JP2008521796A5 - - Google Patents

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Publication number
JP2008521796A5
JP2008521796A5 JP2007542516A JP2007542516A JP2008521796A5 JP 2008521796 A5 JP2008521796 A5 JP 2008521796A5 JP 2007542516 A JP2007542516 A JP 2007542516A JP 2007542516 A JP2007542516 A JP 2007542516A JP 2008521796 A5 JP2008521796 A5 JP 2008521796A5
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JP
Japan
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use according
disease
stem cells
pharmaceutical composition
neuropathy
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JP2007542516A
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English (en)
Japanese (ja)
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JP2008521796A (ja
JP5294635B2 (ja
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Priority claimed from PCT/IL2005/001275 external-priority patent/WO2006057003A2/en
Publication of JP2008521796A publication Critical patent/JP2008521796A/ja
Publication of JP2008521796A5 publication Critical patent/JP2008521796A5/ja
Application granted granted Critical
Publication of JP5294635B2 publication Critical patent/JP5294635B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007542516A 2004-11-29 2005-11-29 コポリマー1と組み合わせた、神経発生の誘発及び幹細胞治療 Expired - Fee Related JP5294635B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US63116304P 2004-11-29 2004-11-29
US60/631,163 2004-11-29
US69049805P 2005-06-15 2005-06-15
US60/690,498 2005-06-15
PCT/IL2005/001275 WO2006057003A2 (en) 2004-11-29 2005-11-29 Induction of neurogenesis and stem cell therapy in combination with copolymer 1

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012248619A Division JP2013040204A (ja) 2004-11-29 2012-11-12 コポリマー1と組み合わせた、神経発生の誘発及び幹細胞治療

Publications (3)

Publication Number Publication Date
JP2008521796A JP2008521796A (ja) 2008-06-26
JP2008521796A5 true JP2008521796A5 (enExample) 2009-01-22
JP5294635B2 JP5294635B2 (ja) 2013-09-18

Family

ID=36498362

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007542516A Expired - Fee Related JP5294635B2 (ja) 2004-11-29 2005-11-29 コポリマー1と組み合わせた、神経発生の誘発及び幹細胞治療
JP2012248619A Abandoned JP2013040204A (ja) 2004-11-29 2012-11-12 コポリマー1と組み合わせた、神経発生の誘発及び幹細胞治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012248619A Abandoned JP2013040204A (ja) 2004-11-29 2012-11-12 コポリマー1と組み合わせた、神経発生の誘発及び幹細胞治療

Country Status (7)

Country Link
US (2) US20090191173A1 (enExample)
EP (1) EP1827108B1 (enExample)
JP (2) JP5294635B2 (enExample)
AU (1) AU2005308396B2 (enExample)
CA (1) CA2588908C (enExample)
ES (1) ES2541780T3 (enExample)
WO (1) WO2006057003A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
WO2009040814A1 (en) * 2007-09-24 2009-04-02 Hadasit Medical Research Services & Development Ltd Use of copolymer 1 for treatment of muscular dystrophy
WO2010071862A1 (en) * 2008-12-19 2010-06-24 Ethicon, Incorporated Umbilical cord tissue derived cells for treating neuropathic pain and spasticity
PL2411504T3 (pl) 2009-03-26 2017-10-31 Depuy Synthes Products Inc Komórki ludzkiej tkanki pępowinowej jako terapia choroby Alzheimera
AU2010289419A1 (en) * 2009-09-02 2012-03-29 The University Of Chicago Methods and systems for inducible ablation of neural cells
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
ES2601892T3 (es) 2011-04-21 2017-02-16 Mapi Pharma Limited Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
GB201300684D0 (en) 2013-01-15 2013-02-27 Apitope Int Nv Peptide
EP3478300B1 (en) 2016-06-30 2022-08-24 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
CN107703292B (zh) * 2016-08-09 2019-07-12 杨琴 BrdU标记免疫荧光检测细胞增殖的改良方法
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en) 2016-08-31 2024-09-05 Mapi Pharma Ltd Depot systems comprising glatiramer acetate
IL316573A (en) 2017-03-26 2024-12-01 Mapi Pharma Ltd Storage systems containing glatiramer acetate for the treatment of multiple sclerosis
IL269893B2 (en) 2017-05-15 2023-10-01 Stem Cell Medicine Ltd Treatment of multiple sclerosis with adipose-derived stem cells
EP3624815A4 (en) * 2017-05-15 2021-01-20 Stem Cell Medicine Ltd. TREATMENT OF MULTIPLE SCLEROSIS WITH LONG-ACTING GLATIRAMER AND ADAPTIVE STEM CELLS
EP3765034A1 (en) 2018-03-12 2021-01-20 Yeda Research and Development Co. Ltd Treatment of a heart disease
KR101994640B1 (ko) * 2018-03-16 2019-07-02 (주)메디노 신경줄기세포의 고효율 분리배양 방법
WO2020245832A1 (en) * 2019-06-07 2020-12-10 Ramot At Tel-Aviv University Ltd. Compositions and methods of using same for tissue regeneration

