JP2008502652A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008502652A5 JP2008502652A5 JP2007515945A JP2007515945A JP2008502652A5 JP 2008502652 A5 JP2008502652 A5 JP 2008502652A5 JP 2007515945 A JP2007515945 A JP 2007515945A JP 2007515945 A JP2007515945 A JP 2007515945A JP 2008502652 A5 JP2008502652 A5 JP 2008502652A5
- Authority
- JP
- Japan
- Prior art keywords
- disorder
- piperazine
- phenyl
- dimethyl
- pain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 125000000217 alkyl group Chemical group 0.000 claims 9
- 208000002193 Pain Diseases 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 7
- 208000035475 disorder Diseases 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 206010012289 Dementia Diseases 0.000 claims 4
- 206010034912 Phobia Diseases 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 125000001475 halogen functional group Chemical group 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 208000019906 panic disease Diseases 0.000 claims 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 208000030814 Eating disease Diseases 0.000 claims 3
- 208000019454 Feeding and Eating disease Diseases 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- 235000014632 disordered eating Nutrition 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 208000019899 phobic disease Diseases 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- 208000011580 syndromic disease Diseases 0.000 claims 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 3
- 208000007848 Alcoholism Diseases 0.000 claims 2
- 208000019901 Anxiety disease Diseases 0.000 claims 2
- 206010013654 Drug abuse Diseases 0.000 claims 2
- 208000010228 Erectile Dysfunction Diseases 0.000 claims 2
- 208000026139 Memory disease Diseases 0.000 claims 2
- 208000019022 Mood disease Diseases 0.000 claims 2
- 206010043269 Tension headache Diseases 0.000 claims 2
- 208000008548 Tension-Type Headache Diseases 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000000304 alkynyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 201000001881 impotence Diseases 0.000 claims 2
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 2
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 201000000980 schizophrenia Diseases 0.000 claims 2
- 208000011117 substance-related disease Diseases 0.000 claims 2
- -1 trifluoromethoxy, cyano, hydroxy, amino Chemical group 0.000 claims 2
- QBCRLXQUJLABTJ-BDAKNGLRSA-N (2S,5R)-1-(2,4-dichlorophenyl)-2,5-dimethylpiperazine Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(Cl)C=C1Cl QBCRLXQUJLABTJ-BDAKNGLRSA-N 0.000 claims 1
- LLCVJOUSQWFUMB-WONCBZRYSA-N (2S,5R)-1-(4-bromophenyl)-2,5-dimethylpiperazine (2R,6S)-1-(3,4-dichlorophenyl)-2,6-dimethylpiperazine Chemical compound BrC1=CC=C(C=C1)N1[C@H](CN[C@@H](C1)C)C.ClC=1C=C(C=CC1Cl)N1[C@H](CNC[C@H]1C)C LLCVJOUSQWFUMB-WONCBZRYSA-N 0.000 claims 1
- GFIKSVSRASGOJZ-MNOVXSKESA-N (2r,5s)-1,2,5-trimethyl-4-[4-(trifluoromethoxy)phenyl]piperazine Chemical compound C[C@H]1CN(C)[C@H](C)CN1C1=CC=C(OC(F)(F)F)C=C1 GFIKSVSRASGOJZ-MNOVXSKESA-N 0.000 claims 1
- SZBCAUWSHDMHKY-KGLIPLIRSA-N (2r,5s)-1,2,5-trimethyl-4-naphthalen-2-ylpiperazine Chemical compound C[C@H]1CN(C)[C@H](C)CN1C1=CC=C(C=CC=C2)C2=C1 SZBCAUWSHDMHKY-KGLIPLIRSA-N 0.000 claims 1
