JP2008530242A5 - - Google Patents
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- Publication number
- JP2008530242A5 JP2008530242A5 JP2007556366A JP2007556366A JP2008530242A5 JP 2008530242 A5 JP2008530242 A5 JP 2008530242A5 JP 2007556366 A JP2007556366 A JP 2007556366A JP 2007556366 A JP2007556366 A JP 2007556366A JP 2008530242 A5 JP2008530242 A5 JP 2008530242A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- group
- alkyl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN347DE2005 | 2005-02-17 | ||
| IN347/DEL/2005 | 2005-02-17 | ||
| US11/096,718 US7521465B2 (en) | 2003-01-17 | 2005-03-31 | Diphenyl ether derivatives |
| US11/096,718 | 2005-03-31 | ||
| PCT/US2006/005846 WO2006089225A1 (en) | 2005-02-17 | 2006-02-17 | 5- [4- (4- (2 -amino- 2 -methoxycarbonylethyl) phenoxy) benzilidene] thiazolidin-2 , 4-dion e derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008530242A JP2008530242A (ja) | 2008-08-07 |
| JP2008530242A5 true JP2008530242A5 (OSRAM) | 2009-04-16 |
| JP5134974B2 JP5134974B2 (ja) | 2013-01-30 |
Family
ID=36570583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007556366A Expired - Fee Related JP5134974B2 (ja) | 2005-02-17 | 2006-02-17 | 血漿中のグルコースレベル、コレステロールレベル及びトリグリセリドレベルを低下させるための5−[4−(4−(2−アミノ−2−メトキシカルボニルエチル)フェノキシ)ベンジリデン]チアゾリジン−2,4−ジオン誘導体及び関連化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7521465B2 (OSRAM) |
| EP (1) | EP1848700B1 (OSRAM) |
| JP (1) | JP5134974B2 (OSRAM) |
| KR (1) | KR20070105364A (OSRAM) |
| CA (1) | CA2598087C (OSRAM) |
| ES (1) | ES2566337T3 (OSRAM) |
| HU (1) | HUE028882T2 (OSRAM) |
| PL (1) | PL1848700T3 (OSRAM) |
| WO (1) | WO2006089225A1 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9969980B2 (en) * | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US9969977B2 (en) * | 2002-09-20 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US7781464B2 (en) * | 2003-01-17 | 2010-08-24 | Bexel Pharmaceuticals, Inc. | Heterocyclic diphenyl ethers |
| US7521465B2 (en) | 2003-01-17 | 2009-04-21 | Bexel Pharmaceuticals, Inc. | Diphenyl ether derivatives |
| US7087576B2 (en) * | 2003-10-07 | 2006-08-08 | Bexel Pharmaceuticals, Inc. | Dipeptide phenyl ethers |
| KR100814109B1 (ko) * | 2006-01-09 | 2008-03-14 | 한국생명공학연구원 | 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물 |
| WO2008019306A2 (en) * | 2006-08-04 | 2008-02-14 | Decode Genetics Ehf | Aryl amino acid derivatives as inhibitors of lta4h (leukotriene a4 hydrolase) for treating inflammation |
| US20090069313A1 (en) * | 2007-09-06 | 2009-03-12 | Orchid Research Laboratories Ltd. | Novel MAO-A inhibitors |
| AU2009249314A1 (en) | 2008-05-20 | 2009-11-26 | Merck Sharp & Dohme Corp. | Efficient production of heterologous proteins using mannosyl transferase inhibitors |
| JP5957452B2 (ja) * | 2010-07-28 | 2016-07-27 | オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド | 肝臓、肺の障害、糖尿病合併症および心血管疾患の処置のためのジフェニルエーテル化合物 |
| US9056862B2 (en) | 2011-05-10 | 2015-06-16 | National University Corporation Kobe University | Thioxothiazolidine derivative having Ras function inhibitory effect |
| EP3221299A1 (en) | 2014-11-21 | 2017-09-27 | BSIM2 Biomolecular Simulations Lda. | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof |
| TW202019923A (zh) * | 2018-07-16 | 2020-06-01 | 義大利商吉斯藥品公司 | 作為Rho-激酶抑制劑之酪胺酸醯胺衍生物 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0228168A (ja) * | 1988-04-14 | 1990-01-30 | Sankyo Co Ltd | チアゾール誘導体 |
| US20020049240A1 (en) * | 1994-12-19 | 2002-04-25 | Beecham Group P.1.C. | Novel compounds |
| US5166137A (en) * | 1991-03-27 | 1992-11-24 | Nobipols Forskningsstiftelse | Guluronic acid polymers and use of same for inhibition of cytokine production |
| US5441971A (en) * | 1991-04-11 | 1995-08-15 | The Upjohn Company | Thiazolidinedione derivatives, production and use thereof |
| TW268952B (OSRAM) * | 1993-02-26 | 1996-01-21 | Takeda Pharm Industry Co Ltd | |
| US5527546A (en) * | 1994-08-10 | 1996-06-18 | Bayer Corporation | Human interleukin 6 inhibitor |
| RU2205874C2 (ru) * | 1995-05-11 | 2003-06-10 | Апплайд Резеч Системз Арс Холдинг Н.В. | Нуклеотидная последовательность, способная ингибировать активность il-6, плазмидный вектор для трансфекции в клетки млекопитающих, нуклеотидная последовательность, используемая при терапии, фармацевтическая композиция (варианты) |
