|
BE567431A
(OSRAM)
|
1957-05-07 |
|
|
|
|
US4323581A
(en)
|
1978-07-31 |
1982-04-06 |
Johnson & Johnson |
Method of treating carcinogenesis
|
|
IE52670B1
(en)
|
1981-03-03 |
1988-01-20 |
Leo Ab |
Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
US4806352A
(en)
|
1986-04-15 |
1989-02-21 |
Ribi Immunochem Research Inc. |
Immunological lipid emulsion adjuvant
|
|
EP0273512B1
(en)
|
1986-12-19 |
1991-02-27 |
Duphar International Research B.V |
Stabilised adjuvant suspension comprising dimethyl dioctadecyl ammonium bromide
|
|
US4923986A
(en)
|
1987-03-09 |
1990-05-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Derivatives of physiologically active substance K-252
|
|
DE3875762T2
(de)
|
1987-03-17 |
1993-05-13 |
Akzo Nv |
Adjuvanzienmischung.
|
|
WO1989007105A1
(fr)
|
1988-02-04 |
1989-08-10 |
Kyowa Hakko Kogyo Co., Ltd. |
Derives de staurosporine
|
|
IL89167A
(en)
|
1988-02-10 |
1994-02-27 |
Hoffmann La Roche |
Substituted pyrroles, their manufacture and pharmaceutical compositions containing them
|
|
DE3841091A1
(de)
|
1988-12-07 |
1990-06-13 |
Behringwerke Ag |
Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
ES2055785T3
(es)
|
1989-01-17 |
1994-09-01 |
Eniricerche Spa |
Peptidos sinteticos y su uso como vehiculos universales para la preparacion de conjugados inmunogenos aptos para el desarrollo de vacunas sinteticas.
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
CA2011896C
(en)
|
1989-04-21 |
2001-05-08 |
Mark Werner |
Ringworm vaccine
|
|
ATE155813T1
(de)
|
1989-05-19 |
1997-08-15 |
Genentech Inc |
Her2 extrazellulare domäne
|
|
CA2017507C
(en)
|
1989-05-25 |
1996-11-12 |
Gary Van Nest |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
JP3859695B2
(ja)
|
1989-08-04 |
2006-12-20 |
バーレックス ラボラトリーズ インコーポレイテッド |
Ｃ―ｅｒｂＢ―２外部ドメイン：ＧＰ７５
|
|
US5439936A
(en)
|
1989-10-03 |
1995-08-08 |
The Regents Of The University Of California |
Method of treating certain tumors using illudin analogs
|
|
IT1237764B
(it)
|
1989-11-10 |
1993-06-17 |
Eniricerche Spa |
Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
|
|
DE69113564T2
(de)
|
1990-08-13 |
1996-05-30 |
American Cyanamid Co |
Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
|
|
US5153312A
(en)
|
1990-09-28 |
1992-10-06 |
American Cyanamid Company |
Oligosaccharide conjugate vaccines
|
|
US5284652A
(en)
|
1990-10-26 |
1994-02-08 |
Pier Allan C |
Dermatophyte vaccine
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
WO1993007153A1
(en)
|
1991-10-10 |
1993-04-15 |
Schering Corporation |
4'-(n-substituted-n-oxide)staurosporine derivatives
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
JPH07505124A
(ja)
|
1991-11-08 |
1995-06-08 |
ザ ユニバーシティ オブ サザン カリフォルニア |
ニューロトロフィン活性増強のためのｋ−２５２化合物を含む組成物
|
|
AU671971B2
(en)
|
1991-11-29 |
1996-09-19 |
Chiron Corporation |
Anti-cancer immunotherapeutic vector constructs
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
AU3630093A
(en)
|
1992-03-02 |
1993-10-05 |
