|
BE567431A
(OSRAM)
|
1957-05-07 |
|
|
|
|
US4323581A
(en)
|
1978-07-31 |
1982-04-06 |
Johnson & Johnson |
Method of treating carcinogenesis
|
|
IE52670B1
(en)
|
1981-03-03 |
1988-01-20 |
Leo Ab |
Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
US4806352A
(en)
|
1986-04-15 |
1989-02-21 |
Ribi Immunochem Research Inc. |
Immunological lipid emulsion adjuvant
|
|
ATE60999T1
(de)
|
1986-12-19 |
1991-03-15 |
Duphar Int Res |
Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension.
|
|
DE3752123T2
(de)
|
1987-03-09 |
1998-05-14 |
Kyowa Hakko Kogyo Kk |
Derivate des physiologisch aktiven mittels k-252
|
|
ES2052685T3
(es)
|
1987-03-17 |
1994-07-16 |
Akzo Nv |
Metodo para producir un adyuvante libre.
|
|
EP0383919A4
(en)
|
1988-02-04 |
1992-08-05 |
Kyowa Hakko Kogyo Co., Ltd. |
Staurosporin derivatives
|
|
NZ227850A
(en)
|
1988-02-10 |
1991-11-26 |
Hoffmann La Roche |
Indole substituted pyrrole derivatives; preparatory process and medicaments for use against inflammatory immunological, bronchopulmonary or vascular disorders
|
|
DE3841091A1
(de)
|
1988-12-07 |
1990-06-13 |
Behringwerke Ag |
Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
CA2006700A1
(en)
|
1989-01-17 |
1990-07-17 |
Antonello Pessi |
Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
CA2011896C
(en)
|
1989-04-21 |
2001-05-08 |
Mark Werner |
Ringworm vaccine
|
|
EP0474727B1
(en)
|
1989-05-19 |
1997-07-23 |
Genentech, Inc. |
Her2 extracellular domain
|
|
HU212924B
(en)
|
1989-05-25 |
1996-12-30 |
Chiron Corp |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
AU645760B2
(en)
|
1989-08-04 |
1994-01-27 |
Berlex Laboratories, Inc. |
C-erbb-2 external domain: GP75
|
|
US5439936A
(en)
|
1989-10-03 |
1995-08-08 |
The Regents Of The University Of California |
Method of treating certain tumors using illudin analogs
|
|
IT1237764B
(it)
|
1989-11-10 |
1993-06-17 |
Eniricerche Spa |
Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
|
|
DE69113564T2
(de)
|
1990-08-13 |
1996-05-30 |
American Cyanamid Co |
Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
|
|
US5153312A
(en)
|
1990-09-28 |
1992-10-06 |
American Cyanamid Company |
Oligosaccharide conjugate vaccines
|
|
US5284652A
(en)
|
1990-10-26 |
1994-02-08 |
Pier Allan C |
Dermatophyte vaccine
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
WO1993007153A1
(en)
|
1991-10-10 |
1993-04-15 |
Schering Corporation |
4'-(n-substituted-n-oxide)staurosporine derivatives
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
JPH07505124A
(ja)
|
1991-11-08 |
1995-06-08 |
ザ ユニバーシティ オブ サザン カリフォルニア |
ニューロトロフィン活性増強のためのk−252化合物を含む組成物
|
|
AU671971B2
(en)
|
1991-11-29 |
1996-09-19 |
Chiron Corporation |
Anti-cancer immunotherapeutic vector constructs
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
CA2383007A1
(en)
|
1992-03-02 |
1993-09-16 |
Chiron S.P.A. |
Helicobacter pylori proteins useful for vaccines and diagnostics
|
|
IT1262896B
(it)
|
1992-03-06 |
1996-07-22 |
|
Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
|
|
US5756494A
(en)
|
1992-07-24 |
1998-05-26 |
Cephalon, Inc. |
Protein kinase inhibitors for treatment of neurological disorders
|
|
US5621100A
(en)
|
1992-07-24 |
1997-04-15 |
Cephalon, Inc. |
K-252a derivatives for treatment of neurological disorders
