JP2007537005A5 - - Google Patents
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- Publication number
- JP2007537005A5 JP2007537005A5 JP2007513354A JP2007513354A JP2007537005A5 JP 2007537005 A5 JP2007537005 A5 JP 2007537005A5 JP 2007513354 A JP2007513354 A JP 2007513354A JP 2007513354 A JP2007513354 A JP 2007513354A JP 2007537005 A5 JP2007537005 A5 JP 2007537005A5
- Authority
- JP
- Japan
- Prior art keywords
- article
- group
- coating
- natural biodegradable
- polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004676 glycans Chemical class 0.000 claims 23
- 229920001282 polysaccharide Polymers 0.000 claims 23
- 239000005017 polysaccharide Substances 0.000 claims 23
- 239000011248 coating agent Substances 0.000 claims 14
- 238000000576 coating method Methods 0.000 claims 14
- 125000005647 linker group Chemical group 0.000 claims 11
- 239000012867 bioactive agent Substances 0.000 claims 8
- 239000011159 matrix material Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 5
- 229920000856 Amylose Polymers 0.000 claims 3
- 229920002774 Maltodextrin Polymers 0.000 claims 3
- 239000005913 Maltodextrin Substances 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 239000008199 coating composition Substances 0.000 claims 3
- 229940035034 maltodextrin Drugs 0.000 claims 3
- 239000004005 microsphere Substances 0.000 claims 3
- 239000003505 polymerization initiator Substances 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- WROUWQQRXUBECT-UHFFFAOYSA-N 2-ethylacrylic acid Chemical group CCC(=C)C(O)=O WROUWQQRXUBECT-UHFFFAOYSA-N 0.000 claims 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical group NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- 229920000945 Amylopectin Polymers 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 1
- 229920000045 Dermatan sulfate Polymers 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 229920002971 Heparan sulfate Polymers 0.000 claims 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 1
- 229920000288 Keratan sulfate Polymers 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 208000007536 Thrombosis Diseases 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M acrylate group Chemical group C(C=C)(=O)[O-] NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 239000003080 antimitotic agent Substances 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 108010089934 carbohydrase Proteins 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940045110 chitosan Drugs 0.000 claims 1
- 229940059329 chondroitin sulfate Drugs 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 claims 1
- 229940051593 dermatan sulfate Drugs 0.000 claims 1
- 229960002086 dextran Drugs 0.000 claims 1
- 229960000633 dextran sulfate Drugs 0.000 claims 1
- 229920000669 heparin Polymers 0.000 claims 1
- 229960002897 heparin Drugs 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 claims 1
- LVHBHZANLOWSRM-UHFFFAOYSA-N itaconic acid Chemical group OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 claims 1
- KXCLCNHUUKTANI-RBIYJLQWSA-N keratan Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@H](COS(O)(=O)=O)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H]([C@@H](COS(O)(=O)=O)O[C@@H](O)[C@@H]3O)O)[C@H](NC(C)=O)[C@H]2O)COS(O)(=O)=O)O[C@H](COS(O)(=O)=O)[C@@H]1O KXCLCNHUUKTANI-RBIYJLQWSA-N 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical group CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M methacrylate group Chemical group C(C(=C)C)(=O)[O-] CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229940043138 pentosan polysulfate Drugs 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 229940032147 starch Drugs 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 125000003011 styrenyl group Chemical group [H]\C(*)=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57033404P | 2004-05-12 | 2004-05-12 | |
| US60/570,334 | 2004-05-12 | ||
| US60370704P | 2004-08-23 | 2004-08-23 | |
| US60/603,707 | 2004-08-23 | ||
| US61366204P | 2004-09-28 | 2004-09-28 | |
| US60/613,662 | 2004-09-28 | ||
| PCT/US2005/016604 WO2005113034A1 (en) | 2004-05-12 | 2005-05-12 | Natural biodegradable polysaccharides coatings for medical articles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007537005A JP2007537005A (ja) | 2007-12-20 |
| JP2007537005A5 true JP2007537005A5 (https=) | 2008-06-19 |
| JP5026956B2 JP5026956B2 (ja) | 2012-09-19 |
Family
ID=35063157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513354A Expired - Fee Related JP5026956B2 (ja) | 2004-05-12 | 2005-05-12 | 医療用具のための天然生分解性多糖コーティング |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8241655B2 (https=) |
| EP (1) | EP1755696A1 (https=) |
| JP (1) | JP5026956B2 (https=) |
| CA (1) | CA2564588A1 (https=) |
| WO (1) | WO2005113034A1 (https=) |
Families Citing this family (83)
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| CA2621657C (en) * | 2005-09-21 | 2014-06-17 | Surmodics, Inc. | In situ occluding compositions comprising natural biodegradable polysaccharides polymerized by a redox pair |
| US20070065483A1 (en) * | 2005-09-21 | 2007-03-22 | Chudzik Stephen J | In vivo formed matrices including natural biodegradable polysaccharides and uses thereof |
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| CN103126971A (zh) * | 2005-11-17 | 2013-06-05 | 雷文斯治疗公司 | 减少非毒素蛋白质的肉毒杆菌毒素组合物和其局部施用及透皮递送方法 |
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| JP2009535104A (ja) * | 2006-04-25 | 2009-10-01 | サーモディクス，インコーポレイティド | 挿入可能な親水性の形状記憶医療製品 |
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| ATE269114T1 (de) * | 1998-11-20 | 2004-07-15 | Univ Connecticut | Verfahren und vorrichtung zur steuerung der gewebeimplantat-interaktionen |
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-
2005
- 2005-05-12 EP EP05748196A patent/EP1755696A1/en not_active Withdrawn
- 2005-05-12 JP JP2007513354A patent/JP5026956B2/ja not_active Expired - Fee Related
- 2005-05-12 CA CA002564588A patent/CA2564588A1/en not_active Abandoned
- 2005-05-12 WO PCT/US2005/016604 patent/WO2005113034A1/en not_active Ceased
- 2005-05-12 US US11/127,351 patent/US8241655B2/en not_active Expired - Fee Related
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