JP2007532666A5 - - Google Patents
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- JP2007532666A5 JP2007532666A5 JP2007508498A JP2007508498A JP2007532666A5 JP 2007532666 A5 JP2007532666 A5 JP 2007532666A5 JP 2007508498 A JP2007508498 A JP 2007508498A JP 2007508498 A JP2007508498 A JP 2007508498A JP 2007532666 A5 JP2007532666 A5 JP 2007532666A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antiviral composition
- group
- nuclease
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56193404P | 2004-04-14 | 2004-04-14 | |
| PCT/US2005/012532 WO2005115444A2 (en) | 2004-04-14 | 2005-04-14 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007532666A JP2007532666A (ja) | 2007-11-15 |
| JP2007532666A5 true JP2007532666A5 (https=) | 2008-07-03 |
Family
ID=35451407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007508498A Pending JP2007532666A (ja) | 2004-04-14 | 2005-04-14 | ウイルス核酸を対象とした修飾ヌクレアーゼを用いた組成物及びウイルス性疾患の予防並びに治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9592277B2 (https=) |
| EP (1) | EP1734991A4 (https=) |
| JP (1) | JP2007532666A (https=) |
| AU (2) | AU2005247298B8 (https=) |
| CA (1) | CA2604243C (https=) |
| IL (1) | IL178802A0 (https=) |
| WO (1) | WO2005115444A2 (https=) |
Families Citing this family (50)
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| US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| US9248166B2 (en) | 2003-07-14 | 2016-02-02 | Cls Therapeutics Limited | Method for treating oncological diseases |
| WO2006130034A1 (fr) * | 2005-04-25 | 2006-12-07 | Dmitry Dmitrievich Genkin | Procede pour prolonger la duree de vie d'animaux ou de l'humain |
| US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
| US8710012B2 (en) * | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US9592277B2 (en) * | 2004-04-14 | 2017-03-14 | Avirid, Inc. | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
| WO2007133812A2 (en) * | 2005-12-30 | 2007-11-22 | Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine | Improved carriers for delivery of nucleic acid agents to cells and tissues |
| EP1987055A1 (en) * | 2006-02-10 | 2008-11-05 | Dermagen AB | Novel antimicrobial peptides and use thereof |
| US8840882B2 (en) * | 2006-06-23 | 2014-09-23 | Quintessence Biosciences, Inc. | Modified ribonucleases |
| WO2008034123A2 (en) * | 2006-09-15 | 2008-03-20 | Enzon Pharmaceuticals, Inc. | Polymeric conjugates containing positively-charged moieties |
| US8871200B2 (en) | 2006-11-28 | 2014-10-28 | Cls Therapeutics Limited | Method for treating human diseases associated with an increased deoxyribonucleic acid content in extracellular spaces of tissues and a medicinal preparation for carrying out said method |
| US9296790B2 (en) | 2008-10-03 | 2016-03-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for protein delivery |
| WO2011031467A1 (en) * | 2009-08-25 | 2011-03-17 | Wayne State University | Anti-cancer therapeutic strategy to overcome cancer resistance and to enable tailoring treatment to patients |
| GB0922066D0 (en) | 2009-12-17 | 2010-02-03 | Univ Belfast | Modulator |
| CA2787260A1 (en) * | 2010-01-18 | 2011-07-21 | Zhi-Min Yuan | Methods and compositions for nanoparticle-mediated cancer cell-targeted delivery |
| KR101341640B1 (ko) * | 2010-02-05 | 2013-12-16 | 한국전자통신연구원 | 단백질 미세 구조 분석 방법 및 단백질 미세 구조 분석용 어레이 |
