JP2008519794A5 - - Google Patents

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Publication number
JP2008519794A5
JP2008519794A5 JP2007540588A JP2007540588A JP2008519794A5 JP 2008519794 A5 JP2008519794 A5 JP 2008519794A5 JP 2007540588 A JP2007540588 A JP 2007540588A JP 2007540588 A JP2007540588 A JP 2007540588A JP 2008519794 A5 JP2008519794 A5 JP 2008519794A5
Authority
JP
Japan
Prior art keywords
pyrimidine
benzo
furo
chloro
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007540588A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008519794A (ja
Filing date
Publication date
Priority claimed from GB0424972A external-priority patent/GB0424972D0/en
Priority claimed from EP05022665A external-priority patent/EP1776982A1/en
Application filed filed Critical
Priority claimed from PCT/EP2005/012087 external-priority patent/WO2006050965A1/en
Publication of JP2008519794A publication Critical patent/JP2008519794A/ja
Publication of JP2008519794A5 publication Critical patent/JP2008519794A5/ja
Withdrawn legal-status Critical Current

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JP2007540588A 2004-11-11 2005-11-11 ピリミジン化合物 Withdrawn JP2008519794A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0424972A GB0424972D0 (en) 2004-11-11 2004-11-11 Pyrimidine compounds
EP05022665A EP1776982A1 (en) 2005-10-18 2005-10-18 Pyrimidine compounds as histamine modulators
PCT/EP2005/012087 WO2006050965A1 (en) 2004-11-11 2005-11-11 Pyrimidine compounds as histamine modulators

Publications (2)

Publication Number Publication Date
JP2008519794A JP2008519794A (ja) 2008-06-12
JP2008519794A5 true JP2008519794A5 (enExample) 2008-12-25

Family

ID=35658998

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007540588A Withdrawn JP2008519794A (ja) 2004-11-11 2005-11-11 ピリミジン化合物

Country Status (6)

