HUE037007T2 - Eljárás pirrol származék elõállítására és annak intermediere - Google Patents
Eljárás pirrol származék elõállítására és annak intermediereInfo
- Publication number
- HUE037007T2 HUE037007T2 HUE14839943A HUE14839943A HUE037007T2 HU E037007 T2 HUE037007 T2 HU E037007T2 HU E14839943 A HUE14839943 A HU E14839943A HU E14839943 A HUE14839943 A HU E14839943A HU E037007 T2 HUE037007 T2 HU E037007T2
- Authority
- HU
- Hungary
- Prior art keywords
- pyrrole derivative
- producing pyrrole
- producing
- derivative
- pyrrole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/456—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013175172 | 2013-08-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE037007T2 true HUE037007T2 (hu) | 2018-08-28 |
Family
ID=52586564
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE14839943A HUE037007T2 (hu) | 2013-08-27 | 2014-08-26 | Eljárás pirrol származék elõállítására és annak intermediere |
Country Status (10)
Country | Link |
---|---|
US (3) | US9765025B2 (hu) |
EP (1) | EP3040330B1 (hu) |
JP (1) | JP6422871B2 (hu) |
KR (1) | KR102226982B1 (hu) |
CN (1) | CN105473552B (hu) |
CA (1) | CA2922350C (hu) |
ES (1) | ES2660988T3 (hu) |
HU (1) | HUE037007T2 (hu) |
TW (1) | TWI635076B (hu) |
WO (1) | WO2015030010A1 (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201706806D0 (en) | 2017-04-28 | 2017-06-14 | Sentinel Oncology Ltd | Pharmaceutical compounds |
CN115246785B (zh) * | 2021-04-26 | 2024-03-26 | 年衍药业(珠海)有限公司 | 吡咯酰胺化合物的制备方法 |
CN115784961A (zh) * | 2021-09-10 | 2023-03-14 | 上海鼎雅药物化学科技有限公司 | 埃沙西林酮及其中间体的合成方法 |
WO2023134677A1 (zh) * | 2022-01-14 | 2023-07-20 | 广东东阳光药业有限公司 | 制备吡咯化合物的方法及其中间体 |
CN114456098B (zh) * | 2022-01-19 | 2024-06-14 | 大连理工大学 | 糖尿病肾病药物艾莎利酮的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1773768T3 (pl) | 2004-07-30 | 2019-03-29 | Exelixis, Inc. | Pochodne pirolu jako środki farmaceutyczne |
CN101006052B (zh) * | 2004-07-30 | 2013-11-06 | 埃克塞利希斯股份有限公司 | 作为药用制剂的吡咯衍生物 |
TWI444185B (zh) | 2007-04-09 | 2014-07-11 | Daiichi Sankyo Co Ltd | 吡咯衍生物之阻轉異構物 |
JP2010111657A (ja) * | 2008-10-07 | 2010-05-20 | Daiichi Sankyo Co Ltd | ピロール誘導体のアトロプ異性体を含有する医薬 |
JP5767586B2 (ja) | 2008-10-08 | 2015-08-19 | エグゼリクシス, インコーポレイテッド | (ヒドロキシアルキル)ピロール誘導体のアトロプ異性体 |
WO2010098286A1 (ja) * | 2009-02-25 | 2010-09-02 | 第一三共株式会社 | ミネラルコルチコイド受容体拮抗薬を含有する医薬 |
EP3190102B1 (en) * | 2013-04-10 | 2018-09-12 | Daiichi Sankyo Company, Limited | CRYSTAL OF (S)-1-(2-HYDROXYETHYL)-4-METHYL-N- [4-(METHYLSULFONYL)PHENYL]-5-[2-(TRIFLUOROMETHYL)& xA;PHENYL]- 1H-PYRROLE-3-CARBOXAMIDE |
-
2014
- 2014-08-26 HU HUE14839943A patent/HUE037007T2/hu unknown
- 2014-08-26 EP EP14839943.9A patent/EP3040330B1/en active Active
- 2014-08-26 JP JP2015534240A patent/JP6422871B2/ja active Active
- 2014-08-26 CA CA2922350A patent/CA2922350C/en active Active
- 2014-08-26 KR KR1020167004705A patent/KR102226982B1/ko active IP Right Grant
- 2014-08-26 CN CN201480047376.6A patent/CN105473552B/zh active Active
- 2014-08-26 WO PCT/JP2014/072332 patent/WO2015030010A1/ja active Application Filing
- 2014-08-26 ES ES14839943.9T patent/ES2660988T3/es active Active
- 2014-08-27 TW TW103129454A patent/TWI635076B/zh active
-
2016
- 2016-02-12 US US15/043,260 patent/US9765025B2/en active Active
-
2017
- 2017-09-08 US US15/699,954 patent/US10005725B2/en active Active
-
2018
- 2018-04-11 US US15/950,973 patent/US10308604B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN105473552A (zh) | 2016-04-06 |
TW201542522A (zh) | 2015-11-16 |
US20170369438A1 (en) | 2017-12-28 |
EP3040330B1 (en) | 2018-01-10 |
KR102226982B1 (ko) | 2021-03-11 |
EP3040330A4 (en) | 2017-04-19 |
TWI635076B (zh) | 2018-09-11 |
KR20160045724A (ko) | 2016-04-27 |
US10308604B2 (en) | 2019-06-04 |
WO2015030010A1 (ja) | 2015-03-05 |
US9765025B2 (en) | 2017-09-19 |
US20160237034A1 (en) | 2016-08-18 |
CA2922350C (en) | 2018-04-17 |
CA2922350A1 (en) | 2015-03-05 |
ES2660988T3 (es) | 2018-03-27 |
US10005725B2 (en) | 2018-06-26 |
EP3040330A1 (en) | 2016-07-06 |
CN105473552B (zh) | 2017-11-10 |
US20180230095A1 (en) | 2018-08-16 |
JPWO2015030010A1 (ja) | 2017-03-02 |
JP6422871B2 (ja) | 2018-11-14 |
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