JP2008538004A5 - - Google Patents
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- JP2008538004A5 JP2008538004A5 JP2008505419A JP2008505419A JP2008538004A5 JP 2008538004 A5 JP2008538004 A5 JP 2008538004A5 JP 2008505419 A JP2008505419 A JP 2008505419A JP 2008505419 A JP2008505419 A JP 2008505419A JP 2008538004 A5 JP2008538004 A5 JP 2008538004A5
- Authority
- JP
- Japan
- Prior art keywords
- anisotropy
- fluorophore
- chemical
- wavelength
- measured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 22
- 239000000126 substance Substances 0.000 claims 21
- 238000002866 fluorescence resonance energy transfer Methods 0.000 claims 9
- 230000010287 polarization Effects 0.000 claims 7
- 230000003993 interaction Effects 0.000 claims 6
- 230000005284 excitation Effects 0.000 claims 4
- 230000005855 radiation Effects 0.000 claims 4
- 230000027455 binding Effects 0.000 claims 3
- 238000005259 measurement Methods 0.000 claims 3
- 230000009870 specific binding Effects 0.000 claims 3
- 230000009897 systematic effect Effects 0.000 claims 3
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66842805P | 2005-04-04 | 2005-04-04 | |
| US60/668,428 | 2005-04-04 | ||
| US67884205P | 2005-05-06 | 2005-05-06 | |
| US60/678,842 | 2005-05-06 | ||
| PCT/US2006/012292 WO2006107864A1 (en) | 2005-04-04 | 2006-04-03 | Screening using polarization anisotropy in fret emissions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008538004A JP2008538004A (ja) | 2008-10-02 |
| JP2008538004A5 true JP2008538004A5 (https=) | 2009-05-21 |
| JP4921458B2 JP4921458B2 (ja) | 2012-04-25 |
Family
ID=37073796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008505419A Expired - Fee Related JP4921458B2 (ja) | 2005-04-04 | 2006-04-03 | Fret発光における偏光異方性を使用したスクリーニングの方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20060234279A1 (https=) |
| EP (1) | EP1866443A4 (https=) |
| JP (1) | JP4921458B2 (https=) |
| TW (1) | TW200704778A (https=) |
| WO (1) | WO2006107864A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4921458B2 (ja) * | 2005-04-04 | 2012-04-25 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | Fret発光における偏光異方性を使用したスクリーニングの方法 |
| JP5189301B2 (ja) * | 2007-03-12 | 2013-04-24 | オリンパス株式会社 | レーザー走査型顕微鏡 |
| ES2462759T3 (es) | 2008-10-01 | 2014-05-26 | Sherwin Hua | Sistema para estabilización de tornillo pedicular guiado por alambre de vertebras de la columna |
| US8568306B2 (en) | 2009-04-03 | 2013-10-29 | Mitchell A Hardenbrook | Surgical retractor system |
| US20120230918A1 (en) * | 2009-07-28 | 2012-09-13 | Hoffmann-La-Roche Inc. | Non-invasive in vivo optical imaging method |
| CN102859997B (zh) | 2010-03-26 | 2018-05-04 | 艾科星科技公司 | 多输入电视接收器 |
| EP3560445A1 (en) | 2010-03-30 | 2019-10-30 | Sherwin Hua | Systems for pedicle screw stabilization of spinal vertebrae |
| US8569254B2 (en) | 2010-12-10 | 2013-10-29 | National Yang Ming University | Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same |
| US20140099264A1 (en) | 2011-03-07 | 2014-04-10 | F. Hoffman-La Roche Ag | Means and methods for in vivo testing of therapeutic antibodies |
| JP6385060B2 (ja) | 2011-03-07 | 2018-09-05 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 治療的に活性な抗体のインビボにおける選択 |
| KR101167649B1 (ko) | 2011-04-20 | 2012-07-20 | 한국과학기술원 | 세포 환경 내에서의 단일 분자 수준의 단백질-단백질 상호작용 분석 장치 |
| US9746470B2 (en) * | 2011-05-09 | 2017-08-29 | Whitehead Institute For Biomedical Research | Chaperone interaction assays and uses thereof |
| JP5877741B2 (ja) * | 2012-03-16 | 2016-03-08 | 株式会社日立製作所 | 細胞数モニタリング方法 |
| WO2014059281A1 (en) * | 2012-10-11 | 2014-04-17 | The Regents Of The University Of Michigan | Fluorescence polarization assay for detecting high molecular weight molecules in biological fluids |
| CN102967554B (zh) * | 2012-10-29 | 2016-12-21 | 广东工业大学 | 一种双通道、单光路结构的荧光各向异性显微成像装置及方法 |
| LT3060677T (lt) * | 2013-10-25 | 2018-08-27 | Biomadison, Inc. | Fermentų tyrimo su dublikuotais fluoroforais būdas |
