|
AU2004315596B2
(en)
*
|
2003-08-29 |
2011-11-24 |
President And Fellows Of Harvard College |
Inhibitors of cellular necrosis
|
|
SE0302573D0
(sv)
|
2003-09-26 |
2003-09-26 |
Astrazeneca Ab |
Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
|
|
DE10354060A1
(de)
*
|
2003-11-19 |
2005-06-02 |
Merck Patent Gmbh |
Pyrrolderivate
|
|
US8415354B2
(en)
|
2004-04-29 |
2013-04-09 |
Abbott Laboratories |
Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US7880001B2
(en)
|
2004-04-29 |
2011-02-01 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
|
US20100222316A1
(en)
|
2004-04-29 |
2010-09-02 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
WO2006012642A2
(en)
*
|
2004-07-30 |
2006-02-02 |
Exelixis, Inc. |
Pyrrole derivatives as pharmaceutical agents
|
|
BRPI0515897A
(pt)
|
2004-09-24 |
2008-08-12 |
Astrazeneca Ab |
composto, uso do mesmo, composição farmacêutica, e, método para a terapia de dor em um animal de sangue quente, e para a preparação de um composto
|
|
US20090192198A1
(en)
|
2005-01-05 |
2009-07-30 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US7217838B2
(en)
|
2005-01-05 |
2007-05-15 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US8198331B2
(en)
|
2005-01-05 |
2012-06-12 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US7511175B2
(en)
|
2005-01-05 |
2009-03-31 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
JP5123668B2
(ja)
*
|
2005-01-10 |
2013-01-23 |
エグゼリクシス, インコーポレイテッド |
医薬品としての複素環カルボキサミド化合物
|
|
TW200745049A
(en)
|
2006-03-23 |
2007-12-16 |
Astrazeneca Ab |
New crystalline forms
|
|
TW200808769A
(en)
|
2006-04-18 |
2008-02-16 |
Astrazeneca Ab |
Therapeutic compounds
|
|
HRP20120078T1
(hr)
|
2006-10-31 |
2012-02-29 |
Pfizer Products Inc. |
Pirazolinski spojevi kao antagonisti mineralokortikoidnih receptora
|
|
PT2133330E
(pt)
*
|
2007-04-09 |
2014-03-31 |
Daiichi Sankyo Co Ltd |
Atropisómero de derivado de pirrole
|
|
WO2009023272A1
(en)
*
|
2007-08-15 |
2009-02-19 |
President And Fellows Of Harvard College |
Heterocyclic inhibitors of necroptosis
|
|
JP5736098B2
(ja)
|
2007-08-21 |
2015-06-17 |
アッヴィ・インコーポレイテッド |
中枢神経系障害を治療するための医薬組成物
|
|
BRPI0815668A2
(pt)
*
|
2007-08-22 |
2017-05-23 |
Allergan Inc |
compostos pirrol tendo atividade biológica antagonista e agonista de receptor de esfingosina-1-fosfato.
|
|
CA2699157A1
(en)
|
2007-09-10 |
2009-03-19 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
WO2009076454A2
(en)
*
|
2007-12-12 |
2009-06-18 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
CA2720164A1
(en)
*
|
2008-03-31 |
2009-10-08 |
Teva Pharmaceutical Industries Ltd. |
Processes for preparing sunitinib and salts thereof
|
|
GB0808282D0
(en)
*
|
2008-05-07 |
2008-06-11 |
Medical Res Council |
Compounds for use in stabilizing p53 mutants
|
|
HRP20170019T1
(hr)
|
2008-08-15 |
2017-03-10 |
Nivalis Therapeutics, Inc. |
Novi pirol-inhibitori od reduktaze s-nitrozoglutationa kao terapeutska sredstva
|
|
WO2010019909A1
(en)
|
2008-08-15 |
2010-02-18 |
N30 Pharmaceuticals, Llc |
Pyrrole inhibitors of s-nitrosoglutathione reductase
|
|
EP2318007B1
(en)
|
2008-08-15 |
2013-01-23 |
N30 Pharmaceuticals, Inc. |
Novel pyrrole inhibitors of s-nitrosoglutathione reductase as therapeutic agents
|
|
KR101724161B1
(ko)
*
|
2008-08-27 |
2017-04-06 |
칼시메디카, 인크 |
세포내 칼슘을 조절하는 화합물
|
|
US8524763B2
(en)
|
2008-09-22 |
2013-09-03 |
Calcimedica, Inc. |
Inhibitors of store operated calcium release
|
|
ES2453500T3
(es)
*
|
2008-10-08 |
2014-04-08 |
Exelixis, Inc. |
Compuestos de 1-fenilpirrol
|
|
CA2736923C
(en)
*
|
2008-10-08 |
2016-11-22 |
Exelixis Inc. |
Atropisomers of (hydroxyalkyl) pyrrole derivatives
|
|
US20120122889A1
(en)
|
2008-12-23 |
2012-05-17 |
President And Fellows Of Harvard College |
Small molecule inhibitors of necroptosis