Biocine S.P.A. |
Helicobacter pylori proteins useful for vaccines and diagnostics
|
|
IT1262896B
(it)
|
1992-03-06 |
1996-07-22 |
|
Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
|
|
US5621100A
(en)
|
1992-07-24 |
1997-04-15 |
Cephalon, Inc. |
K-252a derivatives for treatment of neurological disorders
|
|
US5756494A
(en)
|
1992-07-24 |
1998-05-26 |
Cephalon, Inc. |
Protein kinase inhibitors for treatment of neurological disorders
|
|
US5674867A
(en)
|
1992-09-21 |
1997-10-07 |
Kyowa Hakko Kogyo Co., Ltd. |
Indolocarbazole derivatives and therapeutic method for stimulating megakaicyocyte production
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
ATE195735T1
(de)
|
1993-07-15 |
2000-09-15 |
Minnesota Mining & Mfg |
Imidazo (4,5-c)pyridin-4-amine
|
|
US5624949A
(en)
|
1993-12-07 |
1997-04-29 |
Eli Lilly And Company |
Protein kinase C inhibitors
|
|
JP3998261B2
(ja)
|
1993-12-23 |
2007-10-24 |
イーライ・リリー・アンド・カンパニー |
プロテインキナーゼｃ阻害剤
|
|
US6083903A
(en)
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
CA2216796C
(en)
|
1995-03-30 |
2003-09-02 |
Pfizer Inc. |
Quinazoline derivatives
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US6331555B1
(en)
|
1995-06-01 |
2001-12-18 |
University Of California |
Treatment of platelet derived growth factor related disorders such as cancers
|
|
US5747498A
(en)
*
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
GB9513261D0
(en)
|
1995-06-29 |
1995-09-06 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5554519A
(en)
|
1995-08-07 |
1996-09-10 |
Fermalogic, Inc. |
Process of preparing genistein
|
|
WO1997007081A2
(en)
|
1995-08-11 |
1997-02-27 |
Yale University |
Glycosylated indolocarbazole synthesis
|
|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
ATE321757T1
(de)
|
1995-12-08 |
2006-04-15 |
Janssen Pharmaceutica Nv |
(imidazol-5-yl)methyl-2-chinolinonderivate als farnesyl protein transferase inhibitoren
|
|
JP2000511769A
(ja)
|
1996-04-02 |
2000-09-12 |
スミスクライン・ビーチャム・コーポレイション |
新規化合物
|
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
|
JP2000512487A
(ja)
|
1996-05-14 |
2000-09-26 |
スミスクライン・ビーチャム・コーポレイション |
新規化合物
|
|
KR100447918B1
(ko)
|
1996-07-25 |
2005-09-28 |
동아제약주식회사 |
대장을포함한위장관보호작용을갖는플라본및플라바논화합물
|
|
DE19630390A1
(de)
|
1996-07-26 |
1998-01-29 |
Chiron Behring Gmbh & Co |
Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung
|
|
CA2639051A1
(en)
|
1996-09-04 |
1998-03-12 |
Takara Bio Inc. |
Fungal antigens and process for producing the same
|
|
US5908934A
(en)
|
1996-09-26 |
1999-06-01 |
Bristol-Myers Squibb Company |
Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs
|
|
US6610661B1
(en)
|
1996-10-11 |
2003-08-26 |
The Regents Of The University Of California |
Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
|
|
EP0942983B2
(en)
|
1996-10-31 |
2014-09-10 |
Human Genome Sciences, Inc. |
Streptococcus pneumoniae antigens and vaccines
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6299881B1
