JP2008504335A5 - - Google Patents
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- Publication number
- JP2008504335A5 JP2008504335A5 JP2007518555A JP2007518555A JP2008504335A5 JP 2008504335 A5 JP2008504335 A5 JP 2008504335A5 JP 2007518555 A JP2007518555 A JP 2007518555A JP 2007518555 A JP2007518555 A JP 2007518555A JP 2008504335 A5 JP2008504335 A5 JP 2008504335A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- double
- building blocks
- molecule
- nucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58467804P | 2004-07-02 | 2004-07-02 | |
| US64658605P | 2005-01-26 | 2005-01-26 | |
| PCT/EP2005/007198 WO2006002971A2 (en) | 2004-07-02 | 2005-07-04 | Nucleic acids for the treatment of hmgb1-related pathologies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008504335A JP2008504335A (ja) | 2008-02-14 |
| JP2008504335A5 true JP2008504335A5 (enExample) | 2008-08-21 |
Family
ID=35106975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007518555A Pending JP2008504335A (ja) | 2004-07-02 | 2005-07-04 | Ｈｍｇｂ１に関連する病変の治療のための核酸 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080305073A1 (enExample) |
| EP (1) | EP1768677B1 (enExample) |
| JP (1) | JP2008504335A (enExample) |
| AT (1) | ATE399014T1 (enExample) |
| AU (1) | AU2005259381A1 (enExample) |
| BR (1) | BRPI0512944A (enExample) |
| CA (1) | CA2572519A1 (enExample) |
| DE (1) | DE602005007746D1 (enExample) |
| DK (1) | DK1768677T3 (enExample) |
| ES (1) | ES2306195T3 (enExample) |
| IL (1) | IL179828A0 (enExample) |
| PL (1) | PL1768677T3 (enExample) |
| PT (1) | PT1768677E (enExample) |
| WO (1) | WO2006002971A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GEP20105110B (en) | 2004-08-03 | 2010-11-10 | Transtech Pharma Inc | Rage fusion proteins and their use |
| US20100172909A1 (en) * | 2005-10-24 | 2010-07-08 | Masahiro Nishibori | Cerebral edema suppressant |
| EP1989227A2 (en) * | 2006-02-09 | 2008-11-12 | Transtech Pharma, Inc. | Rage fusion proteins and methods of use |
| JP3882090B1 (ja) * | 2006-05-19 | 2007-02-14 | 国立大学法人 岡山大学 | 脳血管攣縮抑制剤 |
| KR20090087483A (ko) * | 2006-11-17 | 2009-08-17 | 클리니컬 진 네트웍스 아베 | 유전자 ｇｙｐｃ, ａｇｐａｔ3, ａｇｌ, ｐｖｒｌ2, ｈｍｇｂ3, ｈｓｄｌ2 및/또는 ｌｄｂ2를 포함하는 스크리닝 및 치료방법 |
| CN101589309A (zh) * | 2006-11-17 | 2009-11-25 | 临床基因网络公司 | 涉及基因gypc、agpat3、agl、pvrl2、hmgb3、hsdl2和/或ldb2的筛选和治疗方法 |
| US8927510B2 (en) | 2008-05-16 | 2015-01-06 | Children's Medical Center Corporation | Compositions and methods for inhibition of retroviruses |
| WO2009149921A2 (en) * | 2008-06-11 | 2009-12-17 | Bionucleon S.R.L. | Inhibition of hrp-3 using modified oligonucleotides |
| PT2329266E (pt) | 2008-09-11 | 2016-06-07 | Pasteur Institut | Monitorização e inibição da infecção pelo vírus da imunodeficiência humana mediante modulação do desencadeamento dependente de hmgb1 da replicação e persistência do vih-1 |
| US20120165244A1 (en) * | 2008-10-30 | 2012-06-28 | Hua-Lin Wu | Methods for binding lewis y antigen |
| NZ593438A (en) | 2008-12-22 | 2012-12-21 | Creabilis S A | Synthesis of polymer conjugates of indolocarbazole compounds |
| AU2010240569A1 (en) | 2009-04-20 | 2011-10-20 | Pfizer Inc. | Control of protein glycosylation and compositions and methods relating thereto |
| GB0911569D0 (en) * | 2009-07-03 | 2009-08-12 | Ulive Entpr Ltd | Method for the detection of organ or tissue injury |
