JP2008520544A5 - 癌関連疲労の治療または予防のための医薬の製造への使用方法 - Google Patents
癌関連疲労の治療または予防のための医薬の製造への使用方法 Download PDFInfo
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- JP2008520544A5 JP2008520544A5 JP2007532464A JP2007532464A JP2008520544A5 JP 2008520544 A5 JP2008520544 A5 JP 2008520544A5 JP 2007532464 A JP2007532464 A JP 2007532464A JP 2007532464 A JP2007532464 A JP 2007532464A JP 2008520544 A5 JP2008520544 A5 JP 2008520544A5
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- trh
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- medicament
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- 239000003814 drug Substances 0.000 title claims 9
- 238000004519 manufacturing process Methods 0.000 title claims 7
- 230000002265 prevention Effects 0.000 title claims 3
- 201000011510 cancer Diseases 0.000 title claims 2
- 239000000816 peptidomimetic Substances 0.000 claims 4
- 239000002552 dosage form Substances 0.000 claims 2
- 229940079593 drugs Drugs 0.000 claims 2
- 102000011923 Thyrotropin Human genes 0.000 claims 1
- 108010061174 Thyrotropin Proteins 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 230000001747 exhibiting Effects 0.000 claims 1
- 150000004677 hydrates Chemical class 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 230000001613 neoplastic Effects 0.000 claims 1
- 230000002085 persistent Effects 0.000 claims 1
- 230000000770 pro-inflamatory Effects 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 229940002612 prodrugs Drugs 0.000 claims 1
- 239000003488 releasing hormone Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
Claims (9)
- 甲状腺刺激ホルモン放出ホルモン（ＴＲＨ）、ＴＲＨ類似体、ＴＲＨおよびＴＲＨ類似体の医薬的に許容し得る塩、水和物およびプロドラッグから選択される薬物の、腫瘍性疾患を患うヒト患者における癌関連疲労の治療または予防のための医薬の製造への使用方法。
- 休息によって軽減されない、重篤で持続的な疲労の治療または予防のための医薬の製造への請求項１に記載の使用方法。
- 薬物がＴＲＨまたはＴＲＨのペプチド模倣類似体である請求項１または請求項２に記載の使用方法。
- 手術、放射線治療、化学療法剤による治療および免疫療法剤による治療の少なくとも１つを受けた患者の治療に適した医薬の製造への請求項１から請求項３のいずれか一項に記載の使用方法。
- ＨＰＡ軸機能不全および／または前炎症活性を示す対象に用いるのに適した医薬の製造への請求項１から請求項４のいずれか一項に記載の使用方法。
- ＴＲＨのペプチド模倣類似体が下式で表される請求項３に記載の使用方法。
- 経口的な、経皮的な、吸入による、注射による、経鼻的な、または経直腸的な投与のための医薬の製造への請求項１から請求項６のいずれか一項に記載の使用方法。
- １日あたり約０．０１ｍｇ／ｋｇから約２ｍｇ／ｋｇまでのＴＲＨのペプチド模倣類似体を与えるように、１日１回から３回経口投与するための投薬形態の医薬の製造への請求項７に記載の使用方法。
- 約５ｍｇから約３０ｍｇまでのＴＲＨのペプチド模倣類似体を含む投薬形態の医薬の製造への請求項１から請求項８のいずれか一項に記載の使用方法。
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61073704P | 2004-09-17 | 2004-09-17 | |
| US62948304P | 2004-11-19 | 2004-11-19 | |
| US11/225,997 US7462595B2 (en) | 2004-09-17 | 2005-09-14 | Methods for treating cancer-related fatigue |
| PCT/US2005/032973 WO2006031980A2 (en) | 2004-09-17 | 2005-09-15 | Treatment for cancer-related fatigue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008520544A JP2008520544A (ja) | 2008-06-19 |
| JP2008520544A5 true JP2008520544A5 (ja) | 2008-10-30 |
Family
ID=36060706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007532464A Pending JP2008520544A (ja) | 2004-09-17 | 2005-09-15 | 癌関連疲労のための処置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7462595B2 (ja) |
| EP (1) | EP1793842B1 (ja) |
| JP (1) | JP2008520544A (ja) |
| ES (1) | ES2452020T3 (ja) |
| PL (1) | PL1793842T3 (ja) |
| WO (1) | WO2006031980A2 (ja) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2698690A1 (en) * | 2007-09-11 | 2009-04-09 | Mondobiotech Laboratories Ag | Thyrotropin releasing hormone for therapeutic applications |
| JP2010538989A (ja) * | 2007-09-11 | 2010-12-16 | モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト | Ｈｂｖ感染等の治療における治療剤としてのｎｆ−カッパーｂインヒビターｓｎ５０の使用、及び必要に応じたアンギオテンシンｉｉｉの使用 |
