JP2008504335A - Ｈｍｇｂ１に関連する病変の治療のための核酸 - Google Patents
Ｈｍｇｂ１に関連する病変の治療のための核酸 Download PDFInfo
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| PCT/EP2005/007198 WO2006002971A2 (en) | 2004-07-02 | 2005-07-04 | Nucleic acids for the treatment of hmgb1-related pathologies |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012036215A1 (ja) | 2010-09-17 | 2012-03-22 | Taniguchi Tadatsugu | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| JP2012532310A (ja) * | 2009-07-03 | 2012-12-13 | ザ・ユニヴァーシティ・オヴ・リヴァプール | 器官または組織の損傷を検出する方法 |
| JP2016141678A (ja) * | 2015-02-05 | 2016-08-08 | 国立大学法人広島大学 | ヒトｈｍｇｂ１結合剤、ヒトｈｍｇｂ１除去装置および新規ポリペプチド |
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| KR101323411B1 (ko) | 2004-08-03 | 2013-10-30 | 트랜스테크 파르마, 인크. | Ｒａｇｅ 융합 단백질 및 이의 사용 방법 |
| US20100172909A1 (en) * | 2005-10-24 | 2010-07-08 | Masahiro Nishibori | Cerebral edema suppressant |
| EP1989227A2 (en) * | 2006-02-09 | 2008-11-12 | Transtech Pharma, Inc. | Rage fusion proteins and methods of use |
| JP3882090B1 (ja) * | 2006-05-19 | 2007-02-14 | 国立大学法人 岡山大学 | 脳血管攣縮抑制剤 |
| KR20090087483A (ko) * | 2006-11-17 | 2009-08-17 | 클리니컬 진 네트웍스 아베 | 유전자 ｇｙｐｃ, ａｇｐａｔ3, ａｇｌ, ｐｖｒｌ2, ｈｍｇｂ3, ｈｓｄｌ2 및/또는 ｌｄｂ2를 포함하는 스크리닝 및 치료방법 |
| CN101589309A (zh) * | 2006-11-17 | 2009-11-25 | 临床基因网络公司 | 涉及基因gypc、agpat3、agl、pvrl2、hmgb3、hsdl2和/或ldb2的筛选和治疗方法 |
| WO2009140676A2 (en) * | 2008-05-16 | 2009-11-19 | Immune Disease Institute, Inc. | Compositions and methods for inhibition of retroviruses |
| US8710021B2 (en) | 2008-06-11 | 2014-04-29 | Bionucleon S.R.L. | Inhibition of HRP-3 using modified oligonucleotides |
| BRPI0916349A2 (pt) | 2008-09-11 | 2019-09-24 | Pasteur Institut | monitoramento e inibição da infecção pelo vírus da imunodeficiência humana através da modulação do desencadeamento dependete de hmgb1 da replicação e persistência do hiv-1 |
| US20120165244A1 (en) * | 2008-10-30 | 2012-06-28 | Hua-Lin Wu | Methods for binding lewis y antigen |
| KR101431165B1 (ko) | 2008-12-22 | 2014-08-18 | 크레아빌리스 에스.에이. | 인돌로카르바졸 화합물의 중합체 컨쥬케이트의 합성 |
| RU2011142230A (ru) | 2009-04-20 | 2013-05-27 | Пфайзер Инк. | Контроль гликозилирования белка и композиции и способы, касающиеся этого |
| JP5467313B2 (ja) * | 2009-09-28 | 2014-04-09 | 国立大学法人 岡山大学 | アテローム動脈硬化抑制剤 |
| US8975019B2 (en) * | 2009-10-19 | 2015-03-10 | University Of Massachusetts | Deducing exon connectivity by RNA-templated DNA ligation/sequencing |
| WO2013116590A1 (en) * | 2012-02-01 | 2013-08-08 | George Miller | Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors |
| WO2018175301A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugate of montesanib with reduced exposure |
| WO2018175315A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates of staurosporine derivatives having reduced exposure |
| WO2018175302A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates targeting c-src with reduced exposure |
| EP3600440A1 (en) | 2017-03-20 | 2020-02-05 | Sienna Biopharmaceuticals, Inc. | Reduced exposure conjugates modulating therapeutic targets |
| EP3621657A1 (en) | 2017-05-10 | 2020-03-18 | Sienna Biopharmaceuticals, Inc. | Uses of polymer conjugates of indolocarbazole compounds with reduced exposure |
