JP2008519858A5 - - Google Patents

Download PDF

Info

Publication number
JP2008519858A5
JP2008519858A5 JP2007541390A JP2007541390A JP2008519858A5 JP 2008519858 A5 JP2008519858 A5 JP 2008519858A5 JP 2007541390 A JP2007541390 A JP 2007541390A JP 2007541390 A JP2007541390 A JP 2007541390A JP 2008519858 A5 JP2008519858 A5 JP 2008519858A5
Authority
JP
Japan
Prior art keywords
peptide
daltons
peg
molecular weight
dimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007541390A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008519858A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/041113 external-priority patent/WO2006060148A2/en
Publication of JP2008519858A publication Critical patent/JP2008519858A/ja
Publication of JP2008519858A5 publication Critical patent/JP2008519858A5/ja
Pending legal-status Critical Current

Links

JP2007541390A 2004-11-11 2005-11-11 エリスロポエチンレセプターに結合する新規ペプチド Pending JP2008519858A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62743304P 2004-11-11 2004-11-11
PCT/US2005/041113 WO2006060148A2 (en) 2004-11-11 2005-11-11 Novel peptides that bind to the erythropoietin receptor

Publications (2)

Publication Number Publication Date
JP2008519858A JP2008519858A (ja) 2008-06-12
JP2008519858A5 true JP2008519858A5 (enExample) 2008-12-18

Family

ID=36565509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007541390A Pending JP2008519858A (ja) 2004-11-11 2005-11-11 エリスロポエチンレセプターに結合する新規ペプチド

Country Status (12)

Country Link
US (2) US20090005292A1 (enExample)
EP (1) EP1814910A4 (enExample)
JP (1) JP2008519858A (enExample)
KR (1) KR20070108140A (enExample)
CN (1) CN101142234A (enExample)
AU (1) AU2005310189A1 (enExample)
CA (1) CA2587382A1 (enExample)
EA (1) EA200700990A1 (enExample)
IL (1) IL183123A0 (enExample)
MX (1) MX2007005777A (enExample)
NO (1) NO20072888L (enExample)
WO (1) WO2006060148A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2118127A4 (en) * 2007-01-31 2010-12-01 Affymax Inc NICKET-BASED LINKER FOR BONDING MODIFYING GROUPS OF POLYPEPTIDES AND OTHER MACROMOLECULES
CN101456911A (zh) * 2007-12-12 2009-06-17 江苏豪森药业股份有限公司 促红细胞生成素模拟肽衍生物及其可药用盐和其制备方法与用途
KR101148191B1 (ko) * 2011-09-27 2012-05-23 김후정 에리스로포이에틴-유래 펩타이드 및 그 용도
EP3432908A4 (en) * 2016-03-21 2020-07-29 Rhode Island Council on Postsecondary Education PEPTIDES SENSITIVE TO PH
AU2020396647A1 (en) * 2019-12-06 2022-07-07 Ajinomoto Co., Inc. Method for producing peptide having physiological activity, and peptide comprising short linker

