|
US2745785A
(en)
*
|
1952-10-29 |
1956-05-15 |
American Home Prod |
Therapeutic composition comprising tabular nu, nu'-dibenzylethylenediamine di-penicillin, and process for preparing same
|
|
US4798846A
(en)
*
|
1974-03-28 |
1989-01-17 |
Imperial Chemical Industries Plc |
Pharmaceutical compositions
|
|
GB1472793A
(en)
*
|
1974-03-28 |
1977-05-04 |
Ici Ltd |
Pharmaceutical compositions
|
|
US4073943A
(en)
*
|
1974-09-11 |
1978-02-14 |
Apoteksvarucentralen Vitrum Ab |
Method of enhancing the administration of pharmalogically active agents
|
|
US4725442A
(en)
*
|
1983-06-17 |
1988-02-16 |
Haynes Duncan H |
Microdroplets of water-insoluble drugs and injectable formulations containing same
|
|
US4826689A
(en)
*
|
1984-05-21 |
1989-05-02 |
University Of Rochester |
Method for making uniformly sized particles from water-insoluble organic compounds
|
|
US5023271A
(en)
*
|
1985-08-13 |
1991-06-11 |
California Biotechnology Inc. |
Pharmaceutical microemulsions
|
|
FR2608988B1
(fr)
*
|
1986-12-31 |
1991-01-11 |
Centre Nat Rech Scient |
Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
|
|
IL86211A
(en)
*
|
1987-05-04 |
1992-03-29 |
Ciba Geigy Ag |
Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
|
|
US5707634A
(en)
*
|
1988-10-05 |
1998-01-13 |
Pharmacia & Upjohn Company |
Finely divided solid crystalline powders via precipitation into an anti-solvent
|
|
US5188937A
(en)
*
|
1989-04-06 |
1993-02-23 |
Becton, Dickinson And Company |
Layered sandwich assay method for chlamydia and materials therefor
|
|
FR2651680B1
(fr)
*
|
1989-09-14 |
1991-12-27 |
Medgenix Group Sa |
Nouveau procede de preparation de microparticules lipidiques.
|
|
US5091187A
(en)
*
|
1990-04-26 |
1992-02-25 |
Haynes Duncan H |
Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
|
|
JP3282731B2
(ja)
*
|
1990-06-15 |
2002-05-20 |
メルク エンド カムパニー インコーポレーテッド |
結晶の構造および大きさを改良する結晶化方法
|
|
AU642066B2
(en)
*
|
1991-01-25 |
1993-10-07 |
Nanosystems L.L.C. |
X-ray contrast compositions useful in medical imaging
|
|
US5399363A
(en)
*
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5766635A
(en)
*
|
1991-06-28 |
1998-06-16 |
Rhone-Poulenc Rorer S.A. |
Process for preparing nanoparticles
|
|
US6063910A
(en)
*
|
1991-11-14 |
2000-05-16 |
The Trustees Of Princeton University |
Preparation of protein microparticles by supercritical fluid precipitation
|
|
US5389263A
(en)
*
|
1992-05-20 |
1995-02-14 |
Phasex Corporation |
Gas anti-solvent recrystallization and application for the separation and subsequent processing of RDX and HMX
|
|
SE9202128D0
(sv)
*
|
1992-07-09 |
1992-07-09 |
Astra Ab |
Precipitation of one or more active compounds in situ
|
|
US5417956A
(en)
*
|
1992-08-18 |
1995-05-23 |
Worcester Polytechnic Institute |
Preparation of nanophase solid state materials
|
|
AU660852B2
(en)
*
|
1992-11-25 |
1995-07-06 |
Elan Pharma International Limited |
Method of grinding pharmaceutical substances
|
|
US5298262A
(en)
*
|
1992-12-04 |
1994-03-29 |
Sterling Winthrop Inc. |
Use of ionic cloud point modifiers to prevent particle aggregation during sterilization
|
|
US5302401A
(en)
*
|
1992-12-09 |
1994-04-12 |
Sterling Winthrop Inc. |
Method to reduce particle size growth during lyophilization
|
|
DE4305003A1
(de)
*
|
1993-02-18 |
1994-08-25 |
Knoll Ag |
Verfahren zur Herstellung kolloidaler wäßriger Lösungen schwer löslicher Wirkstoffe
|
|
US5916596A
(en)
*
|
1993-02-22 |
1999-06-29 |
Vivorx Pharmaceuticals, Inc. |
Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
|
|
US5885486A
(en)
*
|
1993-03-05 |
1999-03-23 |
Pharmaciaand Upjohn Ab |
Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
|
|
FR2703927B1
(fr)
*
|
1993-04-13 |
1995-07-13 |
Coletica |
Utilisation d'une réaction de transacylation entre un polysaccharide estérifié et une polyamine pour former en milieu aqueux une membrane au moins en surface de particules gélifiées.
