JP2008504335A - Ｈｍｇｂ１に関連する病変の治療のための核酸 - Google Patents
Ｈｍｇｂ１に関連する病変の治療のための核酸 Download PDFInfo
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| US58467804P | 2004-07-02 | 2004-07-02 | |
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| PCT/EP2005/007198 WO2006002971A2 (en) | 2004-07-02 | 2005-07-04 | Nucleic acids for the treatment of hmgb1-related pathologies |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012036215A1 (ja) | 2010-09-17 | 2012-03-22 | Taniguchi Tadatsugu | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| JP2012532310A (ja) * | 2009-07-03 | 2012-12-13 | ザ・ユニヴァーシティ・オヴ・リヴァプール | 器官または組織の損傷を検出する方法 |
| JP2016141678A (ja) * | 2015-02-05 | 2016-08-08 | 国立大学法人広島大学 | ヒトｈｍｇｂ１結合剤、ヒトｈｍｇｂ１除去装置および新規ポリペプチド |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007001559A (es) | 2004-08-03 | 2007-04-10 | Transtech Pharma Inc | Proteinas de fusion de receptor para productos finales glicados avanzados y metodos de uso. |
| US20100172909A1 (en) * | 2005-10-24 | 2010-07-08 | Masahiro Nishibori | Cerebral edema suppressant |
| CN101410411A (zh) * | 2006-02-09 | 2009-04-15 | 转化技术制药公司 | Rage融合蛋白及使用方法 |
| JP3882090B1 (ja) * | 2006-05-19 | 2007-02-14 | 国立大学法人 岡山大学 | 脳血管攣縮抑制剤 |
| KR20090087483A (ko) * | 2006-11-17 | 2009-08-17 | 클리니컬 진 네트웍스 아베 | 유전자 ｇｙｐｃ, ａｇｐａｔ3, ａｇｌ, ｐｖｒｌ2, ｈｍｇｂ3, ｈｓｄｌ2 및/또는 ｌｄｂ2를 포함하는 스크리닝 및 치료방법 |
| CN101589309A (zh) * | 2006-11-17 | 2009-11-25 | 临床基因网络公司 | 涉及基因gypc、agpat3、agl、pvrl2、hmgb3、hsdl2和/或ldb2的筛选和治疗方法 |
| WO2009140676A2 (en) * | 2008-05-16 | 2009-11-19 | Immune Disease Institute, Inc. | Compositions and methods for inhibition of retroviruses |
| US8710021B2 (en) | 2008-06-11 | 2014-04-29 | Bionucleon S.R.L. | Inhibition of HRP-3 using modified oligonucleotides |
| JP5710482B2 (ja) | 2008-09-11 | 2015-04-30 | アンスティテュ・パストゥール | Ｈｍｇｂ１依存型誘発のｈｉｖ−１複製および持続の調節によるヒト免疫不全ウイルス感染の監視および阻害 |
| US20120165244A1 (en) * | 2008-10-30 | 2012-06-28 | Hua-Lin Wu | Methods for binding lewis y antigen |
| BRPI0923583A2 (pt) | 2008-12-22 | 2018-10-09 | Creabilis S A | síntese de conjugados de polímeros de compostos de indocarbzol. |
| EP2421892A1 (en) | 2009-04-20 | 2012-02-29 | Pfizer Inc. | Control of protein glycosylation and compositions and methods relating thereto |
| JP5467313B2 (ja) * | 2009-09-28 | 2014-04-09 | 国立大学法人 岡山大学 | アテローム動脈硬化抑制剤 |
| US8975019B2 (en) * | 2009-10-19 | 2015-03-10 | University Of Massachusetts | Deducing exon connectivity by RNA-templated DNA ligation/sequencing |
| WO2013116590A1 (en) * | 2012-02-01 | 2013-08-08 | George Miller | Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors |
| WO2018175340A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Reduced exposure conjugates modulating therapeutic targets |
| WO2018175315A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates of staurosporine derivatives having reduced exposure |
| WO2018175302A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates targeting c-src with reduced exposure |
| WO2018175301A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugate of montesanib with reduced exposure |
| WO2018208369A1 (en) | 2017-05-10 | 2018-11-15 | Sienna Biopharmaceuticals, Inc. | Uses of polymer conjugates of indolocarbazole compounds with reduced exposure |
| CN111304202B (zh) * | 2020-02-26 | 2023-03-28 | 西安交通大学 | 一种用于识别且增强hmgb1生物学活性的核酸适配子及其应用 |