| JP5794541B2 (ja) * | 2010-04-21 | 2015-10-14 | 国立大学法人北海道大学 | 核内移行性を有する脂質膜構造体 |
| EP2490021A1 (en) * | 2011-02-18 | 2012-08-22 | Biotempt B.V. | Modulators of PRR and GPCR signalling |
| WO2013126872A1 (en) * | 2012-02-24 | 2013-08-29 | Wayne State University | Anti-cancer therapeutic strategy to overcome cancer resistance and to enable tailoring treatment to patients |
| AU2013240248B2 (en) | 2012-03-26 | 2018-12-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Delivery of packaged RNA to mammalian cells |
| CA2898184A1 (en) | 2013-01-16 | 2014-07-24 | Emory University | Cas9-nucleic acid complexes and uses related thereto |
| WO2014197091A2 (en) * | 2013-03-15 | 2014-12-11 | Techulon Inc. | Rapidly adaptable nano therapeutics for treatment of infectious disease |
| US11306326B2 (en) | 2013-08-23 | 2022-04-19 | Rutgers, The State University Of New Jersey | Biologically active synthetic nanoparticle constructs and methods of use thereof |
| WO2015027243A2 (en) * | 2013-08-23 | 2015-02-26 | Rutgers The State University Of New Jersey | Biologically active synthetic nanoparticle constructs and mehtods of use therof |
| CN106232807A (zh) | 2013-12-16 | 2016-12-14 | 美利坚合众国, 由健康及人类服务部部长代表 | 通过使用vlp复制子投递ii类mhc抗原的癌症免疫疗法 |
| US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
| KR20170080579A (ko) | 2014-10-01 | 2017-07-10 | 플랜트 헬스 케어, 인코포레이티드 | 파괴된 과민성 반응 박스를 갖는 유발제 펩티드 및 그의 용도 |
| CA2962951A1 (en) | 2014-10-01 | 2016-04-07 | Plant Health Care, Inc. | Hypersensitive response elicitor peptides and use thereof |
| ES2799515T3 (es) | 2015-05-22 | 2020-12-18 | Dmitry Dmitrievich Genkin | ADN extracelular como una diana terapéutica en la neurodegeneración |
| US10117911B2 (en) | 2015-05-29 | 2018-11-06 | Agenovir Corporation | Compositions and methods to treat herpes simplex virus infections |
| CN116082457A (zh) | 2016-02-01 | 2023-05-09 | 堪培拉大学 | 蛋白化合物及其用途 |
| WO2019090390A1 (en) | 2017-11-08 | 2019-05-16 | University Of Canberra | Immunogenic compositions and uses therefor |
| WO2019099685A1 (en) | 2017-11-15 | 2019-05-23 | Rutgers, The State University Of New Jersey | Biodegradable hybrid inorganic nanoscaffolding materials and methods of use and manufacture thereof |
| CN111712468A (zh) | 2017-12-22 | 2020-09-25 | 北卡罗莱纳州立大学 | 聚合物荧光团、包含其的组合物及制备和使用其的方法 |
| AU2019209770B2 (en) | 2018-01-16 | 2025-07-31 | Cls Therapeutics Limited | Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity |
| EP3821003A4 (en) * | 2018-07-09 | 2022-07-20 | Gro Biosciences Inc. | Non-standard amino acid containing compositions and uses thereof |
| WO2020106709A1 (en) * | 2018-11-19 | 2020-05-28 | Gro Biosciences Inc. | Human dnase for lung disease |
| JP7469318B2 (ja) * | 2019-01-28 | 2024-04-16 | マイクロベンション インコーポレイテッド | コーティング |
| US12478684B2 (en) * | 2019-04-11 | 2025-11-25 | Northeastern University | Oligonucleotide-polymer miktoarm conjugates and methods of use |
| WO2021046307A1 (en) * | 2019-09-04 | 2021-03-11 | North Carolina State University | Hybridized poly(amidoamine)-amino acid dendrimers |
| WO2021150867A1 (en) * | 2020-01-24 | 2021-07-29 | Sarepta Therapeutics, Inc. | Designing antisense oligonucleotide delivery peptides by interpretable machine learning |
