CA2564934C - Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine - Google Patents
Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine Download PDFInfo
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- CA2564934C CA2564934C CA2564934A CA2564934A CA2564934C CA 2564934 C CA2564934 C CA 2564934C CA 2564934 A CA2564934 A CA 2564934A CA 2564934 A CA2564934 A CA 2564934A CA 2564934 C CA2564934 C CA 2564934C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
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- Biophysics (AREA)
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- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
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- Public Health (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0405366 | 2004-05-17 | ||
| FR0405366A FR2870126B1 (fr) | 2004-05-17 | 2004-05-17 | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| PCT/IB2005/001753 WO2005111221A1 (en) | 2004-05-17 | 2005-05-16 | Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2564934A1 CA2564934A1 (en) | 2005-11-24 |
| CA2564934C true CA2564934C (en) | 2014-07-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2564934A Expired - Lifetime CA2564934C (en) | 2004-05-17 | 2005-05-16 | Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20090214589A1 (https=) |
| EP (2) | EP1751291B1 (https=) |
| JP (1) | JP2008508863A (https=) |
| CN (1) | CN1981043B (https=) |
| BR (1) | BRPI0510016B8 (https=) |
| CA (1) | CA2564934C (https=) |
| FR (1) | FR2870126B1 (https=) |
| MX (1) | MXPA06013388A (https=) |
| WO (1) | WO2005111221A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| HK1050210B (en) | 1999-10-12 | 2007-08-24 | Institut Pasteur | Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna |
| FR2870126B1 (fr) * | 2004-05-17 | 2009-07-17 | Pasteur Institut | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| US8222029B2 (en) * | 2005-05-16 | 2012-07-17 | Institut Pasteur | Lentiviral vector-based vaccine |
| CA2508266A1 (fr) | 2005-06-20 | 2006-12-20 | Institut Pasteur | Polypeptides chimeriques et leurs applications therapeutiques contre une infection a flaviviridae |
| ES2423518T3 (es) | 2006-12-22 | 2013-09-20 | Institut Pasteur | Células y metodología para generar virus de ARN de cadena de sentido negativo no segmentada |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| US20110262472A1 (en) * | 2008-04-22 | 2011-10-27 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| EP2666477A1 (en) | 2012-05-23 | 2013-11-27 | Theravectys | Lentiviral vectors containing an MHC class I promoter |
| EP2603799A4 (en) | 2010-08-12 | 2014-02-12 | Clontech Lab Inc | SIDEFLOW ASSAYS FOR NON-DIAGNOSTIC ANALYSIS |
| EP3031923A1 (en) * | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| WO2017083291A1 (en) | 2015-11-09 | 2017-05-18 | Immune Design Corp. | Compositions comprising lentiviral vectors expressing il-12 and methods of use thereof |
| EP3184119A1 (en) | 2015-12-23 | 2017-06-28 | Themis Bioscience GmbH | Chromatography based purification strategies for measles scaffold based viruses |
| SG11202004234SA (en) | 2017-11-09 | 2020-06-29 | Pasteur Institut | A zika virus chimeric polyepitope comprising non-structural proteins and its use in an immunogenic composition |
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| KR100317509B1 (ko) * | 1992-07-16 | 2002-02-20 | 야스모토 토루 | C형간염바이러스를분류하기위한항원성펩티드,이펩티드를포함하는키트및이펩티드를사용하는c형간염바이러스를분류하는방법 |
| US5883081A (en) | 1995-07-26 | 1999-03-16 | The Regents Of The University Of California | Isolation of novel HIV-2 proviruses |
| US5888767A (en) | 1996-11-27 | 1999-03-30 | The Johns Hopkins University School Of Medicine | Method of using a conditionally replicating viral vector to express a gene |
| PT904392E (pt) | 1996-10-17 | 2001-06-29 | Oxford Biomedica Ltd | Vectores retrovirais |
| ES2373406T3 (es) | 1997-12-22 | 2012-02-03 | Oxford Biomedica (Uk) Limited | Vectores basados en el virus de la anemia infecciosa equina (vaie). |
| WO1999036511A2 (en) * | 1998-01-16 | 1999-07-22 | Chiron Corporation | Feline immunodeficiency virus gene therapy vectors |
