JP2008501679A - ２’−ニトロベンジル改変型リボヌクレオチド - Google Patents

２’−ニトロベンジル改変型リボヌクレオチド Download PDF

Info

Publication number
JP2008501679A
JP2008501679A JP2007514217A JP2007514217A JP2008501679A JP 2008501679 A JP2008501679 A JP 2008501679A JP 2007514217 A JP2007514217 A JP 2007514217A JP 2007514217 A JP2007514217 A JP 2007514217A JP 2008501679 A JP2008501679 A JP 2008501679A
Authority
JP
Japan
Prior art keywords
ribonucleoside
ribose
rna polymerase
base
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007514217A
Other languages
English (en)
Japanese (ja)
Inventor
オラフ ピーペンブルク，
デレク エル． ステンプル，
ニアル エー． アームズ，
Original Assignee
エーエスエム サイエンティフィック， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エーエスエム サイエンティフィック， インコーポレイテッド filed Critical エーエスエム サイエンティフィック， インコーポレイテッド
Publication of JP2008501679A publication Critical patent/JP2008501679A/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP2007514217A 2004-06-02 2005-06-02 ２’−ニトロベンジル改変型リボヌクレオチド Withdrawn JP2008501679A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57690704P 2004-06-02 2004-06-02
PCT/IB2005/002488 WO2005118608A2 (en) 2004-06-02 2005-06-02 2’-nitrobenzyl-modified ribonucleotides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012013260A Division JP2012095665A (ja) 2004-06-02 2012-01-25 ２’−ニトロベンジル改変型リボヌクレオチド

Publications (1)

Publication Number Publication Date
JP2008501679A true JP2008501679A (ja) 2008-01-24

Family

ID=35463420

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2007514217A Withdrawn JP2008501679A (ja) 2004-06-02 2005-06-02 ２’−ニトロベンジル改変型リボヌクレオチド
JP2012013260A Pending JP2012095665A (ja) 2004-06-02 2012-01-25 ２’−ニトロベンジル改変型リボヌクレオチド
JP2012119854A Pending JP2012157369A (ja) 2004-06-02 2012-05-25 ２’−ニトロベンジル改変型リボヌクレオチド

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012013260A Pending JP2012095665A (ja) 2004-06-02 2012-01-25 ２’−ニトロベンジル改変型リボヌクレオチド
JP2012119854A Pending JP2012157369A (ja) 2004-06-02 2012-05-25 ２’−ニトロベンジル改変型リボヌクレオチド

Country Status (8)

Country Link
US (4) US7759061B2 (enExample)
EP (1) EP1753774B1 (enExample)
JP (3) JP2008501679A (enExample)
AT (1) ATE407939T1 (enExample)
AU (1) AU2005250239A1 (enExample)
CA (1) CA2569491A1 (enExample)
DE (1) DE602005009693D1 (enExample)
WO (1) WO2005118608A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572581B2 (en) 2003-06-30 2009-08-11 Roche Molecular Systems, Inc. 2′-terminator nucleotide-related methods and systems
US7947817B2 (en) 2003-06-30 2011-05-24 Roche Molecular Systems, Inc. Synthesis and compositions of 2'-terminator nucleotides
JP2008501679A (ja) 2004-06-02 2008-01-24 エーエスエム サイエンティフィック， インコーポレイテッド ２’−ニトロベンジル改変型リボヌクレオチド
US7745125B2 (en) * 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
US7928207B2 (en) * 2004-06-28 2011-04-19 Roche Molecular Systems, Inc Synthesis and compositions of nucleic acids comprising 2′-terminator nucleotides
WO2007075967A2 (en) * 2005-12-21 2007-07-05 Roche Diagnostics Gmbh Sequencing and genotyping using reversibly 2'-modified nucleotides
US8399188B2 (en) 2006-09-28 2013-03-19 Illumina, Inc. Compositions and methods for nucleotide sequencing
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
CN105765384B (zh) 2013-09-13 2018-02-09 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
US10351918B2 (en) 2013-10-30 2019-07-16 Green Life Biotech, Llc Pathogenesis quantification systems and treatment methods for citrus greening blight
WO2022232601A1 (en) 2021-04-29 2022-11-03 Abbott Laboratories High throughput nucleic acid testing of biological samples

