JP2007537005A5 - - Google Patents
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- Publication number
- JP2007537005A5 JP2007537005A5 JP2007513354A JP2007513354A JP2007537005A5 JP 2007537005 A5 JP2007537005 A5 JP 2007537005A5 JP 2007513354 A JP2007513354 A JP 2007513354A JP 2007513354 A JP2007513354 A JP 2007513354A JP 2007537005 A5 JP2007537005 A5 JP 2007537005A5
- Authority
- JP
- Japan
- Prior art keywords
- article
- group
- coating
- natural biodegradable
- polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004676 glycans Chemical class 0.000 claims 23
- 229920001282 polysaccharide Polymers 0.000 claims 23
- 239000005017 polysaccharide Substances 0.000 claims 23
- 239000011248 coating agent Substances 0.000 claims 14
- 238000000576 coating method Methods 0.000 claims 14
- 125000005647 linker group Chemical group 0.000 claims 11
- 239000012867 bioactive agent Substances 0.000 claims 8
- 239000011159 matrix material Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 5
- 229920000856 Amylose Polymers 0.000 claims 3
- 229920002774 Maltodextrin Polymers 0.000 claims 3
- 239000005913 Maltodextrin Substances 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 239000008199 coating composition Substances 0.000 claims 3
- 229940035034 maltodextrin Drugs 0.000 claims 3
- 239000004005 microsphere Substances 0.000 claims 3
- 239000003505 polymerization initiator Substances 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- WROUWQQRXUBECT-UHFFFAOYSA-N 2-ethylacrylic acid Chemical group CCC(=C)C(O)=O WROUWQQRXUBECT-UHFFFAOYSA-N 0.000 claims 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical group NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- 229920000945 Amylopectin Polymers 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 1
- 229920000045 Dermatan sulfate Polymers 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 229920002971 Heparan sulfate Polymers 0.000 claims 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 1
- 229920000288 Keratan sulfate Polymers 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 208000007536 Thrombosis Diseases 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M acrylate group Chemical group C(C=C)(=O)[O-] NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 239000003080 antimitotic agent Substances 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 108010089934 carbohydrase Proteins 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940045110 chitosan Drugs 0.000 claims 1
- 229940059329 chondroitin sulfate Drugs 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 claims 1
- 229940051593 dermatan sulfate Drugs 0.000 claims 1
- 229960002086 dextran Drugs 0.000 claims 1
- 229960000633 dextran sulfate Drugs 0.000 claims 1
- 229920000669 heparin Polymers 0.000 claims 1
- 229960002897 heparin Drugs 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 claims 1
- LVHBHZANLOWSRM-UHFFFAOYSA-N itaconic acid Chemical group OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 claims 1
- KXCLCNHUUKTANI-RBIYJLQWSA-N keratan Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@H](COS(O)(=O)=O)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H]([C@@H](COS(O)(=O)=O)O[C@@H](O)[C@@H]3O)O)[C@H](NC(C)=O)[C@H]2O)COS(O)(=O)=O)O[C@H](COS(O)(=O)=O)[C@@H]1O KXCLCNHUUKTANI-RBIYJLQWSA-N 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical group CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M methacrylate group Chemical group C(C(=C)C)(=O)[O-] CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229940043138 pentosan polysulfate Drugs 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 229940032147 starch Drugs 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 125000003011 styrenyl group Chemical group [H]\C(*)=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57033404P | 2004-05-12 | 2004-05-12 | |
| US60/570,334 | 2004-05-12 | ||
| US60370704P | 2004-08-23 | 2004-08-23 | |
| US60/603,707 | 2004-08-23 | ||
| US61366204P | 2004-09-28 | 2004-09-28 | |
| US60/613,662 | 2004-09-28 | ||
| PCT/US2005/016604 WO2005113034A1 (en) | 2004-05-12 | 2005-05-12 | Natural biodegradable polysaccharides coatings for medical articles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007537005A JP2007537005A (ja) | 2007-12-20 |
| JP2007537005A5 true JP2007537005A5 (enExample) | 2008-06-19 |
| JP5026956B2 JP5026956B2 (ja) | 2012-09-19 |
Family
ID=35063157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513354A Expired - Fee Related JP5026956B2 (ja) | 2004-05-12 | 2005-05-12 | 医療用具のための天然生分解性多糖コーティング |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8241655B2 (enExample) |
| EP (1) | EP1755696A1 (enExample) |
| JP (1) | JP5026956B2 (enExample) |
| CA (1) | CA2564588A1 (enExample) |
| WO (1) | WO2005113034A1 (enExample) |
Families Citing this family (84)
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| US6007833A (en) | 1998-03-19 | 1999-12-28 | Surmodics, Inc. | Crosslinkable macromers bearing initiator groups |
| WO1999059638A2 (en) * | 1998-05-15 | 1999-11-25 | Chiron Corporation | Compositions and methods for the delivery of nucleic acid molecules |
| FR2780901B1 (fr) | 1998-07-09 | 2000-09-29 | Coletica | Particules, en particulier micro- ou nanoparticules de monosaccharides et oligosaccharides reticules, leurs procedes de preparation et compositions cosmetiques, pharmaceutiques ou alimentaires en contenant |
| DE69924749T2 (de) * | 1998-11-20 | 2006-04-27 | The University Of Connecticut, Farmington | Generisch integrierte implantierbare Potentiostatfernmeßanordnung für elektrochemische Fühler |
| ES2298135T3 (es) * | 1999-04-12 | 2008-05-16 | Cornell Research Foundation, Inc. | Sistema formador de hidrogel con componentes hidrofobos e hidrofilos. |
| US6716445B2 (en) | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
| US6586493B1 (en) | 2001-03-07 | 2003-07-01 | Arizona Board Of Regents Arizona State University | Polysaccharide-based hydrogels and pre-gel blends for the same |
| TW200407367A (en) * | 2001-11-13 | 2004-05-16 | Novartis Ag | Method for modifying the surface of biomedical articles |
| JP2005526972A (ja) | 2002-05-02 | 2005-09-08 | シファーゲン バイオシステムズ， インコーポレイテッド | 多糖系ヒドロゲルをコーティングした表面を有するバイオチップ |
| DE10223310A1 (de) * | 2002-05-24 | 2003-12-11 | Biotronik Mess & Therapieg | Verfahren zum Beschichten von Implantaten mit einer Polysaccharid-Lage |
| US20040062778A1 (en) | 2002-09-26 | 2004-04-01 | Adi Shefer | Surface dissolution and/or bulk erosion controlled release compositions and devices |
| CA2509382A1 (en) | 2002-12-17 | 2004-07-08 | Todd C. Zion | Stimuli-responsive systems for controlled drug delivery |
| WO2007038126A1 (en) | 2005-09-21 | 2007-04-05 | Surmodics, Inc. | In vivo formed matrices including natural biodegradable polysaccharides and ophthalmic uses thereof |
| CA2621595A1 (en) | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
-
2005
- 2005-05-12 WO PCT/US2005/016604 patent/WO2005113034A1/en not_active Ceased
- 2005-05-12 JP JP2007513354A patent/JP5026956B2/ja not_active Expired - Fee Related
- 2005-05-12 US US11/127,351 patent/US8241655B2/en not_active Expired - Fee Related
- 2005-05-12 EP EP05748196A patent/EP1755696A1/en not_active Withdrawn
- 2005-05-12 CA CA002564588A patent/CA2564588A1/en not_active Abandoned
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