JP2008513469A5 - - Google Patents
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- Publication number
- JP2008513469A5 JP2008513469A5 JP2007532470A JP2007532470A JP2008513469A5 JP 2008513469 A5 JP2008513469 A5 JP 2008513469A5 JP 2007532470 A JP2007532470 A JP 2007532470A JP 2007532470 A JP2007532470 A JP 2007532470A JP 2008513469 A5 JP2008513469 A5 JP 2008513469A5
- Authority
- JP
- Japan
- Prior art keywords
- toremifene
- use according
- dose
- day
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005026 toremifene Drugs 0.000 claims 12
- XFCLJVABOIYOMF-QPLCGJKRSA-N toremifene Chemical compound C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 XFCLJVABOIYOMF-QPLCGJKRSA-N 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 10
- 239000007788 liquid Substances 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- IWEQQRMGNVVKQW-OQKDUQJOSA-N Toremifene citrate Chemical group OC(=O)CC(O)(C(O)=O)CC(O)=O.C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 IWEQQRMGNVVKQW-OQKDUQJOSA-N 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- -1 elixir Substances 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 238000002513 implantation Methods 0.000 claims 2
- 238000001361 intraarterial administration Methods 0.000 claims 2
- 238000010255 intramuscular injection Methods 0.000 claims 2
- 239000007927 intramuscular injection Substances 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 239000000829 suppository Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 229960004167 toremifene citrate Drugs 0.000 claims 2
- 208000033830 Hot Flashes Diseases 0.000 claims 1
- 206010060800 Hot flush Diseases 0.000 claims 1
- 239000003098 androgen Substances 0.000 claims 1
- 238000009167 androgen deprivation therapy Methods 0.000 claims 1
- 150000004677 hydrates Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/944,465 US20050080143A1 (en) | 2001-11-29 | 2004-09-20 | Treatment of androgen-deprivation induced osteoporosis |
| PCT/US2005/032998 WO2006033979A1 (en) | 2004-09-20 | 2005-09-19 | Treatment of androgen - deprivation induced osteoporosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008240566A Division JP2009029823A (ja) | 2004-09-20 | 2008-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008513469A JP2008513469A (ja) | 2008-05-01 |
| JP2008513469A5 true JP2008513469A5 (https=) | 2010-04-22 |
Family
ID=36090335
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007532470A Pending JP2008513469A (ja) | 2004-09-20 | 2005-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
| JP2008240566A Pending JP2009029823A (ja) | 2004-09-20 | 2008-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008240566A Pending JP2009029823A (ja) | 2004-09-20 | 2008-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050080143A1 (https=) |
| EP (2) | EP1935415A3 (https=) |
| JP (2) | JP2008513469A (https=) |
| KR (1) | KR20070059167A (https=) |
| CN (2) | CN101961327A (https=) |
| AU (1) | AU2005287113B2 (https=) |
| BR (1) | BRPI0515668A (https=) |
| CA (1) | CA2581159A1 (https=) |
| EA (1) | EA014309B1 (https=) |
| IL (1) | IL182091A0 (https=) |
| MX (1) | MX2007003272A (https=) |
| WO (1) | WO2006033979A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040092602A1 (en) * | 1998-05-07 | 2004-05-13 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| US20040176470A1 (en) * | 1998-05-07 | 2004-09-09 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
| US20040214898A1 (en) * | 2001-11-29 | 2004-10-28 | Steiner Mitchell S. | Methods for treating hot flashes |
| US20060270641A1 (en) * | 2005-05-31 | 2006-11-30 | Steiner Mitchell S | Method for chemoprevention of prostate cancer |