|
|
DE69331228T4
(de)
|
1992-09-21 |
2002-09-05 |
Kyowa Hakko Kogyo Co., Ltd. |
Heilmittel für thrombozytopenia
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
CZ288182B6
(en)
|
1993-07-15 |
2001-05-16 |
Minnesota Mining & Mfg |
Imidazo[4,5-c]pyridine-4-amines and pharmaceutical preparations based thereon
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
US5624949A
(en)
|
1993-12-07 |
1997-04-29 |
Eli Lilly And Company |
Protein kinase C inhibitors
|
|
AU1339895A
(en)
|
1993-12-23 |
1995-07-10 |
Eli Lilly And Company |
Protein kinase c inhibitors
|
|
US6083903A
(en)
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
EP1110953B1
(en)
|
1995-03-30 |
2009-10-28 |
Pfizer Products Inc. |
Quinazoline derivatives
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US6331555B1
(en)
|
1995-06-01 |
2001-12-18 |
University Of California |
Treatment of platelet derived growth factor related disorders such as cancers
|
|
US5747498A
(en)
*
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
GB9513261D0
(en)
|
1995-06-29 |
1995-09-06 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5554519A
(en)
|
1995-08-07 |
1996-09-10 |
Fermalogic, Inc. |
Process of preparing genistein
|
|
WO1997007081A2
(en)
|
1995-08-11 |
1997-02-27 |
Yale University |
Glycosylated indolocarbazole synthesis
|
|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
IL123568A
(en)
|
1995-12-08 |
2001-08-08 |
Janssen Pharmaceutica Nv |
History (Imidazole - 5Il) Methyl-2-quinolinone inhibitors of Prenzyl transferase, their preparation, pharmaceutical preparations containing them and their preparation and drugs containing them
|
|
WO1997037026A1
(en)
|
1996-04-02 |
1997-10-09 |
Smithkline Beecham Corporation |
Novel compounds
|
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
|
EP0934336A1
(en)
|
1996-05-14 |
1999-08-11 |
Smithkline Beecham Corporation |
Novel compounds
|
|
KR100447918B1
(ko)
|
1996-07-25 |
2005-09-28 |
동아제약주식회사 |
대장을포함한위장관보호작용을갖는플라본및플라바논화합물
|
|
DE19630390A1
(de)
|
1996-07-26 |
1998-01-29 |
Chiron Behring Gmbh & Co |
Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung
|
|
AU725733B2
(en)
|
1996-09-04 |
2000-10-19 |
Takara Bio Inc. |
Fungal antigens and process for producing the same
|
|
US5908934A
(en)
|
1996-09-26 |
1999-06-01 |
Bristol-Myers Squibb Company |
Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs
|
|
ES2241042T3
(es)
|
1996-10-11 |
2005-10-16 |
The Regents Of The University Of California |
Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora.
|
|
US6420135B1
(en)
|
1996-10-31 |
2002-07-16 |
Human Genome Sciences, Inc. |
Streptococcus pneumoniae polynucleotides and sequences
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6299881B1
(en)
|
1997-03-24 |
2001-10-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
|
|
ATE432348T1
(de)
|
1997-06-06 |
2009-06-15 |
Univ California |
Inhibitoren von immunstimulatorischen dna sequenz aktivität
|
|
GB9712347D0
(en)
|
1997-06-14 |
1997-08-13 |
Smithkline Beecham Biolog |
Vaccine
|
|
GB9713156D0
(en)
|
1997-06-20 |
1997-08-27 |
Microbiological Res Authority |
Vaccines
|
|
US6800744B1
(en)
|
1997-07-02 |
2004-10-05 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
|
|
ATE311884T1
(de)
|