|
|
WO2010107476A1
(en)
*
|
2009-03-19 |
2010-09-23 |
Duke University |
Inhibiting gsnor
|
|
EP2427452A4
(en)
*
|
2009-05-05 |
2012-09-26 |
Merck Sharp & Dohme |
P38 KINASE-INHIBITABLE ACTIVE SUBSTANCES
|
|
EP2253617A1
(de)
*
|
2009-05-20 |
2010-11-24 |
Bayer CropScience AG |
Halogen-substituierte Verbindungen als Pestizide
|
|
EP2470183B1
(en)
*
|
2009-08-26 |
2015-09-16 |
Merck Sharp & Dohme Corp. |
Heterocyclic amide compounds as protein kinase inhibitors
|
|
US8618307B2
(en)
*
|
2009-09-16 |
2013-12-31 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
AR079967A1
(es)
*
|
2010-01-26 |
2012-02-29 |
Sanofi Aventis |
Derivados de acido 3-heteroaroilamino-propionico sustituidos con oxigeno y su uso como productos farmaceuticos
|
|
EP2977084B1
(en)
|
2010-05-10 |
2017-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for the treatment of fluid accumulation in and/ or under the retina
|
|
WO2011157798A1
(en)
|
2010-06-16 |
2011-12-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for stimulating reepithelialisation during wound healing
|
|
WO2012027710A2
(en)
|
2010-08-27 |
2012-03-01 |
Calcimedica Inc. |
Compounds that modulate intracellular calcium
|
|
WO2012061926A1
(en)
*
|
2010-11-08 |
2012-05-18 |
Zalicus Pharmaceuticals Ltd. |
Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers
|
|
EP2800745B1
(en)
|
2011-12-02 |
2020-02-12 |
Phenex Pharmaceuticals AG |
Pyrrolo carboxamides as modulators of orphan nuclear receptor rar-related orphan receptor-gamma (rory, nr1f3) activity and for the treatment of chronic inflammatory and autoimmune diseases
|
|
EA026368B1
(ru)
|
2011-12-21 |
2017-03-31 |
Новира Терапьютикс, Инк. |
Противовирусные агенты против гепатита в
|
|
AU2013307337B2
(en)
|
2012-08-28 |
2018-07-19 |
Janssen Sciences Ireland Uc |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of Hepatitis B
|
|
US9512116B2
(en)
|
2012-10-12 |
2016-12-06 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
CN105189453B
(zh)
|
2013-02-28 |
2018-04-10 |
爱尔兰詹森科学公司 |
氨磺酰基‑芳基酰胺及其作为用于乙型肝炎治疗的药物的用途
|
|
WO2014145022A1
(en)
|
2013-03-15 |
2014-09-18 |
President And Fellows Of Harvard College |
Hybrid necroptosis inhibitors
|
|
WO2014161888A1
(en)
|
2013-04-03 |
2014-10-09 |
Janssen R&D Ireland |
N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
HUE038950T2
(hu)
|
2013-04-10 |
2018-12-28 |
Daiichi Sankyo Co Ltd |
Eljárás pirrol származék atropizomere elõállítására
|
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
|
BR112015028538A2
(pt)
|
2013-05-17 |
2017-07-25 |
Janssen Sciences Ireland Uc |
derivados de sulfamoiltiofenamida e o uso dos mesmos como medicamentos para o tratamento da hepatite b
|
|
JP6422868B2
(ja)
*
|
2013-07-23 |
2018-11-14 |
第一三共株式会社 |
高血圧症の予防又は治療のための医薬
|
|
CA2935719C
(en)
|
2013-07-25 |
2021-11-02 |
Janssen Sciences Ireland Uc |
Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
HUE037007T2
(hu)
|
2013-08-27 |
2018-08-28 |
Daiichi Sankyo Co Ltd |
Eljárás pirrol származék elõállítására és annak intermediere
|
|
AU2014338947B2
(en)
|
2013-10-23 |
2018-02-22 |
Janssen Sciences Ireland Uc |
Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
WO2015083130A1
(en)
*
|
2013-12-06 |
2015-06-11 |
Aurigene Discovery Technologies Limited |
Fused pyridine and pyrimidine derivatives as ror gamma modulators
|
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
KR20160128305A
(ko)
|
2014-02-05 |
2016-11-07 |
노비라 테라퓨틱스, 인코포레이티드 |
Hbv 감염의 치료를 위한 병용 요법
|
|
JP6495929B2
(ja)
|
2014-02-06 |
2019-04-03 |
ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー |
スルファモイルピロールアミド誘導体およびb型肝炎の治療のための医薬としてのその使用
|
|
MX2017007607A
(es)
|
2014-12-11 |
2018-05-28 |
Harvard College |
Inhibidores de necrosis celular y metodos relacionados.