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5836396A (ja) * 1981-08-24 1983-03-03 Agency Of Ind Science & Technol オリゴリボヌクレオチドの製造法
JPS58109498A (ja) * 1981-08-24 1983-06-29 Agency Of Ind Science & Technol オリゴリボヌクレオチド
WO2000053805A1 (en) * 1999-03-10 2000-09-14 Asm Scientific, Inc. A method for direct nucleic acid sequencing
US6136543A (en) * 1997-01-31 2000-10-24 Hitachi, Ltd. Method for determining nucleic acids base sequence and apparatus therefor
JP2001288197A (ja) * 2000-04-10 2001-10-16 Fuji Photo Film Co Ltd 蛍光ヌクレオチド
WO2002030944A2 (en) * 2000-10-11 2002-04-18 Applera Corporation Fluorescent nucleobase conjugates having anionic linkers
JP2002521495A (ja) * 1998-07-31 2002-07-16 アフィメトリックス インコーポレイテッド 核酸標識化合物
JP2004510433A (ja) * 2000-10-06 2004-04-08 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Ｄｎａおよびｒｎａを解読するための大量並行方法
JP2004511227A (ja) * 2000-10-10 2004-04-15 ザ　パブリック　ヘルス　リサーチ　インスティテュート　オブ　ザ　シティ　オブ　ニューヨーク，インコーポレーテッド 核酸の同種内検出用の特異的二本鎖プローブおよびその適用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223414A (en) 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
CA2122203C (en) * 1993-05-11 2001-12-18 Melinda S. Fraiser Decontamination of nucleic acid amplification reactions
ATE400663T1 (de) 2002-02-21 2008-07-15 Asm Scient Inc Rekombinase-polymerase-amplifikation
EP1759012B1 (en) 2004-06-01 2013-05-22 Alere San Diego, Inc. Recombinase polymerase amplification
JP2008501679A (ja) * 2004-06-02 2008-01-24 エーエスエム サイエンティフィック， インコーポレイテッド ２’−ニトロベンジル改変型リボヌクレオチド

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5836396A (ja) * 1981-08-24 1983-03-03 Agency Of Ind Science & Technol オリゴリボヌクレオチドの製造法
JPS58109498A (ja) * 1981-08-24 1983-06-29 Agency Of Ind Science & Technol オリゴリボヌクレオチド
US6136543A (en) * 1997-01-31 2000-10-24 Hitachi, Ltd. Method for determining nucleic acids base sequence and apparatus therefor
JP2002521495A (ja) * 1998-07-31 2002-07-16 アフィメトリックス インコーポレイテッド 核酸標識化合物
WO2000053805A1 (en) * 1999-03-10 2000-09-14 Asm Scientific, Inc. A method for direct nucleic acid sequencing
JP2001288197A (ja) * 2000-04-10 2001-10-16 Fuji Photo Film Co Ltd 蛍光ヌクレオチド
JP2004510433A (ja) * 2000-10-06 2004-04-08 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Ｄｎａおよびｒｎａを解読するための大量並行方法
JP2004511227A (ja) * 2000-10-10 2004-04-15 ザ　パブリック　ヘルス　リサーチ　インスティテュート　オブ　ザ　シティ　オブ　ニューヨーク，インコーポレーテッド 核酸の同種内検出用の特異的二本鎖プローブおよびその適用方法
WO2002030944A2 (en) * 2000-10-11 2002-04-18 Applera Corporation Fluorescent nucleobase conjugates having anionic linkers

