JP2008536815A - チオエーテル架橋を含む巨大分子 - Google Patents

チオエーテル架橋を含む巨大分子 Download PDF

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Publication number
JP2008536815A
JP2008536815A JP2008501999A JP2008501999A JP2008536815A JP 2008536815 A JP2008536815 A JP 2008536815A JP 2008501999 A JP2008501999 A JP 2008501999A JP 2008501999 A JP2008501999 A JP 2008501999A JP 2008536815 A JP2008536815 A JP 2008536815A
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JP
Japan
Prior art keywords
antibody
composition
antibodies
thioether
thioether bridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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JP2008501999A
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English (en)
Japanese (ja)
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JP2008536815A5 (enExample
Inventor
アイ． トウス グイルレルモ
スチェネルマン マルク
ウェイ ジピング
Original Assignee
メディミューン，エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by メディミューン，エルエルシー filed Critical メディミューン，エルエルシー
Publication of JP2008536815A publication Critical patent/JP2008536815A/ja
Publication of JP2008536815A5 publication Critical patent/JP2008536815A5/ja
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624—Disulfide-stabilized antibody (dsFv)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008501999A 2005-03-14 2006-03-14 チオエーテル架橋を含む巨大分子 Abandoned JP2008536815A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66172405P 2005-03-14 2005-03-14
US69913805P 2005-07-13 2005-07-13
PCT/US2006/009311 WO2006099481A2 (en) 2005-03-14 2006-03-14 Macromolecules comprising a thioether cross-link

Publications (2)

Publication Number Publication Date
JP2008536815A true JP2008536815A (ja) 2008-09-11
JP2008536815A5 JP2008536815A5 (enExample) 2009-05-21

Family

ID=36992404

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008501999A Abandoned JP2008536815A (ja) 2005-03-14 2006-03-14 チオエーテル架橋を含む巨大分子

Country Status (6)

Country Link
US (2) US7786273B2 (enExample)
EP (1) EP1858911A4 (enExample)
JP (1) JP2008536815A (enExample)
AU (1) AU2006223002A1 (enExample)
CA (1) CA2600844A1 (enExample)
WO (1) WO2006099481A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509483A (ja) * 2016-02-25 2019-04-04 ザ バインディング サイト グループ リミティド 質量分析キット

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009532027A (ja) * 2006-03-28 2009-09-10 バイオジェン・アイデック・エムエイ・インコーポレイテッド 抗ｉｇｆ−１ｒ抗体およびその使用
CA2697922A1 (en) * 2007-08-28 2009-03-12 Biogen Idec Ma Inc. Compositions that bind multiple epitopes of igf-1r
JP2010537985A (ja) * 2007-08-28 2010-12-09 バイオジェン アイデック マサチューセッツ インコーポレイテッド 抗ｉｇｆ−１ｒ抗体およびその使用
WO2009028639A1 (ja) 2007-08-30 2009-03-05 Daiichi Sankyo Company, Limited 抗ｅｐｈａ２抗体
BRPI0819063A2 (pt) 2007-11-27 2020-08-18 The University Of British Columbia método para tratamento de artrite, anticorpo, hibridoma, antagonista de 14-3-3, usos de um antagonista de 14-3-3, composições farmacêuticas, método para redução da expressão de mmp no sinóvio de um paciente e usos de uma composição farmacêutica
WO2009126304A1 (en) * 2008-04-11 2009-10-15 Biogen Idec Ma Inc. Therapeutic combinations of anti-igf-1r antibodies and other compounds
KR20150084836A (ko) * 2012-11-05 2015-07-22 메디뮨 엘엘씨 벤조나아제 부재 하의 시나지스 분리 방법
BR112017008383A2 (en) * 2014-10-31 2018-07-31 Medimmune, Llc improved production method
US20190048064A1 (en) * 2016-02-25 2019-02-14 The Binding Site Group Limited Antibodies
WO2018075954A2 (en) 2016-10-21 2018-04-26 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
AU2017345786B2 (en) 2016-10-21 2024-08-01 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
US11312761B2 (en) 2016-10-21 2022-04-26 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
GB201708262D0 (en) 2017-05-23 2017-07-05 Binding Site Group Ltd Assay for plasma cell associated disease
CN108017717B (zh) * 2018-01-24 2019-08-16 首都医科大学宣武医院 一种用于体外高效定向扩增的嵌合抗原受体及其应用
CN113166236A (zh) * 2018-09-21 2021-07-23 北卡罗来纳大学查佩尔希尔分校 限制穿过黏液的合成粘合剂
GB202007047D0 (en) 2020-05-13 2020-06-24 Binding Site Group Ltd Mass spectrometry controls
US20220268783A1 (en) * 2021-02-19 2022-08-25 Waters Technologies Corporation Methods for peptide mapping of adeno-associated virus (aav) proteins
IL328264A (en) 2023-11-14 2026-07-01 Janssen Pharmaceuticals Inc Anti-Respiratory Syncytial Virus Antibodies and Their Uses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003493A1 (en) * 1989-08-29 1991-03-21 The University Of Southampton Bi-or trispecific (fab)3 or (fab)4 conjugates
US5091542A (en) * 1990-03-09 1992-02-25 Hybritech Incorporated Tris-maleimido compounds as intermediates in trifunctional antibody synthesis
AU664855B2 (en) * 1991-08-09 1995-12-07 Winfried Kolbeck Lanthionine bridged peptides
US6897044B1 (en) * 1999-01-28 2005-05-24 Biogen Idec, Inc. Production of tetravalent antibodies
ATE328582T1 (de) * 1999-04-23 2006-06-15 Mitsubishi Chem Corp Antikörper und polyalkylenglycol gebundenes liposom
US20060123504A1 (en) * 2004-12-07 2006-06-08 Avigenics, Inc. Methods of producing polyclonal antibodies
US20060286548A1 (en) * 2005-06-16 2006-12-21 Gregory Liposky Method of making recombinant human antibodies for use in biosensor technology

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509483A (ja) * 2016-02-25 2019-04-04 ザ バインディング サイト グループ リミティド 質量分析キット

Also Published As

Publication number Publication date
EP1858911A2 (en) 2007-11-28
WO2006099481A2 (en) 2006-09-21
CA2600844A1 (en) 2006-09-21
WO2006099481A3 (en) 2007-04-19
US20090030187A1 (en) 2009-01-29
AU2006223002A1 (en) 2006-09-21
US20060216284A1 (en) 2006-09-28
EP1858911A4 (en) 2009-12-16
US7786273B2 (en) 2010-08-31

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