JP2008520187A5 - - Google Patents

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Publication number
JP2008520187A5
JP2008520187A5 JP2007537962A JP2007537962A JP2008520187A5 JP 2008520187 A5 JP2008520187 A5 JP 2008520187A5 JP 2007537962 A JP2007537962 A JP 2007537962A JP 2007537962 A JP2007537962 A JP 2007537962A JP 2008520187 A5 JP2008520187 A5 JP 2008520187A5
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JP
Japan
Prior art keywords
flavivirus
chimeric
mutation
chimeric flavivirus
virus
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JP2007537962A
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English (en)
Japanese (ja)
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JP4993301B2 (ja
JP2008520187A (ja
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Priority claimed from PCT/US2005/037369 external-priority patent/WO2006044857A2/en
Publication of JP2008520187A publication Critical patent/JP2008520187A/ja
Publication of JP2008520187A5 publication Critical patent/JP2008520187A5/ja
Application granted granted Critical
Publication of JP4993301B2 publication Critical patent/JP4993301B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007537962A 2004-10-20 2005-10-19 日本脳炎ウイルスおよび西ナイルウイルスに対するワクチン Expired - Lifetime JP4993301B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US62046604P 2004-10-20 2004-10-20
US60/620,466 2004-10-20
US62094804P 2004-10-21 2004-10-21
US60/620,948 2004-10-21
US67441505P 2005-04-24 2005-04-24
US60/674,415 2005-04-24
US67454605P 2005-04-25 2005-04-25
US60/674,546 2005-04-25
US71892305P 2005-09-19 2005-09-19
US60/718,923 2005-09-19
PCT/US2005/037369 WO2006044857A2 (en) 2004-10-20 2005-10-19 Vaccines against japanese encephalitis virus and west nile virus

Publications (3)

Publication Number Publication Date
JP2008520187A JP2008520187A (ja) 2008-06-19
JP2008520187A5 true JP2008520187A5 (https=) 2011-02-03
JP4993301B2 JP4993301B2 (ja) 2012-08-08

Family

ID=36203650

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007537962A Expired - Lifetime JP4993301B2 (ja) 2004-10-20 2005-10-19 日本脳炎ウイルスおよび西ナイルウイルスに対するワクチン

Country Status (13)

Country Link
US (2) US8029802B2 (https=)
EP (1) EP1809325B1 (https=)
JP (1) JP4993301B2 (https=)
KR (1) KR101501162B1 (https=)
AU (1) AU2005295438B2 (https=)
CA (1) CA2584228C (https=)
EA (1) EA015907B1 (https=)
IL (1) IL182453A0 (https=)
MY (1) MY148075A (https=)
NO (1) NO20071924L (https=)
NZ (1) NZ584079A (https=)
SG (1) SG156666A1 (https=)
WO (1) WO2006044857A2 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102828A2 (en) 2001-06-01 2002-12-27 Acambis, Inc. Chimeric flavivirus vectors
KR101194818B1 (ko) 2002-01-15 2012-10-25 사노피 파스테르 바이오로직스, 엘엘씨 플라비바이러스 백신
ATE452900T1 (de) 2002-11-15 2010-01-15 Sanofi Pasteur Biologics Co Impfstoff gegen das west-nile-virus
JP4993301B2 (ja) 2004-10-20 2012-08-08 サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー 日本脳炎ウイルスおよび西ナイルウイルスに対するワクチン
AU2013204985B2 (en) * 2005-04-24 2016-01-28 Sanofi Pasteur Biologics, Llc Recombinant flavivirus vaccines
CA2605924A1 (en) 2005-04-24 2006-11-02 Acambis Inc. Recombinant flavivirus vaccines
SG10202012986SA (en) 2006-09-29 2021-01-28 Ligocyte Pharmaceuticals Inc Norovirus vaccine formulations
CL2007003209A1 (es) 2006-11-07 2008-05-09 Acambis Inc Composicion que comprende una vacuna de flavivirus vivos atenuados; composicion que comprende un producto farmaceutico derivado de virus o proteina; un metodo para la elaboracion de una composicion terapeutica que comprende liofilizar las composicion
CA2676775A1 (en) * 2007-01-31 2008-09-25 Sanofi Pasteur Biologics Co. Flavivirus vaccine vector against influenza virus
US20100266636A1 (en) 2007-09-18 2010-10-21 Ligocyte Pharmaceuticals, Inc. Method of conferring a protective immune response to norovirus
JP2010539192A (ja) 2007-09-18 2010-12-16 リゴサイト ファーマスーティカルズ,インコーポレイテッド ノロウイルスに対して防御免疫応答を付与する方法
US8715689B2 (en) * 2008-04-30 2014-05-06 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Chimeric west nile/dengue viruses
AU2009279456B2 (en) 2008-08-08 2015-02-05 Takeda Vaccines, Inc. Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity
CN102292345B (zh) * 2008-11-17 2015-12-02 Vgx药品有限责任公司 引起对抗黄病毒的免疫应答的抗原及其应用方法
NZ597000A (en) * 2009-06-01 2014-07-25 Takeda Vaccines Inc Compositions and methods for administration of vaccines against dengue virus
US8968996B2 (en) 2009-06-01 2015-03-03 Takeda Vaccines, Inc. Compositions and methods for rapid immunization against dengue virus
CA3150430A1 (en) 2009-07-31 2011-02-03 Pnuvax Inc. High yield yellow fever virus strain with increased propagation in cells
EP2550292B1 (en) * 2010-03-24 2017-11-22 Research Development Foundation Flavivirus host range mutations and uses thereof
CN101926989A (zh) * 2010-06-29 2010-12-29 西北农林科技大学 表达jev免疫原基因的重组减毒鼠伤寒沙门氏菌载体疫苗及其制备方法
WO2012003320A2 (en) * 2010-07-01 2012-01-05 Research Development Foundation Flavivirus host-range mutations and uses thereof
CA2841356C (en) 2011-07-11 2022-03-01 Takeda Vaccines, Inc. Parenteral norovirus vaccine formulations
US9267114B2 (en) * 2012-11-07 2016-02-23 Southern Research Institute Flavivirus envelope protein mutations affecting virion disassembly
JP2016504315A (ja) 2012-12-14 2016-02-12 タケダ ワクチン, インコーポレイテッドTakeda Vaccines, Inc. 三価デングウイルス製剤に関する組成物、投与方法および使用
BR112015031226A2 (pt) 2013-06-21 2017-08-29 Merck Sharp & Dohme Composição de vacina, e, uso da composição de vacina
EP3013852B1 (en) 2013-06-26 2019-06-19 The University of North Carolina at Chapel Hill Compositions for dengue virus vaccines and their use
WO2016079560A1 (en) 2014-11-21 2016-05-26 Institut Pasteur A live and attenuated japanese encephalitis virus comprising a mutated m protein
EP3236997B1 (en) 2014-12-22 2024-05-29 Merck Sharp & Dohme LLC Dengue virus vaccine compositions and methods of use thereof
UA126548C2 (uk) * 2015-07-16 2022-11-02 Бхарат Біотек Інтернешнл Лімітед Вакцинна композиція для профілактики абровірусних інфекцій
BR112021019241A8 (pt) * 2019-03-28 2022-12-06 Pasteur Institut Flavivírus vivos e atenuados, ácidos nucleicos de rna e de cdna, células recombinantes, clones de cdna, composições imunogênicas e vírus do nilo ocidental (wnv) vivo e atenuado
EP4724462A1 (en) * 2023-06-08 2026-04-15 ModernaTX, Inc. Stabilized flavivirus vaccines