| WO2021231499A2 (en) * | 2020-05-11 | 2021-11-18 | Revir, Inc. | Compositions and methods for treating viral infections |
| CA3178744C (en) | 2020-05-13 | 2023-11-14 | Ardythe L. Morrow | Fucosylated oligosaccharides for prevention of coronavirus infection |
| WO2021231750A1 (en) * | 2020-05-13 | 2021-11-18 | Glycosyn LLC | 2'-fucosyllactose for the prevention and treatment of coronavirus-induced inflammation |
| WO2022026689A1 (en) | 2020-07-30 | 2022-02-03 | Microvention, Inc. | Antimicrobial coatings |
| US20220040315A1 (en) | 2020-08-09 | 2022-02-10 | Fulu Labs Corporation | Nuclease-dendrimer formulations for covid-19 and broad-spectrum antiviral therapy and prophylaxis |
| EP4203968A4 (en) * | 2020-08-31 | 2025-07-30 | Starpharma Pty Ltd | DENDRIMER-DRUG CONJUGATE |
| CN117651550A (zh) * | 2021-07-02 | 2024-03-05 | 奥古尔·米尔扎尤索夫娜·穆萨哈诺娃 | 用于预防SARS-CoV-2感染的药物 |
| CN114250208B (zh) * | 2021-12-22 | 2023-07-25 | 武汉瀚海新酶生物科技有限公司 | 耐高盐高活性DNase I突变体的制备及应用 |
| WO2024092230A2 (en) * | 2022-10-28 | 2024-05-02 | The Regents Of The University Of California | Recombinant enhanced antiviral restrictors |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5115096A (en) | 1988-04-15 | 1992-05-19 | Oncogen | Amphiregulin: a bifunctional growth modulating glycoprotein |
| WO1990010015A1 (en) * | 1989-02-23 | 1990-09-07 | Seragen, Inc. | Chimeric toxin |
| US5629173A (en) * | 1990-08-09 | 1997-05-13 | Genentech, Inc. | Methods of use of serine protease variants having peptide ligase activity |
| US5989886A (en) * | 1991-01-02 | 1999-11-23 | The Johns Hopkins University | Method for the inhibition and prevention of viral replication using fusions of a virus protein and a destructive enzyme |
| US5792640A (en) | 1992-04-03 | 1998-08-11 | The Johns Hopkins University | General method to clone hybrid restriction endonucleases using lig gene |
| US5484589A (en) | 1992-04-20 | 1996-01-16 | Rufeld, Inc. | Anti-viral methods using RNAse and DNAse |
| US5503973A (en) | 1992-05-29 | 1996-04-02 | The Regents Of The University Of California | Method for inhibition of viral morphogenesis |
| AU7212694A (en) | 1993-06-24 | 1995-01-17 | Rufeld, Inc. | Inhibition of human immunodeficiency virus reproduction by deoxyribonuclease i |
| RU2066551C1 (ru) | 1994-03-23 | 1996-09-20 | Институт нефтехимического синтеза РАН | Способ получения инсулинсодержащих полимерных гидрогелей |
| US20030053982A1 (en) | 1994-09-26 | 2003-03-20 | Kinstler Olaf B. | N-terminally chemically modified protein compositions and methods |
| US5997861A (en) * | 1994-10-31 | 1999-12-07 | Burstein Laboratories, Inc. | Antiviral supramolecules containing target-binding molecules and therapeutic molecules bound to spectrin |
| US6348343B2 (en) * | 1995-02-24 | 2002-02-19 | Genentech, Inc. | Human DNase I variants |
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| US6214966B1 (en) * | 1996-09-26 | 2001-04-10 | Shearwater Corporation | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution |
| US6280991B1 (en) | 1997-10-15 | 2001-08-28 | Wisconsin Alumni Research Foundation | Engineered cytotoxic ribonclease |
| US6017537A (en) * | 1998-12-18 | 2000-01-25 | Connaught Laboratories, Inc. | Formyl methionyl peptide vaccine adjuvant |
