JP2007538030A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007538030A5 JP2007538030A5 JP2007517056A JP2007517056A JP2007538030A5 JP 2007538030 A5 JP2007538030 A5 JP 2007538030A5 JP 2007517056 A JP2007517056 A JP 2007517056A JP 2007517056 A JP2007517056 A JP 2007517056A JP 2007538030 A5 JP2007538030 A5 JP 2007538030A5
- Authority
- JP
- Japan
- Prior art keywords
- administration
- rats
- heart
- weeks
- animals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241001465754 Metazoa Species 0.000 description 3
- 241000700159 Rattus Species 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000004072 C09CA03 - Valsartan Substances 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 239000008298 dragée Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 208000010125 myocardial infarction Diseases 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- SJSNUMAYCRRIOM-QFIPXVFZSA-N valsartan Chemical compound C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=N[N]1 SJSNUMAYCRRIOM-QFIPXVFZSA-N 0.000 description 2
- 229960004699 valsartan Drugs 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 229940111134 coxibs Drugs 0.000 description 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000012453 sprague-dawley rat model Methods 0.000 description 1
- 239000007940 sugar coated tablet Substances 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57172904P | 2004-05-17 | 2004-05-17 | |
| US60056704P | 2004-08-11 | 2004-08-11 | |
| PCT/EP2005/005286 WO2005110480A2 (en) | 2004-05-17 | 2005-05-13 | Combination of organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007538030A JP2007538030A (ja) | 2007-12-27 |
| JP2007538030A5 true JP2007538030A5 (https=) | 2008-07-03 |
Family
ID=35134672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007517056A Withdrawn JP2007538030A (ja) | 2004-05-17 | 2005-05-13 | 有機化合物の組合せ剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080280939A1 (https=) |
| EP (1) | EP1755681A2 (https=) |
| JP (1) | JP2007538030A (https=) |
| KR (1) | KR20070012486A (https=) |
| AU (1) | AU2005244437A1 (https=) |
| BR (1) | BRPI0511262A (https=) |
| CA (1) | CA2561717A1 (https=) |
| MX (1) | MXPA06013294A (https=) |
| RU (1) | RU2006144809A (https=) |
| WO (1) | WO2005110480A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1859274A2 (en) * | 2005-03-07 | 2007-11-28 | Novartis AG | Genes involved in neurodegenerative conditions |
| US20080207671A1 (en) * | 2006-07-31 | 2008-08-28 | The Regents Of The University Of Michigan | Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway |
| AU2007287809A1 (en) * | 2006-08-22 | 2008-02-28 | Novartis Ag | Rapamycin and its derivatives for the treatment of liver-associated fibrosing disorders |
| EP2131821B1 (en) | 2007-03-07 | 2018-05-09 | Abraxis BioScience, LLC | Nanoparticle comprising rapamycin and albumin as anticancer agent |
| US20100166869A1 (en) * | 2007-05-03 | 2010-07-01 | Desai Neil P | Methods and compositions for treating pulmonary hypertension |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0306858A (pt) * | 2002-01-10 | 2004-11-03 | Novartis Ag | Sistemas de liberação de drogas para a prevenção e tratamento de doenças vasculares compreendendo rapamicina e derivados da mesma |
| PT1478648E (pt) * | 2002-02-01 | 2014-07-15 | Ariad Pharma Inc | Compostos contendo fósforo e suas utilizações |
-
2005
- 2005-05-13 BR BRPI0511262-1A patent/BRPI0511262A/pt not_active IP Right Cessation
- 2005-05-13 RU RU2006144809/15A patent/RU2006144809A/ru unknown
- 2005-05-13 AU AU2005244437A patent/AU2005244437A1/en not_active Abandoned
- 2005-05-13 US US11/596,943 patent/US20080280939A1/en not_active Abandoned
- 2005-05-13 MX MXPA06013294A patent/MXPA06013294A/es not_active Application Discontinuation
- 2005-05-13 KR KR1020067023980A patent/KR20070012486A/ko not_active Withdrawn
- 2005-05-13 EP EP05744586A patent/EP1755681A2/en not_active Withdrawn
- 2005-05-13 CA CA002561717A patent/CA2561717A1/en not_active Abandoned
- 2005-05-13 WO PCT/EP2005/005286 patent/WO2005110480A2/en not_active Ceased
- 2005-05-13 JP JP2007517056A patent/JP2007538030A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2326167T3 (es) | Comprimidos dispersables de deferasirox. | |
| US20100203133A1 (en) | High drug load tablet | |
| RU2482865C2 (ru) | Фармацевтическая композиция для лечения кардиомиопатии | |
| US20250025496A1 (en) | Zinc-[gamma]-pga compositions and methods for treating cancer | |
| JP6174666B2 (ja) | ナルトレキソンの徐放型配合物 | |
| HUE034393T2 (en) | Increasing drug bioavailability in naltrexone therapy | |
| Baraldo | Meltdose tacrolimus pharmacokinetics | |
| US20060263427A1 (en) | Quinine formulations | |
| Schor et al. | Susadrin transmucosal tablets (nitroglycerin in Synchron® controlled-release base) | |
| BR112020003375A2 (pt) | composições de amantadina, preparações das mesmas, e métodos de uso | |
| JP2007538030A5 (https=) | ||
| CN109893653A (zh) | Pde9抑制剂的新用途 | |
| CN100502874C (zh) | 特定环胺衍生物或其可药用盐制备治疗或预防心力衰竭的药物的用途 | |
| JP5117230B2 (ja) | ２型糖尿病治療用の併用医薬 | |
| JP2018135278A (ja) | 循環器疾患及び／又はミトコンドリア病の改善用医薬 | |
| WO2006088864A1 (en) | Controlled release compositions comprising levetiracetam | |
| HU207219B (en) | Process for producing improved anti-inflammatory composition | |
| CZ79593A3 (en) | Antitussive preparation | |
| NZ207768A (en) | Sustained release tablets comprising dipyridamole | |
| TW200538154A (en) | Combination of organic compounds | |
| ES2346755T3 (es) | Uso de acetato de megestrol para mejorar la funcion cardiaca y el tratamiento de la insuficiencia cardiaca. | |
| RU2543637C2 (ru) | Пролонгированная фармацевтическая композиция гипотензивного действия и способ ее изготовления | |
| Tablets et al. | PrAPO-SAXAGLIPTIN | |
| CA2596768A1 (en) | A method for treating heart failure | |
| CA3235787A1 (en) | Methods of treating patients having type 1 diabetes with eflornithine |