JP2012503013A5 - - Google Patents
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- Publication number
- JP2012503013A5 JP2012503013A5 JP2011528020A JP2011528020A JP2012503013A5 JP 2012503013 A5 JP2012503013 A5 JP 2012503013A5 JP 2011528020 A JP2011528020 A JP 2011528020A JP 2011528020 A JP2011528020 A JP 2011528020A JP 2012503013 A5 JP2012503013 A5 JP 2012503013A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- cell
- composition
- binding protein
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9819308P | 2008-09-18 | 2008-09-18 | |
| US61/098,193 | 2008-09-18 | ||
| PCT/US2009/057592 WO2010033879A2 (en) | 2008-09-18 | 2009-09-18 | Inhibiting interaction between hif-1a and p300/cbp with hydrogen bond surrogate-based helices |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014186970A Division JP2015061833A (ja) | 2008-09-18 | 2014-09-12 | ＨＩＦ−１αと水素結合代替ヘリックスを有するｐ３００／ＣＢＰの間の相互作用の阻害 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012503013A JP2012503013A (ja) | 2012-02-02 |
| JP2012503013A5 true JP2012503013A5 (https=) | 2012-05-24 |
Family
ID=42040175
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011528020A Withdrawn JP2012503013A (ja) | 2008-09-18 | 2009-09-18 | ＨＩＦ−１αと水素結合代替ヘリックスを有するｐ３００／ＣＢＰの間の相互作用の阻害 |
| JP2014186970A Pending JP2015061833A (ja) | 2008-09-18 | 2014-09-12 | ＨＩＦ−１αと水素結合代替ヘリックスを有するｐ３００／ＣＢＰの間の相互作用の阻害 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014186970A Pending JP2015061833A (ja) | 2008-09-18 | 2014-09-12 | ＨＩＦ−１αと水素結合代替ヘリックスを有するｐ３００／ＣＢＰの間の相互作用の阻害 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9399666B2 (https=) |
| EP (1) | EP2344520B1 (https=) |
| JP (2) | JP2012503013A (https=) |
| CN (1) | CN102216322A (https=) |
| AU (1) | AU2009293020A1 (https=) |
| BR (1) | BRPI0919414A2 (https=) |
| CA (1) | CA2737614A1 (https=) |
| ES (1) | ES2446249T3 (https=) |
| WO (1) | WO2010033879A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2997973A1 (en) * | 2006-11-15 | 2016-03-23 | Dana-Farber Cancer Institute, Inc. | Stabalized maml peptides and uses thereof |
| BRPI0720306A2 (pt) | 2006-12-14 | 2014-02-04 | Aileron Therapeutics Inc | Sistemas de macrociclização da bis-sufidrila |
| ES2649941T3 (es) | 2007-02-23 | 2018-01-16 | Aileron Therapeutics, Inc. | Aminoácidos sustituidos para preparar péptidos macrocíclicos unidos a triazol |
| US8592377B2 (en) | 2007-03-28 | 2013-11-26 | President And Fellows Of Harvard College | Stitched polypeptides |
| WO2010033879A2 (en) | 2008-09-18 | 2010-03-25 | New York University | Inhibiting interaction between hif-1a and p300/cbp with hydrogen bond surrogate-based helices |
| CA2737922A1 (en) | 2008-09-22 | 2010-03-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| BRPI0920899A2 (pt) | 2008-11-24 | 2016-04-26 | Aileron Therapeutics Inc | macrociclos peptidomiméticos com propriedades melhoradas |
| US9175047B2 (en) | 2009-01-14 | 2015-11-03 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| CN102712675A (zh) | 2009-09-22 | 2012-10-03 | 爱勒让治疗公司 | 拟肽大环化合物 |
| ES2711526T3 (es) | 2010-08-13 | 2019-05-06 | Aileron Therapeutics Inc | Macrociclos peptidomiméticos |
| US8511577B2 (en) | 2011-02-24 | 2013-08-20 | Nest Labs, Inc. | Thermostat with power stealing delay interval at transitions between power stealing states |
