JP2008538114A - 20−アルキル、ジェミニビタミンd3化合物及びその使用方法 - Google Patents

20−アルキル、ジェミニビタミンd3化合物及びその使用方法 Download PDF

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JP2008538114A
JP2008538114A JP2008503267A JP2008503267A JP2008538114A JP 2008538114 A JP2008538114 A JP 2008538114A JP 2008503267 A JP2008503267 A JP 2008503267A JP 2008503267 A JP2008503267 A JP 2008503267A JP 2008538114 A JP2008538114 A JP 2008538114A
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compound
hydroxy
vitamin
disease
methyl
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JP2008538114A5 (enExample
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ジャンコフスキー パウエル
アール ウスココヴィッチ ミラン
アドリーニ ルシアーノ
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ビオクセル エッセ ピ ア
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
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  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
JP2008503267A 2005-03-23 2006-03-23 20−アルキル、ジェミニビタミンd3化合物及びその使用方法 Pending JP2008538114A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66439705P 2005-03-23 2005-03-23
US66436705P 2005-03-23 2005-03-23
PCT/US2006/011000 WO2006102647A1 (en) 2005-03-23 2006-03-23 20-alkyl, gemini vitamin d3 compounds and methods of use thereof

Publications (2)

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JP2008538114A true JP2008538114A (ja) 2008-10-09
JP2008538114A5 JP2008538114A5 (enExample) 2009-05-07

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US (1) US20090099140A1 (enExample)
EP (1) EP1879596A4 (enExample)
JP (1) JP2008538114A (enExample)
CA (1) CA2601914A1 (enExample)
TW (1) TW200738244A (enExample)
WO (1) WO2006102647A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009115398A1 (en) * 2008-03-18 2009-09-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Vitamin d compounds for the treatment of biliary diseases
CN102628872A (zh) * 2012-03-31 2012-08-08 广州菲康生物技术有限公司 25羟基维生素d检测试剂盒及其制备方法
US20130295083A1 (en) * 2012-05-02 2013-11-07 Wisconsin Alumni Research Foundation 2a-Methyl-19-nor-(20S)-1a,25-dihydroxyvitamin D3 (2AMD) or 2 methylene-19-nor-(20S)-1a,25-dihydroxyvitamin D3 (2MD) Support Survival and Function of Transplanted Islet Cells In Type 1 Diabetes
CN102692514A (zh) * 2012-06-21 2012-09-26 厦门大学 血液25-羟基维生素d3腺癌检测试剂盒及其制备方法
WO2016065052A1 (en) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Insulin vitamin d conjugates
JP6946182B2 (ja) 2014-10-22 2021-10-06 エクステンド バイオサイエンシズ インコーポレーテッドExtend Biosciences, Inc 治療用ビタミンdコンジュゲート
JP2025534350A (ja) 2022-09-30 2025-10-15 エクステンド バイオサイエンシズ インコーポレーテッド 長時間作用型副甲状腺ホルモン

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1045714A (ja) * 1996-05-23 1998-02-17 F Hoffmann La Roche Ag フッ素化ビタミンd3類似体
US6030962A (en) * 1997-04-28 2000-02-29 Synttex (U.S.A.) Inc. Vitamin D3 analogs with bis C-20 side chains
JP2000510875A (ja) * 1997-04-28 2000-08-22 エフ・ホフマン−ラ ロシュ アーゲー ビスc−20側鎖を有するビタミンd▲下3▼類似体
JP2002509888A (ja) * 1998-03-27 2002-04-02 オレゴン ヘルス サイエンシーズ ユニバーシティー 腫瘍および他の過増殖性疾患の治療におけるビタミンdおよびその類似体
US6516294B1 (en) * 1999-07-01 2003-02-04 The Regents Of The University Of California Nuclear receptor for 1α,25-dihydroxyvitamin D3 useful for selection of vitamin D3 ligands and a method therefor
WO2003028674A2 (en) * 2001-10-02 2003-04-10 Cedars-Sinai Medical Center Method for stimulating hair growth by administering vitamin d analogs
WO2004098522A2 (en) * 2003-04-30 2004-11-18 Bioxell S.P.A. Gemini vitamin d3 compounds and methods of use thereof
WO2006117684A1 (en) * 2005-03-23 2006-11-09 Bioxell S.P.A. Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin d3 compounds

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1045714A (ja) * 1996-05-23 1998-02-17 F Hoffmann La Roche Ag フッ素化ビタミンd3類似体
US6030962A (en) * 1997-04-28 2000-02-29 Synttex (U.S.A.) Inc. Vitamin D3 analogs with bis C-20 side chains
JP2000510875A (ja) * 1997-04-28 2000-08-22 エフ・ホフマン−ラ ロシュ アーゲー ビスc−20側鎖を有するビタミンd▲下3▼類似体
JP2002509888A (ja) * 1998-03-27 2002-04-02 オレゴン ヘルス サイエンシーズ ユニバーシティー 腫瘍および他の過増殖性疾患の治療におけるビタミンdおよびその類似体
US6521608B1 (en) * 1998-03-27 2003-02-18 Oregon Health & Science University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
US6516294B1 (en) * 1999-07-01 2003-02-04 The Regents Of The University Of California Nuclear receptor for 1α,25-dihydroxyvitamin D3 useful for selection of vitamin D3 ligands and a method therefor
WO2003028674A2 (en) * 2001-10-02 2003-04-10 Cedars-Sinai Medical Center Method for stimulating hair growth by administering vitamin d analogs
WO2004098522A2 (en) * 2003-04-30 2004-11-18 Bioxell S.P.A. Gemini vitamin d3 compounds and methods of use thereof
JP2006525367A (ja) * 2003-04-30 2006-11-09 ビオクセル エッセ ピ ア ジェミニビタミンd3化合物及びその使用方法
WO2006117684A1 (en) * 2005-03-23 2006-11-09 Bioxell S.P.A. Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin d3 compounds

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Publication number Publication date
CA2601914A1 (en) 2006-09-28
EP1879596A1 (en) 2008-01-23
EP1879596A4 (en) 2009-01-21
US20090099140A1 (en) 2009-04-16
WO2006102647A1 (en) 2006-09-28
TW200738244A (en) 2007-10-16

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