1997-07-12 |
2005-12-15 |
Cancer Rec Tech Ltd |
Cyclin-abhängige-kinase inhibierende purinderivate
|
|
US5948413A
(en)
|
1997-07-17 |
1999-09-07 |
Board Of Trustees Operating Michigan State University |
Method and vaccine for treatment of pythiosis insidiosi in humans and lower animals
|
|
EP1009382B1
(en)
|
1997-09-05 |
2003-06-18 |
GlaxoSmithKline Biologicals S.A. |
Oil in water emulsions containing saponins
|
|
DE69836977T2
(de)
|
1997-11-21 |
2007-10-18 |
Serono Genetics Institute S.A. |
Chlamydia pneumoniae genomische sequenzen und polypeptiden, fragmenten und anwendungen davon für nachweis, prevention und heilung
|
|
KR100769104B1
(ko)
|
1997-11-28 |
2007-10-23 |
세로노 제네틱스 인스티튜트 에스.에이. |
클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도
|
|
UA67760C2
(uk)
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
|
GB9800569D0
(en)
*
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
US6303114B1
(en)
|
1998-03-05 |
2001-10-16 |
The Medical College Of Ohio |
IL-12 enhancement of immune responses to T-independent antigens
|
|
GB9807721D0
(en)
|
1998-04-08 |
1998-06-10 |
Chiron Spa |
Antigen
|
|
EP1069910A1
(en)
|
1998-04-09 |
2001-01-24 |
GlaxoSmithKline Biologicals S.A. |
Adjuvant compositions
|
|
GB9810193D0
(en)
|
1998-05-12 |
1998-07-08 |
Smithkline Beecham Biolog |
Novel compounds
|
|
DK2020408T3
(da)
|
1998-05-29 |
2013-09-30 |
Sugen Inc |
Pyrrol-substitueret 2-indolinon som proteinkinaseinhibitor
|
|
AU765401B2
(en)
|
1998-09-30 |
2003-09-18 |
Wrair Walter Reed Army Institute Of Research |
Indolo(2,1-b)quinazole-6,12-dione antimalarial compounds and methods of treating malaria therewith
|
|
BR9914374A
(pt)
|
1998-10-09 |
2002-09-17 |
Chiron Corp |
Sequências genÈmicas de neisseria e métodos para seu uso
|
|
PL201482B1
(pl)
|
1998-10-16 |
2009-04-30 |
Smithkline Beecham Biolog |
Sposoby wytwarzania kompozycji szczepionki oraz kompozycja szczepionki
|
|
US20030083242A1
(en)
|
1998-11-06 |
2003-05-01 |
Alphonse Galdes |
Methods and compositions for treating or preventing peripheral neuropathies
|
|
CA2350775A1
(en)
|
1998-11-12 |
2000-05-18 |
The Regents Of The University Of California |
Chlamydia pneumoniae genome sequence
|
|
GB9828000D0
(en)
|
1998-12-18 |
1999-02-10 |
Chiron Spa |
Antigens
|
|
DK1163000T3
(da)
|
1999-03-19 |
2008-04-28 |
Glaxosmithkline Biolog Sa |
Vacciner imod antigener fra bakterier
|
|
DK1187629T3
(da)
|
1999-04-19 |
2005-01-17 |
Glaxosmithkline Biolog Sa |
Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid
|
|
WO2000067161A2
(en)
|
1999-05-04 |
2000-11-09 |
Grant Lee H |
Method and apparatus for categorizing and retrieving network pages and sites
|
|
US6806266B1
(en)
|
1999-07-13 |
2004-10-19 |
Kyowa Hakko Kogyo Co., Ltd. |
Staurosporin derivatives
|
|
JP4658423B2
(ja)
|
1999-08-03 |
2011-03-23 |
ザ オハイオ ステイト ユニバーシティ |
Her−2タンパク質に対する免疫反応性を増強するためのポリペプチドおよびポリヌクレオチド
|
|
BR0014285A
(pt)
|
1999-09-24 |
2002-05-21 |
Smithkline Beecham Biolog |
Adjuvantes compreendendo um éster ou éter de alquila de polioxietileno e pelo menos um tensoativo não-iÈnico
|
|
PL355163A1
(en)
|
1999-09-24 |
2004-04-05 |
Smithkline Beecham Biologicals S.A. |
Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines
|
|
JP3522727B2
(ja)
*
|
1999-11-05 |
2004-04-26 |
