JP2008534541A5 - - Google Patents
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- Publication number
- JP2008534541A5 JP2008534541A5 JP2008503415A JP2008503415A JP2008534541A5 JP 2008534541 A5 JP2008534541 A5 JP 2008534541A5 JP 2008503415 A JP2008503415 A JP 2008503415A JP 2008503415 A JP2008503415 A JP 2008503415A JP 2008534541 A5 JP2008534541 A5 JP 2008534541A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- cycloalkyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05006939 | 2005-03-30 | ||
| PCT/EP2006/002769 WO2006103038A1 (en) | 2005-03-30 | 2006-03-27 | Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008534541A JP2008534541A (ja) | 2008-08-28 |
| JP2008534541A5 true JP2008534541A5 (https=) | 2009-05-14 |
Family
ID=36545049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503415A Pending JP2008534541A (ja) | 2005-03-30 | 2006-03-27 | 置換１，２−エチレンジアミン、前記化合物を含む薬物、それらの使用及びそれらの製造方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7713961B2 (https=) |
| EP (1) | EP1866034A1 (https=) |
| JP (1) | JP2008534541A (https=) |
| AR (1) | AR056862A1 (https=) |
| CA (1) | CA2603404A1 (https=) |
| TW (1) | TW200716152A (https=) |
| WO (1) | WO2006103038A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2603404A1 (en) * | 2005-03-30 | 2006-10-05 | Boehringer Ingelheim International Gmbh | Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture |
| CA2617294A1 (en) * | 2005-08-03 | 2007-02-08 | Boehringer Ingelheim International Gmbh | Substituted ethane-1,2-diamines for the treatment of alzheimer's disease ii |
| US20100144681A1 (en) * | 2005-08-11 | 2010-06-10 | Klaus Fuchs | Compounds for the treatment of alzheimer's disease |
| EP1915339A1 (de) * | 2005-08-11 | 2008-04-30 | Boehringer Ingelheim International GmbH | Inhibitoren der beta-sekretase zur behandlung der alzheimer- erkrankung |
| CA2618019A1 (en) * | 2005-08-11 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Compounds for the treatment of alzheimer's disease |
| WO2007017510A2 (de) * | 2005-08-11 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Isophthalsäurediamide zur behandlung der alzheimer erkrankung |
| WO2010042796A1 (en) | 2008-10-10 | 2010-04-15 | Purdue Research Foundation | Compounds for treatment of alzheimer's disease |
| US8394807B2 (en) | 2008-11-20 | 2013-03-12 | Purdue Research Foundation | Quinazoline inhibitors of BACE 1 and methods of using |
| WO2010065861A2 (en) * | 2008-12-05 | 2010-06-10 | Purdue Research Foundation | Inhibitors of bace 1 and methods for treating alzheimer's disease |
| US20130059840A1 (en) * | 2009-10-05 | 2013-03-07 | Comentis, Inc. | Sulfonamido pyrrolidine compounds which inhibit beta-secretase activity and methods of use thereof |
| WO2014036105A2 (en) * | 2012-08-30 | 2014-03-06 | Oklahoma Medical Research Foundation | Inhibitors of memapsin 2 cleavage for the treatment of alzheimer's disease |
| BR112023026747A2 (pt) | 2021-06-18 | 2024-03-12 | Aligos Therapeutics Inc | Métodos e composições para direcionamento de pd-l1 |
| CA3240346A1 (en) | 2021-12-16 | 2023-06-22 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ264143A (en) | 1993-08-09 | 1996-11-26 | Lilly Co Eli | Use of an aspartyl protease inhibitor to inhibit beta-amyloid peptide production |
| US7087399B1 (en) | 1999-05-13 | 2006-08-08 | Scios, Inc. | β-secretase and modulation of β-secretase activity |
| EP1196609A2 (en) | 1999-06-28 | 2002-04-17 | Oklahoma Medical Research Foundation | Catalytically active recombinant memapsin and methods of use thereof |
| MXPA03011399A (es) * | 2001-06-08 | 2004-07-01 | Elan Pharm Inc | Metodos para tratar la enfermedad de alzheimer. |
| EP1453516A2 (de) | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
| JP2005534614A (ja) * | 2002-01-04 | 2005-11-17 | イーラン ファーマスーティカルズ、インコーポレイテッド | アルツハイマー病治療のための置換アミノカルボキサミド |
| AU2003299101A1 (en) * | 2002-09-27 | 2004-04-19 | Elan Pharmaceuticals, Inc. | Compounds for the treatment of alzheimer's disease |
| CA2505098A1 (en) * | 2002-11-12 | 2004-05-27 | Merck & Co., Inc. | Phenylcarboxamide beta-secretase inhibitors for the treatment of alzheimer's disease |
| US20050090449A1 (en) | 2003-05-13 | 2005-04-28 | Boehringer Ingelheim International Gmbh | Novel statine derivatives for the treatment of Alzheimer's disease |
| CN100430377C (zh) * | 2003-06-30 | 2008-11-05 | 麦克公司 | 用于治疗阿尔茨海默病的N-烷基苯基甲酰胺β分泌酶抑制剂 |
| WO2005110422A2 (en) | 2004-05-19 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Treatment of diseases associated with altered level of amyloid beta peptides |
| WO2005113582A1 (en) | 2004-05-22 | 2005-12-01 | Boehringer Ingelheim International Gmbh | Substituted ethane-1,2-diamines for the treatment of alzheimer's disease |
| WO2006050862A1 (en) | 2004-11-10 | 2006-05-18 | Boehringer Ingelheim International Gmbh | Statine derivatives for the treatment of alzheimer's disease |
| WO2006050861A2 (en) | 2004-11-10 | 2006-05-18 | Boehringer Ingelheim International Gmbh | Statine derivatives for the treatment of alzheimer's disease |
| CA2603404A1 (en) * | 2005-03-30 | 2006-10-05 | Boehringer Ingelheim International Gmbh | Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture |
| CA2617294A1 (en) | 2005-08-03 | 2007-02-08 | Boehringer Ingelheim International Gmbh | Substituted ethane-1,2-diamines for the treatment of alzheimer's disease ii |
| CA2618019A1 (en) | 2005-08-11 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Compounds for the treatment of alzheimer's disease |
-
2006
- 2006-03-27 CA CA002603404A patent/CA2603404A1/en not_active Abandoned
- 2006-03-27 JP JP2008503415A patent/JP2008534541A/ja active Pending
- 2006-03-27 WO PCT/EP2006/002769 patent/WO2006103038A1/en not_active Ceased
- 2006-03-27 EP EP06723747A patent/EP1866034A1/en not_active Withdrawn
- 2006-03-29 TW TW095110860A patent/TW200716152A/zh unknown
- 2006-03-29 AR ARP060101206A patent/AR056862A1/es not_active Application Discontinuation
- 2006-03-30 US US11/278,059 patent/US7713961B2/en active Active
-
2009
- 2009-07-29 US US12/511,474 patent/US20090325940A1/en not_active Abandoned
-
2010
- 2010-04-13 US US12/759,167 patent/US20100204160A1/en not_active Abandoned
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