| US8597883B2 (en) | 2011-02-14 | 2013-12-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Biomarkers for cancer-related fatigue and use thereof |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US9314417B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Treatment of skin, including aging skin, to improve appearance |
| US9849160B2 (en) | 2013-03-13 | 2017-12-26 | Transdermal Biotechnology, Inc. | Methods and systems for treating or preventing cancer |
| US20140271937A1 (en) | 2013-03-13 | 2014-09-18 | Transdermal Biotechnology, Inc. | Brain and neural treatments comprising peptides and other compositions |
| US9724419B2 (en) | 2013-03-13 | 2017-08-08 | Transdermal Biotechnology, Inc. | Peptide systems and methods for metabolic conditions |
| US9393265B2 (en) | 2013-03-13 | 2016-07-19 | Transdermal Biotechnology, Inc. | Wound healing using topical systems and methods |
| US9387159B2 (en) | 2013-03-13 | 2016-07-12 | Transdermal Biotechnology, Inc. | Treatment of skin, including aging skin, to improve appearance |
| US9393264B2 (en) | 2013-03-13 | 2016-07-19 | Transdermal Biotechnology, Inc. | Immune modulation using peptides and other compositions |
| US9320706B2 (en) | 2013-03-13 | 2016-04-26 | Transdermal Biotechnology, Inc. | Immune modulation using peptides and other compositions |
| US20140271731A1 (en) | 2013-03-13 | 2014-09-18 | Transdermal Biotechnology, Inc. | Cardiovascular disease treatment and prevention |
| US9320758B2 (en) | 2013-03-13 | 2016-04-26 | Transdermal Biotechnology, Inc. | Brain and neural treatments comprising peptides and other compositions |
| US9339457B2 (en) | 2013-03-13 | 2016-05-17 | Transdermal Biotechnology, Inc. | Cardiovascular disease treatment and prevention |
| US9295636B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Wound healing using topical systems and methods |
| US20140271938A1 (en) | 2013-03-13 | 2014-09-18 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of peptides |
| US9750787B2 (en) | 2013-03-13 | 2017-09-05 | Transdermal Biotechnology, Inc. | Memory or learning improvement using peptide and other compositions |
| US9295647B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of peptides |
| US9314423B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Hair treatment systems and methods using peptides and other compositions |
| US9295637B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Compositions and methods for affecting mood states |
| US9687520B2 (en) | 2013-03-13 | 2017-06-27 | Transdermal Biotechnology, Inc. | Memory or learning improvement using peptide and other compositions |
| US9241899B2 (en) | 2013-03-13 | 2016-01-26 | Transdermal Biotechnology, Inc. | Topical systems and methods for treating sexual dysfunction |
| US9314433B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Methods and systems for treating or preventing cancer |
| US9314422B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Peptide systems and methods for metabolic conditions |
| JP6742904B2 (ja) * | 2013-11-08 | 2020-08-19 | レガシー ヘルスケア リミテッド | ガンおよびガン共存症の治療に使用するための組成物 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959248A (en) * | 1974-04-03 | 1976-05-25 | Merck & Co., Inc. | Analogs of thyrotropin-releasing hormone |
| JPS51118841A (en) * | 1975-04-03 | 1976-10-19 | Takeda Chem Ind Ltd | A drug for improving and treating clouding of consciousness |
