JP2008531719A5 - - Google Patents
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- Publication number
- JP2008531719A5 JP2008531719A5 JP2007558223A JP2007558223A JP2008531719A5 JP 2008531719 A5 JP2008531719 A5 JP 2008531719A5 JP 2007558223 A JP2007558223 A JP 2007558223A JP 2007558223 A JP2007558223 A JP 2007558223A JP 2008531719 A5 JP2008531719 A5 JP 2008531719A5
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- JP
- Japan
- Prior art keywords
- composition
- antibody
- seq
- amino acids
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000012634 fragment Substances 0.000 claims 22
- 150000001413 amino acids Chemical class 0.000 claims 20
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 241000124008 Mammalia Species 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 5
- 229940124597 therapeutic agent Drugs 0.000 claims 5
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 3
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 3
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 claims 3
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 3
- 230000001404 mediated effect Effects 0.000 claims 3
- 206010003645 Atopy Diseases 0.000 claims 2
- 102100034459 Hepatitis A virus cellular receptor 1 Human genes 0.000 claims 2
- 101710185991 Hepatitis A virus cellular receptor 1 homolog Proteins 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 101001068136 Homo sapiens Hepatitis A virus cellular receptor 1 Proteins 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 1
- 102000051539 human HAVCR1 Human genes 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65778905P | 2005-03-02 | 2005-03-02 | |
| PCT/US2006/007441 WO2006094134A2 (en) | 2005-03-02 | 2006-03-02 | Kim-1 antibodies for treatment of th2-mediated conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012073852A Division JP2012131825A (ja) | 2005-03-02 | 2012-03-28 | Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008531719A JP2008531719A (ja) | 2008-08-14 |
| JP2008531719A5 true JP2008531719A5 (cg-RX-API-DMAC7.html) | 2009-03-26 |
Family
ID=36648475
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007558223A Withdrawn JP2008531719A (ja) | 2005-03-02 | 2006-03-02 | Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 |
| JP2012073852A Pending JP2012131825A (ja) | 2005-03-02 | 2012-03-28 | Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012073852A Pending JP2012131825A (ja) | 2005-03-02 | 2012-03-28 | Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8206705B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1865985B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2008531719A (cg-RX-API-DMAC7.html) |
| KR (1) | KR101213894B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN101166542A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE478707T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2006218489B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0608254A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2599967C (cg-RX-API-DMAC7.html) |
| DE (1) | DE602006016413D1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL185653A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ562045A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006094134A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200708372B (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008064031A2 (en) * | 2006-11-13 | 2008-05-29 | Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services | Potent activation of antigen presenting cells by the hepatitis a virus cellular receptor 1 and its role in the regulation of immune responses |
| CA2833785C (en) | 2011-04-21 | 2022-06-07 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for the treatment of neuromyelitis optica |
| MA43135A (fr) | 2015-10-30 | 2018-09-05 | Aleta Biotherapeutics Inc | Compositions et méthodes pour le du traitement du cancer |
| BR112018008390A2 (pt) | 2015-10-30 | 2018-11-27 | Aleta Biotherapeutics Inc | composições e métodos para transdução tumoral |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2, Inc., Danville, Calif. | Geänderte antikörper. |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| DK0590058T3 (da) | 1991-06-14 | 2004-03-29 | Genentech Inc | Humaniseret heregulin-antistof |
| ATE182625T1 (de) | 1993-01-12 | 1999-08-15 | Biogen Inc | Rekombinante anti-vla4 antikörpermoleküle |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| US5622861A (en) | 1994-08-05 | 1997-04-22 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA encoding hepatitis A virus receptor |
