JP2008537930A5 - - Google Patents

Download PDF

Info

Publication number
JP2008537930A5
JP2008537930A5 JP2008500782A JP2008500782A JP2008537930A5 JP 2008537930 A5 JP2008537930 A5 JP 2008537930A5 JP 2008500782 A JP2008500782 A JP 2008500782A JP 2008500782 A JP2008500782 A JP 2008500782A JP 2008537930 A5 JP2008537930 A5 JP 2008537930A5
Authority
JP
Japan
Prior art keywords
alkyl
group
fluoro
optionally substituted
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008500782A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008537930A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/007717 external-priority patent/WO2006098912A1/en
Publication of JP2008537930A publication Critical patent/JP2008537930A/ja
Publication of JP2008537930A5 publication Critical patent/JP2008537930A5/ja
Withdrawn legal-status Critical Current

Links

JP2008500782A 2005-03-09 2006-03-03 ジフェニル置換シクロアルカン、前記化合物を含む組成物及び使用方法 Withdrawn JP2008537930A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65989805P 2005-03-09 2005-03-09
PCT/US2006/007717 WO2006098912A1 (en) 2005-03-09 2006-03-03 Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use

Publications (2)

Publication Number Publication Date
JP2008537930A JP2008537930A (ja) 2008-10-02
JP2008537930A5 true JP2008537930A5 (https=) 2009-04-09

Family

ID=36992014

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008500782A Withdrawn JP2008537930A (ja) 2005-03-09 2006-03-03 ジフェニル置換シクロアルカン、前記化合物を含む組成物及び使用方法

Country Status (7)

Country Link
US (1) US20090197883A1 (https=)
EP (1) EP1858513A4 (https=)
JP (1) JP2008537930A (https=)
CN (1) CN101137376A (https=)
AU (1) AU2006223508A1 (https=)
CA (1) CA2600860A1 (https=)
WO (1) WO2006098912A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006044602A2 (en) 2004-10-18 2006-04-27 Merck & Co., Inc. Diphenyl substituted alkanes as flap inhiibitors
US20090258885A1 (en) * 2005-11-04 2009-10-15 Armstrong Helen M Diphenylmethane Derivatives as Inhibitors of Leukotriene Biosynthesis
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
WO2007120574A2 (en) 2006-04-11 2007-10-25 Merck & Co., Inc. Diaryl substituted alkanes
ATE543810T1 (de) * 2006-09-01 2012-02-15 Merck Sharp & Dohme Hemmer des 5-lipoxygenase aktivierenden proteins (flap)
TW200920369A (en) 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
JP5324082B2 (ja) * 2007-12-20 2013-10-23 大阪瓦斯株式会社 9,9−ビス(カルボキシアリール)フルオレン類およびそのエステルの製造方法
JP5791500B2 (ja) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ,エルエルシー. 5−リポキシゲナーゼ活性化タンパク質阻害剤
JP2011529504A (ja) * 2008-07-28 2011-12-08 ギリアード サイエンシーズ, インコーポレイテッド シクロアルキリデンヒストン脱アセチル化酵素阻害剤化合物およびヘテロシクロアルキリデンヒストン脱アセチル化酵素阻害剤化合物
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
CA2774515A1 (en) * 2009-09-17 2011-03-24 Vanderbilt University Substituted phenylamine carboxamide analogs as mglur5 negative allosteric modulators and methods of making and using the same
TW201215607A (en) * 2010-07-02 2012-04-16 Lundbeck & Co As H Aryl-and heteroarylamid derivatives as PDE10A enzyme inhibitor
RU2013114390A (ru) 2010-08-31 2014-10-10 СНУ Ар энд ДиБи ФАУНДЕЙШН Применение фетального репрограммирования посредством ppar-дельта-агониста
AU2014353150A1 (en) 2013-11-19 2016-07-07 Vanderbilt University Substituted imidazopyridine and triazolopyridine compounds as negative allosteric modulators of mGluR5
US9533982B2 (en) 2014-03-20 2017-01-03 Vanderbilt University Substituted bicyclic heteroaryl carboxamide analogs as mGluR5 negative allosteric modulators
US9550778B2 (en) 2014-10-03 2017-01-24 Vanderbilt University Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5
US10500178B2 (en) 2015-03-13 2019-12-10 The Board Of Trustees Of The Leland Stanford Junior University LTB4 inhibition to prevent and treat human lymphedema
CN106008474A (zh) * 2016-04-23 2016-10-12 上海大学 N2选择性烯醇醚取代的三氮唑衍生物及其制备方法
US12037327B2 (en) * 2018-05-04 2024-07-16 Saint Louis University Compounds and methods targeting GPER for treatment of diseases associated with calcium

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW206220B (https=) * 1991-07-01 1993-05-21 Ciba Geigy Ag
US5691351A (en) * 1996-02-06 1997-11-25 Abbott Laboratories Bis-(Heteroarylmethoxyphenyl)cycloalkyl carboxylates as inhibitors of leukotriene biosynthesis
US6756400B2 (en) * 2000-08-31 2004-06-29 Theravance, Inc. Sodium channel modulators
WO2005009951A2 (en) * 2003-07-24 2005-02-03 Merck & Co., Inc. Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use

Similar Documents

Publication Publication Date Title
JP2008537930A5 (https=)
RU2320648C2 (ru) 4,6,7,13-замещенные производные 1-бензил-изохинолина и фармацевтическая композиция, обладающая ингибирующей активностью в отношении гфат
JP2018515525A5 (https=)
KR950704228A (ko) 선택적 포스포디에스테르가수분해효소 iv형(pde_iv) 저해제로서의 카테콜 디에테르(catecol diethers as selective pde_iv inhibitors)
JP2009505988A5 (https=)
JP2008520702A5 (https=)
JP2016505619A5 (https=)
JP2021535207A5 (https=)
JP2011520815A5 (https=)
JP2004534824A5 (https=)
WO2016097869A4 (en) Fused ring heteroaryl compounds and their use as trk inhibitors
JP2013510825A5 (https=)
JP2018520195A5 (https=)
JP2018520105A5 (https=)
JP2013532652A5 (https=)
JP2009532464A5 (https=)
JP2009534404A5 (https=)
JP2010511018A5 (https=)
JP2009534406A5 (https=)
JP2013508288A5 (https=)
JP2009525287A5 (https=)
CR20200418A (es) Inhibidores de orginasa y sus mètodos de uso antecedentes
WO2008148868A8 (en) Piperidine/piperazine derivatives
RU2006140989A (ru) 2-пиридилзамещенные имидазолы как ингибиторы рецепторов alk4
ME02355B (me) Derivati 2-0ks0-1-pirolidinil imidazotiadiazola