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980885A (en) * 1991-07-08 1999-11-09 Neurospheres Holdings Ltd. Growth factor-induced proliferation of neural precursor cells in vivo
US6497872B1 (en) * 1991-07-08 2002-12-24 Neurospheres Holdings Ltd. Neural transplantation using proliferated multipotent neural stem cells and their progeny
US6294346B1 (en) * 1991-07-08 2001-09-25 Neurospheres Holdings, Ltd. Use of multipotent neural stem cells and their progeny for the screening of drugs and other biological agents
US6071889A (en) * 1991-07-08 2000-06-06 Neurospheres Holdings Ltd. In vivo genetic modification of growth factor-responsive neural precursor cells
IL113812A (en) * 1994-05-24 2000-06-29 Yeda Res & Dev Copolymer-1 pharmaceutical compositions containing it and its use
IL112834A (en) * 1995-03-01 2000-12-06 Yeda Res & Dev Pharmaceutical compositions for controlled release of soluble receptors
US6214791B1 (en) * 1997-01-10 2001-04-10 Yeda Research And Development Co. Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
JP2002503658A (ja) * 1998-02-13 2002-02-05 オートイミューン インク COP−1及びTh−2促進性サイトカインを使用した、多発性硬化症の治療
SE9802264D0 (sv) * 1998-06-25 1998-06-25 Neuronova Ab A method of isolating cells
ES2527760T3 (es) * 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en) * 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US6531130B1 (en) * 1999-07-06 2003-03-11 The Board Of Trustees Of The Leland Stanford University Treatment of demyelinating autoimmune disease with ordered peptides
HK1054507B (zh) * 2000-01-20 2008-10-31 耶达研究及发展有限公司 共聚物1和相关肽和多肽及其处理过的t细胞在神经保护性治疗中的用途
US7037493B2 (en) * 2000-05-01 2006-05-02 Cornell Research Foundation, Inc. Method of inducing neuronal production in the brain and spinal cord
US20020077278A1 (en) * 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
DE60116467T2 (de) * 2000-06-07 2006-11-02 Yeda Research And Development Co., Ltd. Verwendung des Copolymer-1 Peptids sowie von damit verwandten Peptiden und Polypeptiden und von damit behandelten T-Zellen zur Neuroprotektion gegen die Toxizität von Glutamat
US6835711B2 (en) * 2001-06-28 2004-12-28 Yeda Research And Development Co. Ltd. Use of poly-Glu,Tyr for neuroprotective therapy
US7399740B2 (en) * 2001-06-28 2008-07-15 Yeda Research And Development Co. Ltd. Poly-Glu,Tyr for neuroprotective therapy
EP1459065B1 (en) * 2001-12-04 2010-07-28 Teva Pharmaceutical Industries, Ltd. Processes for the measurement of the potency of glatiramer acetate
JP4374469B2 (ja) * 2002-01-09 2009-12-02 独立行政法人科学技術振興機構 記憶障害治療剤
US7576065B2 (en) * 2002-02-15 2009-08-18 Cornell Research Foundation, Inc. Enhancing neurotrophin-induced neurogenesis by endogenous neural progenitor cells by concurrent overexpression of brain derived neurotrophic factor and an inhibitor of a pro-gliogenic bone morphogenetic protein
WO2005032482A2 (en) * 2003-10-03 2005-04-14 Bayhill Therapeutics, Inc. Treatment of demyelinating autoimmune disease with modified ordered peptides

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