JP2007535478A5 - - Google Patents
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- JP2007535478A5 JP2007535478A5 JP2006520420A JP2006520420A JP2007535478A5 JP 2007535478 A5 JP2007535478 A5 JP 2007535478A5 JP 2006520420 A JP2006520420 A JP 2006520420A JP 2006520420 A JP2006520420 A JP 2006520420A JP 2007535478 A5 JP2007535478 A5 JP 2007535478A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- formula
- group
- independently selected
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 125000001424 substituent group Chemical group 0.000 description 9
- 125000000623 heterocyclic group Chemical group 0.000 description 5
- 125000001072 heteroaryl group Chemical group 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 3
- 125000003118 aryl group Chemical group 0.000 description 2
- 125000004093 cyano group Chemical group *C#N 0.000 description 2
- 229910052736 halogen Inorganic materials 0.000 description 2
- 150000002367 halogens Chemical class 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 125000003373 pyrazinyl group Chemical group 0.000 description 2
- 125000002098 pyridazinyl group Chemical group 0.000 description 2
- 125000000714 pyrimidinyl group Chemical group 0.000 description 2
- 125000002861 (C1-C4) alkanoyl group Chemical group 0.000 description 1
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 description 1
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 description 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 description 1
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 description 1
- 125000003341 7 membered heterocyclic group Chemical group 0.000 description 1
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 description 1
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 description 1
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 description 1
- 125000001313 C5-C10 heteroaryl group Chemical group 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 description 1
- 125000000304 alkynyl group Chemical group 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 125000000468 ketone group Chemical group 0.000 description 1
- 125000004076 pyridyl group Chemical group 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48694803P | 2003-07-14 | 2003-07-14 | |
| PCT/US2004/023776 WO2005007652A2 (en) | 2003-07-14 | 2004-07-14 | Substituted quinolin-4-ylamine analogues |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011032423A Division JP2011137018A (ja) | 2003-07-14 | 2011-02-17 | 置換キノリン−４−イルアミン類縁体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007535478A JP2007535478A (ja) | 2007-12-06 |
| JP2007535478A5 true JP2007535478A5 (https=) | 2011-04-07 |
Family
ID=34079320
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006520420A Abandoned JP2007535478A (ja) | 2003-07-14 | 2004-07-14 | 置換キノリン−４−イルアミン類縁体 |
| JP2011032423A Pending JP2011137018A (ja) | 2003-07-14 | 2011-02-17 | 置換キノリン−４−イルアミン類縁体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011032423A Pending JP2011137018A (ja) | 2003-07-14 | 2011-02-17 | 置換キノリン−４−イルアミン類縁体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7488740B2 (https=) |
| EP (1) | EP1644372A2 (https=) |
| JP (2) | JP2007535478A (https=) |
| CN (1) | CN1820008A (https=) |
| AU (1) | AU2004257296A1 (https=) |
| CA (1) | CA2531535A1 (https=) |
| TW (1) | TW200510373A (https=) |
| WO (1) | WO2005007652A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2509233A1 (en) * | 2002-12-13 | 2004-07-01 | Neurogen Corporation | 2-substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators |
| JP4695395B2 (ja) * | 2002-12-13 | 2011-06-08 | ニューロジェン・コーポレーション | 疼痛治療用の併用療法 |
| TW200510373A (en) * | 2003-07-14 | 2005-03-16 | Neurogen Corp | Substituted quinolin-4-ylamine analogues |
| JP2007520444A (ja) * | 2003-09-09 | 2007-07-26 | ニューロジェン・コーポレーション | 置換二環式キナゾリン−４−イルアミン誘導体 |
| EP1720542A4 (en) * | 2004-03-04 | 2007-11-28 | Neurogen Corp | ARYL ALKYLAMINO-SUBSTITUTED CHINAZOLINE ANALOGUE |
| JP2007532570A (ja) * | 2004-04-08 | 2007-11-15 | ニューロジェン・コーポレーション | 置換シンノリン−４−イルアミン類 |
| TW200621251A (en) * | 2004-10-12 | 2006-07-01 | Neurogen Corp | Substituted biaryl quinolin-4-ylamine analogues |
| WO2007042906A1 (en) | 2005-10-07 | 2007-04-19 | Glenmark Pharmaceuticals S.A. | Substituted benzofused derivatives and their use as vanilloid receptor ligands |
| US7915411B2 (en) | 2005-12-21 | 2011-03-29 | Abbott Laboratories | Anti-viral compounds |
| EP1979348B1 (en) | 2005-12-21 | 2012-01-18 | Abbott Laboratories | Anti-viral compounds |
| ATE475660T1 (de) * | 2005-12-21 | 2010-08-15 | Abbott Lab | Antivirale verbindungen |
| EA201300152A1 (ru) | 2006-11-27 | 2013-07-30 | Х. Лундбекк А/С | Гетероариламидные производные |
| US8236950B2 (en) | 2006-12-20 | 2012-08-07 | Abbott Laboratories | Anti-viral compounds |
| JP2010043063A (ja) * | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