| US6066322A (en) | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DE19541844C1 (de) | 1995-11-09 | 1997-07-24 | Gsf Forschungszentrum Umwelt | Verfahren zur Herstellung von menschlichen Antikörpern und deren Verwendung |
| US6165733A (en) | 1996-05-23 | 2000-12-26 | Chiron Corporation | γ II adaptin |
| CN1147584C (zh) | 1996-05-24 | 2004-04-28 | 拜奥根有限公司 | 组织再生调节物 |
| JP2001503271A (ja) | 1996-11-01 | 2001-03-13 | ヒューマン ジノーム サイエンシーズ，インコーポレイテッド | ヒト粘膜アドレシン細胞接着分子―１（ＭＡｄＣＡＭ―１）およびそのスプライス変異体 |
| EP2305027B1 (en) | 1996-12-03 | 2014-07-02 | Amgen Fremont Inc. | Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom |
| CA2274250A1 (en) | 1996-12-06 | 1998-06-11 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1.beta. converting enzyme |
| CN101274962A (zh) | 1998-01-23 | 2008-10-01 | 霍夫曼-拉罗奇有限公司 | 人il-12抗体 |
| KR20010041765A (ko) | 1998-03-11 | 2001-05-25 | 가마쿠라 아키오 | ＩｇＥ 항체생산 억제제 및 자기면역질환 억제제 |
| US6228642B1 (en) | 1998-10-05 | 2001-05-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of tumor necrosis factor-(α) (TNF-α) expression |
| US8288322B2 (en) | 2000-04-17 | 2012-10-16 | Dyax Corp. | Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries |
| ATE425249T1 (de) | 2000-06-16 | 2009-03-15 | Biogen Idec Inc | Renale regulatorische elemente und deren verwendung |
| EP1401869B1 (en) * | 2001-06-01 | 2007-12-26 | Biogen Idec MA Inc. | Molecules and methods for inhibiting shedding of kim-1 |
| US7838220B2 (en) | 2001-06-29 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes associated with immune disease |
| US7553939B2 (en) | 2001-06-29 | 2009-06-30 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes and methods of use thereof |
| EP1434881A4 (en) | 2001-09-17 | 2005-10-26 | Protein Design Labs Inc | METHOD FOR DIAGNOSIS OF CANCER COMPOSITIONS AND METHOD FOR SCREENING ON CANCER MODULATORS |
| WO2003042661A2 (en) | 2001-11-13 | 2003-05-22 | Protein Design Labs, Inc. | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer |
| US7687454B2 (en) | 2001-12-03 | 2010-03-30 | The University Of British Columbia | Effectors of innate immunity determination |
| WO2003063792A2 (en) | 2002-01-30 | 2003-08-07 | The Brigham And Women's Hospital, Inc. | Compositions and methods related to tim-3, a th1-specific cell surface molecule |
| US20050014687A1 (en) | 2002-03-19 | 2005-01-20 | Anderson David W. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| GB0215509D0 (en) | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
| DE60322744D1 (de) | 2002-12-30 | 2008-09-18 | Biogen Idec Inc | Kim-1-antagonisten und verwendung zur immunsystemmodulation |
| EP3000886A1 (en) * | 2003-03-19 | 2016-03-30 | Amgen Fremont Inc. | Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof |
| WO2005001092A2 (en) | 2003-05-20 | 2005-01-06 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| TW200539890A (en) | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
| CA2560941A1 (en) | 2004-03-24 | 2005-10-20 | Telos Pharmaceuticals Llc | Compositions as adjuvants to improve immune responses to vaccines and methods of use |
| US8025557B2 (en) | 2009-02-27 | 2011-09-27 | Illinois Tool Works Inc. | Sanding clay |
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2006
- 2006-03-02 AU AU2006218489A patent/AU2006218489B2/en not_active Ceased
- 2006-03-02 CN CNA2006800139893A patent/CN101166542A/zh active Pending
- 2006-03-02 KR KR1020077022608A patent/KR101213894B1/ko not_active Expired - Fee Related
- 2006-03-02 US US11/817,638 patent/US8206705B2/en not_active Expired - Fee Related
- 2006-03-02 NZ NZ562045A patent/NZ562045A/en not_active IP Right Cessation
- 2006-03-02 EP EP06736714A patent/EP1865985B1/en active Active
- 2006-03-02 CA CA2599967A patent/CA2599967C/en not_active Expired - Fee Related
- 2006-03-02 CN CN201410043208.1A patent/CN103751780A/zh active Pending
- 2006-03-02 EP EP10173620.5A patent/EP2251037B1/en not_active Not-in-force
- 2006-03-02 WO PCT/US2006/007441 patent/WO2006094134A2/en not_active Ceased
- 2006-03-02 BR BRPI0608254-8A patent/BRPI0608254A2/pt not_active IP Right Cessation
- 2006-03-02 JP JP2007558223A patent/JP2008531719A/ja not_active Withdrawn
- 2006-03-02 AT AT06736714T patent/ATE478707T1/de not_active IP Right Cessation
- 2006-03-02 DE DE602006016413T patent/DE602006016413D1/de active Active
-
2007
- 2007-09-02 IL IL185653A patent/IL185653A/en not_active IP Right Cessation
- 2007-10-01 ZA ZA200708372A patent/ZA200708372B/xx unknown
-
2011
- 2011-05-24 AU AU2011202405A patent/AU2011202405B2/en not_active Ceased
-
2012
- 2012-03-28 JP JP2012073852A patent/JP2012131825A/ja active Pending
- 2012-04-04 US US13/439,413 patent/US20130089539A1/en not_active Abandoned