JP2008508863A5 - - Google Patents
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- Publication number
- JP2008508863A5 JP2008508863A5 JP2007517517A JP2007517517A JP2008508863A5 JP 2008508863 A5 JP2008508863 A5 JP 2008508863A5 JP 2007517517 A JP2007517517 A JP 2007517517A JP 2007517517 A JP2007517517 A JP 2007517517A JP 2008508863 A5 JP2008508863 A5 JP 2008508863A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- virus
- lentiviral vector
- flaviviridae
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 24
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 241000710781 Flaviviridae Species 0.000 claims 17
- 239000012634 fragment Substances 0.000 claims 16
- 230000002163 immunogen Effects 0.000 claims 14
- 239000002299 complementary DNA Substances 0.000 claims 11
- 150000001413 amino acids Chemical class 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 108091033319 polynucleotide Proteins 0.000 claims 9
- 102000040430 polynucleotide Human genes 0.000 claims 9
- 239000002157 polynucleotide Substances 0.000 claims 9
- 241000725619 Dengue virus Species 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 101710117545 C protein Proteins 0.000 claims 6
- 101710204837 Envelope small membrane protein Proteins 0.000 claims 6
- 101710145006 Lysis protein Proteins 0.000 claims 6
- 210000003527 eukaryotic cell Anatomy 0.000 claims 6
- 101710172711 Structural protein Proteins 0.000 claims 5
- 241000710886 West Nile virus Species 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 5
- 101710091045 Envelope protein Proteins 0.000 claims 4
- 101710188315 Protein X Proteins 0.000 claims 4
- 102100021696 Syncytin-1 Human genes 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 101710144111 Non-structural protein 3 Proteins 0.000 claims 3
- 244000005700 microbiome Species 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 241000894007 species Species 0.000 claims 3
- 108700008783 Hepatitis C virus E1 Proteins 0.000 claims 2
- 101710125507 Integrase/recombinase Proteins 0.000 claims 2
- 101710085938 Matrix protein Proteins 0.000 claims 2
- 108010052285 Membrane Proteins Proteins 0.000 claims 2
- 102000018697 Membrane Proteins Human genes 0.000 claims 2
- 101710127721 Membrane protein Proteins 0.000 claims 2
- 108010067390 Viral Proteins Proteins 0.000 claims 2
- 239000013060 biological fluid Substances 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 239000012228 culture supernatant Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000000833 heterodimer Substances 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 1
- 208000001490 Dengue Diseases 0.000 claims 1
- 206010012310 Dengue fever Diseases 0.000 claims 1
- 241000711549 Hepacivirus C Species 0.000 claims 1
- 101710150344 Protein Rev Proteins 0.000 claims 1
- 108010046722 Thrombospondin 1 Proteins 0.000 claims 1
- 102100036034 Thrombospondin-1 Human genes 0.000 claims 1
- 241000711975 Vesicular stomatitis virus Species 0.000 claims 1
- 241000710772 Yellow fever virus Species 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 230000000840 anti-viral effect Effects 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000012876 carrier material Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 208000025729 dengue disease Diseases 0.000 claims 1
- 210000003494 hepatocyte Anatomy 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 230000010354 integration Effects 0.000 claims 1
- 210000003061 neural cell Anatomy 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
- 229940051021 yellow-fever virus Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0405366A FR2870126B1 (fr) | 2004-05-17 | 2004-05-17 | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| PCT/IB2005/001753 WO2005111221A1 (en) | 2004-05-17 | 2005-05-16 | Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008508863A JP2008508863A (ja) | 2008-03-27 |
| JP2008508863A5 true JP2008508863A5 (https=) | 2008-07-03 |
Family
ID=34945000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007517517A Pending JP2008508863A (ja) | 2004-05-17 | 2005-05-16 | フラビウイルス科ウイルスタンパク質発現のための組換えレンチウイルスベクター、及びワクチンとしてのそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20090214589A1 (https=) |
| EP (2) | EP1751291B1 (https=) |
| JP (1) | JP2008508863A (https=) |
| CN (1) | CN1981043B (https=) |
| BR (1) | BRPI0510016B8 (https=) |
| CA (1) | CA2564934C (https=) |
| FR (1) | FR2870126B1 (https=) |
| MX (1) | MXPA06013388A (https=) |
| WO (1) | WO2005111221A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1050210B (en) | 1999-10-12 | 2007-08-24 | Institut Pasteur | Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna |
| FR2870126B1 (fr) * | 2004-05-17 | 2009-07-17 | Pasteur Institut | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| US8222029B2 (en) * | 2005-05-16 | 2012-07-17 | Institut Pasteur | Lentiviral vector-based vaccine |
| CA2508266A1 (fr) | 2005-06-20 | 2006-12-20 | Institut Pasteur | Polypeptides chimeriques et leurs applications therapeutiques contre une infection a flaviviridae |