- FXNKLCHHIDVQGQ-AOOOYVTPSA-N (2r,6s)-1-(3,4-dichlorophenyl)-2,4,6-trimethylpiperazine Chemical compound C[C@H]1CN(C)C[C@@H](C)N1C1=CC=C(Cl)C(Cl)=C1 FXNKLCHHIDVQGQ-AOOOYVTPSA-N 0.000 claims 1
- GFTNJKQACYLZBC-AOOOYVTPSA-N (2r,6s)-4-(3,4-dichlorophenyl)-1,2,6-trimethylpiperazine Chemical compound C1[C@@H](C)N(C)[C@@H](C)CN1C1=CC=C(Cl)C(Cl)=C1 GFTNJKQACYLZBC-AOOOYVTPSA-N 0.000 claims 1
- IUZVLRITXJIHDA-ZJUUUORDSA-N (2s,5r)-1-(3,4-dichlorophenyl)-2,4,5-trimethylpiperazine Chemical compound C[C@H]1CN(C)[C@H](C)CN1C1=CC=C(Cl)C(Cl)=C1 IUZVLRITXJIHDA-ZJUUUORDSA-N 0.000 claims 1
- RQBSJPVCBLCIHM-BDAKNGLRSA-N (2s,5r)-1-(3,4-dichlorophenyl)-2,5-dimethylpiperazine Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(Cl)C(Cl)=C1 RQBSJPVCBLCIHM-BDAKNGLRSA-N 0.000 claims 1
- FKRWBIHTHXSCHW-ZJUUUORDSA-N (2s,5r)-1-(4-chlorophenyl)-2,5-dimethylpiperazine Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(Cl)C=C1 FKRWBIHTHXSCHW-ZJUUUORDSA-N 0.000 claims 1
- WJPJROLUNXGIEF-OLZOCXBDSA-N (2s,5r)-1-(6-methoxynaphthalen-2-yl)-2,5-dimethylpiperazine Chemical compound C1=CC2=CC(OC)=CC=C2C=C1N1C[C@@H](C)NC[C@@H]1C WJPJROLUNXGIEF-OLZOCXBDSA-N 0.000 claims 1
- WWYSQOYEMMMWAV-ZJUUUORDSA-N (2s,5r)-2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]piperazine Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(OC(F)(F)F)C=C1 WWYSQOYEMMMWAV-ZJUUUORDSA-N 0.000 claims 1
- FYDUFKKWJFNDSY-ZJUUUORDSA-N (2s,5r)-2,5-dimethyl-1-[4-(trifluoromethyl)phenyl]piperazine Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(C(F)(F)F)C=C1 FYDUFKKWJFNDSY-ZJUUUORDSA-N 0.000 claims 1
- RDYDGIGERJSAHE-OLZOCXBDSA-N (2s,5r)-2,5-dimethyl-1-naphthalen-2-ylpiperazine Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(C=CC=C2)C2=C1 RDYDGIGERJSAHE-OLZOCXBDSA-N 0.000 claims 1
- VZJCZXJTOZWTCS-DTORHVGOSA-N (3r,5s)-1-(2,4-dichlorophenyl)-3,5-dimethylpiperazine Chemical compound C1[C@@H](C)N[C@@H](C)CN1C1=CC=C(Cl)C=C1Cl VZJCZXJTOZWTCS-DTORHVGOSA-N 0.000 claims 1
- BZAQWSNRVXZSGP-DTORHVGOSA-N (3r,5s)-1-(3,4-dichlorophenyl)-3,5-dimethylpiperazine Chemical compound C1[C@@H](C)N[C@@H](C)CN1C1=CC=C(Cl)C(Cl)=C1 BZAQWSNRVXZSGP-DTORHVGOSA-N 0.000 claims 1
- PACRVVKTZKPNEA-UHFFFAOYSA-N 1-(3,4-dichlorophenyl)-3-methylpiperazine Chemical compound C1CNC(C)CN1C1=CC=C(Cl)C(Cl)=C1 PACRVVKTZKPNEA-UHFFFAOYSA-N 0.000 claims 1
- 208000030507 AIDS Diseases 0.000 claims 1
- 201000004384 Alopecia Diseases 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000000044 Amnesia Diseases 0.000 claims 1
- 206010003591 Ataxia Diseases 0.000 claims 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 claims 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 claims 1
- 206010003805 Autism Diseases 0.000 claims 1
- 208000020706 Autistic disease Diseases 0.000 claims 1
- 208000008035 Back Pain Diseases 0.000 claims 1
- 208000020925 Bipolar disease Diseases 0.000 claims 1
- 208000032841 Bulimia Diseases 0.000 claims 1
- 206010006550 Bulimia nervosa Diseases 0.000 claims 1
- XHOLWVDNPHOZHI-MNOVXSKESA-N C[C@H]1CN(C)[C@H](C)CN1C1=CC=C(Cl)C=C1 Chemical compound C[C@H]1CN(C)[C@H](C)CN1C1=CC=C(Cl)C=C1 XHOLWVDNPHOZHI-MNOVXSKESA-N 0.000 claims 1