| CN116869944A (zh) * | 2023-08-15 | 2023-10-13 | 重庆士立德医药科技有限公司 | 一种托瑞米芬组合物及其制备方法 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2464203A (en) | 1943-05-21 | 1949-03-15 | Boots Pure Drug Co Ltd | Manufacture of dienoestrol |
| US2465505A (en) | 1944-12-05 | 1949-03-29 | Hoffmann La Roche | Process for the manufacture of 3, 4-di-(p-hydroxy-phenyl)-hexadiene-2, 4 |
| US2914562A (en) | 1957-08-06 | 1959-11-24 | Wm S Merrell Co | Amine derivatives of triphenylethanol |
| GB8508404D0 (en) * | 1985-03-30 | 1985-05-09 | Baylor College Medicine | Therapeutic compositions |
| US4897254A (en) * | 1984-09-21 | 1990-01-30 | The Dow Chemical Company | Radioactive compositions for the treatment of calcific tumors |
| US4729999A (en) * | 1984-10-12 | 1988-03-08 | Bcm Technologies | Antiestrogen therapy for symptoms of estrogen deficiency |
| FR2578113B1 (fr) * | 1985-02-25 | 1988-04-15 | Merlin Gerin | Declencheur statique numerique a fonctions optionnelles pour un disjoncteur electrique |
| US4895715A (en) * | 1988-04-14 | 1990-01-23 | Schering Corporation | Method of treating gynecomastia |
| ATE230994T1 (de) * | 1989-07-07 | 2003-02-15 | Endorech Inc | Methode zur behandlung androgenbedingter krankheiten |
| US5153622A (en) * | 1989-08-03 | 1992-10-06 | Asahi Kogaku Kogyo Kabushiki Kaisha | Pressure alarm for water-sealed camera |
| JPH06287885A (ja) * | 1991-04-15 | 1994-10-11 | Yamauchi Corp | 脱水プレス用エンドレスベルト |
| GB9207437D0 (en) * | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| TW303299B (https=) * | 1993-07-22 | 1997-04-21 | Lilly Co Eli | |
| TW403738B (en) * | 1994-08-12 | 2000-09-01 | Hoffmann La Roche | Tricyclic pyrazole derivatives |
| GB9418067D0 (en) * | 1994-09-07 | 1994-10-26 | Orion Yhtymae Oy | Triphenylethylenes for the prevention and treatment of osteoporosis |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| IL120262A (en) * | 1996-02-28 | 2001-01-28 | Pfizer | Droloxifene and derivatives thereof for use in increasing serum testosterone levels |
| EP0891421A4 (en) * | 1996-03-18 | 2001-07-25 | Univ Pennsylvania | BIOACTIVE SUBSTRATE MATERIAL FOR IMPROVED CELLULAR FIXATION AND FUNCTION |
| GB9712086D0 (en) * | 1997-06-10 | 1997-08-13 | Bp Chem Int Ltd | Process for preparing polyketones |
| US6096764A (en) * | 1997-08-21 | 2000-08-01 | Eli Lilly And Company | Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration |
| US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| US6632447B1 (en) * | 1998-05-07 | 2003-10-14 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| SI1003496T1 (en) * | 1998-05-07 | 2005-10-31 | The University Of Tennessee Research Corporation | Medicament for treating prostate intraepithelial neoplasia |
| US6413535B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| EP1102755B1 (en) * | 1998-08-07 | 2006-01-04 | Chiron Corporation | Substituted isoxazole derivatives as estrogen receptor modulators |
| US6165504A (en) * | 1998-09-23 | 2000-12-26 | Barr Laboratories, Inc. | Methods for treating hot flashes and improving the quality of life of castrated prostatic cancer patients |
| US6258802B1 (en) * | 1999-10-06 | 2001-07-10 | Medical College Of Hampton Roads | Corticoid therapy |
| BR0108107A (pt) * | 2000-01-28 | 2003-03-11 | Endorech Inc | Moduladores seletivos dos receptores de estrogênio em combinação com estrogênios; kits e composições farmacêuticas para praticar tal combinação; bem como a administração da referida combinação |
| US6855703B1 (en) * | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