| ES2586411T3 (es) | 2011-03-04 | 2016-10-14 | New York University | Macrociclos sustitutos de enlace de hidrógeno como moduladores de Ras |
| TW201806968A (zh) | 2011-10-18 | 2018-03-01 | 艾利倫治療公司 | 擬肽巨環化合物 |
| US9376469B2 (en) | 2011-12-21 | 2016-06-28 | New York University | Proteolytically resistant hydrogen bond surrogate helices |
| BR112014020103A2 (pt) | 2012-02-15 | 2018-10-09 | Aileron Therapeutics, Inc. | macrociclos peptidomiméticos |
| EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES |
| WO2014071241A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
| US20140205681A1 (en) * | 2013-01-19 | 2014-07-24 | New York University | HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION |
| WO2014113794A2 (en) * | 2013-01-19 | 2014-07-24 | New York University | Oligooxopiperazines for p53 reactivation |
| US20150065436A1 (en) * | 2013-09-03 | 2015-03-05 | University Of Southern California | INHIBITING INTERACTION BETWEEN HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED HELICES |
| EP3197478A4 (en) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| AU2015320545C1 (en) | 2014-09-24 | 2020-05-14 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| WO2016154058A1 (en) | 2015-03-20 | 2016-09-29 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| WO2017044633A1 (en) | 2015-09-10 | 2017-03-16 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of mcl-1 |
| WO2018008984A1 (ko) * | 2016-07-05 | 2018-01-11 | 이화여자대학교 산학협력단 | 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6986881B1 (en) | 1999-06-04 | 2006-01-17 | Dana-Farber Cancer Institute, Inc. | Identification of compounds that modify transcriptional responses to hypoxia |
| GB0211920D0 (en) | 2002-05-23 | 2002-07-03 | Isis Innovations Ltd | Assay |
| US7202332B2 (en) * | 2004-05-27 | 2007-04-10 | New York University | Methods for preparing internally constrained peptides and peptidomimetics |
| ITMI20042477A1 (it) | 2004-12-23 | 2005-03-23 | Cell Therapeutics Europe Srl | Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche |
| KR100860060B1 (ko) * | 2006-10-12 | 2008-09-24 | 한국과학기술연구원 | ＨＩＦ-１α Ｃ-말단 펩타이드와 ＣＢＰ 또는 ｐ３００단백질과의 결합을 정량분석하는 방법 및 상기 방법을이용한 단백질 복합체 형성을 저해하는 억제제의 스크리닝방법 |
| WO2010033879A2 (en) | 2008-09-18 | 2010-03-25 | New York University | Inhibiting interaction between hif-1a and p300/cbp with hydrogen bond surrogate-based helices |
| US20120115783A1 (en) * | 2008-09-22 | 2012-05-10 | Alleron therapeutics, Inc | Peptidomimetic macrocycles |
-
2009
- 2009-09-18 WO PCT/US2009/057592 patent/WO2010033879A2/en not_active Ceased
- 2009-09-18 CA CA2737614A patent/CA2737614A1/en not_active Abandoned
- 2009-09-18 ES ES09815315.8T patent/ES2446249T3/es active Active
- 2009-09-18 JP JP2011528020A patent/JP2012503013A/ja not_active Withdrawn
- 2009-09-18 AU AU2009293020A patent/AU2009293020A1/en not_active Abandoned
- 2009-09-18 CN CN2009801461214A patent/CN102216322A/zh active Pending
- 2009-09-18 EP EP09815315.8A patent/EP2344520B1/en not_active Not-in-force
- 2009-09-18 BR BRPI0919414A patent/BRPI0919414A2/pt not_active IP Right Cessation
- 2009-09-18 US US13/119,108 patent/US9399666B2/en active Active
-
2014
- 2014-09-12 JP JP2014186970A patent/JP2015061833A/ja active Pending
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