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173418A (en) 1985-05-10 1992-12-22 Benzon Pharma, A/S Production in Escherichia coli of extracellular Serratia spp. hydrolases
US6676936B1 (en) 1988-07-14 2004-01-13 The United States Of America As Represented By The Department Of Health And Human Services. Chimeric and/or growth-restricted flaviviruses
US6184024B1 (en) 1988-07-14 2001-02-06 The United States Of America As Represented By The Department Of Health And Human Services Chimeric and/or growth-restricted flaviviruses
US6962708B1 (en) 1997-02-28 2005-11-08 Acambis, Inc. Chimeric flavivirus vaccines
HU228705B1 (en) 1997-02-28 2013-05-28 Univ St Louis Chimeric flavivirus vaccines
US6589533B1 (en) 1997-09-18 2003-07-08 Research Development Foundation Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype
ATE314476T1 (de) 1997-10-08 2006-01-15 Us Gov Health & Human Serv Chimärer impfstoff gegen das zeckenenzephalitis virus
US7227011B2 (en) * 1998-06-04 2007-06-05 United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Nucleic acid vaccines for prevention of flavivirus infection
WO2001039802A1 (en) 1999-12-01 2001-06-07 Oravax, Inc. Chimeric flavivirus vaccines
WO2002081753A1 (en) 2001-04-04 2002-10-17 Advanced Research & Technology Institute Method for identifying and characterizing individual dna molecules
KR101194818B1 (ko) 2002-01-15 2012-10-25 사노피 파스테르 바이오로직스, 엘엘씨 플라비바이러스 백신
US20050002968A1 (en) 2002-01-15 2005-01-06 Monath Thomas P. Flavivirus vaccines
WO2003060088A2 (en) 2002-01-15 2003-07-24 Acambis, Inc. Viral vaccine production method
ATE452900T1 (de) 2002-11-15 2010-01-15 Sanofi Pasteur Biologics Co Impfstoff gegen das west-nile-virus
US7189403B2 (en) * 2003-06-30 2007-03-13 Institut Pasteur Attenuated flavivirus strains containing a mutated M-ectodomain and their applications
JP4993301B2 (ja) 2004-10-20 2012-08-08 サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー 日本脳炎ウイルスおよび西ナイルウイルスに対するワクチン
CA2605924A1 (en) 2005-04-24 2006-11-02 Acambis Inc. Recombinant flavivirus vaccines

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