| GB0012291D0 (en) * | 2000-05-23 | 2000-07-12 | Astrazeneca Ab | Pharmaceutical combination |
| US7067557B2 (en) * | 2000-05-26 | 2006-06-27 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
| WO2001091744A1 (en) * | 2000-05-26 | 2001-12-06 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
| MXPA02012605A (es) * | 2000-06-28 | 2003-05-14 | Squibb Bristol Myers Co | Moduladores selectivos del receptor androgeno y metodo para su identificacion, dise°o y uso. |
| US20030114420A1 (en) * | 2000-06-28 | 2003-06-19 | Salvati Mark E. | Fused cyclic modulators of nuclear hormone receptor function |
| WO2002002099A1 (en) * | 2000-07-05 | 2002-01-10 | Astrazeneca Ab | Pharmaceutical combination of an anti-androgen and tamoxifen for providing an anti-androgenic effect and aromatase inhibition |
| ATE288303T1 (de) * | 2000-11-30 | 2005-02-15 | Pfizer Prod Inc | Östrogen agonist-antagonist und testosteron enthaltende zusammensetzung zur behandlung abnehmender testosteronspiegel |
| US6413633B1 (en) * | 2001-04-18 | 2002-07-02 | Francis Patrick McCullough | Activated biregional fiber(s) |
| WO2002091993A2 (en) * | 2001-05-10 | 2002-11-21 | Merck & Co., Inc. | Estrogen receptor modulators |
| CA2447518A1 (en) * | 2001-05-17 | 2002-11-21 | Immunex Corporation | Therapeutic use of rank antagonists |
| CN1679956A (zh) * | 2001-11-29 | 2005-10-12 | Gtx公司 | 治疗因雄激素剥夺引起的症状 |
| US7524866B2 (en) * | 2001-11-29 | 2009-04-28 | Gtx, Inc. | Prevention and treatment of androgen—deprivation induced osteoporosis |
| US20040152733A1 (en) * | 2002-03-15 | 2004-08-05 | Wallace Owen Brendan | Duloxetine for treatment of hot flashes |
| KR20050049476A (ko) * | 2002-08-14 | 2005-05-25 | 파마시아 앤드 업존 캄파니 엘엘씨 | 홍조를 치료하기 위한 레복세틴의 용도 |
| TWI229242B (en) * | 2002-08-23 | 2005-03-11 | Asml Netherlands Bv | Lithographic projection apparatus and particle barrier for use in said apparatus |
| US7332525B2 (en) * | 2003-01-17 | 2008-02-19 | Castle Erik P | Method of treatment of prostate cancer and composition for treatment thereof |
| MXPA05011299A (es) * | 2003-04-30 | 2006-01-24 | Debiopharm Sa | Metodos y composiciones utilizando la hormona liberadora de la hormona gonadotropina. |
| US7048210B2 (en) * | 2003-05-21 | 2006-05-23 | Frank Clark | Showerhead with grooved water release ducts |
| US20060019989A1 (en) * | 2004-07-21 | 2006-01-26 | Steiner Mitchell S | Compositions comprising 5-alpha reductase inhibitors and SERMs and methods of use thereof |
-
2004
- 2004-09-20 US US10/944,465 patent/US20050080143A1/en not_active Abandoned
-
2005
- 2005-09-19 CN CN2010105026847A patent/CN101961327A/zh active Pending
- 2005-09-19 CN CN2005800390976A patent/CN101056621B/zh not_active Expired - Fee Related
- 2005-09-19 EP EP08153021A patent/EP1935415A3/en not_active Withdrawn
- 2005-09-19 MX MX2007003272A patent/MX2007003272A/es unknown
- 2005-09-19 CA CA002581159A patent/CA2581159A1/en not_active Abandoned
- 2005-09-19 KR KR1020077009072A patent/KR20070059167A/ko not_active Ceased
- 2005-09-19 JP JP2007532470A patent/JP2008513469A/ja active Pending
- 2005-09-19 EP EP05797480A patent/EP1796643A4/en not_active Withdrawn
- 2005-09-19 EA EA200700690A patent/EA014309B1/ru not_active IP Right Cessation
- 2005-09-19 BR BRPI0515668-8A patent/BRPI0515668A/pt not_active IP Right Cessation
- 2005-09-19 WO PCT/US2005/032998 patent/WO2006033979A1/en not_active Ceased
- 2005-09-19 AU AU2005287113A patent/AU2005287113B2/en not_active Expired - Fee Related
-
2007
- 2007-03-21 IL IL182091A patent/IL182091A0/en unknown
-
2008
- 2008-09-19 JP JP2008240566A patent/JP2009029823A/ja active Pending
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