| FR2777909B1 (fr) * | 1998-04-24 | 2002-08-02 | Pasteur Institut | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| AU4554899A (en) | 1998-06-09 | 1999-12-30 | Andrea D. Branch | Novel hepatitis c virus peptides and uses thereof |
| US7052830B1 (en) * | 1998-06-09 | 2006-05-30 | Branch Andrea D | Hepatitis C virus peptides and uses thereof |
| FR2794865B1 (fr) | 1999-06-09 | 2003-04-18 | Pasteur Institut | Methode de detection precoce des flavivirus et ses applications |
| DE69941703D1 (de) | 1999-10-11 | 2010-01-07 | Pasteur Institut | Lentivirale Vektoren für die Herstellung von immunotherapeutischen Zusammensetzungen |
| HK1050210B (en) | 1999-10-12 | 2007-08-24 | Institut Pasteur | Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna |
| EP1092780A1 (en) | 1999-10-13 | 2001-04-18 | Boehringer Ingelheim International GmbH | Recombiant, replication defective CELO virus and CELO virus DNA |
| CA2443290C (fr) | 2001-04-04 | 2011-11-08 | Institut Pasteur | Souche neurovirulente du virus west-nile et ses applications |
| US20040037848A1 (en) | 2001-04-06 | 2004-02-26 | Audonnet Jean-Christophe Francis | Recombinant vaccine against West Nile Virus |
| HU228690B1 (en) | 2001-07-27 | 2013-05-28 | Wyeth Corp | West nile vaccine |
| CA2903126C (en) | 2002-01-10 | 2020-03-24 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Construction of west nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by west nile virus |
| US7476390B2 (en) * | 2002-02-26 | 2009-01-13 | Maxygen, Inc. | Flavivirus antigens |
| US20030194392A1 (en) | 2002-04-10 | 2003-10-16 | Pierre Charneau | Lentiviral triplex DNA, and vectors and recombinant cells containing lentiviral triplex DNA |
| DE10249594A1 (de) * | 2002-10-24 | 2004-05-13 | Jassoy, Christian, Dr. | Immunisierung gegen Bestandteile des Humanen Immunschwächevirus (HIV) |
| CA2456873A1 (en) * | 2003-02-26 | 2004-08-26 | Centre National De La Recherche Scientifique (C.N.R.S.) | West nile virus proteins and genes coding the foregoing and their use in vaccinal, therapeutic and diagnostic applications |
| CA2432738A1 (en) | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
| FR2870126B1 (fr) | 2004-05-17 | 2009-07-17 | Pasteur Institut | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| US8222029B2 (en) | 2005-05-16 | 2012-07-17 | Institut Pasteur | Lentiviral vector-based vaccine |
| US8158413B2 (en) | 2005-10-17 | 2012-04-17 | Institut Pasteur | Lentiviral vector-based vaccine |
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2004
- 2004-05-17 FR FR0405366A patent/FR2870126B1/fr not_active Expired - Lifetime
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2005
- 2005-05-16 MX MXPA06013388A patent/MXPA06013388A/es active IP Right Grant
- 2005-05-16 WO PCT/IB2005/001753 patent/WO2005111221A1/en not_active Ceased
- 2005-05-16 CN CN200580015744XA patent/CN1981043B/zh not_active Expired - Lifetime
- 2005-05-16 EP EP05748053.5A patent/EP1751291B1/en not_active Expired - Lifetime
- 2005-05-16 CA CA2564934A patent/CA2564934C/en not_active Expired - Lifetime
- 2005-05-16 EP EP11167507.0A patent/EP2371966B1/en not_active Expired - Lifetime
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- 2005-05-16 BR BRPI0510016A patent/BRPI0510016B8/pt active IP Right Grant
- 2005-05-16 US US11/596,675 patent/US20090214589A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1751291B1 (en) | 2013-07-31 |
| BRPI0510016B1 (pt) | 2020-03-10 |
| CN1981043A (zh) | 2007-06-13 |
| US20090214589A1 (en) | 2009-08-27 |
| BRPI0510016A (pt) | 2007-09-18 |
| MXPA06013388A (es) | 2007-06-19 |
| CN1981043B (zh) | 2010-06-09 |
| WO2005111221A1 (en) | 2005-11-24 |
| CA2564934A1 (en) | 2005-11-24 |
| FR2870126A1 (fr) | 2005-11-18 |
| BRPI0510016B8 (pt) | 2021-05-25 |
| EP1751291A1 (en) | 2007-02-14 |
| EP2371966B1 (en) | 2015-11-25 |
| US8716013B2 (en) | 2014-05-06 |
| EP2371966A1 (en) | 2011-10-05 |
| JP2008508863A (ja) | 2008-03-27 |
| US20110206710A1 (en) | 2011-08-25 |
| FR2870126B1 (fr) | 2009-07-17 |
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