| JP5467313B2 (ja) * | 2009-09-28 | 2014-04-09 | 国立大学法人 岡山大学 | アテローム動脈硬化抑制剤 |
| US8975019B2 (en) * | 2009-10-19 | 2015-03-10 | University Of Massachusetts | Deducing exon connectivity by RNA-templated DNA ligation/sequencing |
| JP5686814B2 (ja) * | 2010-09-17 | 2015-03-18 | 独立行政法人科学技術振興機構 | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| US20140378531A1 (en) * | 2012-02-01 | 2014-12-25 | New York University | Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors |
| JP6624542B2 (ja) * | 2015-02-05 | 2019-12-25 | 国立大学法人広島大学 | ヒトｈｍｇｂ１結合剤およびヒトｈｍｇｂ１除去装置 |
| WO2018175340A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Reduced exposure conjugates modulating therapeutic targets |
| WO2018175315A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates of staurosporine derivatives having reduced exposure |
| WO2018175302A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates targeting c-src with reduced exposure |
| WO2018175301A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugate of montesanib with reduced exposure |
| WO2018208369A1 (en) | 2017-05-10 | 2018-11-15 | Sienna Biopharmaceuticals, Inc. | Uses of polymer conjugates of indolocarbazole compounds with reduced exposure |
| CN111304202B (zh) * | 2020-02-26 | 2023-03-28 | 西安交通大学 | 一种用于识别且增强hmgb1生物学活性的核酸适配子及其应用 |
| CN114957440A (zh) * | 2022-05-26 | 2022-08-30 | 江苏大学 | 一种重组HMGB1 A Box蛋白及其获取方法与应用 |
| CN119630405A (zh) * | 2022-06-23 | 2025-03-14 | J·大卫格莱斯顿研究所-根据J·大卫格莱斯顿遗嘱的遗嘱信托 | 用于治疗包括阿尔茨海默病的APOE4相关Tau蛋白病的HMGB1抑制剂 |
| CN114807150B (zh) * | 2022-06-28 | 2022-10-14 | 中国科学院基础医学与肿瘤研究所(筹) | 靶向和拮抗hmgb1分子的核酸适体 |
| CA3262218A1 (en) | 2022-07-19 | 2024-01-25 | Rampart Bioscience, Inc. | CIRCULAR NON-IMMUNOGENEOUS NON-VIRAL DNA VECTORS |
| CN115774004B (zh) * | 2022-08-19 | 2024-07-05 | 四川大学华西医院 | 二氧化锆@量子点复合微球在制备检测hmgb1的荧光探针中的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5442194A (en) * | 1992-10-14 | 1994-05-09 | University Research Corporation | Method for selecting nucleic acids on the basis of structure |
| US7754217B2 (en) * | 2001-03-16 | 2010-07-13 | Bio3 Research Srl | HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
| JP2006510619A (ja) * | 2002-11-20 | 2006-03-30 | クリティカル セラピューティクス，インコーポレイテッド | 抗炎症剤としてのｈｍｇｂ断片の使用 |
-
2005
- 2005-07-04 EP EP05773148A patent/EP1768677B1/en not_active Revoked
- 2005-07-04 WO PCT/EP2005/007198 patent/WO2006002971A2/en not_active Ceased
- 2005-07-04 PT PT05773148T patent/PT1768677E/pt unknown
- 2005-07-04 ES ES05773148T patent/ES2306195T3/es not_active Expired - Lifetime
- 2005-07-04 JP JP2007518555A patent/JP2008504335A/ja active Pending
- 2005-07-04 PL PL05773148T patent/PL1768677T3/pl unknown
- 2005-07-04 DE DE602005007746T patent/DE602005007746D1/de not_active Revoked
- 2005-07-04 AU AU2005259381A patent/AU2005259381A1/en not_active Abandoned
- 2005-07-04 BR BRPI0512944-3A patent/BRPI0512944A/pt not_active IP Right Cessation
- 2005-07-04 US US11/631,328 patent/US20080305073A1/en not_active Abandoned
- 2005-07-04 DK DK05773148T patent/DK1768677T3/da active
- 2005-07-04 AT AT05773148T patent/ATE399014T1/de not_active IP Right Cessation
- 2005-07-04 CA CA002572519A patent/CA2572519A1/en not_active Abandoned
-
2006
- 2006-12-04 IL IL179828A patent/IL179828A0/en unknown
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