アストラゼネカ アクチボラグ |
Vegf阻害剤としてのキナゾリン誘導体
|
|
CA2871789C
(en)
|
2000-01-17 |
2017-04-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
|
|
AT409085B
(de)
|
2000-01-28 |
2002-05-27 |
Cistem Biotechnologies Gmbh |
Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
|
|
PT1255752E
(pt)
|
2000-02-15 |
2007-10-17 |
Pharmacia & Upjohn Co Llc |
Inibidores de proteína quinases: 2-indolinonas substituídas com pirrolo
|
|
WO2001079255A1
(en)
|
2000-04-12 |
2001-10-25 |
Genaera Corporation |
A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group
|
|
CZ300945B6
(cs)
|
2000-06-30 |
2009-09-23 |
Glaxo Group Limited |
Zpusob prípravy 5-(6-chinazolinyl)-furan-2-karbaldehydu
|
|
JP5073147B2
(ja)
*
|
2000-08-18 |
2012-11-14 |
ミレニアム ファーマシューティカルズ インク. |
キナーゼインヒビターとしてのキナゾリン誘導体
|
|
AU8743001A
(en)
|
2000-08-28 |
2002-03-13 |
Aventis Pasteur |
Moraxella polypeptides and corresponding dna fragments and uses thereof
|
|
US6677450B2
(en)
|
2000-10-06 |
2004-01-13 |
Bristol-Myers Squibb Company |
Topoisomerase inhibitors
|
|
ES2330083T3
(es)
|
2000-10-27 |
2009-12-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Acidos nucleicos y proteinas de estreptococos de los grupos a y b.
|
|
WO2002062826A1
(fr)
|
2001-02-07 |
2002-08-15 |
Vadim Viktorovich Novikov |
Procede de fabrication des peptides
|
|
ATE557041T1
(de)
|
2001-05-18 |
2012-05-15 |
Us Gov Health & Human Serv |
Peptid-vakzinen gegen streptokokken der gruppe a
|
|
WO2003004505A1
(en)
|
2001-07-02 |
2003-01-16 |
Debiopharm S.A. |
Oxaliplatin active substance with a very low content of oxalic acid
|
|
KR100484504B1
(ko)
|
2001-09-18 |
2005-04-20 |
학교법인 포항공과대학교 |
쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물
|
|
US20030134846A1
(en)
|
2001-10-09 |
2003-07-17 |
Schering Corporation |
Treatment of trypanosoma brucei with farnesyl protein transferase inhibitors
|
|
GB0126879D0
(en)
*
|
2001-11-08 |
2002-01-02 |
Astrazeneca Ab |
Combination therapy
|
|
US6927036B2
(en)
|
2002-02-19 |
2005-08-09 |
Xero Port, Inc. |
Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
|
|
GB0210128D0
(en)
|
2002-05-02 |
2002-06-12 |
Chiron Spa |
Nucleic acids and proteins from streptococcus groups A & B
|
|
US6900342B2
(en)
|
2002-05-10 |
2005-05-31 |
Dabur India Limited |
Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
|
|
US6727272B1
(en)
|
2002-07-15 |
2004-04-27 |
Unitech Pharmaceuticals, Inc. |
Leflunomide analogs for treating rheumatoid arthritis
|
|
US20040047835A1
(en)
*
|
2002-09-06 |
2004-03-11 |
Cell Therapeutics, Inc. |
Combinatorial drug therapy using polymer drug conjugates
|
|
ES2504166T3
(es)
|
2002-09-13 |
2014-10-08 |
Novartis Vaccines And Diagnostics, Inc. |
Vacuna de estreptococo del grupo B
|
|
AU2003264488A1
(en)
*
|
2002-09-19 |
2004-04-08 |
Orient Cancer Therapy Co., Ltd. |
Immunotherapeutic for cancer
|
|
JP4896715B2
(ja)
|
2003-06-26 |
2012-03-14 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
Chlamydiatrachomatisに対する免疫原性組成物
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ES2505695T3
(es)
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2003-07-31 |
2014-10-10 |
Novartis Vaccines And Diagnostics, Inc. |
Composiciones inmunógenas para Streptococcus pyogenes
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