ITMI20042477A1 - Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche - Google Patents

Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche

Info

Publication number
ITMI20042477A1
ITMI20042477A1 IT002477A ITMI20042477A ITMI20042477A1 IT MI20042477 A1 ITMI20042477 A1 IT MI20042477A1 IT 002477 A IT002477 A IT 002477A IT MI20042477 A ITMI20042477 A IT MI20042477A IT MI20042477 A1 ITMI20042477 A1 IT MI20042477A1
Authority
IT
Italy
Prior art keywords
dichethodypiperazines
structuring
antibiotics
preparation
pharmaceutical compositions
Prior art date
Application number
IT002477A
Other languages
English (en)
Inventor
Mara Cassin
Gennaro Colella
Munari Sergio De
Mario Grugni
Ernesto Menta
Original Assignee
Cell Therapeutics Europe Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics Europe Srl filed Critical Cell Therapeutics Europe Srl
Priority to IT002477A priority Critical patent/ITMI20042477A1/it
Publication of ITMI20042477A1 publication Critical patent/ITMI20042477A1/it
Priority to MX2007007503A priority patent/MX2007007503A/es
Priority to JP2007547281A priority patent/JP2008525336A/ja
Priority to CNA2005800440034A priority patent/CN101083991A/zh
Priority to EP05824988A priority patent/EP1827442A1/en
Priority to PCT/EP2005/013457 priority patent/WO2006066775A1/en
Priority to KR1020077014106A priority patent/KR20070102492A/ko
Priority to ZA200704915A priority patent/ZA200704915B/xx
Priority to US11/793,860 priority patent/US20080255099A1/en
Priority to AU2005318535A priority patent/AU2005318535A1/en
Priority to CA002592002A priority patent/CA2592002A1/en
Priority to IL184114A priority patent/IL184114A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT002477A 2004-12-23 2004-12-23 Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche ITMI20042477A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT002477A ITMI20042477A1 (it) 2004-12-23 2004-12-23 Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche
CA002592002A CA2592002A1 (en) 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions
EP05824988A EP1827442A1 (en) 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions
JP2007547281A JP2008525336A (ja) 2004-12-23 2005-12-14 抗血管新生医薬組成物を調製するためのジケトジチオピペラジン抗生物質の使用
CNA2005800440034A CN101083991A (zh) 2004-12-23 2005-12-14 二酮二硫代哌嗪抗生素用于制备抗血管生成药物组合物的用途
MX2007007503A MX2007007503A (es) 2004-12-23 2005-12-14 Uso de antibioticos de dicetoditiopiperazina para la preparacion de composiciones farmaceuticas anti-angiogenicas.
PCT/EP2005/013457 WO2006066775A1 (en) 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions
KR1020077014106A KR20070102492A (ko) 2004-12-23 2005-12-14 혈관형성 억제 약학적 조성물의 제조를 위한디케토디티오피페라진 항생제의 용도
ZA200704915A ZA200704915B (en) 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions
US11/793,860 US20080255099A1 (en) 2004-12-23 2005-12-14 Use of Diketodithiopiperazine Antibiotics for the Preparation of Antiangiogenic Pharmaceutical Compositions
AU2005318535A AU2005318535A1 (en) 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions
IL184114A IL184114A0 (en) 2004-12-23 2007-06-21 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002477A ITMI20042477A1 (it) 2004-12-23 2004-12-23 Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche

Publications (1)

Publication Number Publication Date
ITMI20042477A1 true ITMI20042477A1 (it) 2005-03-23

Family

ID=35929666

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002477A ITMI20042477A1 (it) 2004-12-23 2004-12-23 Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche

Country Status (12)

