JP2008540336A5 - - Google Patents

Download PDF

Info

Publication number
JP2008540336A5
JP2008540336A5 JP2008509119A JP2008509119A JP2008540336A5 JP 2008540336 A5 JP2008540336 A5 JP 2008540336A5 JP 2008509119 A JP2008509119 A JP 2008509119A JP 2008509119 A JP2008509119 A JP 2008509119A JP 2008540336 A5 JP2008540336 A5 JP 2008540336A5
Authority
JP
Japan
Prior art keywords
glp
agonist
brs
composition
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008509119A
Other languages
English (en)
Japanese (ja)
Other versions
JP5774264B2 (ja
JP2008540336A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/016024 external-priority patent/WO2007027225A2/en
Publication of JP2008540336A publication Critical patent/JP2008540336A/ja
Publication of JP2008540336A5 publication Critical patent/JP2008540336A5/ja
Application granted granted Critical
Publication of JP5774264B2 publication Critical patent/JP5774264B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2008509119A 2005-04-27 2006-04-26 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法 Expired - Fee Related JP5774264B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67573005P 2005-04-27 2005-04-27
US60/675,730 2005-04-27
PCT/US2006/016024 WO2007027225A2 (en) 2005-04-27 2006-04-26 Combination therapy for the treatment of obesity and diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012090364A Division JP2012136554A (ja) 2005-04-27 2012-04-11 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法

Publications (3)

Publication Number Publication Date
JP2008540336A JP2008540336A (ja) 2008-11-20
JP2008540336A5 true JP2008540336A5 (https=) 2009-06-18
JP5774264B2 JP5774264B2 (ja) 2015-09-09

Family

ID=37809319

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008509119A Expired - Fee Related JP5774264B2 (ja) 2005-04-27 2006-04-26 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法
JP2012090364A Withdrawn JP2012136554A (ja) 2005-04-27 2012-04-11 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法
JP2015057165A Pending JP2015120749A (ja) 2005-04-27 2015-03-20 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012090364A Withdrawn JP2012136554A (ja) 2005-04-27 2012-04-11 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法
JP2015057165A Pending JP2015120749A (ja) 2005-04-27 2015-03-20 肥満および糖尿病、ならびにそれらに関連する病態の処置のため、ならびに血中glp−1レベルを増大させることによって緩和される病態の処置のための、併用療法

Country Status (7)

Country Link
US (2) US8354241B2 (https=)
EP (1) EP1871362A2 (https=)
JP (3) JP5774264B2 (https=)
CN (1) CN101166527A (https=)
AU (1) AU2006285393A1 (https=)
CA (1) CA2605228A1 (https=)
WO (1) WO2007027225A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2006000008A (es) * 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
WO2008085888A1 (en) * 2007-01-05 2008-07-17 Arena Pharmaceuticals, Inc. G protein-coupled receptor and modulators thereof for the treatment of gaba-related neurological disorders including sleep-related disorders
EP2108960A1 (en) 2008-04-07 2009-10-14 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
WO2011080276A1 (en) 2009-12-29 2011-07-07 Genfit Pharmaceutical combinations comprising a dpp-4 inhibitor and a 1,3-diphenylprop-2-en-1-one derivative
GB201415598D0 (en) * 2014-09-03 2014-10-15 Univ Birmingham Elavated Itercranial Pressure Treatment
WO2017151728A1 (en) * 2016-03-01 2017-09-08 Board Of Supervisors Of Louisiana State Univ. And Agricultural And Mechanical College Indirect assessment of insulin release in a cell
KR20210149366A (ko) * 2020-06-02 2021-12-09 주식회사 고바이오랩 Icam-2에 결합하는 물질을 유효성분으로 포함하는 대사질환 예방 또는 치료용 약학 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US5462856A (en) 1990-07-19 1995-10-31 Bunsen Rush Laboratories, Inc. Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins
US6100042A (en) 1993-03-31 2000-08-08 Cadus Pharmaceutical Corporation Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
GB9719496D0 (en) 1997-09-13 1997-11-19 Glaxo Group Ltd G protien chimeras
EP1123391A2 (en) 1998-09-01 2001-08-16 BASF Aktiengesellschaft Methods for improving the function of heterologous g protein-coupled receptors
GB0006289D0 (en) 2000-03-15 2000-05-03 Smithkline Beecham Plc New use
EP1364024A2 (en) 2000-11-27 2003-11-26 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
DE10224844A1 (de) 2002-06-05 2004-01-08 Solvay Pharmaceuticals Gmbh Nicht-peptidische BRS-3-Agonisten
MXPA05007485A (es) 2003-01-14 2006-01-30 Arena Pharm Inc Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
EP1620555A4 (en) 2003-04-18 2006-09-13 Merck & Co Inc BOMBESIN RECEPTOR SUBTYP-3 (BRS-3) FROM RHESUS APPLE, SUCH NUCLEOTIDES AND USES THEREOF
PE20050948A1 (es) 2003-09-09 2005-12-16 Japan Tobacco Inc Compuestos de carbamoil-amina como inhibidores de la dipeptidil peptidasa iv
DOP2006000008A (es) 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1

Similar Documents

Publication Publication Date Title
CA2593427A1 (en) Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level
Boer et al. Incretin hormones and type 2 diabetes—mechanistic insights and therapeutic approaches
Coskun et al. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept
Rieg et al. Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice
JP4562394B2 (ja) 非アシル化グレリンを含む医薬組成物およびその治療的使用
JP6185914B2 (ja) 神経変性疾患の治療に使用するための医薬組成物
JP2012503013A5 (https=)
Sass et al. NK2R control of energy expenditure and feeding to treat metabolic diseases
Ong et al. Haplotypes in the urotensin II gene and urotensin II receptor gene are associated with insulin resistance and impaired glucose tolerance
CN101137668A (zh) 与可溶性G蛋白偶联受体(sGPCR)有关的组合物与方法
JP2022046619A (ja) 異所性石灰化障害を治療するための組成物およびそれを使用する方法
Nelson et al. Increase in cardiac myosin heavy-chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction
JP2008540336A5 (https=)
CN107847565A (zh) 用于肌肉减少症治疗的包括胰高血糖素样肽‑1 受体激动剂的药物组合物
Dalbøge et al. Neuromedin U inhibits food intake partly by inhibiting gastric emptying
CN114621327B (zh) GLP-1、GIP和Gcg多重受体激动蛋白质
WO2007134613A1 (en) Modulation of gpr120 activity in adipocytes/fat tissue
CN116333043A (zh) 具有抗肥胖及抗糖尿病功效的肽及其用途
Nakao Translational science: Newly emerging science in biology and medicine—Lessons from translational research on the natriuretic peptide family and leptin—
Matlik et al. Clinical and molecular analysis of a novel COLQ missense mutation causing congenital myasthenic syndrome in a Syrian family
Jeromson et al. Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet‐induced obesity
Li Is Glucagon-like peptide-1, an agent treating diabetes, a new hope for Alzheimer’s disease?
US20120157379A1 (en) Gastric Inhibitory Peptide Variants and Their Uses
CN118221798B (zh) 一种新型的glp-1r肽类激动剂及其应用
Gupta et al. Association of Circulating Orexin-A Level with Metabolic Risk Factors in North Indian Pre-Menopausal Women