- OGQVPHNJYFVDEX-ZJUUUORDSA-N C[C@H]1CN[C@H](C)CN1C1=CC=C(I)C=C1 Chemical compound C[C@H]1CN[C@H](C)CN1C1=CC=C(I)C=C1 OGQVPHNJYFVDEX-ZJUUUORDSA-N 0.000 claims 1
- 206010058019 Cancer Pain Diseases 0.000 claims 1
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 claims 1
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 208000022497 Cocaine-Related disease Diseases 0.000 claims 1
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 claims 1
- 208000027534 Emotional disease Diseases 0.000 claims 1
- 208000026097 Factitious disease Diseases 0.000 claims 1
- 208000001640 Fibromyalgia Diseases 0.000 claims 1
- 208000011688 Generalised anxiety disease Diseases 0.000 claims 1
- 206010065390 Inflammatory pain Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 208000019695 Migraine disease Diseases 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 208000028389 Nerve injury Diseases 0.000 claims 1
- 206010029216 Nervousness Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000027089 Parkinsonian disease Diseases 0.000 claims 1
- 206010034010 Parkinsonism Diseases 0.000 claims 1
- 208000004983 Phantom Limb Diseases 0.000 claims 1
- 206010056238 Phantom pain Diseases 0.000 claims 1
- 208000008348 Post-Concussion Syndrome Diseases 0.000 claims 1
- 208000004550 Postoperative Pain Diseases 0.000 claims 1
- 206010036618 Premenstrual syndrome Diseases 0.000 claims 1
- 206010052276 Pseudodementia Diseases 0.000 claims 1
- 208000005793 Restless legs syndrome Diseases 0.000 claims 1
- 201000001880 Sexual dysfunction Diseases 0.000 claims 1
- 206010041250 Social phobia Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000011962 Substance-induced mood disease Diseases 0.000 claims 1
- 231100000395 Substance-induced mood disorder Toxicity 0.000 claims 1
- 206010043903 Tobacco abuse Diseases 0.000 claims 1
- 208000000323 Tourette Syndrome Diseases 0.000 claims 1
- 208000031674 Traumatic Acute Stress disease Diseases 0.000 claims 1
- 206010046543 Urinary incontinence Diseases 0.000 claims 1
- 208000026345 acute stress disease Diseases 0.000 claims 1
- 201000007930 alcohol dependence Diseases 0.000 claims 1
- 230000036506 anxiety Effects 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 claims 1
- 208000025748 atypical depressive disease Diseases 0.000 claims 1
- 208000029028 brain injury Diseases 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 201000001272 cocaine abuse Diseases 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 206010013663 drug dependence Diseases 0.000 claims 1
- 210000001097 facial muscle Anatomy 0.000 claims 1
- 208000029364 generalized anxiety disease Diseases 0.000 claims 1
- 210000002816 gill Anatomy 0.000 claims 1
- 208000024963 hair loss Diseases 0.000 claims 1
- 230000003676 hair loss Effects 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 206010020765 hypersomnia Diseases 0.000 claims 1
- 230000000938 luteal effect Effects 0.000 claims 1
- 238000012423 maintenance Methods 0.000 claims 1
- 208000024714 major depressive disease Diseases 0.000 claims 1
- 230000006984 memory degeneration Effects 0.000 claims 1
- 230000007074 memory dysfunction Effects 0.000 claims 1
- 206010027175 memory impairment Diseases 0.000 claims 1
