JP2008297283A - 抗酸化作用を有する組成物 - Google Patents
抗酸化作用を有する組成物 Download PDFInfo
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- JP2008297283A JP2008297283A JP2007147535A JP2007147535A JP2008297283A JP 2008297283 A JP2008297283 A JP 2008297283A JP 2007147535 A JP2007147535 A JP 2007147535A JP 2007147535 A JP2007147535 A JP 2007147535A JP 2008297283 A JP2008297283 A JP 2008297283A
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- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
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Abstract
【解決手段】カンカ加工物及びアシュワガンダ加工物から選択される少なくともいずれか1種と、西洋人参加工物を含有する組成物、さらに高麗人参加工物及び/又はマカ加工物を含有する組成物、該組成物を使用して得られる飲食品、該組成物の製造方法、ならびにカンカおよび/またはアシュワガンダの抗酸化力増強方法を提供する。
【選択図】なし
Description
項1.カンカ加工物及びアシュワガンダ加工物から選択される少なくともいずれか1種と、西洋人参加工物を含有する組成物。
項2.前記加工物が粉砕物、乾燥物及び溶媒抽出物からなる群より選択されるいずれか1種である項1に記載の組成物。
項3.西洋人参加工物の含有量が、カンカ加工物100重量部に対して0.5重量部以上および/またはアシュワガンダ加工物100重量部に対して0.003重量部以上である項1又は2に記載の組成物。
項4.さらに高麗人参加工物及びマカ加工物から選択される少なくともいずれか1種を含有する項1〜3のいずれかに記載の組成物。
項5.経口用組成物である項1〜4のいずれかに記載の組成物。
項6.飲食品の形態である項1〜5のいずれかに記載の組成物。
項7.カンカ加工物及びアシュワガンダ加工物から選択される少なくともいずれか1種に
西洋人参加工物を配合するカンカおよび/またはアシュワガンダの抗酸化力増強方法。
本発明に含まれる加工物は、以下の植物を原料とする。
カンカ(別名:中国砂漠人参)は、カンカニクジュヨウとも呼ばれ、ハマウツボ科(学名;Cistache Tsubulosa )に属し、自然界では砂漠に生育する紅柳(タマリクス)の根部に寄生する。カンカ加工物としては、カンカエキス末(株式会社栄進商事)等を商業的に入手することが可能である。
アシュワガンダ(別名:インド人参)は、ウィンターチェリー、セキトメホウズキとも呼ばれ、ナス科(学名:Withania sominifera)に属し、自然界ではインド、ネパール等の乾燥地に自生する。地中海沿岸では栽培されていることもある。アシュワガンダ加工物としては、アシュワガンダパウダーW(日本新薬株式会社)等を商業的に入手することが可能である。
西洋人参(別名:アメリカ人参)は、花旗参、美国人参、洋人参とも呼ばれ、ウコギ科(学名:Panax quinquefolium)に属する。原産国はアメリカ合衆国、カナダ、フランス等である。西洋人参加工物としては、Ginseng American PE(TOWA CORPORATION 株式会社)等を商業的に入手することが可能である。
高麗人参(別名:朝鮮人参)は、オタネ人参、薬用人参とも呼ばれ、加工方法によって白参、紅参、鬚人参、曲参とも呼ばれる。ウコギ科(学名:Panax ginseng)に属し、中国東北部に原生するものや、中国東北部、ロシア(極東地域)、北朝鮮、韓国、日本(島根、石川、長野、岩手等)で栽培されているものがある。高麗人参加工物としては、エキス末(長岡実業株式会社)等を商業的に入手することが可能である。
マカ(別名:ペルー人参)は、アンデス人参とも呼ばれ、アブラナ科(学名:Lepidium meyanii)に属し、高度3500〜4500mのアンデス高地で栽培されている。マカ加工物としては、マカエキスパウダーMACAXS-HC(TOWA CORPORATION 株式会社)等を商業的に入手することが可能である。
上記(i)〜(v)の成分に加え、必要に応じ、本発明の効果を損なわない範囲で従来公知の着色剤、保存剤、香料、風味剤、コーティング剤、乳化剤等の成分を配合することもできる。