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CHEM. PHARM. BULL., vol. Vol.25(5), JPN6012056218, 1977, pages 949 - 959, ISSN: 0002366734 *
CHEM. PHARM. BULL., vol. Vol.26(8), JPN6012056216, 1978, pages 2396 - 2406, ISSN: 0002366735 *
CHEM. PHARM. BULL., vol. Vol.29(2), JPN6012056220, 1981, pages 318 - 324, ISSN: 0002366733 *
JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. Vol.101(21), JPN6012056214, 1979, pages 6409 - 6414, ISSN: 0002366736 *
METZKER M L, NUCLEIC ACIDS RESEARCH, vol. V22 N20, JPN5007008778, 1994, GB, pages 4259 - 4267, ISSN: 0001999037 *
NUCLEIC ACIDS RESEARCH, vol. 15, no. 18, JPN6012056222, 1987, pages 7235 - 7248, ISSN: 0002366738 *
NUCLEIC ACIDS RESEARCH, vol. 18, no. 13, JPN6012056224, 1990, pages 3831 - 3839, ISSN: 0002366739 *
NUCLEIC ACIDS RESEARCH, vol. 3, no. 11, JPN6012056226, 1976, pages 3203 - 3211, ISSN: 0002366737 *
SHIN,SEUNGJIN, JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. V30 N3, JPN5007008779, 1997, pages 211 - 215, ISSN: 0001999038 *

Also Published As

Publication number Publication date
AU2005250239A1 (en) 2005-12-15
US20110053154A1 (en) 2011-03-03
US7759061B2 (en) 2010-07-20
ATE407939T1 (de) 2008-09-15
US20130045475A1 (en) 2013-02-21
EP1753774A2 (en) 2007-02-21
CA2569491A1 (en) 2005-12-15
JP2012157369A (ja) 2012-08-23
JP2012095665A (ja) 2012-05-24
US20120040345A1 (en) 2012-02-16
WO2005118608A2 (en) 2005-12-15
DE602005009693D1 (de) 2008-10-23
EP1753774B1 (en) 2008-09-10
US8299226B2 (en) 2012-10-30
US20080261208A1 (en) 2008-10-23
US8022194B2 (en) 2011-09-20
WO2005118608A3 (en) 2006-04-27

Similar Documents

Publication Publication Date Title
JP2012095665A (ja) ２’−ニトロベンジル改変型リボヌクレオチド
EP3797170B1 (en) Polynucleotide synthesis method, system and kit
JP5745842B2 (ja) 拡張によるハイスループット核酸配列決定
US7585649B2 (en) Modified oligonucleotides and applications thereof
CN106460052B (zh) 双链核酸的合成
JP3867926B2 (ja) 核酸の増幅法
US20150086981A1 (en) Nucleoside-triphosphate conjugate and methods for the use thereof
JP7509745B2 (ja) ポリヌクレオチド合成方法、キット、およびシステム
WO2008042067A2 (en) Compositions and methods for nucleotide sequencing
US7534569B2 (en) Method of generating long nucleic acid molecules of defined sequence
US6627416B1 (en) 5′-modified nucleotides and the application thereof in molecular biology and medicine
EP1624059A2 (en) Method of producing nucleic acid molecules with reduced secondary structure
JP2008535518A (ja) プソイドイソシトシン核酸塩基誘導体を含む３’改変オリゴヌクレオチド、およびプライマーまたはプローブとしてのその適用
CN114729390A (zh) 寡核苷酸的酶促合成
US11034964B1 (en) Binding molecules built from L-DNA with added nucleotides
JP4942160B2 (ja) ＲｅｃＡタンパク質を利用した核酸の等温増幅法
JP5618227B2 (ja) 核酸の増幅方法および遺伝子変異の検出方法
AU2010321576A1 (en) Devices to extend single stranded target molecules
HK40074774A (en) Enzymatic synthesis of oligonucleotides
JPWO2019150564A1 (ja) スルホンアミド骨格をもつオリゴヌクレオチドを鋳型として用いたｄｎａ複製法
Steck Oligonucleotide-modified Nuclotides
JP2008199969A (ja) 膜タンパク質に特異的に結合する機能性分子およびその作製方法

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080528

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110823

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111122

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111130

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120125

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20120125

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20120328

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121026

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130125

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130201

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130222

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130301

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130325

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130401

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20130419