JP2008524329A5 - - Google Patents
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- Publication number
- JP2008524329A5 JP2008524329A5 JP2007548319A JP2007548319A JP2008524329A5 JP 2008524329 A5 JP2008524329 A5 JP 2008524329A5 JP 2007548319 A JP2007548319 A JP 2007548319A JP 2007548319 A JP2007548319 A JP 2007548319A JP 2008524329 A5 JP2008524329 A5 JP 2008524329A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- mammal
- pharmaceutically acceptable
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 208000010507 Adenocarcinoma of Lung Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000031671 Large B-Cell Diffuse Lymphoma Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010041067 Small cell lung cancer Diseases 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 201000005249 lung adenocarcinoma Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 201000006845 reticulosarcoma Diseases 0.000 claims 1
- 208000029922 reticulum cell sarcoma Diseases 0.000 claims 1
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 1
- 230000020347 spindle assembly Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63772204P | 2004-12-21 | 2004-12-21 | |
| PCT/US2005/045563 WO2006068933A2 (en) | 2004-12-21 | 2005-12-15 | Mitotic kinesin inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008524329A JP2008524329A (ja) | 2008-07-10 |
| JP2008524329A5 true JP2008524329A5 (enExample) | 2008-12-11 |
Family
ID=36602225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007548319A Withdrawn JP2008524329A (ja) | 2004-12-21 | 2005-12-15 | 有糸分裂キネシン阻害剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080045492A1 (enExample) |
| EP (1) | EP1831176A2 (enExample) |
| JP (1) | JP2008524329A (enExample) |
| CN (1) | CN101084194A (enExample) |
| AU (1) | AU2005319455A1 (enExample) |
| CA (1) | CA2589827A1 (enExample) |
| WO (1) | WO2006068933A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007011647A2 (en) * | 2005-07-15 | 2007-01-25 | Kalypsys, Inc. | Inhibitors of mitotic kinesin ksp |
| EP2114891A1 (en) * | 2007-01-17 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | Substituted pyrazoline compounds with acat inhibition activity |
| EP1950202A1 (en) * | 2007-01-24 | 2008-07-30 | Laboratorios del Dr. Esteve S.A. | Substituted pyrazoline compounds, their preparation and use as medicaments with ACAT inhibition activity |
| KR20100072267A (ko) | 2007-10-19 | 2010-06-30 | 쉐링 코포레이션 | Ｋｓｐ 키네신 활성 억제용 스피로-축합된 1,3,4-티아디아졸 유도체 |
| CN101918389A (zh) * | 2007-11-02 | 2010-12-15 | 梅特希尔基因公司 | 组蛋白脱乙酰酶抑制剂 |
| US9029411B2 (en) | 2008-01-25 | 2015-05-12 | Millennium Pharmaceuticals, Inc. | Thiophenes and uses thereof |
| US9090601B2 (en) | 2009-01-30 | 2015-07-28 | Millennium Pharmaceuticals, Inc. | Thiazole derivatives |
| US8796314B2 (en) | 2009-01-30 | 2014-08-05 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| JP2012516329A (ja) | 2009-01-30 | 2012-07-19 | ミレニアム ファーマシューティカルズ， インコーポレイテッド | Ｐｉ３ｋ阻害剤としてのヘテロアリールおよびその使用 |
| WO2012021611A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2012021696A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| EP2603216A4 (en) | 2010-08-11 | 2013-12-18 | Millennium Pharm Inc | HETEROARYLE AND USES THEREOF |
| CA2814688A1 (en) | 2010-10-13 | 2012-04-19 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| CN103929964A (zh) | 2011-09-23 | 2014-07-16 | 拜耳知识产权有限责任公司 | 4-取代的1-苯基吡唑-3-甲酸衍生物作为对抗非生物植物胁迫的活性物质的用途 |
| JP2015503505A (ja) * | 2011-12-23 | 2015-02-02 | ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | ヘテロアリールおよびその使用 |
| WO2014134391A1 (en) | 2013-02-28 | 2014-09-04 | Bristol-Myers Squibb Company | Phenylpyrazole derivatives as potent rock1 and rock2 inhibitors |
| TW201444798A (zh) | 2013-02-28 | 2014-12-01 | 必治妥美雅史谷比公司 | 作爲強效ｒｏｃｋ１及ｒｏｃｋ２抑制劑之苯基吡唑衍生物 |
| CN103992274A (zh) * | 2014-04-18 | 2014-08-20 | 南京安美科技有限公司 | 合成选择性非甾体抗炎镇痛药Celebrex(塞来昔布)的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE423110T1 (de) * | 2002-07-17 | 2009-03-15 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen |
| US7618971B2 (en) * | 2004-07-01 | 2009-11-17 | Merck & Co. Inc. | Mitotic kinesin inhibitors |
| AU2006235022B2 (en) * | 2005-04-07 | 2011-07-21 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
-
2005
- 2005-12-15 AU AU2005319455A patent/AU2005319455A1/en not_active Abandoned
- 2005-12-15 US US11/793,090 patent/US20080045492A1/en not_active Abandoned
- 2005-12-15 WO PCT/US2005/045563 patent/WO2006068933A2/en not_active Ceased
- 2005-12-15 EP EP05854311A patent/EP1831176A2/en not_active Withdrawn
- 2005-12-15 CN CNA200580043954XA patent/CN101084194A/zh active Pending
- 2005-12-15 JP JP2007548319A patent/JP2008524329A/ja not_active Withdrawn
- 2005-12-15 CA CA002589827A patent/CA2589827A1/en not_active Abandoned
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