Country Link
US (1) US20080255099A1 (it)
EP (1) EP1827442A1 (it)
JP (1) JP2008525336A (it)
KR (1) KR20070102492A (it)
CN (1) CN101083991A (it)
AU (1) AU2005318535A1 (it)
CA (1) CA2592002A1 (it)
IL (1) IL184114A0 (it)
IT (1) ITMI20042477A1 (it)
MX (1) MX2007007503A (it)
WO (1) WO2006066775A1 (it)
ZA (1) ZA200704915B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008112014A1 (en) * 2006-10-05 2008-09-18 Mayo Foundation For Medical Education And Research Methods and compositions for treating cancer
ES2325724B1 (es) 2008-03-11 2010-05-31 FUNDACION DE LA COMUNIDAD VALENCIANA "CENTRO DE INVESTIGACIONES PRINCIPE FELIPE" Composicion farmaceutica para inhibir el factor de transcripcion inducible por hipoxia. moduladores de procesos patologicos de angiogenesis, oncogenesis, inflamacion, apoptosis y terapia celular.
JP2012503013A (ja) 2008-09-18 2012-02-02 ニューヨーク ユニバーシティ ＨＩＦ−１αと水素結合代替ヘリックスを有するｐ３００／ＣＢＰの間の相互作用の阻害
KR101157078B1 (ko) 2009-10-27 2012-06-21 한국과학기술연구원 아스퍼질러스 ｋｍｄ 901 균주, 이로부터 분리된 다이케토피페라진 화합물, 및 이를 함유하는 암 예방 또는 치료용 조성물
US20120219568A1 (en) * 2011-02-24 2012-08-30 Zhejiang University Epidithiodioxopiprazines and uses thereof in treating cancer
JP6208667B2 (ja) 2011-10-03 2017-10-04 ユニベルシテ リブレ デ ブリュッセル 持続的ｈｉｖ感染症を処置するためのｈｉｖ−１遺伝子発現の再活性化
JP2014528959A (ja) * 2011-10-03 2014-10-30 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Ｔｈ２介在性疾患の処置のための方法および薬学的組成物
US9765090B2 (en) 2011-11-25 2017-09-19 Ewha University-Industry Collaboration Foundation Epidithiodioxopiperazine compound or its derivatives, and the use thereof
CN104334541A (zh) 2012-02-16 2015-02-04 纽约大学 使用低聚氧代哌嗪非肽螺旋模拟物对低氧诱导基因表达的控制
AU2013309515B2 (en) * 2012-08-29 2018-06-28 University Of Southern California Compositions and methods for inhibiting activity of hypoxia-inducible transcription factor complex and its use for treatment of tumors
WO2014066435A1 (en) 2012-10-22 2014-05-01 City Of Hope Etp derivatives
ES2946052T3 (es) * 2013-05-24 2023-07-12 Vasthera Co Ltd Compuesto de epiditiodioxopiperazina o sus derivados, y el uso del mismo
CN103550222A (zh) * 2013-11-05 2014-02-05 南京医科大学 毛壳素在制备预防和治疗糖尿病药物中的应用
US9636340B2 (en) 2013-11-12 2017-05-02 Ayyappan K. Rajasekaran Kinase inhibitors
WO2018008984A1 (ko) * 2016-07-05 2018-01-11 이화여자대학교 산학협력단 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물
US10822353B2 (en) 2016-09-15 2020-11-03 City Of Hope Dithio ETP derivatives
CN107261137B (zh) * 2017-05-22 2021-04-13 中国人民解放军第二军医大学 两种抗her2抗体-毛壳素偶联物及其制备方法和抗肿瘤应用
KR102091730B1 (ko) * 2017-07-05 2020-03-23 바스테라 주식회사 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물
KR102599052B1 (ko) * 2019-08-28 2023-11-07 바스테라 주식회사 에피디티오디옥소피페라진 유도체, 또는 이들의 약학적으로 허용 가능한 염을 포함하는 고형암의 예방 또는 치료용 약학적 조성물
CN112626039B (zh) * 2020-12-22 2022-10-25 广东省微生物研究所（广东省微生物分析检测中心） 一种氧化还原酶GliT及其在抵抗真菌毒素中应用
WO2024005556A1 (en) * 2022-06-29 2024-01-04 Vasthera Co., Ltd. Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212051A (en) * 1984-05-18 1988-10-28 Univ Australian Immune response suppression; certain epipolythio- dioxopiperazine derivatives and their preparation
JPS61277617A (ja) * 1985-05-31 1986-12-08 Yakult Honsha Co Ltd 坑血小板凝集剤
CN1215433A (zh) * 1996-12-02 1999-04-28 味之素株式会社 胶霉毒素衍生物及由它制成的抗癌药

Also Published As

Publication number Publication date
WO2006066775A1 (en) 2006-06-29
US20080255099A1 (en) 2008-10-16
IL184114A0 (en) 2007-10-31
EP1827442A1 (en) 2007-09-05
CA2592002A1 (en) 2006-06-29
MX2007007503A (es) 2007-09-11
JP2008525336A (ja) 2008-07-17
ZA200704915B (en) 2008-11-26
CN101083991A (zh) 2007-12-05
KR20070102492A (ko) 2007-10-18
AU2005318535A1 (en) 2006-06-29

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