JP2008513469A5 - - Google Patents
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- Publication number
- JP2008513469A5 JP2008513469A5 JP2007532470A JP2007532470A JP2008513469A5 JP 2008513469 A5 JP2008513469 A5 JP 2008513469A5 JP 2007532470 A JP2007532470 A JP 2007532470A JP 2007532470 A JP2007532470 A JP 2007532470A JP 2008513469 A5 JP2008513469 A5 JP 2008513469A5
- Authority
- JP
- Japan
- Prior art keywords
- toremifene
- use according
- dose
- day
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005026 toremifene Drugs 0.000 claims 12
- XFCLJVABOIYOMF-QPLCGJKRSA-N toremifene Chemical compound C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 XFCLJVABOIYOMF-QPLCGJKRSA-N 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 10
- 239000007788 liquid Substances 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- IWEQQRMGNVVKQW-OQKDUQJOSA-N Toremifene citrate Chemical group OC(=O)CC(O)(C(O)=O)CC(O)=O.C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 IWEQQRMGNVVKQW-OQKDUQJOSA-N 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- -1 elixir Substances 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 238000002513 implantation Methods 0.000 claims 2
- 238000001361 intraarterial administration Methods 0.000 claims 2
- 238000010255 intramuscular injection Methods 0.000 claims 2
- 239000007927 intramuscular injection Substances 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 239000000829 suppository Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 229960004167 toremifene citrate Drugs 0.000 claims 2
- 208000033830 Hot Flashes Diseases 0.000 claims 1
- 206010060800 Hot flush Diseases 0.000 claims 1
- 239000003098 androgen Substances 0.000 claims 1
- 238000009167 androgen deprivation therapy Methods 0.000 claims 1
- 150000004677 hydrates Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/944,465 US20050080143A1 (en) | 2001-11-29 | 2004-09-20 | Treatment of androgen-deprivation induced osteoporosis |
| PCT/US2005/032998 WO2006033979A1 (en) | 2004-09-20 | 2005-09-19 | Treatment of androgen - deprivation induced osteoporosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008240566A Division JP2009029823A (ja) | 2004-09-20 | 2008-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008513469A JP2008513469A (ja) | 2008-05-01 |
| JP2008513469A5 true JP2008513469A5 (https=) | 2010-04-22 |
Family
ID=36090335
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007532470A Pending JP2008513469A (ja) | 2004-09-20 | 2005-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
| JP2008240566A Pending JP2009029823A (ja) | 2004-09-20 | 2008-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008240566A Pending JP2009029823A (ja) | 2004-09-20 | 2008-09-19 | アンドロゲン除去によって生じる骨粗鬆症の治療 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050080143A1 (https=) |
| EP (2) | EP1935415A3 (https=) |
| JP (2) | JP2008513469A (https=) |
| KR (1) | KR20070059167A (https=) |
| CN (2) | CN101961327A (https=) |
| AU (1) | AU2005287113B2 (https=) |
| BR (1) | BRPI0515668A (https=) |
| CA (1) | CA2581159A1 (https=) |
| EA (1) | EA014309B1 (https=) |
| IL (1) | IL182091A0 (https=) |
| MX (1) | MX2007003272A (https=) |
| WO (1) | WO2006033979A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040186185A1 (en) * | 1998-05-07 | 2004-09-23 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| US20040092602A1 (en) * | 1998-05-07 | 2004-05-13 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
| US20040214898A1 (en) * | 2001-11-29 | 2004-10-28 | Steiner Mitchell S. | Methods for treating hot flashes |
| US20060270641A1 (en) * | 2005-05-31 | 2006-11-30 | Steiner Mitchell S | Method for chemoprevention of prostate cancer |