| CN114957440A (zh) * | 2022-05-26 | 2022-08-30 | 江苏大学 | 一种重组HMGB1 A Box蛋白及其获取方法与应用 |
| JP2025521607A (ja) * | 2022-06-23 | 2025-07-10 | ザ ジェイ． デビッド グラッドストーン インスティテューツ、 ア テスタメンタリー トラスト エスタブリッシュド アンダー ザ ウィル オブ ジェイ． デビッド グラッドストーン | アルツハイマー病を含むａｐｏｅ４－関連タウオパチーの治療のためのｈｍｇｂ１阻害剤 |
| CN114807150B (zh) * | 2022-06-28 | 2022-10-14 | 中国科学院基础医学与肿瘤研究所(筹) | 靶向和拮抗hmgb1分子的核酸适体 |
| WO2024020320A2 (en) | 2022-07-19 | 2024-01-25 | Rampart Bioscience, Inc. | Non-immunogenic circular, non-viral dna vectors |
| CN115774004B (zh) * | 2022-08-19 | 2024-07-05 | 四川大学华西医院 | 二氧化锆@量子点复合微球在制备检测hmgb1的荧光探针中的用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002074337A1 (en) * | 2001-03-16 | 2002-09-26 | Bio3 Research S.R.L. | Hmgb1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994009158A1 (en) * | 1992-10-14 | 1994-04-28 | University Research Corporation | Method for selecting nucleic acids on the basis of structure |
| NZ540067A (en) * | 2002-11-20 | 2007-05-31 | Critical Therapeutics Inc | A purified preparation of antibodies that specifically bind to a high mobility group box protein (HMGB) B box but do not specifically to non-B box epitopes of HMGB |
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2005
- 2005-07-04 PT PT05773148T patent/PT1768677E/pt unknown
- 2005-07-04 WO PCT/EP2005/007198 patent/WO2006002971A2/en not_active Ceased
- 2005-07-04 CA CA002572519A patent/CA2572519A1/en not_active Abandoned
- 2005-07-04 ES ES05773148T patent/ES2306195T3/es not_active Expired - Lifetime
- 2005-07-04 DE DE602005007746T patent/DE602005007746D1/de not_active Revoked
- 2005-07-04 AU AU2005259381A patent/AU2005259381A1/en not_active Abandoned
- 2005-07-04 BR BRPI0512944-3A patent/BRPI0512944A/pt not_active IP Right Cessation
- 2005-07-04 EP EP05773148A patent/EP1768677B1/en not_active Revoked
- 2005-07-04 US US11/631,328 patent/US20080305073A1/en not_active Abandoned
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- 2005-07-04 PL PL05773148T patent/PL1768677T3/pl unknown
- 2005-07-04 JP JP2007518555A patent/JP2008504335A/ja active Pending
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002074337A1 (en) * | 2001-03-16 | 2002-09-26 | Bio3 Research S.R.L. | Hmgb1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012532310A (ja) * | 2009-07-03 | 2012-12-13 | ザ・ユニヴァーシティ・オヴ・リヴァプール | 器官または組織の損傷を検出する方法 |
| WO2012036215A1 (ja) | 2010-09-17 | 2012-03-22 | Taniguchi Tadatsugu | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| US9186371B2 (en) | 2010-09-17 | 2015-11-17 | Japan Science And Technology Agency | Inhibitor of HMGB protein-mediated immune response activation, and screening method |
| JP2016141678A (ja) * | 2015-02-05 | 2016-08-08 | 国立大学法人広島大学 | ヒトｈｍｇｂ１結合剤、ヒトｈｍｇｂ１除去装置および新規ポリペプチド |
Also Published As
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| WO2006002971A3 (en) | 2006-04-20 |
| CA2572519A1 (en) | 2006-01-12 |
| BRPI0512944A (pt) | 2008-04-15 |
| AU2005259381A1 (en) | 2006-01-12 |
| ES2306195T3 (es) | 2008-11-01 |
| EP1768677B1 (en) | 2008-06-25 |
| DE602005007746D1 (de) | 2008-08-07 |
| IL179828A0 (en) | 2008-03-20 |
| PL1768677T3 (pl) | 2009-01-30 |
| EP1768677A2 (en) | 2007-04-04 |
| DK1768677T3 (da) | 2008-10-20 |
| WO2006002971A2 (en) | 2006-01-12 |
| ATE399014T1 (de) | 2008-07-15 |
| PT1768677E (pt) | 2008-10-06 |
| US20080305073A1 (en) | 2008-12-11 |
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