| US8546388B2 (en) * | 2008-10-24 | 2013-10-01 | Purdue Pharma L.P. | Heterocyclic TRPV1 receptor ligands |
| US8703962B2 (en) * | 2008-10-24 | 2014-04-22 | Purdue Pharma L.P. | Monocyclic compounds and their use as TRPV1 ligands |
| US8759362B2 (en) * | 2008-10-24 | 2014-06-24 | Purdue Pharma L.P. | Bicycloheteroaryl compounds and their use as TRPV1 ligands |
| WO2011043954A1 (en) * | 2009-10-07 | 2011-04-14 | Merck Sharp & Dohme Corp. | Novel trpa1 antagonists |
| MX2013010163A (es) | 2011-03-09 | 2013-10-30 | Merck Patent Gmbh | Derivados de pirido[2,3-b] pirazina y sus usos terapeuticos. |
| WO2013188813A2 (en) * | 2012-06-15 | 2013-12-19 | The Regents Of The University Of California | Novel therapeutics for brain cancer |
| HRP20201384T1 (hr) | 2014-01-01 | 2020-11-27 | Medivation Technologies Llc | Spojevi i postupci njihove upotrebe |
| US10227333B2 (en) | 2015-02-11 | 2019-03-12 | Curtana Pharmaceuticals, Inc. | Inhibition of OLIG2 activity |
| BR112017018198A2 (pt) * | 2015-02-27 | 2018-04-10 | Curtana Pharmaceuticals Inc | inibição da atividade de olig2 |
| WO2017031427A1 (en) * | 2015-08-19 | 2017-02-23 | 3-V Biosciences, Inc. | COMPOUNDS AND METHODS FOR INHIBITING mTOR |
| US20220056043A1 (en) * | 2019-02-19 | 2022-02-24 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Nitrogen-containing fused cyclic compound, preparation method therefor and use thereof |
| DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8928281D0 (en) * | 1989-12-14 | 1990-02-21 | Smith Kline French Lab | Compounds |
| GB9510757D0 (en) | 1994-09-19 | 1995-07-19 | Wellcome Found | Therapeuticaly active compounds |
| AR004010A1 (es) * | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| GB9603097D0 (en) * | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline compounds |
| HRP970371A2 (en) * | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
| ID19609A (id) * | 1996-07-13 | 1998-07-23 | Glaxo Group Ltd | Senyawa-senyawa heterosiklik |
| ES2191187T3 (es) * | 1996-07-13 | 2003-09-01 | Glaxo Group Ltd | Compuestos heteroaromaticos biciclicos como inhibidores de la proteina tirosin-quinasa. |
| US5863016A (en) * | 1997-02-28 | 1999-01-26 | The Wiremold Company | Modular faceplate assembly having concealed latching means |
| MA26473A1 (fr) * | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
| RS49779B (sr) * | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze |
| BR9914164A (pt) * | 1998-09-29 | 2001-06-26 | American Cyanamid Co | Composto, método para o tratamento, inibição do crescimento de, ou erradiacação de um neoplasma, e de doença de rim policìstico, em um mamìfero em necessidade do mesmo, composição farmacêutica, e, processo para preparar um composto |
| GB2345486A (en) | 1999-01-11 | 2000-07-12 | Glaxo Group Ltd | Heteroaromatic protein tyrosine kinase inhibitors |
| US6521618B2 (en) * | 2000-03-28 | 2003-02-18 | Wyeth | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors |
| JP2004525071A (ja) | 2000-07-20 | 2004-08-19 | ニューロジェン コーポレイション | カプサイシン受容体リガンド |
| EP1317450B1 (en) | 2000-09-15 | 2006-11-22 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| JP2005501873A (ja) * | 2001-07-31 | 2005-01-20 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | アミン誘導体 |
| CN1627944A (zh) * | 2002-01-17 | 2005-06-15 | 神经能质公司 | 取代的喹唑啉－4－基胺类似物作为辣椒辣素调节剂 |
| EP1538907A4 (en) * | 2002-07-02 | 2008-12-24 | Southern Res Inst | FTSZ-HEMMER AND ITS USE |
| JP4695395B2 (ja) * | 2002-12-13 | 2011-06-08 | ニューロジェン・コーポレーション | 疼痛治療用の併用療法 |
| CA2509233A1 (en) | 2002-12-13 | 2004-07-01 | Neurogen Corporation | 2-substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators |
| TW200510373A (en) * | 2003-07-14 | 2005-03-16 | Neurogen Corp | Substituted quinolin-4-ylamine analogues |
| TW200621251A (en) * | 2004-10-12 | 2006-07-01 | Neurogen Corp | Substituted biaryl quinolin-4-ylamine analogues |
| AU2006208042A1 (en) | 2005-01-25 | 2006-08-03 | Neurogen Corporation | Substituted pyridazinyl-and pyrimidinyl-quinolin-4-ylamine analogues |
-
2004
- 2004-07-13 TW TW093120845A patent/TW200510373A/zh unknown
- 2004-07-14 CA CA002531535A patent/CA2531535A1/en not_active Abandoned
- 2004-07-14 CN CNA2004800197211A patent/CN1820008A/zh active Pending
- 2004-07-14 US US10/891,832 patent/US7488740B2/en not_active Expired - Fee Related
- 2004-07-14 AU AU2004257296A patent/AU2004257296A1/en not_active Abandoned
- 2004-07-14 JP JP2006520420A patent/JP2007535478A/ja not_active Abandoned
- 2004-07-14 EP EP04779026A patent/EP1644372A2/en not_active Withdrawn
- 2004-07-14 WO PCT/US2004/023776 patent/WO2005007652A2/en not_active Ceased
-
2009
- 2009-02-09 US US12/368,302 patent/US20090286767A1/en not_active Abandoned
-
2011
- 2011-02-17 JP JP2011032423A patent/JP2011137018A/ja active Pending
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