| HU180925B (en) * | 1979-06-28 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing tripeptide-amides trh-analogues,effectives on the central nerve systhem |
| US4426378A (en) * | 1981-04-09 | 1984-01-17 | The United States Of America As Represented By The Secretary Of The Army | Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant |
| CA1256650A (en) * | 1983-03-25 | 1989-06-27 | Toshinari Tamura | Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds |
| GB2146026A (en) * | 1983-09-07 | 1985-04-11 | Tanabe Seiyaku Co | Peptides and process for preparing the same |
| US4719207A (en) * | 1984-06-25 | 1988-01-12 | Yamanouchi Pharmaceutical Co., Ltd. | CNS active substituted azetidinone compounds |
| IE58849B1 (en) * | 1984-12-18 | 1993-11-17 | Gruenenthal Chemie | Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis |
| DE3502041A1 (de) * | 1985-01-23 | 1986-07-24 | Grünenthal GmbH, 5190 Stolberg | Verwendung von dipeptidderivaten zur behandlung posttraumatischer nervenschaeden |
| GB2171101A (en) * | 1985-02-20 | 1986-08-20 | Tanabe Seiyaku Co | Peptide and processes for preparation of the same |
| GB2219501B (en) * | 1987-04-08 | 1990-09-26 | Nippon Shinyaku Co Ltd | Nootropic agent. |
| US5686420A (en) * | 1987-06-05 | 1997-11-11 | Georgetown University | Thyrotropin-releasing hormone analogs and method of use |
| JPS63316724A (ja) * | 1987-06-19 | 1988-12-26 | Nippon Shinyaku Co Ltd | 抗けいれん剤 |
| US5151497A (en) * | 1989-02-21 | 1992-09-29 | Japan Tobacco Inc. | Histidyl peptide derivatives |
| DK437289D0 (da) * | 1989-09-04 | 1989-09-04 | Hans Bundgaard | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
| US5244884A (en) * | 1990-07-06 | 1993-09-14 | The United States Of America As Represented By The Department Of Health And Human Services | Thionated analogues of thyrotropin releasing hormone |
| US5811512A (en) * | 1991-08-22 | 1998-09-22 | The Trustees Of The University Of Pennsylvania | Non-peptide peptidomimetics and related cyclic hexapeptides |
| US5526378A (en) * | 1994-12-14 | 1996-06-11 | Thomson Consumer Electronics, Inc. | Blind multipath correction for digital communication channel |
| US5968932A (en) * | 1995-10-24 | 1999-10-19 | Gruenenthal Gmbh | Method of inhibiting sleep apnea |
| US6475989B1 (en) * | 1997-10-09 | 2002-11-05 | Albert Sattin | Use of pyroglutamyl-glutamyl-prolyl amide (EEP) for neurological and neurobehavioral disorders |
| AU4911500A (en) * | 1999-06-04 | 2000-12-28 | Novo Nordisk A/S | Compositions for the treatment of the catabolic state of prolonged critical illness |
| US6815425B1 (en) * | 1999-10-22 | 2004-11-09 | The United States Of America As Represented By The Secretary Of The Army | Pharmaceutical composition containing pGLU-GLU-PRO-NH2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
| IE20000240A1 (en) | 2000-02-17 | 2003-03-05 | Trinity College Dublin | TRH-like peptide derivatives |
| AU2003228610A1 (en) * | 2002-04-19 | 2003-11-03 | University Of Florida | Thyrotropin-releasing hormone analogues and their therapeutic applications |
-
2005
- 2005-09-14 US US11/225,997 patent/US7462595B2/en not_active Expired - Fee Related
- 2005-09-15 ES ES05812341.5T patent/ES2452020T3/es active Active
- 2005-09-15 PL PL05812341T patent/PL1793842T3/pl unknown
- 2005-09-15 JP JP2007532464A patent/JP2008520544A/ja active Pending
- 2005-09-15 WO PCT/US2005/032973 patent/WO2006031980A2/en active Application Filing
- 2005-09-15 EP EP05812341.5A patent/EP1793842B1/en not_active Not-in-force
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