- 208000023060 memory loss Diseases 0.000 claims 1
- 206010027599 migraine Diseases 0.000 claims 1
- 208000013465 muscle pain Diseases 0.000 claims 1
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 claims 1
- 210000005036 nerve Anatomy 0.000 claims 1
- 230000008764 nerve damage Effects 0.000 claims 1
- 208000004296 neuralgia Diseases 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 239000002858 neurotransmitter agent Substances 0.000 claims 1
- 230000000422 nocturnal effect Effects 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 150000004885 piperazines Chemical class 0.000 claims 1
- 208000028173 post-traumatic stress disease Diseases 0.000 claims 1
- 201000000484 premenstrual tension Diseases 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 231100000872 sexual dysfunction Toxicity 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 208000020685 sleep-wake disease Diseases 0.000 claims 1
- 201000001716 specific phobia Diseases 0.000 claims 1
- 230000035882 stress Effects 0.000 claims 1
- 201000009032 substance abuse Diseases 0.000 claims 1
- 230000002889 sympathetic effect Effects 0.000 claims 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 claims 1
- 208000004371 toothache Diseases 0.000 claims 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims 1
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200400959 | 2004-06-18 | ||
| US58136304P | 2004-06-22 | 2004-06-22 | |
| PCT/EP2005/052732 WO2005123707A1 (en) | 2004-06-18 | 2005-06-14 | Novel alkyl substituted piperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008502652A JP2008502652A (ja) | 2008-01-31 |
| JP2008502652A5 true JP2008502652A5 (enExample) | 2008-06-26 |
Family
ID=34981353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007515945A Abandoned JP2008502652A (ja) | 2004-06-18 | 2005-06-14 | モノアミン神経伝達物質再取込み阻害剤としての、新規アルキル置換ピペラジン誘導体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080176856A1 (enExample) |
| EP (1) | EP1761512A1 (enExample) |
| JP (1) | JP2008502652A (enExample) |
| KR (1) | KR20070026605A (enExample) |
| AU (1) | AU2005254726A1 (enExample) |
| CA (1) | CA2570064A1 (enExample) |
| IL (1) | IL178734A0 (enExample) |
| MX (1) | MXPA06014213A (enExample) |
| NO (1) | NO20070329L (enExample) |
| RU (1) | RU2006140687A (enExample) |
| WO (1) | WO2005123707A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7923444B2 (en) | 2005-02-10 | 2011-04-12 | Neurosearch A/S | Alkyl substituted homopiperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| KR100954755B1 (ko) * | 2007-12-17 | 2010-04-27 | 한미약품 주식회사 | (ｒ)-(-)-1-[(4-클로로페닐)페닐메틸]피페라진의 제조방법 |
| JP2011512340A (ja) * | 2008-02-15 | 2011-04-21 | エフ．ホフマン−ラ ロシュ アーゲー | ３−アルキルピペラジン誘導体及びその使用 |
| US9446230B1 (en) | 2014-09-04 | 2016-09-20 | Advanced Bionics Ag | Cochlear implant electrode array and method for inserting the same into a human cochlea |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB115649A (en) * | 1916-09-07 | 1918-05-23 | David John Scott | Improvements in Web Printing Machines. |
| US3192208A (en) * | 1962-07-31 | 1965-06-29 | Lilly Co Eli | Novel substituted morpholines and piperazines and processes for their synthesis |