| ES2958398T3 (es) | 2015-01-23 | 2024-02-08 | Bayer Ag | Procedimiento y dispositivo para determinar el efecto de sustancias activas sobre nematodos y otros organismos en ensayos acuosos |
| CN109509509B (zh) * | 2018-09-29 | 2020-12-22 | 江西理工大学 | 基于动态加权蛋白质相互作用网络的蛋白质复合物挖掘方法 |
| US11160580B2 (en) | 2019-04-24 | 2021-11-02 | Spine23 Inc. | Systems and methods for pedicle screw stabilization of spinal vertebrae |
| EP4065016B1 (en) | 2019-11-27 | 2025-10-22 | Spine23 Inc. | Systems for treating a lateral curvature of a spine |
| US11782001B2 (en) | 2020-12-04 | 2023-10-10 | Attolight AG | Dislocation type and density discrimination in semiconductor materials using cathodoluminescence measurements |
| TWI808554B (zh) * | 2020-12-04 | 2023-07-11 | 亞光股份有限公司 | 使用陰極發光測量判別半導體材料中的位錯類型和密度的裝置與方法 |
| US12076058B2 (en) | 2021-05-12 | 2024-09-03 | Spine23 Inc. | Systems and methods for pedicle screw stabilization of spinal vertebrae |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5524405A (en) | 1994-02-28 | 1996-06-11 | Byrd; Randall | Wall structure |
| US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5597696A (en) * | 1994-07-18 | 1997-01-28 | Becton Dickinson And Company | Covalent cyanine dye oligonucleotide conjugates |
| US6573045B1 (en) * | 1998-06-05 | 2003-06-03 | Ribotargets, Ltd. | Methods and kits for discovery of RNA-binding compounds |
| EP1188057B1 (en) * | 1999-06-24 | 2008-01-23 | McMASTER UNIVERSITY | Incorporation and applications of biomolecular interactions within a carrier |
| US6509161B1 (en) * | 2000-02-29 | 2003-01-21 | Gentronix Limited | Green fluorescent protein |
| US6777184B2 (en) * | 2000-05-12 | 2004-08-17 | Caliper Life Sciences, Inc. | Detection of nucleic acid hybridization by fluorescence polarization |
| EP1409982A4 (en) * | 2001-06-14 | 2006-05-24 | Anadys Pharmaceuticals Inc | PROCESS FOR SCREENING ON LIGANDS OF TARGET MOLECULES |
| US20030228603A1 (en) * | 2002-04-05 | 2003-12-11 | Cload Sharon T. | Compositions selective for caffeine or aspartame and methods of using same |
| US20030228703A1 (en) | 2002-04-05 | 2003-12-11 | The Regents Of The University Of Michigan | Fluorescence resonance energy transfer quantitation and stoichiometry in living cells |
| US6713262B2 (en) * | 2002-06-25 | 2004-03-30 | Agilent Technologies, Inc. | Methods and compositions for high throughput identification of protein/nucleic acid binding pairs |
| JP2004093527A (ja) * | 2002-09-04 | 2004-03-25 | Center For Advanced Science & Technology Incubation Ltd | 蛍光共鳴エネルギー転移を用いた蛋白質の分析方法 |
| JP4214206B2 (ja) * | 2002-12-10 | 2009-01-28 | 独立行政法人理化学研究所 | Fretを利用した蛍光指示薬 |
| JP2007504445A (ja) | 2003-08-26 | 2007-03-01 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | 時間依存蛍光計測 |
| US20050264805A1 (en) | 2004-02-09 | 2005-12-01 | Blueshift Biotechnologies, Inc. | Methods and apparatus for scanning small sample volumes |
| FR2872287B1 (fr) * | 2004-06-28 | 2007-03-16 | Cis Bio Internat Sa | Procede d'amelioration de la detection des signaux de fluorescence lors d'un transfert d'energie non radiatif |
| JP2008505321A (ja) * | 2004-07-02 | 2008-02-21 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | 蛍光体微小環境の探索 |
| US8031338B2 (en) * | 2004-12-02 | 2011-10-04 | Vanderbilt University | Measuring Forster resonance energy transfer with polarized and depolarized light |
| JP4921458B2 (ja) * | 2005-04-04 | 2012-04-25 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | Fret発光における偏光異方性を使用したスクリーニングの方法 |
| JP5189301B2 (ja) * | 2007-03-12 | 2013-04-24 | オリンパス株式会社 | レーザー走査型顕微鏡 |
-
2006
- 2006-04-03 JP JP2008505419A patent/JP4921458B2/ja not_active Expired - Fee Related
- 2006-04-03 WO PCT/US2006/012292 patent/WO2006107864A1/en not_active Ceased
- 2006-04-03 EP EP06758259A patent/EP1866443A4/en not_active Withdrawn
- 2006-04-04 US US11/398,496 patent/US20060234279A1/en not_active Abandoned
- 2006-04-04 TW TW095111992A patent/TW200704778A/zh unknown
-
2008
- 2008-02-11 US US12/069,724 patent/US7674588B2/en not_active Expired - Fee Related
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