(en)
|
1997-03-24 |
2001-10-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
|
|
EP2085090A3
(en)
|
1997-06-06 |
2012-05-02 |
The Regents of the University of California |
Inhibitors of DNA immunostimulatory sequence activity
|
|
GB9712347D0
(en)
|
1997-06-14 |
1997-08-13 |
Smithkline Beecham Biolog |
Vaccine
|
|
GB9713156D0
(en)
|
1997-06-20 |
1997-08-27 |
Microbiological Res Authority |
Vaccines
|
|
US6800744B1
(en)
|
1997-07-02 |
2004-10-05 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
|
|
CA2294244A1
(en)
|
1997-07-12 |
1999-01-21 |
Cancer Research Campaign Technology Limited |
Cyclin dependent kinase inhibiting purine derivatives
|
|
US5948413A
(en)
|
1997-07-17 |
1999-09-07 |
Board Of Trustees Operating Michigan State University |
Method and vaccine for treatment of pythiosis insidiosi in humans and lower animals
|
|
DE69838992T2
(de)
|
1997-09-05 |
2008-12-24 |
Glaxosmithkline Biologicals S.A., Rixensart |
Öl-in-Wasser Emulsionen mit Saponinen
|
|
AU762606B2
(en)
|
1997-11-21 |
2003-06-26 |
Genset S.A. |
Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
|
|
WO1999028475A2
(en)
|
1997-11-28 |
1999-06-10 |
Genset |
Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
|
|
UA67760C2
(uk)
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
|
GB9800569D0
(en)
*
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
US6303114B1
(en)
|
1998-03-05 |
2001-10-16 |
The Medical College Of Ohio |
IL-12 enhancement of immune responses to T-independent antigens
|
|
GB9807721D0
(en)
|
1998-04-08 |
1998-06-10 |
Chiron Spa |
Antigen
|
|
WO1999052549A1
(en)
|
1998-04-09 |
1999-10-21 |
Smithkline Beecham Biologicals S.A. |
Adjuvant compositions
|
|
GB9810193D0
(en)
|
1998-05-12 |
1998-07-08 |
Smithkline Beecham Biolog |
Novel compounds
|
|
IL139934A
(en)
|
1998-05-29 |
2007-10-31 |
Sugen Inc |
History 2 - Indulinone converted to pyrrole and pharmaceutical preparations containing them
|
|
EP1032574B1
(en)
|
1998-09-30 |
2007-06-13 |
Walter Reed Army Institute of Research |
INDOLO 2,1-b|QUINAZOLE-6,12-DIONE ANTIMALARIAL COMPOUNDS AND METHODS OF TREATING MALARIA THEREWITH
|
|
AU1202200A
(en)
|
1998-10-09 |
2000-05-01 |
Chiron Corporation |
Neisseria genomic sequences and methods of their use
|
|
DK1126876T3
(da)
|
1998-10-16 |
2007-07-02 |
Glaxosmithkline Biolog Sa |
Adjuvanssystemer og vacciner
|
|
US20030083242A1
(en)
|
1998-11-06 |
2003-05-01 |
Alphonse Galdes |
Methods and compositions for treating or preventing peripheral neuropathies
|
|
AU1722300A
(en)
|
1998-11-12 |
2000-05-29 |
Regents Of The University Of California, The |
Chlamydia pneumoniae genome sequence
|
|
GB9828000D0
(en)
|
1998-12-18 |
1999-02-10 |
Chiron Spa |
Antigens
|
|
IL145043A0
(en)
|
1999-03-19 |
2002-06-30 |
Smithkline Beecham Biolog |
Vaccine
|
|
TR200103018T2
(tr)
|
1999-04-19 |
2002-02-21 |
Beecham Biologicals S.A. Smithkline |
İmmünostimülatör oligonükleotid ve saponin içeren katkı bileşikleri.