| US3247206A (en) * | 1962-10-05 | 1966-04-19 | Ciba Geigy Corp | Diaza-cycloalkane synthesis |
| US3520929A (en) * | 1966-10-19 | 1970-07-21 | Exxon Research Engineering Co | Hexafluoro-2-propanol-2-amines |
| CA2144669A1 (en) * | 1994-03-29 | 1995-09-30 | Kozo Akasaka | Biphenyl derivatives |
| SE9904723D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| US7144883B2 (en) * | 2001-06-11 | 2006-12-05 | Biovitrum Ab | Bicyclic sulfonamide compounds |
| KR101255356B1 (ko) * | 2002-06-12 | 2013-04-17 | 케모센트릭스, 인크. | 염증 및 면역 질병의 치료를 위한 ｃｃｒ１ 길항물질로서사용하기 위한 1-아릴-4-치환된 피페라진 유도체 |
| AU2004265243A1 (en) * | 2003-06-20 | 2005-02-24 | Arena Pharmaceuticals, Inc. | N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5HT2c receptor associated diseases |
-
2005
- 2005-06-14 US US11/579,116 patent/US20080176856A1/en not_active Abandoned
- 2005-06-14 WO PCT/EP2005/052732 patent/WO2005123707A1/en not_active Ceased
- 2005-06-14 JP JP2007515945A patent/JP2008502652A/ja not_active Abandoned
- 2005-06-14 MX MXPA06014213A patent/MXPA06014213A/es not_active Application Discontinuation
- 2005-06-14 RU RU2006140687/04A patent/RU2006140687A/ru not_active Application Discontinuation
- 2005-06-14 KR KR1020067026645A patent/KR20070026605A/ko not_active Withdrawn
- 2005-06-14 EP EP05749104A patent/EP1761512A1/en not_active Withdrawn
- 2005-06-14 AU AU2005254726A patent/AU2005254726A1/en not_active Abandoned
- 2005-06-14 CA CA002570064A patent/CA2570064A1/en not_active Abandoned
-
2006
- 2006-10-19 IL IL178734A patent/IL178734A0/en unknown
-
2007
- 2007-01-17 NO NO20070329A patent/NO20070329L/no not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010513392A5 (enExample) | ||
| MA30088B1 (fr) | Phenethylamines substituees possedant une activite serotoninergique et/ou norepinephrinergique | |
| HRP20090640T1 (hr) | Kristalinični oblici (r)-8-kloro-1-metil-2,3,4,5-tetrahidro-1h-3-benzazepin hidroklorida | |
| RU2007139541A (ru) | Производные хромана и хромена и их применение | |
| RU98105169A (ru) | Производные 8-азабицикло[3.2.1]окт-2-ена, их получение и применение | |
| JP2010535738A5 (enExample) | ||
| JP2008502651A5 (enExample) | ||
| NZ592563A (en) | 1-(arylsulfonyl)-4-(piperazin-1-yl)-1h-benzimidazoles as 5-hydroxytryptamine-6 ligands | |
| RU2011123890A (ru) | Кристаллическая форма 4-[2-(2-фторфеноксиметил)фенил]пиперидинового соединения | |
| RU2007106970A (ru) | Новые хромен-2-оновые производные и их применение в качестве ингибиторов обратного захвата моноаминовых нейромедиаторов | |
| JP2009526816A5 (enExample) | ||
| JP2008502652A5 (enExample) | ||
| JP2007520539A5 (enExample) | ||
| RU2006131454A (ru) | Новые производные мочевины и их медицинское применение | |
| JP2008524161A5 (enExample) | ||
| JP2010513391A5 (enExample) | ||
| JP2006517568A5 (enExample) | ||
| JP2006507363A5 (enExample) | ||
| JP2009526023A5 (enExample) | ||
| JP2008502650A5 (enExample) | ||
| RU2006140687A (ru) | Новые алкил-замещенные производные пиперазина и их применение в качестве ингибиторов обратного захвата моноаминовых нейротрансмиттеров | |
| JP2007523206A5 (enExample) | ||
| JP2008519056A5 (enExample) | ||
| JP2008510775A5 (enExample) | ||
| JP2008546826A5 (enExample) |