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US633031A (en) * 1898-05-02 1899-09-12 Gas Motoren Fabrik Deutz Process of making gas.
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
KR850004274A (ko) * 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4677195A (en) * 1985-01-11 1987-06-30 Genetics Institute, Inc. Method for the purification of erythropoietin and erythropoietin compositions
NL8720442A (nl) * 1986-08-18 1989-04-03 Clinical Technologies Ass Afgeefsystemen voor farmacologische agentia.
US5080891A (en) * 1987-08-03 1992-01-14 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
US5006333A (en) * 1987-08-03 1991-04-09 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
WO1990008822A1 (en) * 1989-02-03 1990-08-09 Genetics Institute, Inc. Erythropoietin receptor
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
US5292654A (en) * 1990-12-13 1994-03-08 Whitehead Institute For Biomedical Research Mutant EPO receptor and uses therefor
AU643141B2 (en) * 1991-03-15 1993-11-04 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5770358A (en) * 1991-09-18 1998-06-23 Affymax Technologies N.V. Tagged synthetic oligomer libraries
US6153407A (en) * 1992-07-28 2000-11-28 Beth Israel Deaconess Medical Center Erythropoietin DNA having modified 5' and 3' sequences and its use to prepare EPO therapeutics
US5614184A (en) * 1992-07-28 1997-03-25 New England Deaconess Hospital Recombinant human erythropoietin mutants and therapeutic methods employing them
US5919455A (en) * 1993-10-27 1999-07-06 Enzon, Inc. Non-antigenic branched polymer conjugates
US5830851A (en) * 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5773569A (en) * 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
US5747446A (en) * 1994-03-22 1998-05-05 Beth Israel Deaconess Medical Center Modified polypeptides with increased biological activity
US5580853A (en) * 1994-03-22 1996-12-03 New England Deaconess Hospital Modified polypeptides with increased biological activity
US5919758A (en) * 1994-03-22 1999-07-06 Beth Israel Deaconess Medical Center Modified polypeptides with altered biological activity
US5451569A (en) * 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
US5654276A (en) * 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
US5677280A (en) * 1995-06-07 1997-10-14 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
EP0886648B8 (en) * 1995-06-07 2004-03-03 Ortho Pharmaceutical Corporation Compounds and peptides that bind to the erythropoietin receptor
ES2303338T3 (es) * 1995-06-07 2008-08-01 Glaxo Group Limited Peptidos y compuestos que se unen a un receptor de trombopoyetina.
US5767078A (en) * 1995-06-07 1998-06-16 Johnson; Dana L. Agonist peptide dimers
US5683983A (en) * 1995-06-07 1997-11-04 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
US5668110A (en) * 1995-06-07 1997-09-16 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
US5672662A (en) * 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US6346390B1 (en) * 1996-03-08 2002-02-12 Receptron, Inc. Receptor derived peptides involved in modulation of response to ligand binding
US6103879A (en) * 1996-06-21 2000-08-15 Axys Pharmaceuticals, Inc. Bivalent molecules that form an activating complex with an erythropoietin receptor
AU3908597A (en) * 1996-08-02 1998-02-25 Ortho-Mcneil Pharmaceutical, Inc. Polypeptides having a single covalently bound n-terminal water-soluble polymer
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
US6221608B1 (en) * 1997-01-22 2001-04-24 Ortho Pharmaceutical Corporation Methods for identifying erythropoietin receptor binding protein
US6074097A (en) * 1997-04-28 2000-06-13 Dai Nippon Printing Co., Ltd. Package, package manufacturing method and package manufacturing system for carrying out the package manufacturing method
JP4304757B2 (ja) * 1998-04-24 2009-07-29 株式会社デンソー Ａｂｓアクチュエータ
US6783965B1 (en) * 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
CA2338665C (en) * 1998-08-06 2011-01-18 Mountain View Pharmaceuticals, Inc. Peg-urate oxidase conjugates and use thereof
DE69936322T2 (de) * 1998-08-28 2008-02-21 Amylin Pharmaceuticals, Inc., San Diego Polyamideketten von genauer Länge und deren Konjugate mit Proteinen
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
AU1732900A (en) * 1998-11-17 2000-06-05 Ligand Pharmaceuticals Incorporated Methods of treating thrombocytopenia
JO2291B1 (en) * 1999-07-02 2005-09-12 اف . هوفمان لاروش ايه جي Erythropoietin derivatives
CZ299516B6 (cs) * 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
AUPQ873300A0 (en) * 2000-07-12 2000-08-03 Medvet Science Pty. Ltd. A binding motif of a receptor (2)
DE60032783T2 (de) * 1999-09-24 2007-12-06 Smithkline Beecham Corp. Thrombopoietinmimetika
DE60025241T2 (de) * 1999-09-27 2007-01-11 Chugai Seiyaku K.K. HäMOPOIETINREZEPTOR-PROTEIN, NR12
US6703480B1 (en) * 1999-11-24 2004-03-09 Palani Balu Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use
US6858630B2 (en) * 1999-12-06 2005-02-22 Smithkline Beecham Corporation Naphthimidazole derivatives and their use as thrombopoietin mimetics
JP2004512258A (ja) * 2000-03-21 2004-04-22 ウィスコンシン　アルムニ　リサーチ　ファンデイション 生物系における細胞応答の調節のための方法および試薬
US6777387B2 (en) * 2000-03-31 2004-08-17 Enzon Pharmaceuticals, Inc. Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
ATE291436T2 (de) * 2000-05-15 2005-04-15 Hoffmann La Roche Flüssige arzneizubereitung enthaltend ein erythropoietin derivat
CZ2003311A3 (cs) * 2000-08-02 2004-04-14 Ortho-Mcneil Pharmaceutical, Inc. Protivirová a protinádorová terapie za použití erythropoetinu
AU2001273385B2 (en) * 2000-09-08 2005-04-07 Gryphon Therapeutics, Inc. Polymer-modified synthetic proteins
MXPA03005406A (es) * 2000-12-20 2003-09-25 Hoffmann La Roche Conjugados de eritropoyetina.
US7767643B2 (en) * 2000-12-29 2010-08-03 The Kenneth S. Warren Institute, Inc. Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
US6531121B2 (en) * 2000-12-29 2003-03-11 The Kenneth S. Warren Institute, Inc. Protection and enhancement of erythropoietin-responsive cells, tissues and organs
FR2823220B1 (fr) * 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
US20020169128A1 (en) * 2001-04-09 2002-11-14 Geroge Sigounas Erythropoietin ameliorates chemotherapy-induced toxicity in vivo
DE60229958D1 (de) * 2001-06-28 2009-01-02 Mountain View Pharmaceuticals Polymerstabilisierte proteinasen
US6784154B2 (en) * 2001-11-01 2004-08-31 University Of Utah Research Foundation Method of use of erythropoietin to treat ischemic acute renal failure
US20050176627A1 (en) * 2002-09-09 2005-08-11 Anthony Cerami Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin
US8129330B2 (en) * 2002-09-30 2012-03-06 Mountain View Pharmaceuticals, Inc. Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
RS20050502A (sr) * 2002-12-26 2007-08-03 Mountain View Pharmaceuticals Inc., Polimerni konjugati interferona- beta sa povećanom biološkom aktivnošću
PL396711A1 (pl) * 2002-12-26 2011-12-19 Mountain View Pharmaceuticals, Inc. Koniugaty polimerów z cytokinami, chemokinami, czynnikami wzrostu, hormonami polipeptydowymi i ich antagonistami, kompozycja farmaceutyczna i sposób zapobiegania, diagnozowania lub leczenia
PT1629007E (pt) * 2003-05-12 2009-05-06 Affymax Inc Péptidos novos que se ligam ao receptor da eritropoietina