| CN111304202B (zh) * | 2020-02-26 | 2023-03-28 | 西安交通大学 | 一种用于识别且增强hmgb1生物学活性的核酸适配子及其应用 |
| CN114957440A (zh) * | 2022-05-26 | 2022-08-30 | 江苏大学 | 一种重组HMGB1 A Box蛋白及其获取方法与应用 |
| US20250262230A1 (en) * | 2022-06-23 | 2025-08-21 | The Regents Of The University Of California | HMGB1 Inhibitors for Treatment of APOE4-related Tauopathies including Alzheimer’s Disease |
| CN114807150B (zh) * | 2022-06-28 | 2022-10-14 | 中国科学院基础医学与肿瘤研究所(筹) | 靶向和拮抗hmgb1分子的核酸适体 |
| JP2025525583A (ja) | 2022-07-19 | 2025-08-05 | ランパート バイオサイエンス インコーポレイテッド | 非免疫原性環状非ウイルス性ｄｎａベクター |
| CN115774004B (zh) * | 2022-08-19 | 2024-07-05 | 四川大学华西医院 | 二氧化锆@量子点复合微球在制备检测hmgb1的荧光探针中的用途 |
Citations (1)
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| WO2002074337A1 (en) * | 2001-03-16 | 2002-09-26 | Bio3 Research S.R.L. | Hmgb1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
Family Cites Families (2)
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|---|---|---|---|---|
| AU5442194A (en) * | 1992-10-14 | 1994-05-09 | University Research Corporation | Method for selecting nucleic acids on the basis of structure |
| NZ540067A (en) * | 2002-11-20 | 2007-05-31 | Critical Therapeutics Inc | A purified preparation of antibodies that specifically bind to a high mobility group box protein (HMGB) B box but do not specifically to non-B box epitopes of HMGB |
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2005
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- 2005-07-04 DK DK05773148T patent/DK1768677T3/da active
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- 2005-07-04 WO PCT/EP2005/007198 patent/WO2006002971A2/en not_active Ceased
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- 2005-07-04 AT AT05773148T patent/ATE399014T1/de not_active IP Right Cessation
- 2005-07-04 AU AU2005259381A patent/AU2005259381A1/en not_active Abandoned
- 2005-07-04 BR BRPI0512944-3A patent/BRPI0512944A/pt not_active IP Right Cessation
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002074337A1 (en) * | 2001-03-16 | 2002-09-26 | Bio3 Research S.R.L. | Hmgb1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012532310A (ja) * | 2009-07-03 | 2012-12-13 | ザ・ユニヴァーシティ・オヴ・リヴァプール | 器官または組織の損傷を検出する方法 |
| WO2012036215A1 (ja) | 2010-09-17 | 2012-03-22 | Taniguchi Tadatsugu | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| US9186371B2 (en) | 2010-09-17 | 2015-11-17 | Japan Science And Technology Agency | Inhibitor of HMGB protein-mediated immune response activation, and screening method |
| JP2016141678A (ja) * | 2015-02-05 | 2016-08-08 | 国立大学法人広島大学 | ヒトｈｍｇｂ１結合剤、ヒトｈｍｇｂ１除去装置および新規ポリペプチド |
Also Published As
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| PL1768677T3 (pl) | 2009-01-30 |
| ATE399014T1 (de) | 2008-07-15 |
| CA2572519A1 (en) | 2006-01-12 |
| BRPI0512944A (pt) | 2008-04-15 |
| WO2006002971A3 (en) | 2006-04-20 |
| AU2005259381A1 (en) | 2006-01-12 |
| WO2006002971A2 (en) | 2006-01-12 |
| DE602005007746D1 (de) | 2008-08-07 |
| US20080305073A1 (en) | 2008-12-11 |
| EP1768677B1 (en) | 2008-06-25 |
| EP1768677A2 (en) | 2007-04-04 |
| DK1768677T3 (da) | 2008-10-20 |
| ES2306195T3 (es) | 2008-11-01 |
| IL179828A0 (en) | 2008-03-20 |
| PT1768677E (pt) | 2008-10-06 |
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