JP2008520241A5 - - Google Patents
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- JP2008520241A5 JP2008520241A5 JP2007543209A JP2007543209A JP2008520241A5 JP 2008520241 A5 JP2008520241 A5 JP 2008520241A5 JP 2007543209 A JP2007543209 A JP 2007543209A JP 2007543209 A JP2007543209 A JP 2007543209A JP 2008520241 A5 JP2008520241 A5 JP 2008520241A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- medicament according
- antibody fragment
- domain
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62844704P | 2004-11-16 | 2004-11-16 | |
| US60/628,447 | 2004-11-16 | ||
| US69426805P | 2005-06-27 | 2005-06-27 | |
| US60/694,268 | 2005-06-27 | ||
| PCT/US2005/041594 WO2006055665A2 (en) | 2004-11-16 | 2005-11-15 | Roles for dual endothelin-1/angiotensin ii receptor (dear) in hypertension and angiogenesis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012168420A Division JP2012233000A (ja) | 2004-11-16 | 2012-07-30 | 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008520241A JP2008520241A (ja) | 2008-06-19 |
| JP2008520241A5 true JP2008520241A5 (enExample) | 2011-03-17 |
| JP5341350B2 JP5341350B2 (ja) | 2013-11-13 |
Family
ID=36407731
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007543209A Expired - Lifetime JP5341350B2 (ja) | 2004-11-16 | 2005-11-15 | 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割 |
| JP2012168420A Pending JP2012233000A (ja) | 2004-11-16 | 2012-07-30 | 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012168420A Pending JP2012233000A (ja) | 2004-11-16 | 2012-07-30 | 高血圧および血管新生におけるエンドセリン−1/アンジオテンシンii二重レセプター(dear)の役割 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7919093B2 (enExample) |
| EP (2) | EP1812473A4 (enExample) |
| JP (2) | JP5341350B2 (enExample) |
| AU (1) | AU2005307765C1 (enExample) |
| CA (1) | CA2588066A1 (enExample) |
| WO (1) | WO2006055665A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002231736A1 (en) | 2000-12-22 | 2002-07-08 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Use of repulsive guidance molecule (rgm) and its modulators |
| CN101277974A (zh) * | 2005-09-30 | 2008-10-01 | 阿伯特有限及两合公司 | 排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途 |
| US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| AU2007233320B2 (en) | 2006-04-04 | 2013-12-12 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| EP2033971A1 (de) * | 2007-09-06 | 2009-03-11 | Abbott GmbH & Co. KG | Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung |
| US8962803B2 (en) * | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
| WO2010144358A1 (en) | 2009-06-08 | 2010-12-16 | Singulex, Inc. | Highly sensitive biomarker panels |
| PH12012501070A1 (en) * | 2009-12-08 | 2017-08-23 | Abbott Gmbh & Co Kg | Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration |
| SG187592A1 (en) | 2010-07-23 | 2013-03-28 | Univ Boston | Anti-despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery |
| US20130022551A1 (en) * | 2011-07-22 | 2013-01-24 | Trustees Of Boston University | DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS |
| AU2013211939C1 (en) | 2012-01-27 | 2018-06-07 | AbbVie Deutschland GmbH & Co. KG | Composition and method for diagnosis and treatment of diseases associated with neurite degeneration |
| EP3341413A4 (en) | 2015-08-24 | 2019-07-17 | Trustees of Boston University | THERAPY AND IMAGING FOR CANCER AND STROKE ON MONOCLONAL ANTI-DESPR ANTIBODIES |
| JP7404230B2 (ja) | 2017-09-18 | 2023-12-25 | トラスティーズ オブ ボストン ユニバーシティ | ネトーシスおよび好中球活性化を処置するための方法 |
| WO2019241609A1 (en) | 2018-06-15 | 2019-12-19 | Trustees Of Boston University | Polypeptide compositions and methods for site-specific targeting of therapeutic agents |
| WO2022081792A1 (en) | 2020-10-15 | 2022-04-21 | Trustees Of Boston University | Antibody therapies and methods for treating coronavirus infection |
| CN116530469B (zh) * | 2023-07-06 | 2023-09-19 | 首都医科大学 | 腹主动脉瘤动物模型的制备方法与应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3625214A (en) | 1970-05-18 | 1971-12-07 | Alza Corp | Drug-delivery device |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4906474A (en) | 1983-03-22 | 1990-03-06 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4789734A (en) | 1985-08-06 | 1988-12-06 | La Jolla Cancer Research Foundation | Vitronectin specific cell receptor derived from mammalian mesenchymal tissue |
| NO870613L (no) | 1986-03-05 | 1987-09-07 | Molecular Diagnostics Inc | Deteksjon av mikroorganismer i en prve inneholdende nukleinsyre. |
| US4925673A (en) | 1986-08-18 | 1990-05-15 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents encapsulated with proteinoids |
| JP2897959B2 (ja) | 1988-05-20 | 1999-05-31 | エフ.ホフマン―ラ ロシュ アクチェンゲゼルシャフト | 固定化された配列特異的プローブ |
| US5410016A (en) | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
| US5440021A (en) * | 1991-03-29 | 1995-08-08 | Chuntharapai; Anan | Antibodies to human IL-8 type B receptor |
| CA2134552A1 (en) | 1992-04-27 | 1993-11-11 | George D. Sorenson | Detection of gene sequences in biological fluids |
| US5593688A (en) | 1993-06-25 | 1997-01-14 | Nexstar Pharmaceuticals, Inc. | Liposomal targeting of ischemic tissue |
| WO1995011995A1 (en) | 1993-10-26 | 1995-05-04 | Affymax Technologies N.V. | Arrays of nucleic acid probes on biological chips |
| WO1997040462A2 (en) | 1996-04-19 | 1997-10-30 | Spectra Biomedical, Inc. | Correlating polymorphic forms with multiple phenotypes |
| EP0979869A1 (en) | 1998-08-07 | 2000-02-16 | Hoechst Marion Roussel Deutschland GmbH | Short oligonucleotides for the inhibition of VEGF expression |
| US6641811B1 (en) * | 2000-02-10 | 2003-11-04 | Cornell Research Foundation, Inc. | Use of angiotensin II inhibitors to prevent malignancies associated with immunosuppression |
-
2005
- 2005-11-15 US US11/667,713 patent/US7919093B2/en active Active
- 2005-11-15 WO PCT/US2005/041594 patent/WO2006055665A2/en not_active Ceased
- 2005-11-15 CA CA 2588066 patent/CA2588066A1/en not_active Abandoned
- 2005-11-15 EP EP05851729A patent/EP1812473A4/en not_active Withdrawn
- 2005-11-15 EP EP20100153754 patent/EP2194144B1/en not_active Expired - Lifetime
- 2005-11-15 JP JP2007543209A patent/JP5341350B2/ja not_active Expired - Lifetime
- 2005-11-15 AU AU2005307765A patent/AU2005307765C1/en not_active Expired
-
2011
- 2011-02-18 US US13/030,557 patent/US20110142821A1/en not_active Abandoned
-
2012
- 2012-07-30 JP JP2012168420A patent/JP2012233000A/ja active Pending
-
2014
- 2014-01-27 US US14/164,641 patent/US8956609B2/en not_active Expired - Lifetime
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