|
|
ES2106553T5
(es)
*
|
1993-07-19 |
2008-02-16 |
Angiotech Pharmaceuticals, Inc. |
Composiciones anti-angiogenicas y metodos de uso.
|
|
US5405864A
(en)
*
|
1993-10-15 |
1995-04-11 |
Syntex (U.S.A.) Inc. |
Chemotherapeutic maleimides
|
|
TW384224B
(en)
*
|
1994-05-25 |
2000-03-11 |
Nano Sys Llc |
Method of preparing submicron particles of a therapeutic or diagnostic agent
|
|
GB9413202D0
(en)
*
|
1994-06-30 |
1994-08-24 |
Univ Bradford |
Method and apparatus for the formation of particles
|
|
EP0783325B2
(en)
*
|
1994-09-27 |
2004-03-31 |
Amersham Health AS |
Contrast agent
|
|
US5720551A
(en)
*
|
1994-10-28 |
1998-02-24 |
Shechter; Tal |
Forming emulsions
|
|
DE4440337A1
(de)
*
|
1994-11-11 |
1996-05-15 |
Dds Drug Delivery Services Ges |
Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
|
|
US5716642A
(en)
*
|
1995-01-10 |
1998-02-10 |
Nano Systems L.L.C. |
Microprecipitation of nanoparticulate pharmaceutical agents using surface active material derived from similar pharmaceutical agents
|
|
US5518738A
(en)
*
|
1995-02-09 |
1996-05-21 |
Nanosystem L.L.C. |
Nanoparticulate nsaid compositions
|
|
US5591456A
(en)
*
|
1995-02-10 |
1997-01-07 |
Nanosystems L.L.C. |
Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer
|
|
US5510118A
(en)
*
|
1995-02-14 |
1996-04-23 |
Nanosystems Llc |
Process for preparing therapeutic compositions containing nanoparticles
|
|
AU695207B2
(en)
*
|
1995-03-28 |
1998-08-06 |
Fidia Farmaceutici S.P.A. |
Nanospheres comprising a biocompatible polysaccharide
|
|
US5605785A
(en)
*
|
1995-03-28 |
1997-02-25 |
Eastman Kodak Company |
Annealing processes for nanocrystallization of amorphous dispersions
|
|
IE75744B1
(en)
*
|
1995-04-03 |
1997-09-24 |
Elan Corp Plc |
Controlled release biodegradable micro- and nanospheres containing cyclosporin
|
|
IE80468B1
(en)
*
|
1995-04-04 |
1998-07-29 |
Elan Corp Plc |
Controlled release biodegradable nanoparticles containing insulin
|
|
SE9501384D0
(sv)
*
|
1995-04-13 |
1995-04-13 |
Astra Ab |
Process for the preparation of respirable particles
|
|
US6143211A
(en)
*
|
1995-07-21 |
2000-11-07 |
Brown University Foundation |
Process for preparing microparticles through phase inversion phenomena
|
|
US6245349B1
(en)
*
|
1996-02-23 |
2001-06-12 |
éLAN CORPORATION PLC |
Drug delivery compositions suitable for intravenous injection
|
|
US6231890B1
(en)
*
|
1996-05-02 |
2001-05-15 |
Taisho Pharmaceutical Co., Ltd. |
Suspension of sparingly water-soluble acidic drug
|
|
EP0920313A1
(en)
*
|
1996-07-01 |
1999-06-09 |
Sepracor, Inc. |
Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,s)-glycopyrrolate
|
|
ATE314055T1
(de)
*
|
1996-08-22 |
2006-01-15 |
Jagotec Ag |
Zubereitungen enthaltend mikropartikel von wasserunlöslichen stoffen und verfahren zu deren herstellung
|
|
US6344271B1
(en)
*
|
1998-11-06 |
2002-02-05 |
Nanoenergy Corporation |
Materials and products using nanostructured non-stoichiometric substances
|
|
DE19636150A1
(de)
*
|
1996-09-06 |
1998-03-12 |
Asta Medica Ag |
N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
|
|
US6048550A
(en)
*
|
1996-10-03 |
2000-04-11 |
Chan; Daniel C. F. |
Hydrophilic microparticles and methods to prepare same
|
|
US5874111A
(en)
*
|
1997-01-07 |
1999-02-23 |
Maitra; Amarnath |
Process for the preparation of highly monodispersed polymeric hydrophilic nanoparticles
|
|
US6045829A
(en)
*
|
1997-02-13 |
2000-04-04 |
Elan Pharma International Limited |
Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
|
|
WO1998035666A1
(en)
*
|
1997-02-13 |
1998-08-20 |
Nanosystems Llc |
Formulations of nanoparticle naproxen tablets
|
|
IT1292142B1
(it)
*
|
1997-06-12 |
1999-01-25 |
Maria Rosa Gasco |
Composizione farmaceutica in forma di microparticelle lipidiche solide atte alla somministrazione parenterale
|
|
US6217886B1
(en)
*
|
1997-07-14 |
2001-04-17 |
The Board Of Trustees Of The University Of Illinois |
Materials and methods for making improved micelle compositions
|
|
EP1011856B1
(en)
*
|
1997-08-05 |
2003-04-09 |
Microfluidics International Corporation |
Multiple stream high pressure mixer/reactor
|
|
US5834032A
(en)
*
|
1997-08-11 |
1998-11-10 |
Song; Moon K. |
Compositions and methods for treating diabetes
|
|
US6225329B1
(en)
*
|
1998-03-12 |
2001-05-01 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases (PTPases)
|
|
US6337092B1
(en)
*
|
1998-03-30 |
2002-01-08 |
Rtp Pharma Inc. |
Composition and method of preparing microparticles of water-insoluble substances
|
|
DE19946301A1
(de)
*
|
1998-04-02 |
2001-04-19 |
Asta Medica Ag |
Indolyl-3-glyoxylsäure-Derivate mit therapeutisch wertvollen Eigenschaften
|
|
DE19814838C2
(de)
*
|
1998-04-02 |
2001-01-18 |
Asta Medica Ag |
Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
|
|
ES2194477T3
(es)
*
|
1998-06-19 |
2003-11-16 |
Skyepharma Canada Inc |
Procedimiento para generar particulas de compuestos insolubles en agua con un tamaño de hasta 2000 nm.
|
|
FR2780901B1
(fr)
*
|
1998-07-09 |
2000-09-29 |
Coletica |
Particules, en particulier micro- ou nanoparticules de monosaccharides et oligosaccharides reticules, leurs procedes de preparation et compositions cosmetiques, pharmaceutiques ou alimentaires en contenant
|
|
US6238677B1
(en)
*
|
1998-08-18 |
2001-05-29 |
The United States Of America As Represented By The Secretary Of Agriculture |
Starch microcapsules for delivery of active agents
|
|
US8293277B2
(en)
*
|
1998-10-01 |
2012-10-23 |
Alkermes Pharma Ireland Limited |
Controlled-release nanoparticulate compositions
|
|
US6375986B1
(en)
*
|
2000-09-21 |
2002-04-23 |
Elan Pharma International Ltd. |
Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
|
|
US6365191B1
(en)
*
|
1999-02-17 |
2002-04-02 |
Dabur Research Foundation |
Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof
|
|
US6248363B1
(en)
*
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
US6045826A
(en)
*
|
1999-04-02 |
2000-04-04 |
National Research Council Of Canada |
Water-soluble compositions of bioactive lipophilic compounds
|
|
US6395300B1
(en)
*
|
1999-05-27 |
2002-05-28 |
Acusphere, Inc. |
Porous drug matrices and methods of manufacture thereof
|
|
US6610317B2
(en)
*
|
1999-05-27 |
2003-08-26 |
Acusphere, Inc. |
Porous paclitaxel matrices and methods of manufacture thereof
|
|
KR100331529B1
(ko)
*
|
1999-06-16 |
2002-04-06 |
민경윤 |
난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법
|
|
NZ519984A
(en)
*
|
2000-01-07 |
2004-03-26 |
Transform Pharmaceuticals Inc |
High-throughput formation, identification, and analysis of diverse solid-forms
|
|
CN1313080C
(zh)
*
|
2000-04-20 |
2007-05-02 |
斯凯伊药品加拿大公司 |
改进的水不溶性药物粒子的制备方法
|
|
US6561402B2
(en)
*
|
2000-05-16 |
2003-05-13 |
Black & Decker Inc. |
Ambidextrous drill holster
|
|
IT1320209B1
(it)
*
|
2000-06-21 |
2003-11-26 |
Marzoli Spa |
Gruppo per compattare un fascio di fibre tessili stirato in unfilatoio.