| ES2423518T3 (es) | 2006-12-22 | 2013-09-20 | Institut Pasteur | Células y metodología para generar virus de ARN de cadena de sentido negativo no segmentada |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| US20110262472A1 (en) * | 2008-04-22 | 2011-10-27 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| EP2666477A1 (en) | 2012-05-23 | 2013-11-27 | Theravectys | Lentiviral vectors containing an MHC class I promoter |
| EP2603799A4 (en) | 2010-08-12 | 2014-02-12 | Clontech Lab Inc | SIDEFLOW ASSAYS FOR NON-DIAGNOSTIC ANALYSIS |
| EP3031923A1 (en) * | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| WO2017083291A1 (en) | 2015-11-09 | 2017-05-18 | Immune Design Corp. | Compositions comprising lentiviral vectors expressing il-12 and methods of use thereof |
| EP3184119A1 (en) | 2015-12-23 | 2017-06-28 | Themis Bioscience GmbH | Chromatography based purification strategies for measles scaffold based viruses |
| SG11202004234SA (en) | 2017-11-09 | 2020-06-29 | Pasteur Institut | A zika virus chimeric polyepitope comprising non-structural proteins and its use in an immunogenic composition |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100317509B1 (ko) * | 1992-07-16 | 2002-02-20 | 야스모토 토루 | C형간염바이러스를분류하기위한항원성펩티드,이펩티드를포함하는키트및이펩티드를사용하는c형간염바이러스를분류하는방법 |
| US5883081A (en) | 1995-07-26 | 1999-03-16 | The Regents Of The University Of California | Isolation of novel HIV-2 proviruses |
| US5888767A (en) | 1996-11-27 | 1999-03-30 | The Johns Hopkins University School Of Medicine | Method of using a conditionally replicating viral vector to express a gene |
| PT904392E (pt) | 1996-10-17 | 2001-06-29 | Oxford Biomedica Ltd | Vectores retrovirais |
| ES2373406T3 (es) | 1997-12-22 | 2012-02-03 | Oxford Biomedica (Uk) Limited | Vectores basados en el virus de la anemia infecciosa equina (vaie). |
| WO1999036511A2 (en) * | 1998-01-16 | 1999-07-22 | Chiron Corporation | Feline immunodeficiency virus gene therapy vectors |
| FR2777909B1 (fr) * | 1998-04-24 | 2002-08-02 | Pasteur Institut | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| AU4554899A (en) | 1998-06-09 | 1999-12-30 | Andrea D. Branch | Novel hepatitis c virus peptides and uses thereof |
| US7052830B1 (en) * | 1998-06-09 | 2006-05-30 | Branch Andrea D | Hepatitis C virus peptides and uses thereof |
| FR2794865B1 (fr) | 1999-06-09 | 2003-04-18 | Pasteur Institut | Methode de detection precoce des flavivirus et ses applications |
| DE69941703D1 (de) | 1999-10-11 | 2010-01-07 | Pasteur Institut | Lentivirale Vektoren für die Herstellung von immunotherapeutischen Zusammensetzungen |
| HK1050210B (en) | 1999-10-12 | 2007-08-24 | Institut Pasteur | Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna |
| EP1092780A1 (en) | 1999-10-13 | 2001-04-18 | Boehringer Ingelheim International GmbH | Recombiant, replication defective CELO virus and CELO virus DNA |
| CA2443290C (fr) | 2001-04-04 | 2011-11-08 | Institut Pasteur | Souche neurovirulente du virus west-nile et ses applications |
| US20040037848A1 (en) | 2001-04-06 | 2004-02-26 | Audonnet Jean-Christophe Francis | Recombinant vaccine against West Nile Virus |
| HU228690B1 (en) | 2001-07-27 | 2013-05-28 | Wyeth Corp | West nile vaccine |
| CA2903126C (en) | 2002-01-10 | 2020-03-24 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Construction of west nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by west nile virus |
| US7476390B2 (en) * | 2002-02-26 | 2009-01-13 | Maxygen, Inc. | Flavivirus antigens |
| US20030194392A1 (en) | 2002-04-10 | 2003-10-16 | Pierre Charneau | Lentiviral triplex DNA, and vectors and recombinant cells containing lentiviral triplex DNA |
| DE10249594A1 (de) * | 2002-10-24 | 2004-05-13 | Jassoy, Christian, Dr. | Immunisierung gegen Bestandteile des Humanen Immunschwächevirus (HIV) |
| CA2456873A1 (en) * | 2003-02-26 | 2004-08-26 | Centre National De La Recherche Scientifique (C.N.R.S.) | West nile virus proteins and genes coding the foregoing and their use in vaccinal, therapeutic and diagnostic applications |
| CA2432738A1 (en) | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
| FR2870126B1 (fr) | 2004-05-17 | 2009-07-17 | Pasteur Institut | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| US8222029B2 (en) | 2005-05-16 | 2012-07-17 | Institut Pasteur | Lentiviral vector-based vaccine |
| US8158413B2 (en) | 2005-10-17 | 2012-04-17 | Institut Pasteur | Lentiviral vector-based vaccine |
-
2004
- 2004-05-17 FR FR0405366A patent/FR2870126B1/fr not_active Expired - Lifetime
-
2005
- 2005-05-16 MX MXPA06013388A patent/MXPA06013388A/es active IP Right Grant
- 2005-05-16 WO PCT/IB2005/001753 patent/WO2005111221A1/en not_active Ceased
- 2005-05-16 CN CN200580015744XA patent/CN1981043B/zh not_active Expired - Lifetime
- 2005-05-16 EP EP05748053.5A patent/EP1751291B1/en not_active Expired - Lifetime
- 2005-05-16 CA CA2564934A patent/CA2564934C/en not_active Expired - Lifetime
- 2005-05-16 EP EP11167507.0A patent/EP2371966B1/en not_active Expired - Lifetime
- 2005-05-16 JP JP2007517517A patent/JP2008508863A/ja active Pending
- 2005-05-16 BR BRPI0510016A patent/BRPI0510016B8/pt active IP Right Grant
- 2005-05-16 US US11/596,675 patent/US20090214589A1/en not_active Abandoned
-
2011
- 2011-01-07 US US12/929,215 patent/US8716013B2/en not_active Expired - Lifetime
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