|
|
WO2000067161A2
(en)
|
1999-05-04 |
2000-11-09 |
Grant Lee H |
Method and apparatus for categorizing and retrieving network pages and sites
|
|
US6806266B1
(en)
|
1999-07-13 |
2004-10-19 |
Kyowa Hakko Kogyo Co., Ltd. |
Staurosporin derivatives
|
|
WO2001008636A2
(en)
|
1999-08-03 |
2001-02-08 |
The Ohio State University |
Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein
|
|
EP1221971A2
(en)
|
1999-09-24 |
2002-07-17 |
SmithKline Beecham Biologics SA |
Use of the combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines
|
|
CA2383110A1
(en)
|
1999-09-24 |
2001-03-29 |
Veronique Henderickx |
Adjuvant comprising a polyoxyethylene alkyl ether or ester and at least one non-ionic surfactant
|
|
IL149034A0
(en)
|
1999-11-05 |
2002-11-10 |
Astrazeneca Ab |
Quinazoline derivatives as vegf inhibitors
|
|
CN102172398A
(zh)
|
2000-01-17 |
2011-09-07 |
诺华疫苗和诊断有限公司 |
含有脑膜炎奈瑟球菌b血清群外膜蛋白质的外膜囊(omv)疫苗
|
|
AT409085B
(de)
|
2000-01-28 |
2002-05-27 |
Cistem Biotechnologies Gmbh |
Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
|
|
RS50444B
(sr)
|
2000-02-15 |
2010-03-02 |
Sugen Inc. |
Inhibitori 2-indolinon protein kinaze supstituisani pirolom
|
|
AU2001253427B2
(en)
|
2000-04-12 |
2007-02-08 |
Genaera Corporation |
A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group
|
|
JP4102185B2
(ja)
|
2000-06-30 |
2008-06-18 |
グラクソ グループ リミテッド |
キナゾリンジトシル酸塩化合物
|
|
CA2426440C
(en)
|
2000-08-18 |
2011-03-15 |
Millennium Pharmaceuticals, Inc. |
Quinazoline derivatives as kinase inhibitors
|
|
AU8743001A
(en)
|
2000-08-28 |
2002-03-13 |
Aventis Pasteur |
Moraxella polypeptides and corresponding dna fragments and uses thereof
|
|
US6677450B2
(en)
|
2000-10-06 |
2004-01-13 |
Bristol-Myers Squibb Company |
Topoisomerase inhibitors
|
|
IL154853A0
(en)
|
2000-10-27 |
2003-10-31 |
Chiron Spa |
Nucleic acids and proteins from streptococcus groups a & b
|
|
WO2002062826A1
(fr)
|
2001-02-07 |
2002-08-15 |
Vadim Viktorovich Novikov |
Procede de fabrication des peptides
|
|
EP1399181B1
(en)
|
2001-05-18 |
2012-05-09 |
The Government of the USA, as represented by the Secretary, Dept. of Health and Human Services, Centers for Disease Control and Prevention |
Peptide vaccines against group a streptococci
|
|
US20040186172A1
(en)
|
2001-07-02 |
2004-09-23 |
Houssam Ibrahim |
Oxaliplatin active substance with a very low content of oxalic acid
|
|
KR100484504B1
(ko)
|
2001-09-18 |
2005-04-20 |
학교법인 포항공과대학교 |
쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물
|
|
US20030134846A1
(en)
|
2001-10-09 |
2003-07-17 |
Schering Corporation |
Treatment of trypanosoma brucei with farnesyl protein transferase inhibitors
|
|
GB0126879D0
(en)
*
|
2001-11-08 |
2002-01-02 |
Astrazeneca Ab |
Combination therapy
|
|
EP1485082A4
(en)
|
2002-02-19 |
2009-12-30 |
Xenoport Inc |
PROCESS FOR THE SYNTHESIS OF PROMEDICAMENTS FROM 1-ACYL-ALKYL DERIVATIVES AND CORRESPONDING COMPOSITIONS
|
|
GB0210128D0
(en)
|
2002-05-02 |
2002-06-12 |
Chiron Spa |
Nucleic acids and proteins from streptococcus groups A & B
|
|
US6900342B2
(en)
|
2002-05-10 |
2005-05-31 |
Dabur India Limited |
Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
|
|
US6727272B1
(en)
|
2002-07-15 |
2004-04-27 |
Unitech Pharmaceuticals, Inc. |
Leflunomide analogs for treating rheumatoid arthritis
|
|
US20040047835A1
(en)
*
|
2002-09-06 |
2004-03-11 |
Cell Therapeutics, Inc. |
Combinatorial drug therapy using polymer drug conjugates
|
|
WO2004041157A2
(en)
|
2002-09-13 |
2004-05-21 |
Chiron Corporation |
Group b streptococcus vaccine
|
|
US20060067947A1
(en)
*
|
2002-09-19 |
2006-03-30 |
Orient Cancer Therapy Co., Ltd. |
Immunotherapeutic for cancer
|
|
US20100255002A1
(en)
|
2003-06-26 |
2010-10-07 |
Chiron Corporation |
Immunogenic compositions for chlamydia trachomatis
|
|
WO2005032582A2
(en)
|
2003-07-31 |
2005-04-14 |
Chiron Corporation |
Immunogenic compositions for streptococcus pyogenes
|