Country Link
US (1) US20080269239A1 (enExample)
EP (1) EP1812113A1 (enExample)
JP (1) JP2008519794A (enExample)
AU (1) AU2005303893A1 (enExample)
CA (1) CA2586316A1 (enExample)
WO (1) WO2006050965A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8067433B2 (en) 2005-11-09 2011-11-29 Zalicus Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
EP1860109A1 (en) * 2006-05-24 2007-11-28 Cellzome (UK) Ltd. Azetidine amino pyrimidine compounds for the treatment of inflammatory disorders
WO2007090854A1 (en) * 2006-02-10 2007-08-16 Cellzome (Uk) Ltd. Azetidine amino pyrimidine compounds for the treatment of inflammatory disorders
TW200815054A (en) * 2006-06-19 2008-04-01 Otsuka Pharma Co Ltd Methods of using a thiazole derivative
ES2441958T3 (es) * 2006-07-11 2014-02-07 Janssen Pharmaceutica Nv Moduladores de benzofuro- y benzotienopirimidina del receptor de histamina H4
US8735411B2 (en) 2006-10-02 2014-05-27 Abbvie Inc. Macrocyclic benzofused pyrimidine derivatives
US7985745B2 (en) 2006-10-02 2011-07-26 Abbott Laboratories Method for pain treatment
TW200924781A (en) 2007-09-14 2009-06-16 Janssen Pharmaceutica Nv Thieno- and furo-pyrimidine modulators of the histamine H4 receptor
PE20090978A1 (es) * 2007-10-30 2009-07-13 Palau Pharma Sa DERIVADOS DE FURO {3,2-d} PIRIMIDINA
AR069869A1 (es) * 2007-12-21 2010-02-24 Exelixis Inc Derivados de benzofuro[3,2-d]pirimidinas inhibidores de proteinquinasas,composiciones farmaceuticas que los comprenden y usos de los mismos en el tratamiento del cancer.
EP2077263A1 (en) * 2008-01-02 2009-07-08 Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg Quinazolines and related heterocyclic compounds and their therapeutic use
US8278313B2 (en) 2008-03-11 2012-10-02 Abbott Laboratories Macrocyclic spiro pyrimidine derivatives
TW200951136A (en) * 2008-03-17 2009-12-16 Palau Pharma Sa Furo[3,2-d]pyrimidine derivatives
WO2009137492A1 (en) * 2008-05-05 2009-11-12 Abbott Laboratories Heteroaryl-fused macrocyclic pyrimidine derivatives
KR101600278B1 (ko) 2008-06-12 2016-03-08 얀센 파마슈티카 엔.브이. 히스타민 ｈ4 수용체의 다이아미노-피리딘, 피리미딘, 및 피리다진 조절제
EP2201982A1 (en) 2008-12-24 2010-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Histamine H4 receptor antagonists for the treatment of vestibular disorders
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
CN102762572A (zh) 2010-02-01 2012-10-31 诺瓦提斯公司 作为CRF-1受体拮抗剂的吡唑并[5,1b]*唑衍生物
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
EP2531490B1 (en) 2010-02-02 2014-10-15 Novartis AG Cyclohexyl amide derivatives as crf receptor antagonists
EA026134B1 (ru) 2010-12-16 2017-03-31 Ф. Хоффманн-Ля Рош Аг Трициклические ингибиторы pi3k и способы их применения
UY34094A (es) 2011-05-27 2013-01-03 Novartis Ag Derivados de la piperidina 3-espirocíclica como agonistas de receptores de la ghrelina
WO2013164790A1 (en) 2012-05-03 2013-11-07 Novartis Ag L-malate salt of 2, 7 - diaza - spiro [4.5 ] dec- 7 - yle derivatives and crystalline forms thereof as ghrelin receptor agonists
HUE039713T2 (hu) 2012-06-08 2019-02-28 Sensorion H4 receptor inhibitorok tinnitus kezelésére
CN109616572B (zh) 2013-03-26 2023-01-17 株式会社半导体能源研究所 发光装置
KR102287012B1 (ko) * 2014-05-28 2021-08-09 덕산네오룩스 주식회사 유기전기 소자용 화합물, 이를 이용한 유기전기소자 및 그 전자 장치
KR20250065420A (ko) 2015-12-25 2025-05-12 가부시키가이샤 한도오따이 에네루기 켄큐쇼 화합물, 발광 소자, 표시 장치, 전자 기기, 및 조명 장치
JP7030716B2 (ja) * 2016-05-09 2022-03-07 バイオガイア・エイビー アレルギー治療に有用な細菌株の選択
CN115275032B (zh) 2016-12-28 2025-12-23 株式会社半导体能源研究所 发光元件、有机化合物、发光装置、电子设备及照明装置
JP2019006763A (ja) 2017-06-22 2019-01-17 株式会社半導体エネルギー研究所 有機化合物、発光素子、発光装置、電子機器、および照明装置
WO2020142729A1 (en) * 2019-01-04 2020-07-09 BellBrook Labs Inhibitors of cgas activity as therapeutic agents
US20240059712A1 (en) * 2022-03-09 2024-02-22 Risen (Suzhou) Pharma Tech Co., Ltd. Bifunctional compounds and pharmaceutical uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755583A (en) * 1970-06-05 1973-08-28 Chas0!nhx
JPH06220059A (ja) * 1993-01-28 1994-08-09 Tanabe Seiyaku Co Ltd 縮合ピリミジン誘導体及びその製法
WO2002072548A2 (en) * 2001-03-09 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Heterocyclic compounds and their use as histamine h4 ligands.
AU2003272285A1 (en) * 2002-09-06 2004-03-29 Janssen Pharmaceutica, N.V. Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands
WO2005037825A2 (en) * 2003-10-14 2005-04-28 Arizona Board Of Regents On Behalf Of The University Of Arizona Protein kinase inhibitors

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