Similar Documents

Publication Publication Date Title
HRP20120989T1 (hr) Peptidi koji se vežu za receptor eritropoetina
ES2170042T3 (es) Procedimiento para la preparacion de cadenas de poliamida de longitud precisa y sus conjugados con proteinas.
CN100379760C (zh) 与受体结合的肽和化合物
JP6342556B2 (ja) 治療薬送達のための可溶性疎水性コア担体組成物、およびその製造・使用方法
CN104906594B (zh) 用于与蛋白质和肽缀合的四个支链的树枝状大分子peg
US20110306657A1 (en) Polyalkyleneimine-graft-biodegradable polymers for delivery of bioactive agents
US20100004390A1 (en) Biodegradable metal-chelating polymers and vaccines
JP2010503706A (ja) リジン系ポリマーリンカー
JP2008542399A5 (enExample)
US10155050B2 (en) Cross-linked star-shaped self-assembled polypeptides and its use as carriers in biomedical applications
JP2007504169A5 (enExample)
JP2008519858A5 (enExample)
Pechar et al. Poly (ethylene glycol)-based polymer carrier of doxorubicin degradable by both enzymatic and chemical hydrolyses
CN117940484A (zh) 星形pAsp-低聚胺衍生物
KR101200176B1 (ko) 풀루란 유도체?폴리에틸렌이민 접합체를 포함하는 생리활성 물질 전달체 및 이의 제조방법
EP1400551B1 (en) Polyamide chains of precise length and their conjugates with proteins
US12448488B2 (en) Conjugate of bio-related substance and block polymer, and block polymer derivative for obtaining said conjugate
CN118388578A (zh) 一种用于聚乙二醇化蛋白质的方法、非共价聚乙二醇化蛋白及含有其的蛋白质药物和应用
Sedlacek et al. Poly (2-oxazoline) eprotein
JPH10509208A (ja) 部位特異的結合のための官能化されたポリマー
Hudecz Design of Synthetic Branched Chain Polymeric Polypeptides for Targeting/Delivering Bioactive Molecules