en) * | 1999-09-23 | 2001-03-29 | Axxima Pharmaceuticals Aktiengesellschaft | Carboxymide and aniline derivatives as selective inhibitors of pathogens |
| DE10060292A1 (de) * | 2000-12-05 | 2002-06-20 | Aventis Pharma Gmbh | Verwendung substituierter Benzimidazole zur Herstellung eines Medikaments zur Behandlung von Krankheiten, welche durch Inhibierung des Na+/H+-Austauschers beeinflusst werden können und sie enthaltendes Medikament |
| WO2003043345A1 (fr) | 2001-11-16 | 2003-05-22 | Ntt Docomo, Inc. | Procede de codage d'image, procede de decodage d'image, codeur et decodeur d'image, programme, signal de donnees informatiques et systeme d'emission d'image |
| DE10304294A1 (de) | 2003-02-04 | 2004-08-12 | Aventis Pharma Deutschland Gmbh | N-Substituierte(Benzoimidazol-2-yl)-phenyl, Verfahren zu ihrer Herstellung , ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US20050054705A1 (en) | 2003-02-04 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
| WO2004098494A2 (en) * | 2003-04-30 | 2004-11-18 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| US7714009B2 (en) | 2003-10-31 | 2010-05-11 | Takeda Pharmaceutical Company Limited | Nitrogen-containing fused heterocyclic compounds |
-
2006
- 2006-06-21 JP JP2008517496A patent/JP2008543915A/ja not_active Abandoned
- 2006-06-21 WO PCT/EP2006/063405 patent/WO2006136580A2/en not_active Ceased
- 2006-06-21 US US11/919,708 patent/US7960561B2/en not_active Expired - Fee Related
- 2006-06-21 EP EP06777399A patent/EP1896427A2/en not_active Withdrawn
- 2006-06-21 MX MX2007015689A patent/MX2007015689A/es not_active Application Discontinuation
- 2006-06-21 CA CA002612922A patent/CA2612922A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7960561B2 (en) | 2011-06-14 |
| JP2008543915A (ja) | 2008-12-04 |
| CA2612922A1 (en) | 2006-12-28 |
| WO2006136580A3 (en) | 2007-04-12 |
| EP1896427A2 (en) | 2008-03-12 |
| WO2006136580A2 (en) | 2006-12-28 |
| US20090076106A1 (en) | 2009-03-19 |
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