| CN116869944A (zh) * | 2023-08-15 | 2023-10-13 | 重庆士立德医药科技有限公司 | 一种托瑞米芬组合物及其制备方法 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2464203A (en) | 1943-05-21 | 1949-03-15 | Boots Pure Drug Co Ltd | Manufacture of dienoestrol |
| US2465505A (en) | 1944-12-05 | 1949-03-29 | Hoffmann La Roche | Process for the manufacture of 3, 4-di-(p-hydroxy-phenyl)-hexadiene-2, 4 |
| US2914562A (en) | 1957-08-06 | 1959-11-24 | Wm S Merrell Co | Amine derivatives of triphenylethanol |
| GB8508404D0 (en) * | 1985-03-30 | 1985-05-09 | Baylor College Medicine | Therapeutic compositions |
| US4897254A (en) * | 1984-09-21 | 1990-01-30 | The Dow Chemical Company | Radioactive compositions for the treatment of calcific tumors |
| US4729999A (en) * | 1984-10-12 | 1988-03-08 | Bcm Technologies | Antiestrogen therapy for symptoms of estrogen deficiency |
| FR2578113B1 (fr) * | 1985-02-25 | 1988-04-15 | Merlin Gerin | Declencheur statique numerique a fonctions optionnelles pour un disjoncteur electrique |
| US4895715A (en) * | 1988-04-14 | 1990-01-23 | Schering Corporation | Method of treating gynecomastia |
| HUT60139A (en) * | 1989-07-07 | 1992-08-28 | Endorecherche Inc | Process for producing pharmaceutical composition suitable for treating prostate cancer connected with androgen |
| US5153622A (en) * | 1989-08-03 | 1992-10-06 | Asahi Kogaku Kogyo Kabushiki Kaisha | Pressure alarm for water-sealed camera |
| JPH06287885A (ja) * | 1991-04-15 | 1994-10-11 | Yamauchi Corp | 脱水プレス用エンドレスベルト |
| GB9207437D0 (en) * | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| TW303299B (https=) * | 1993-07-22 | 1997-04-21 | Lilly Co Eli | |
| TW403738B (en) * | 1994-08-12 | 2000-09-01 | Hoffmann La Roche | Tricyclic pyrazole derivatives |
| GB9418067D0 (en) * | 1994-09-07 | 1994-10-26 | Orion Yhtymae Oy | Triphenylethylenes for the prevention and treatment of osteoporosis |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| IL120262A (en) * | 1996-02-28 | 2001-01-28 | Pfizer | Droloxifene and derivatives thereof for use in increasing serum testosterone levels |
| WO1997035000A1 (en) * | 1996-03-18 | 1997-09-25 | The Trustees Of The University Of Pennsylvania | Bioactive material substrate for enhanced cellular attachment and function |
| GB9712086D0 (en) * | 1997-06-10 | 1997-08-13 | Bp Chem Int Ltd | Process for preparing polyketones |
| US6096764A (en) * | 1997-08-21 | 2000-08-01 | Eli Lilly And Company | Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration |
| US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| SI1003496T1 (en) * | 1998-05-07 | 2005-10-31 | The University Of Tennessee Research Corporation | Medicament for treating prostate intraepithelial neoplasia |
| US6632447B1 (en) * | 1998-05-07 | 2003-10-14 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| US6413535B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| EP1102755B1 (en) * | 1998-08-07 | 2006-01-04 | Chiron Corporation | Substituted isoxazole derivatives as estrogen receptor modulators |
| US6165504A (en) * | 1998-09-23 | 2000-12-26 | Barr Laboratories, Inc. | Methods for treating hot flashes and improving the quality of life of castrated prostatic cancer patients |
| US6258802B1 (en) * | 1999-10-06 | 2001-07-10 | Medical College Of Hampton Roads | Corticoid therapy |
| CN1400904A (zh) * | 2000-01-28 | 2003-03-05 | 恩多研究公司 | 与雌激素联合的选择性雌激素受体调节剂 |
| US6855703B1 (en) * | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
| GB0012291D0 (en) * | 2000-05-23 | 2000-07-12 | Astrazeneca Ab | Pharmaceutical combination |
