CA2600844A1 - Macromolecules comprising a thioether cross-link - Google Patents

Macromolecules comprising a thioether cross-link Download PDF

Info

Publication number
CA2600844A1
CA2600844A1 CA002600844A CA2600844A CA2600844A1 CA 2600844 A1 CA2600844 A1 CA 2600844A1 CA 002600844 A CA002600844 A CA 002600844A CA 2600844 A CA2600844 A CA 2600844A CA 2600844 A1 CA2600844 A1 CA 2600844A1
Authority
CA
Canada
Prior art keywords
antibody
antibodies
composition
link
thioether cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002600844A
Other languages
English (en)
French (fr)
Inventor
Guillermo I. Tous
Mark Schenerman
Ziping Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedImmune LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2600844A1 publication Critical patent/CA2600844A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624Disulfide-stabilized antibody (dsFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002600844A 2005-03-14 2006-03-14 Macromolecules comprising a thioether cross-link Abandoned CA2600844A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66172405P 2005-03-14 2005-03-14
US60/661,724 2005-03-14
US69913805P 2005-07-13 2005-07-13
US60/699,138 2005-07-13
PCT/US2006/009311 WO2006099481A2 (en) 2005-03-14 2006-03-14 Macromolecules comprising a thioether cross-link

Publications (1)

Publication Number Publication Date
CA2600844A1 true CA2600844A1 (en) 2006-09-21

Family

ID=36992404

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002600844A Abandoned CA2600844A1 (en) 2005-03-14 2006-03-14 Macromolecules comprising a thioether cross-link

Country Status (6)

Country Link
US (2) US7786273B2 (enExample)
EP (1) EP1858911A4 (enExample)
JP (1) JP2008536815A (enExample)
AU (1) AU2006223002A1 (enExample)
CA (1) CA2600844A1 (enExample)
WO (1) WO2006099481A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG170799A1 (en) * 2006-03-28 2011-05-30 Biogen Idec Inc Anti-igf-ir antibodies and uses thereof
CN101842116A (zh) * 2007-08-28 2010-09-22 比奥根艾迪克Ma公司 结合igf-1r多个表位的组合物
CN101842117A (zh) * 2007-08-28 2010-09-22 比奥根艾迪克Ma公司 抗igf-1r抗体及其用途
BRPI0816094A2 (pt) 2007-08-30 2015-03-03 Daiichi Sankyo Co Ltd Anticorpo, polipeptídeo, hibridoma, composição farmacêutica, método para inibir o desenvolvimento de tumor em um mamífero, polinucleotídeo, célula hospedeira, e, método para produzir um anticorpo.
KR20180102215A (ko) 2007-11-27 2018-09-14 더 유니버시티 오브 브리티쉬 콜롬비아 관절염의 진단과 치료를 위한 14-3-3 에타 항체 및 이의 용도
WO2009126304A1 (en) * 2008-04-11 2009-10-15 Biogen Idec Ma Inc. Therapeutic combinations of anti-igf-1r antibodies and other compounds
CN104854125A (zh) * 2012-11-05 2015-08-19 米迪缪尼有限公司 在不存在全能核酸酶的情况下分离synagis*的方法
EP3212510B1 (en) * 2014-10-31 2020-12-09 Medlmmune, LLC Manufacturing method of a degassed composition
AU2017222402B2 (en) * 2016-02-25 2024-02-01 The Binding Site Group Limited Antibodies
GB201603291D0 (en) 2016-02-25 2016-04-13 Binding Site Group The Ltd Antibodies
EP3974447A3 (en) 2016-10-21 2022-09-07 Adimab, LLC Anti-respiratory syncytial virus antibodies, and methods of their generation and use
US11479600B2 (en) 2016-10-21 2022-10-25 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
SG11201903287PA (en) 2016-10-21 2019-05-30 Adimab Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
GB201708262D0 (en) 2017-05-23 2017-07-05 Binding Site Group Ltd Assay for plasma cell associated disease
CN108017717B (zh) * 2018-01-24 2019-08-16 首都医科大学宣武医院 一种用于体外高效定向扩增的嵌合抗原受体及其应用
GB202007047D0 (en) 2020-05-13 2020-06-24 Binding Site Group Ltd Mass spectrometry controls
EP4295158A1 (en) * 2021-02-19 2023-12-27 Waters Technologies Corporation Methods for peptide mapping of adeno-associated virus (aav) proteins
WO2025104604A1 (en) 2023-11-14 2025-05-22 Janssen Pharmaceuticals, Inc. Anti-respiratory syncytial virus antibodies and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003493A1 (en) * 1989-08-29 1991-03-21 The University Of Southampton Bi-or trispecific (fab)3 or (fab)4 conjugates
US5091542A (en) 1990-03-09 1992-02-25 Hybritech Incorporated Tris-maleimido compounds as intermediates in trifunctional antibody synthesis
JP3407260B2 (ja) * 1991-08-09 2003-05-19 コルベツク,ヴインフリート ランチオニン架橋ペプチド
US6897044B1 (en) 1999-01-28 2005-05-24 Biogen Idec, Inc. Production of tetravalent antibodies
CA2370043A1 (en) * 1999-04-23 2000-11-02 Mitsubishi Chemical Corporation Liposome bonded with antibody and polyalkylene glycol
US20060123504A1 (en) * 2004-12-07 2006-06-08 Avigenics, Inc. Methods of producing polyclonal antibodies
US20060286548A1 (en) * 2005-06-16 2006-12-21 Gregory Liposky Method of making recombinant human antibodies for use in biosensor technology

Also Published As

Publication number Publication date
WO2006099481A3 (en) 2007-04-19
JP2008536815A (ja) 2008-09-11
US20060216284A1 (en) 2006-09-28
US7786273B2 (en) 2010-08-31
EP1858911A2 (en) 2007-11-28
EP1858911A4 (en) 2009-12-16
US20090030187A1 (en) 2009-01-29
AU2006223002A1 (en) 2006-09-21
WO2006099481A2 (en) 2006-09-21

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20110314