|
|
WO2016121664A1
(ja)
*
|
2015-01-26 |
2016-08-04 |
第一三共株式会社 |
ピロールカルボキサミドの固形組成物
|
|
WO2016172496A1
(en)
|
2015-04-23 |
2016-10-27 |
Constellation Pharmaceuticals, Inc. |
Lsd1 inhibitors and uses thereof
|
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
TWI623316B
(zh)
*
|
2015-12-22 |
2018-05-11 |
Taiho Pharmaceutical Co Ltd |
Antitumor effect enhancer derived from pyrrolopyrimidine compound
|
|
EP3423452B1
(en)
*
|
2016-03-01 |
2025-05-07 |
University of Maryland, Baltimore |
Wnt signaling pathway inhibitors for treatments of disease
|
|
CA3015964C
(en)
|
2016-03-24 |
2021-08-03 |
Daiichi Sankyo Company, Limited |
Medicine for treating renal disease
|
|
BR112018071048A2
(pt)
|
2016-04-15 |
2019-05-07 |
Janssen Sciences Ireland Uc |
combinações e métodos que compreendem um inibidor da montagem de capsídeos
|
|
EP3525778A1
(de)
|
2016-10-11 |
2019-08-21 |
Bayer Pharma Aktiengesellschaft |
Kombination enthaltend sgc aktivatoren und mineralocorticoid-rezeptor-antagonisten
|
|
CN110022871A
(zh)
|
2016-10-11 |
2019-07-16 |
拜耳制药股份公司 |
包含sGC刺激物和盐皮质激素受体拮抗剂的组合产品
|
|
HUE063848T2
(hu)
|
2016-10-26 |
2024-02-28 |
Constellation Pharmaceuticals Inc |
LSD1 gátlók és gyógyászati alkalmazásaik
|
|
WO2018153898A1
(de)
|
2017-02-22 |
2018-08-30 |
Bayer Pharma Aktiengesellschaft |
Selektive partielle adenosin a1 rezeptor-agonisten in kombination mit mineralocorticoid-rezeptor-antagonisten
|
|
DE102017008472A1
(de)
|
2017-09-08 |
2018-05-03 |
Bayer Pharma Aktiengesellschaft |
Kombination enthaltend PDE5 Inhibitoren und Mineralocorticoid-Rezeptor-Antagonisten
|
|
MA52019A
(fr)
|
2018-03-14 |
2021-01-20 |
Janssen Sciences Ireland Unlimited Co |
Schéma posologique de modulateur d'assemblage de capside
|
|
US11597716B2
(en)
|
2018-03-30 |
2023-03-07 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition thereof, and use thereof
|
|
EA202092159A1
(ru)
|
2019-01-25 |
2020-12-15 |
Чиа Тай Тянцин Фармасьютикал Груп Ко., Лтд. |
Содержащий n-гетероциклическое пятичленное кольцо ингибитор сборки капсидного белка, его фармацевтическая композиция и их применение
|
|
CA3127152A1
(en)
|
2019-02-22 |
2020-08-27 |
Janssen Sciences Ireland Unlimited Company |
Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases
|
|
US11491148B2
(en)
|
2019-05-06 |
2022-11-08 |
Janssen Sciences Ireland Unlimited Company |
Amide derivatives useful in the treatment of HBV infection or HBV-induced diseases
|
|
CN114466837B
(zh)
|
2019-09-29 |
2024-05-31 |
正大天晴药业集团股份有限公司 |
N杂五元环化合物的晶型及其应用
|
|
CA3156070A1
(en)
|
2019-09-29 |
2021-04-01 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Crystalline form of capsid protein assembly inhibitor containing n hetero five-membered ring, and application thereof
|
|
CN112707854B
(zh)
*
|
2019-10-25 |
2022-03-15 |
年衍药业(珠海)有限公司 |
吡咯酰胺类化合物及其用途
|
|
RU2738405C1
(ru)
*
|
2020-05-26 |
2020-12-11 |
Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" |
АМИД (Е)-2-АМИНО-4-ОКСО-5-(2-ОКСО-2-ФЕНИЛЭТИЛИДЕН)-1-(3-ЭТОКСИКАРБОНИЛ)-4,5,6-7-ТЕТРАГИДРОБЕНЗО[b]ТИОФЕН-2-ИЛ)4,5-ДИГИДРО-1Н-ПИРРОЛ-3-КАРБОНОВОЙ КИСЛОТЫ, ОБЛАДАЮЩИЙ ПРОТИВОМИКРОБНОЙ АКТИВНОСТЬЮ
|
|
US20230212131A1
(en)
*
|
2020-06-09 |
2023-07-06 |
Anima Biotech Inc. |
Collagen 1 translation inhibitors and methods of use thereof
|
|
US20240239746A1
(en)
|
2021-04-26 |
2024-07-18 |
Sunshine Lake Pharma Co., Ltd. |
Preparation method for pyrrole amide compound
|
|
CN114456098B
(zh)
*
|
2022-01-19 |
2024-06-14 |
大连理工大学 |
糖尿病肾病药物艾莎利酮的制备方法
|