| US7067557B2 (en) * | 2000-05-26 | 2006-06-27 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
| JP2003534375A (ja) * | 2000-05-26 | 2003-11-18 | フィッチ，ハリー | 選択性抗エストロゲン薬を用いた男性におけるアンドロゲン欠乏症の治療法 |
| US20030114420A1 (en) * | 2000-06-28 | 2003-06-19 | Salvati Mark E. | Fused cyclic modulators of nuclear hormone receptor function |
| BR0111298A (pt) * | 2000-06-28 | 2005-05-10 | Bristol Myers Squibb Co | Moduladores seletivos dos receptores de andrógenos e métodos para identificação, projeto e uso dos mesmos |
| EP1324754A1 (en) * | 2000-07-05 | 2003-07-09 | AstraZeneca AB | Pharmaceutical combination of an anti-androgen and tamoxifen for providing an anti-androgenic effect and aromatase inhibition |
| ATE288303T1 (de) * | 2000-11-30 | 2005-02-15 | Pfizer Prod Inc | Östrogen agonist-antagonist und testosteron enthaltende zusammensetzung zur behandlung abnehmender testosteronspiegel |
| US6413633B1 (en) * | 2001-04-18 | 2002-07-02 | Francis Patrick McCullough | Activated biregional fiber(s) |
| WO2002091993A2 (en) * | 2001-05-10 | 2002-11-21 | Merck & Co., Inc. | Estrogen receptor modulators |
| US20030017151A1 (en) * | 2001-05-17 | 2003-01-23 | Dougall William C. | Therapeutic use of rank antagonists |
| MXPA04005112A (es) * | 2001-11-29 | 2005-04-29 | Gtx Inc | Prevencion y tratamiento de osteoporosis inducida por privacion de androgeno. |
| US7524866B2 (en) * | 2001-11-29 | 2009-04-28 | Gtx, Inc. | Prevention and treatment of androgen—deprivation induced osteoporosis |
| US20040152733A1 (en) * | 2002-03-15 | 2004-08-05 | Wallace Owen Brendan | Duloxetine for treatment of hot flashes |
| EP1530476A1 (en) * | 2002-08-14 | 2005-05-18 | Pharmacia & Upjohn Company LLC | Use of reboxetine for the treatment of hot flashes |
| US6838684B2 (en) * | 2002-08-23 | 2005-01-04 | Asml Netherlands B.V. | Lithographic projection apparatus and particle barrier for use therein |
| US7332525B2 (en) * | 2003-01-17 | 2008-02-19 | Castle Erik P | Method of treatment of prostate cancer and composition for treatment thereof |
| MXPA05011299A (es) * | 2003-04-30 | 2006-01-24 | Debiopharm Sa | Metodos y composiciones utilizando la hormona liberadora de la hormona gonadotropina. |
| US7048210B2 (en) * | 2003-05-21 | 2006-05-23 | Frank Clark | Showerhead with grooved water release ducts |
| US20060019989A1 (en) * | 2004-07-21 | 2006-01-26 | Steiner Mitchell S | Compositions comprising 5-alpha reductase inhibitors and SERMs and methods of use thereof |
-
2004
- 2004-09-20 US US10/944,465 patent/US20050080143A1/en not_active Abandoned
-
2005
- 2005-09-19 KR KR1020077009072A patent/KR20070059167A/ko not_active Ceased
- 2005-09-19 EP EP08153021A patent/EP1935415A3/en not_active Withdrawn
- 2005-09-19 JP JP2007532470A patent/JP2008513469A/ja active Pending
- 2005-09-19 EP EP05797480A patent/EP1796643A4/en not_active Withdrawn
- 2005-09-19 AU AU2005287113A patent/AU2005287113B2/en not_active Expired - Fee Related
- 2005-09-19 CA CA002581159A patent/CA2581159A1/en not_active Abandoned
- 2005-09-19 BR BRPI0515668-8A patent/BRPI0515668A/pt not_active IP Right Cessation
- 2005-09-19 CN CN2010105026847A patent/CN101961327A/zh active Pending
- 2005-09-19 MX MX2007003272A patent/MX2007003272A/es unknown
- 2005-09-19 WO PCT/US2005/032998 patent/WO2006033979A1/en not_active Ceased
- 2005-09-19 EA EA200700690A patent/EA014309B1/ru not_active IP Right Cessation
- 2005-09-19 CN CN2005800390976A patent/CN101056621B/zh not_active Expired - Fee Related
-
2007
- 2007-03-21 IL IL182091A patent/IL182091A0/en unknown
-
2008
- 2008-09-19 JP JP2008240566A patent/JP2009029823A/ja active Pending
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