JP2008520241A5 - - Google Patents

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Publication number
JP2008520241A5
JP2008520241A5 JP2007543209A JP2007543209A JP2008520241A5 JP 2008520241 A5 JP2008520241 A5 JP 2008520241A5 JP 2007543209 A JP2007543209 A JP 2007543209A JP 2007543209 A JP2007543209 A JP 2007543209A JP 2008520241 A5 JP2008520241 A5 JP 2008520241A5
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JP
Japan
Prior art keywords
antibody
medicament according
antibody fragment
domain
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007543209A
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English (en)
Japanese (ja)
Other versions
JP5341350B2 (ja
JP2008520241A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/041594 external-priority patent/WO2006055665A2/en
Publication of JP2008520241A publication Critical patent/JP2008520241A/ja
Publication of JP2008520241A5 publication Critical patent/JP2008520241A5/ja
Application granted granted Critical
Publication of JP5341350B2 publication Critical patent/JP5341350B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2007543209A 2004-11-16 2005-11-15 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割 Expired - Lifetime JP5341350B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62844704P 2004-11-16 2004-11-16
US60/628,447 2004-11-16
US69426805P 2005-06-27 2005-06-27
US60/694,268 2005-06-27
PCT/US2005/041594 WO2006055665A2 (en) 2004-11-16 2005-11-15 Roles for dual endothelin-1/angiotensin ii receptor (dear) in hypertension and angiogenesis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012168420A Division JP2012233000A (ja) 2004-11-16 2012-07-30 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割

Publications (3)

Publication Number Publication Date
JP2008520241A JP2008520241A (ja) 2008-06-19
JP2008520241A5 true JP2008520241A5 (enExample) 2011-03-17
JP5341350B2 JP5341350B2 (ja) 2013-11-13

Family

ID=36407731

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007543209A Expired - Lifetime JP5341350B2 (ja) 2004-11-16 2005-11-15 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割
JP2012168420A Pending JP2012233000A (ja) 2004-11-16 2012-07-30 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012168420A Pending JP2012233000A (ja) 2004-11-16 2012-07-30 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割

Country Status (6)

Country Link
US (3) US7919093B2 (enExample)
EP (2) EP1812473A4 (enExample)
JP (2) JP5341350B2 (enExample)
AU (1) AU2005307765C1 (enExample)
CA (1) CA2588066A1 (enExample)
WO (1) WO2006055665A2 (enExample)

Families Citing this family (16)

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AU2002231736A1 (en) 2000-12-22 2002-07-08 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Use of repulsive guidance molecule (rgm) and its modulators
CN101277974A (zh) * 2005-09-30 2008-10-01 阿伯特有限及两合公司 排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
AU2007233320B2 (en) 2006-04-04 2013-12-12 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
EP2033971A1 (de) * 2007-09-06 2009-03-11 Abbott GmbH & Co. KG Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung
US8962803B2 (en) * 2008-02-29 2015-02-24 AbbVie Deutschland GmbH & Co. KG Antibodies against the RGM A protein and uses thereof
WO2010144358A1 (en) 2009-06-08 2010-12-16 Singulex, Inc. Highly sensitive biomarker panels
PH12012501070A1 (en) * 2009-12-08 2017-08-23 Abbott Gmbh & Co Kg Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
SG187592A1 (en) 2010-07-23 2013-03-28 Univ Boston Anti-despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
US20130022551A1 (en) * 2011-07-22 2013-01-24 Trustees Of Boston University DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS
AU2013211939C1 (en) 2012-01-27 2018-06-07 AbbVie Deutschland GmbH & Co. KG Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
EP3341413A4 (en) 2015-08-24 2019-07-17 Trustees of Boston University THERAPY AND IMAGING FOR CANCER AND STROKE ON MONOCLONAL ANTI-DESPR ANTIBODIES
JP7404230B2 (ja) 2017-09-18 2023-12-25 トラスティーズ オブ ボストン ユニバーシティ ネトーシスおよび好中球活性化を処置するための方法
WO2019241609A1 (en) 2018-06-15 2019-12-19 Trustees Of Boston University Polypeptide compositions and methods for site-specific targeting of therapeutic agents
WO2022081792A1 (en) 2020-10-15 2022-04-21 Trustees Of Boston University Antibody therapies and methods for treating coronavirus infection
CN116530469B (zh) * 2023-07-06 2023-09-19 首都医科大学 腹主动脉瘤动物模型的制备方法与应用

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US3625214A (en) 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4411993A (en) 1981-04-29 1983-10-25 Steven Gillis Hybridoma antibody which inhibits interleukin 2 activity
US4543439A (en) 1982-12-13 1985-09-24 Massachusetts Institute Of Technology Production and use of monoclonal antibodies to phosphotyrosine-containing proteins
US4906474A (en) 1983-03-22 1990-03-06 Massachusetts Institute Of Technology Bioerodible polyanhydrides for controlled drug delivery
US4902614A (en) 1984-12-03 1990-02-20 Teijin Limited Monoclonal antibody to human protein C
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4789734A (en) 1985-08-06 1988-12-06 La Jolla Cancer Research Foundation Vitronectin specific cell receptor derived from mammalian mesenchymal tissue
NO870613L (no) 1986-03-05 1987-09-07 Molecular Diagnostics Inc Deteksjon av mikroorganismer i en prŸve inneholdende nukleinsyre.
US4925673A (en) 1986-08-18 1990-05-15 Clinical Technologies Associates, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
JP2897959B2 (ja) 1988-05-20 1999-05-31 エフ.ホフマン―ラ ロシュ アクチェンゲゼルシャフト 固定化された配列特異的プローブ
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5440021A (en) * 1991-03-29 1995-08-08 Chuntharapai; Anan Antibodies to human IL-8 type B receptor
CA2134552A1 (en) 1992-04-27 1993-11-11 George D. Sorenson Detection of gene sequences in biological fluids
US5593688A (en) 1993-06-25 1997-01-14 Nexstar Pharmaceuticals, Inc. Liposomal targeting of ischemic tissue
WO1995011995A1 (en) 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
WO1997040462A2 (en) 1996-04-19 1997-10-30 Spectra Biomedical, Inc. Correlating polymorphic forms with multiple phenotypes
EP0979869A1 (en) 1998-08-07 2000-02-16 Hoechst Marion Roussel Deutschland GmbH Short oligonucleotides for the inhibition of VEGF expression
US6641811B1 (en) * 2000-02-10 2003-11-04 Cornell Research Foundation, Inc. Use of angiotensin II inhibitors to prevent malignancies associated with immunosuppression

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