上記本発明の組成物は、上記成分を含む経口用の組成物として調製されることが望ましい。本発明の経口組成物は、抗酸化作用を有する健康食品(栄養機能食品、特定保健用食品、サプリメント等)、病者用食品等が挙げられる。このような飲食品として本発明の飲食品組成物を調製する場合は、上記の組成物をそのまま経口用組成物として使用してもよいし、継続的な摂取が行いやすいように、例えば顆粒剤(ドライシロップを含む)、カプセル剤(軟カプセル剤、硬カプセル剤)、錠剤(チュアブル剤等を含む)、散剤(粉末剤)、丸剤などの各種の固形製剤、または内服用液剤(液剤、懸濁剤、シロップ剤を含む)などの液状製剤等の形態で調製することが望ましく、なかでもカプセル剤、錠剤の形態が各成分の安定性や摂取の簡便さの点からは好ましいが、特に限定されるものではない。
カンカ加工物及びアシュワガンダ加工物から選択される少なくともいずれか1種に、西洋人参加工物を配合することによって、カンカ及びアシュワガンダが本来有する抗酸化力を一層増強することができる。よって、本発明は抗酸化力増強方法をも提供するものである。
下記表1に示されるカンカ、アシュワガンダ、西洋人参、高麗人参、マカの抽出物を、下記表2及び3に示される種々の濃度になるように精製水に溶解して水溶液を調製し、SOD Assay Kit-WST(同仁化学研究所)を用いてSOD様活性を測定した。
(活性上昇率)
◎:110%以上
○:100%以上110%未満
×:100%未満
(錠剤)
賦形剤として、結晶セルロース(80〜150mg)、デンプン(60〜90mg)、ステアリン酸カルシウム(15〜25mg)、デキストリン(5〜10mg)および微粒二酸化ケイ素(2〜8mg)を使用し、表4〜9に記載する処方を、慣用法に従って錠剤として調製した。具体的には、各成分を処方に従って配合し、粉砕、造粒、乾燥、整粒および混合を行い、それを定法に従って打錠して錠剤(180〜450mg)の形態に調製した。
(ソフトカプセル)
賦形剤として、ミツロウ(20〜220mg)、サフラワー油(10〜30mg)、ゼラチン(30〜120mg)およびグリセリン(10〜30mg)を使用し、表4〜9に記載する処方を、慣用法に従ってソフトカプセルとして調製した。具体的には、各成分を処方に従って配合し、定法に従って外皮調製、芯液調製、製球および乾燥を行い、ソフトカプセル(150〜500mg)の形態に調製した。
(顆粒剤)
賦形剤として、デキストリン(500〜1500mg)およびキサンタンガム(200〜400mg)を使用し、表4〜9に記載する処方を、慣用法に従って顆粒剤として調製した。具体的には、各成分を処方に従って配合し、定法に従って混合、造粒、乾燥および整粒して顆粒剤(730mg〜2140mg)の形態に調製した。
Claims (7)
- カンカ加工物及びアシュワガンダ加工物から選択される少なくともいずれか1種と、西洋人参加工物を含有する組成物。
- 前記加工物が粉砕物、乾燥物及び溶媒抽出物からなる群より選択されるいずれか1種である請求項1に記載の組成物。
- 西洋人参加工物の含有量が、カンカ加工物100重量部に対して0.5重量部以上および/またはアシュワガンダ加工物100重量部に対して0.003重量部以上である請求項1又は2に記載の組成物。
- さらに高麗人参加工物及びマカ加工物から選択される少なくともいずれか1種を含有する請求項1〜3のいずれかに記載の組成物。
- 経口用組成物である請求項1〜4のいずれかに記載の組成物。
- 飲食品の形態である請求項1〜5のいずれかに記載の組成物。
- カンカ加工物及びアシュワガンダ加工物から選択される少なくともいずれか1種に西洋人参加工物を配合するカンカおよび/またはアシュワガンダの抗酸化力増強方法。
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ITTO20110412A1 (it) * | 2011-05-11 | 2012-11-12 | Minerva Res Labs Ltd | Bevanda rivitalizzante e rilassante |
US20160000847A1 (en) * | 2014-07-03 | 2016-01-07 | Sinphar Pharmaceutical Co., Ltd. | Method of using cistanche tubulosa extract for preparing drugs or food to protect eye cells |
US10967029B2 (en) | 2014-07-03 | 2021-04-06 | Sinphar Pharmaceutical Co., Ltd. | Method of using Cistanche tubulosa extract to prevent, slow down, or treat an eye disease caused by oxidative stress |
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