| AU2200100A (en) | 1998-12-21 | 2000-07-12 | Genencor International, Inc. | Chemically modified enzymes with multiple charged variants |
| US6485718B1 (en) | 1999-04-13 | 2002-11-26 | Pharmacia Corporation | Site specific ligation of proteins to synthetic particles |
| ATE340592T1 (de) | 1999-04-23 | 2006-10-15 | Alza Corp | Konjugate enthaltend eine spaltbare bindung zur anwendung in einem liposom |
| US6669951B2 (en) | 1999-08-24 | 2003-12-30 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| US6593292B1 (en) | 1999-08-24 | 2003-07-15 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| US20010053521A1 (en) * | 1999-09-27 | 2001-12-20 | Kreimer David I. | Amplification of analyte detection by substrates having particle structures with receptors |
| US6312956B1 (en) | 1999-10-01 | 2001-11-06 | Vanderbilt University | Nuclear targeted peptide nucleic acid oligomer |
| US6962906B2 (en) | 2000-03-14 | 2005-11-08 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
| EP2213743A1 (en) | 2000-04-12 | 2010-08-04 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US7091026B2 (en) | 2001-02-16 | 2006-08-15 | University Of Iowa Research Foundation | Artificial endonuclease |
| AU2002317437A1 (en) * | 2001-05-18 | 2002-12-03 | Cureon A/S | Therapeutic uses of lna-modified oligonucleotides in infectious diseases |
| US6913903B2 (en) | 2001-09-07 | 2005-07-05 | Nobex Corporation | Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
| GB0126251D0 (en) * | 2001-11-01 | 2002-01-02 | Imp College Innovations Ltd | Methods |
| BR0314236A (pt) | 2002-09-13 | 2005-08-09 | Replicor Inc | Formulação de oligonucleotìdeo, composição farmacêutica, kit, composto antiviral, preparação de oligonucleotìdeo e métodos para seleção de um oligonucleotìdeo antiviral para uso como um agente antiviral, para profilaxia ou tratamento de uma infecção viral em um paciente, para tratamento profilático de câncer causado por oncovìrus, para identificação de um composto que altera a ligação de um oligonucleotìdeo a pelo menos um componente viral, para purificação da ligação de oligonucleotìdeos a pelo menos um componente viral e para enriquecimento de oligonucleotìdeos a partir de um agrupamento de oligonucleotìdeos |
| US20040147027A1 (en) * | 2003-01-28 | 2004-07-29 | Troy Carol M. | Complex for facilitating delivery of dsRNA into a cell and uses thereof |
| JP2008505853A (ja) * | 2004-04-13 | 2008-02-28 | クインテセンス バイオサイエンシーズ インコーポレーティッド | 細胞傷害性薬剤としての非天然のリボヌクレアーゼ複合体 |
| US9592277B2 (en) * | 2004-04-14 | 2017-03-14 | Avirid, Inc. | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
-
2005
- 2005-04-14 US US11/578,716 patent/US9592277B2/en active Active - Reinstated
- 2005-04-14 JP JP2007508498A patent/JP2007532666A/ja active Pending
- 2005-04-14 WO PCT/US2005/012532 patent/WO2005115444A2/en not_active Ceased
- 2005-04-14 CA CA2604243A patent/CA2604243C/en not_active Expired - Lifetime
- 2005-04-14 EP EP05780021A patent/EP1734991A4/en not_active Withdrawn
- 2005-04-14 AU AU2005247298A patent/AU2005247298B8/en not_active Ceased
-
2006
- 2006-10-22 IL IL178802A patent/IL178802A0/en unknown
-
2011
- 2011-02-11 AU AU2011200602A patent/AU2011200602A1/en not_active Abandoned
-
2017
- 2017-03-10 US US15/455,574 patent/US10335372B2/en not_active Expired - Lifetime
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