| TW577875B (en) * | 1997-01-31 | 2004-03-01 | Shionogi & Co | Pyrrolidine derivatives with inhibitory activity for phospholipase A2 |
| US6331633B1 (en) * | 1998-05-08 | 2001-12-18 | Calyx Therapeutics Inc. | Heterocyclic analogs of diphenylethylene compounds |
| US6699896B1 (en) * | 1998-05-12 | 2004-03-02 | Wyeth | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| IL140084A0 (en) * | 1998-06-05 | 2002-02-10 | Astra Ab | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| WO2000000194A1 (en) * | 1998-06-27 | 2000-01-06 | Photogenesis, Inc. | Ophthalmic uses of ppargamma agonists and ppargamma antagonists |
| KR100613175B1 (ko) * | 1998-08-27 | 2006-08-17 | 오노 야꾸힝 고교 가부시키가이샤 | 카르복실산 유도체 및 그 유도체를 유효 성분으로서함유하는 약제 |
| BR0009594A (pt) * | 1999-04-07 | 2002-06-04 | Sankyo Co | Composto derivado de amina ou um seu sal farmacologicamente aceitável, fármaco, agente de melhoria da tolerância a insulina, agente de abaixamento do açúcar no sangue, agente imunorregulador, agente inibidor de aldose-redutase, agente inibidor de 5-lipoxigenase, agente inibidor da formação de peróxido lipìdico, agente de ativação de ppar, agente de antiosteoporose, agente antagonista de leucotrieno, agente promotor de célula gordurosa, agente inibidor da proliferação de célula cancerosa ou agente antagonista de cálcio, composição farmacêutica e uso de um composto |
| EE200100556A (et) | 1999-04-28 | 2003-02-17 | Aventis Pharma Deutschland Gmbh | Diarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi kasutamine ravimite valmistamiseks |
| TWI284533B (en) * | 1999-05-24 | 2007-08-01 | Sankyo Co | Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant |
| KR20010099634A (ko) | 1999-07-01 | 2001-11-09 | 할리 켈빈 비. | 텔로머라제 저해제 및 그 사용 방법 |
| ATE296294T1 (de) * | 1999-08-23 | 2005-06-15 | Kyorin Seiyaku Kk | Substituierte benzylthiazolidin-2,4-dion-derivate |
| AU6949900A (en) * | 1999-08-31 | 2001-03-26 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| JP2001199888A (ja) * | 2000-01-24 | 2001-07-24 | Fujimoto Brothers:Kk | 糖尿病治療剤 |
| JP2001308814A (ja) | 2000-04-19 | 2001-11-02 | Hitachi Ltd | フレーム構成自動識別通信装置 |
| US6620830B2 (en) * | 2000-04-21 | 2003-09-16 | Pfizer, Inc. | Thyroid receptor ligands |
| ATE310733T1 (de) | 2000-04-21 | 2005-12-15 | Pfizer Prod Inc | Thyroid-rezeptorliganden |
| US6680387B2 (en) | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6525202B2 (en) * | 2000-07-17 | 2003-02-25 | Wyeth | Cyclic amine phenyl beta-3 adrenergic receptor agonists |
| MXPA04002404A (es) | 2001-09-14 | 2004-05-31 | Novo Nordisk As | Ligandos novedosos para los sitios hisb10zn2+ del hexamero de insulina en estado r. |
| EP1456187A4 (en) * | 2001-11-15 | 2005-02-09 | Incyte San Diego Inc | N-SUBSTITUTED HETEROCYCLES FOR THE TREATMENT OF HYPERCHOLESTERINEMIA, DYSLIPIDEMIA AND OTHER METABOLIC DISORDER, CANCER AND OTHER DISEASES |
| US6794401B2 (en) | 2003-01-17 | 2004-09-21 | Bexel Pharmaceuticals, Inc. | Amino acid phenoxy ethers |
| US7521465B2 (en) | 2003-01-17 | 2009-04-21 | Bexel Pharmaceuticals, Inc. | Diphenyl ether derivatives |
| AU2004218808A1 (en) | 2003-03-11 | 2004-09-23 | Novo Nordisk A/S | Pharmaceutical preparations comprising acid-stabilised insulin |
| US7087576B2 (en) * | 2003-10-07 | 2006-08-08 | Bexel Pharmaceuticals, Inc. | Dipeptide phenyl ethers |
-
2005
- 2005-03-31 US US11/096,718 patent/US7521465B2/en not_active Expired - Fee Related
-
2006
- 2006-02-17 KR KR1020077021343A patent/KR20070105364A/ko not_active Ceased
- 2006-02-17 JP JP2007556366A patent/JP5134974B2/ja not_active Expired - Fee Related
- 2006-02-17 HU HUE06735487A patent/HUE028882T2/en unknown
- 2006-02-17 PL PL06735487T patent/PL1848700T3/pl unknown
- 2006-02-17 CA CA2598087A patent/CA2598087C/en not_active Expired - Fee Related
- 2006-02-17 ES ES06735487.8T patent/ES2566337T3/es active Active
- 2006-02-17 WO PCT/US2006/005846 patent/WO2006089225A1/en not_active Ceased
- 2006-02-17 EP EP06735487.8A patent/EP1848700B1/en not_active Not-in-force
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