|
|
JP2004505761A
(ja)
*
|
2000-08-15 |
2004-02-26 |
ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ |
微小粒子
|
|
DE60138641D1
(de)
*
|
2000-10-27 |
2009-06-18 |
Baxter Healthcare Sa |
Herstellung von mikrokügelchen
|
|
JP4334869B2
(ja)
*
|
2000-12-01 |
2009-09-30 |
協和発酵キリン株式会社 |
溶解性または経口吸収性の改善された組成物
|
|
US20040022862A1
(en)
*
|
2000-12-22 |
2004-02-05 |
Kipp James E. |
Method for preparing small particles
|
|
US20030072807A1
(en)
*
|
2000-12-22 |
2003-04-17 |
Wong Joseph Chung-Tak |
Solid particulate antifungal compositions for pharmaceutical use
|
|
US20030096013A1
(en)
*
|
2000-12-22 |
2003-05-22 |
Jane Werling |
Preparation of submicron sized particles with polymorph control
|
|
US7193084B2
(en)
*
|
2000-12-22 |
2007-03-20 |
Baxter International Inc. |
Polymorphic form of itraconazole
|
|
US20040022861A1
(en)
*
|
2001-01-30 |
2004-02-05 |
Williams Robert O. |
Process for production of nanoparticles and microparticles by spray freezing into liquid
|
|
EP1258891A2
(en)
*
|
2001-05-17 |
2002-11-20 |
Shipley Co. L.L.C. |
Resistors
|
|
US20030044333A1
(en)
*
|
2001-06-13 |
2003-03-06 |
Johan Wanselin |
Device for an autoclave
|
|
US20060003012A9
(en)
*
|
2001-09-26 |
2006-01-05 |
Sean Brynjelsen |
Preparation of submicron solid particle suspensions by sonication of multiphase systems
|
|
US7112340B2
(en)
*
|
2001-10-19 |
2006-09-26 |
Baxter International Inc. |
Compositions of and method for preparing stable particles in a frozen aqueous matrix
|
|
DE10152306A1
(de)
*
|
2001-10-26 |
2003-07-24 |
Asta Medica Ag |
2-Acylindolderivate mit neuen therapeutisch wertvollen Eigenschaften
|
|
CA2479665C
(en)
*
|
2002-03-20 |
2011-08-30 |
Elan Pharma International Ltd. |
Nanoparticulate compositions of angiogenesis inhibitors
|
|
US6521923B1
(en)
*
|
2002-05-25 |
2003-02-18 |
Sirenza Microdevices, Inc. |
Microwave field effect transistor structure on silicon carbide substrate
|
|
US7211588B2
(en)
*
|
2003-07-25 |
2007-05-01 |
Zentaris Gmbh |
N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
|
|
DE102004031538A1
(de)
*
|
2004-06-29 |
2006-02-09 |
Baxter International Inc., Deerfield |
Pharmazeutische Darreichungsform zur oralen Verabreichung eines schwerlöslichen Wirkstoffs, Verfahren zu deren Herstellung und Kit
|
|
WO2006002887A1
(en)
*
|
2004-06-29 |
2006-01-12 |
Baxter International Inc. |
Aqueous drink solution of indibulin (d-24851) and an organic acid
|
|
AU2005304952B2
(en)
*
|
2004-11-08 |
2013-04-04 |
Baxter Healthcare S.A. |
Nanoparticulate compositions of tubulin inhibitors
|